The initial thyroid precursor, the thyroid primordium, starts as a simple midline thickening and develops to form the thyroid diverticulum. This structure is initially hollow, although it later solidifies and becomes bilobed. The 2 lobes are located on either side of the midline and are connected via an isthmus.
Comment:
[taxon-note] "In all vertebrates the thyroid arises from the ventral aspect of the second pouch" xsd:string {source="PMID:16313389"}