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CROSS-SPECIES ANATOMY - ANNOTATIONS

The Basic subset of the UBERON integrated, cross-species anatomy ontology is downloaded weekly from http://berkeleybop.org/ontologies/uberon/basic.obo. For more information about this ontology see the "About" page on the UBERON website at http://uberon.github.io/about.html.
Term:periderm
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Accession:UBERON:0003055 term browser browse the term
Definition:The outermost layer (or layers, depending on the species) of embryonic skin, essential for the development of the epidermis and establishment of the barrier functions. The periderm derives from the outer layer of the ectoderm.
Comment:[development-note] "In some mammals, Eyelid Fusion is thought to be driven by a population of cells which are derived from the periderm, the outermost layer of the developing epidermis"; [development-note] "Originally the epidermis is one layer thick, in most vertebrates it soon becomes a two-layered structure. The outer layer gives rise to the periderm. The periderm goes through distinct developmental phases and is ultimately sloughed into the amniotic fluid when differentiation of the underlying epidermal layers is complete. The function of the periderm is not known, but is thought to be related to transport/exchange between the fetus and the amniotic fluid (http://courses.washington.edu/hubio567/devbio/periderm.html)"; [taxon-note] "In humans, the periderm is a monolayer and is shed prenatally." xsd:string {xref="PMID:35582825"}; [taxon-note] "In mice, the first non-basal layer formed at ~E9.5; it is a temporary structure composed of simple squamous epithelium that serves as the first barrier to the embryo's physical environment, exists throughout the entire keratinocyte stratification process, and sheds off at ~E17, when it is replaced by corneocytes[MP]" xsd:string {xref="PMID:35582825"}; [taxon-note] "In mice, the periderm is bilayered. It consists of the outer layer, which possesses numerous microvilli, and the inner layer that develops specific periderm granules. Both layers can be well recognized as early as at E14.5 and they are shed at different time points: the outer layer is shed in utero, in conjunction with barrier acquisition (E16-18), while the inner layer is retained postnatally."
Synonyms:related_synonym: EVL;   enveloping layer;   epitrichium
 xref: BTO:0003377;   EHDAA2:0001846;   EHDAA:6538;   FMA:295662;   NCI:C34247;   TAO:0001185;   UMLS:C1518973;   VHOG:0001680;   XAO:0000029;   ZFA:0001185
 axiom_lost: relationship type change: OBO_REL:part_of ectoderm (TAO:0000016) CHANGED TO: develops_from ectoderm (relationship type change: OBO_REL:part_of ectoderm (TAO:0000016) CHANGED TO: develops_from ectoderm (UBERON:0000924)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001185", ontology="TAO)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001185", ontology="TAO


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Term paths to the root
Path 1
Term Annotations click to browse term
  UBERON ontology 0
    anatomical entity 0
      material anatomical entity 0
        anatomical structure 0
          surface structure 0
            external integument structure 0
              periderm 0
                epidermal superficial stratum 0
                vernix caseosa 0
Path 2
Term Annotations click to browse term
  UBERON ontology 0
    anatomical entity 0
      material anatomical entity 0
        anatomical structure 0
          multicellular anatomical structure 0
            multicellular organism 0
              embryo 0
                embryonic structure 0
                  epiblast (generic) 0
                    germ layer / neural crest 0
                      germ layer 0
                        ectoderm 0
                          ectoderm-derived structure 0
                            ecto-epithelium 0
                              enveloping layer of ectoderm 0
                                outer epithelium 0
                                  periderm 0
                                    epidermal superficial stratum 0
                                    vernix caseosa 0
paths to the root