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CROSS-SPECIES ANATOMY - ANNOTATIONS

The Basic subset of the UBERON integrated, cross-species anatomy ontology is downloaded weekly from http://berkeleybop.org/ontologies/uberon/basic.obo. For more information about this ontology see the "About" page on the UBERON website at http://uberon.github.io/about.html.
Term:cerebellum
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Accession:UBERON:0002037 term browser browse the term
Definition:Part of the metencephalon that lies in the posterior cranial fossa behind the brain stem. It is concerned with the coordination of movement[MESH]. A large dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum , and formed in humans of two lateral lobes and a median lobe[BTO]. Brain structure derived from the anterior hindbrain, and perhaps including posterior midbrain. The cerebellum plays a role in somatic motor function, the control of muscle tone, and balance[ZFA].
Comment:[homology-note] "However, although the lamprey possesses a region comparable to the cerebellum and display expression of LjFgf8/17 at the MHB (midbrain hindbrain boundary), it does not have Purkinje cells and cerebellar nuclei, as well as components of the rhombic lip-derived cerebellar and pre-cerebellar systems. It is noteworthy that the latter structures require specific expression of Pax6 in the rhombic lip of the gnathostome hindbrain. Interestingly, the lamprey rhombic lip does not express Pax6. Thus, it is tempting to speculate that in vertebrate evolution the rostral hindbrain is incapable of differentiating into the cerebellum before the co-option of Pax6 in that region. In other words, cerebellum has been brought about as an evolutionary innovation in gnathostomes, based on exaptation of MHB, rhombic lip, and some regulatory gene expression already present in the vertebrate common ancestor.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000024", ontology="VHOG", source="DOI:10.1016/j.ydbio.2005.02.008 Murakami Y, Uchida K, Rijli FM and Kuratani S, Evolution of the brain developmental plan: Insights from agnathans. Developmental Biology (2005)", source="http://bgee.unil.ch/"}; [taxon-note] "The absence of a cerebellum in hagfishes and lampreys appears to be the only exception [to the rule that vertebrates possess the same number of brain divisions]. Both hagfishes and lampreys do possess a thin band of cells located medial to the lateral line centers of the medulla (Ronan and Northcutt, 1998), which has been interpreted as a primitive cerebellum (Larsell, 1967), but more recent experimental studies (Kishida et al., 1987; Weigle and Northcutt, 1998) fail to support Larsell's claim[http://icb.oxfordjournals.org/content/42/4/743.full]"
Synonyms:exact_synonym: epencephalon-1
 broad_synonym: infratentorial region
 related_synonym: corpus cerebelli;   parencephalon
 xref: AAO:0010485;   BAMS:CB;   BM:CB;   BTO:0000232;   CALOHA:TS-0125;   DHBA:10656;   EFO:0000327;   EHDAA2:0000232;   EMAPA:17787;   EV:0100293;   FMA:67944;   GAID:595;   HBA:4696;   MA:0000198;   MAT:0000110;   MBA:512;   MESH:D002531;   MIAA:0000110;   NCI:C12445;   SCTID:180924008;   TAO:0000100;   UMLS:C0007765;   UMLS:C1268981;   VHOG:0000024;   Wikipedia:Cerebellum;   XAO:0003098;   ZFA:0000100;   birnlex:1489;   neuronames:643
 relational_adjective: cerebellar
 external_ontology: dubious_for_taxon NCBITaxon:117569
 cyclic_relationship: mutually_spatially_disjoint_with mutually_spatially_disjoint_with UBERON:0001893;   mutually_spatially_disjoint_with mutually_spatially_disjoint_with UBERON:0002298
 external_ontology: never_in_taxon NCBITaxon:117565;   present_in_taxon NCBITaxon:117569;   present_in_taxon NCBITaxon:9606


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Term paths to the root
Path 1
Term Annotations click to browse term
  UBERON ontology 0
    anatomical entity 0
      material anatomical entity 0
        anatomical structure 0
          ectoderm-derived structure 0
            regional part of brain 0
              cerebellum 0
                cerebellar cortex + 0
                cerebellar nuclear complex + 0
                cerebellar plate + 0
                cerebellum fissure + 0
                cerebellum marginal layer 0
                cerebellum vasculature + 0
                cerebral blood vessel 0
                corpus cerebelli + 0
                eminentia granularis 0
                granular eminence 0
                gross anatomical parts of the cerebellum 0
                parallel fiber + 0
                spinocerebellum + 0
                superficial feature part of the cerebellum 0
                superior medullary velum 0
                valvula cerebelli + 0
                vestibulocerebellum + 0
                vestibulolateralis lobe + 0
                white matter lamina of cerebellum 0
Path 2
Term Annotations click to browse term
  UBERON ontology 0
    anatomical entity 0
      material anatomical entity 0
        anatomical structure 0
          multicellular anatomical structure 0
            multicellular organism 0
              embryo 0
                embryonic structure 0
                  epiblast (generic) 0
                    germ layer / neural crest 0
                      germ layer 0
                        ectoderm 0
                          ectoderm-derived structure 0
                            neurectoderm 0
                              presumptive neural plate 0
                                neural plate 0
                                  neural keel 0
                                    neural rod 0
                                      neural tube 0
                                        posterior neural tube 0
                                          presumptive hindbrain 0
                                            hindbrain 0
                                              segmental subdivision of hindbrain 0
                                                metencephalon 0
                                                  cerebellum 0
                                                    cerebellar cortex + 0
                                                    cerebellar nuclear complex + 0
                                                    cerebellar plate + 0
                                                    cerebellum fissure + 0
                                                    cerebellum marginal layer 0
                                                    cerebellum vasculature + 0
                                                    cerebral blood vessel 0
                                                    corpus cerebelli + 0
                                                    eminentia granularis 0
                                                    granular eminence 0
                                                    gross anatomical parts of the cerebellum 0
                                                    parallel fiber + 0
                                                    spinocerebellum + 0
                                                    superficial feature part of the cerebellum 0
                                                    superior medullary velum 0
                                                    valvula cerebelli + 0
                                                    vestibulocerebellum + 0
                                                    vestibulolateralis lobe + 0
                                                    white matter lamina of cerebellum 0
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