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CROSS-SPECIES ANATOMY - ANNOTATIONS

The Basic subset of the UBERON integrated, cross-species anatomy ontology is downloaded weekly from http://berkeleybop.org/ontologies/uberon/basic.obo. For more information about this ontology see the "About" page on the UBERON website at http://uberon.github.io/about.html.

Term:central nervous system
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Accession:UBERON:0001017 term browser browse the term
Definition:The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord.
Comment:[homology-note] "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...) (reference 1); The neural tube is destined to differentiate into the brain and spinal cord (the central nervous system) (reference 2); Taken together, our data make a very strong case that the complex molecular mediolateral architecture of the developing trunk CNS (central nervous system), as shared between Platynereis and vertebrates, was already present in their last common ancestor, Urbilateria. The concept of bilaterian nervous system centralization implies that neuron types concentrate on one side of the trunk, as is the case in vertebrates and many invertebrates including Platynereis, where they segregate and become spatially organized (as opposed to a diffuse nerve net). Our data reveal that a large part of the spatial organization of the annelid and vertebrate CNS was already present in their last common ancestor, which implies that Urbilateria had already possessed a CNS (reference 3).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000293", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28 (reference 1), ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.165 (reference 2), DOI:10.1016/j.cell.2007.02.040 Denes AS, Jekely G, Steinmetz PRH, Raible F, Snyman H, Prud'homme B, Ferrier DEK, Balavoine G and Arendt D, Molecular architecture of annelid nerve cord supports common origin of nervous system centralization in Bilateria. Cell (2007) (reference 3)", source="http://bgee.unil.ch/"}
Synonyms:exact_synonym: CNS;   systema nervosum centrale
 narrow_synonym: cerebrospinal axis
 related_synonym: neuraxis
 xref: AAO:0000090;   BAMS:CNS;   BILA:0000080;   BTO:0000227;   CALOHA:TS-0150;   EFO:0000908;   EHDAA2:0000225;   EHDAA:828;   EMAPA:16470;   EMAPA:16754;   EV:0100163;   FBbt:00005094;   FMA:55675;   GAID:570;   MA:0000167;   MAT:0000457;   MESH:D002490;   NCI:C12438;   SCTID:278199004;   TAO:0000012;   UMLS:C0927232;   VHOG:0000293;   Wikipedia:Central_nervous_system;   XAO:0000215;   ZFA:0000012;   birnlex:1099;   neuronames:854
 external_ontology: never_in_taxon NCBITaxon:147099;   present_in_taxon NCBITaxon:9606



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Term paths to the root
Path 1
Term Annotations click to browse term
  UBERON ontology 0
    anatomical entity 0
      material anatomical entity 0
        anatomical structure 0
          ectoderm-derived structure 0
            central nervous system 0
              Reissner's fiber + 0
              brain + 0
              central nervous system cell part cluster + 0
              circuit part of central nervous system + 0
              future spinal cord + 0
              ganglion of central nervous system + 0
              hindbrain-spinal cord boundary 0
              infundibular organ 0
              insect adult central nervous system + 0
              insect embryonic/larval central nervous system + 0
              insect stomatogastric nervous system 0
              lumen of central nervous system 0
              meningeal cluster + 0
              parenchyma of central nervous system + 0
              spinal cord + 0
              vasculature of central nervous system + 0
              ventricular system of central nervous system + 0
Path 2
Term Annotations click to browse term
  UBERON ontology 0
    anatomical entity 0
      material anatomical entity 0
        anatomical structure 0
          multicellular anatomical structure 0
            multicellular organism 0
              embryo 0
                embryonic structure 0
                  embryonic tissue 0
                    germ layer / neural crest 0
                      germ layer 0
                        ectoderm 0
                          future central nervous system 0
                            central nervous system 0
                              Reissner's fiber + 0
                              brain + 0
                              central nervous system cell part cluster + 0
                              circuit part of central nervous system + 0
                              future spinal cord + 0
                              ganglion of central nervous system + 0
                              hindbrain-spinal cord boundary 0
                              infundibular organ 0
                              insect adult central nervous system + 0
                              insect embryonic/larval central nervous system + 0
                              insect stomatogastric nervous system 0
                              lumen of central nervous system 0
                              meningeal cluster + 0
                              parenchyma of central nervous system + 0
                              spinal cord + 0
                              vasculature of central nervous system + 0
                              ventricular system of central nervous system + 0
paths to the root