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CROSS-SPECIES ANATOMY - ANNOTATIONS

The Basic subset of the UBERON integrated, cross-species anatomy ontology is downloaded weekly from http://berkeleybop.org/ontologies/uberon/basic.obo. For more information about this ontology see the "About" page on the UBERON website at http://uberon.github.io/about.html.

Term:endocrine pancreas
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Accession:UBERON:0000016 term browser browse the term
Definition:The part of the pancreas that is part of the endocrine system and is made up of islet cells, which produce insulin, glucagon and somatostatin.
Comment:[homology-note] "In the hagfish and lampreys (our most primitive vertebrate species of today), the first sign of 'a new organ' is found as collections of endocrine cells around the area of the bile duct connection with the duodenum. These endocrine organs are composed of 99% beta cells and 1% somatostatin-producing delta cells. Compared to the more primitive protochordates (e.g. amphioxus), this represents a stage where all previously scattered insulin-producing cells of the intestinal tissue have now quantitatively migrated to found a new organ involved in sensing blood glucose rather than gut glucose. Only later in evolution, the beta cells are joined by exocrine tissue and alpha cells (exemplified by the rat-, rabbit- and elephant-fishes). Finally, from sharks and onwards in evolution, we have the islet PP-cell entering to complete the pancreas.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000049", ontology="VHOG", source="DOI:10.1016/j.crvi.2007.03.006 Madsen OD, Pancreas phylogeny and ontogeny in relation to a 'pancreatic stem cell'. C.R. Biologies (2007)", source="http://bgee.unil.ch/"}; [taxon-note] "endocrine and exocrine pancreas are not co-associated in hagfishes or lampreys" xsd:string {source="PMID:20959416"}
Synonyms:exact_synonym: pars endocrina pancreatis
 related_synonym: endocrine part of pancreas;   islets of Langerhans part of pancreas
 xref: BTO:0000650;   CALOHA:TS-1302;   EFO:0002542;   EMAPA:35305;   EV:0100129;   FMA:16018;   MA:0001582;   MESH:D007515;   NCI:C32509;   SCTID:361339003;   TAO:0001260;   VHOG:0000049;   Wikipedia:Islets_of_Langerhans;   ZFA:0001260
 external_ontology: present_in_taxon NCBITaxon:9606



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Term paths to the root
Path 1
Term Annotations click to browse term
  UBERON ontology 0
    anatomical entity 0
      material anatomical entity 0
        anatomical structure 0
          endoderm-derived structure 0
            endocrine pancreas 0
              islet of Langerhans 0
              secretion of endocrine pancreas 0
Path 2
Term Annotations click to browse term
  UBERON ontology 0
    anatomical entity 0
      material anatomical entity 0
        anatomical structure 0
          multicellular anatomical structure 0
            multicellular organism 0
              embryo 0
                embryonic structure 0
                  presumptive structure 0
                    presumptive gut 0
                      digestive tract 0
                        subdivision of digestive tract 0
                          intestine 0
                            small intestine 0
                              duodenum 0
                                pancreatic epithelial bud 0
                                  dorsal pancreatic bud 0
                                    endocrine pancreas 0
                                      islet of Langerhans 0
                                      secretion of endocrine pancreas 0
paths to the root