Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:iron-sulfur cluster protein biogenesis pathway
go back to main search page
Accession:PW:0002634 term browser browse the term
Definition:The steps involved in the assembly and delivery of iron-sulfur (Fe-S) clusters (ISC) to Fe-S proteins. The mitochondrial ISC and the connected cytosolic assembly (CIA) pathways provide for the biogenesis of all Fe-S proteins. The Fe-S proteins participate in a broad range of important cellular processes.


show annotations for term's descendants           Sort by:
cytosolic iron-sulfur cluster protein assembly pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ciao1 cytosolic iron-sulfur assembly component 1 ISO RGD PMID:25245479 PMID:25583461 RGD:11554190, RGD:11554192 NCBI chr 3:114,458,671...114,465,928
Ensembl chr 3:114,458,655...114,467,009 		JBrowse link
G Ciao2a cytosolic iron-sulfur assembly component 2A ISO RGD PMID:25245479 PMID:25583461 RGD:11554190, RGD:11554192 NCBI chr 8:66,670,533...66,682,455
Ensembl chr 8:66,670,483...66,682,455 		JBrowse link
G Ciao2b cytosolic iron-sulfur assembly component 2B ISO RGD PMID:25245479 PMID:25583461 RGD:11554190, RGD:11554192 NCBI chr19:344,194...346,068
Ensembl chr19:344,203...346,068 		JBrowse link
G Ciao3 cytosolic iron-sulfur assembly component 3 ISO RGD PMID:25245479 PMID:25583461 RGD:11554190, RGD:11554192 NCBI chr10:14,795,888...14,804,953
Ensembl chr10:14,795,961...14,804,950 		JBrowse link
G Ciapin1 cytokine induced apoptosis inhibitor 1 ISO RGD PMID:25245479 PMID:25583461 RGD:11554190, RGD:11554192 NCBI chr19:10,179,963...10,195,511
Ensembl chr19:10,180,100...10,195,503 		JBrowse link
G Mms19 MMS19 homolog, cytosolic iron-sulfur assembly component ISO RGD PMID:25245479 PMID:25583461 RGD:11554190, RGD:11554192 NCBI chr 1:240,757,279...240,794,291
Ensembl chr 1:240,757,282...240,794,288 		JBrowse link
G Ndor1 NADPH dependent diflavin oxidoreductase 1 ISO RGD PMID:25245479 PMID:25583461 RGD:11554190, RGD:11554192 NCBI chr 3:8,062,629...8,070,873
Ensembl chr 3:8,062,630...8,070,860 		JBrowse link
G Nubp1 NUBP iron-sulfur cluster assembly factor 1 ISO RGD PMID:25245479 PMID:25583461 RGD:11554190, RGD:11554192 NCBI chr10:5,259,328...5,270,848 JBrowse link
G Nubp2 NUBP iron-sulfur cluster assembly factor 2 ISO RGD PMID:25245479 PMID:25583461 RGD:11554190, RGD:11554192 NCBI chr10:13,903,224...13,906,928
Ensembl chr10:13,903,224...13,906,969 		JBrowse link
mitochondrial iron-sulfur cluster export pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb7 ATP binding cassette subfamily B member 7 ISO RGD PMID:25245479 RGD:11554190 NCBI chr  X:69,295,598...69,436,775
Ensembl chr  X:69,295,552...69,436,858 		JBrowse link
G Gfer growth factor, augmenter of liver regeneration ISO RGD PMID:25245479 RGD:11554190 NCBI chr10:13,718,489...13,721,782
Ensembl chr10:13,718,489...13,720,869 		JBrowse link
mitochondrial iron-sulfur cluster protein biogenesis pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bola3 bolA family member 3 ISO RGD PMID:25245479 RGD:11554190 NCBI chr 4:115,853,350...115,862,797
Ensembl chr 4:115,853,350...115,862,797 		JBrowse link
G Fdx1 ferredoxin 1 ISO RGD PMID:25245479 RGD:11554190 NCBI chr 8:52,268,536...52,287,344
Ensembl chr 8:52,268,536...52,287,414 		JBrowse link
G Fdx2 ferredoxin 2 ISO RGD PMID:25245479 RGD:11554190 NCBI chr 8:19,604,916...19,609,832
Ensembl chr 8:19,604,916...19,609,849 		JBrowse link
G Fdxr ferredoxin reductase ISO RGD PMID:25245479 RGD:11554190 NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658 		JBrowse link
G Glrx5 glutaredoxin 5 ISO RGD PMID:25245479 RGD:11554190 NCBI chr 6:123,988,461...123,998,545
Ensembl chr 6:123,988,134...123,998,545 		JBrowse link
G Hscb HscB mitochondrial iron-sulfur cluster co-chaperone ISO RGD PMID:25245479 RGD:11554190 NCBI chr12:45,821,527...45,831,902
Ensembl chr12:45,821,555...45,831,909 		JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 ISO RGD PMID:25245479 RGD:11554190 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292 		JBrowse link
G Iba57 iron-sulfur cluster assembly factor IBA57 ISO RGD PMID:25245479 RGD:11554190 NCBI chr10:43,942,017...43,950,807
Ensembl chr10:43,942,017...43,950,807 		JBrowse link
G Isca1 iron-sulfur cluster assembly 1 ISO RGD PMID:25245479 RGD:11554190 NCBI chr17:4,905,291...4,917,955
Ensembl chr17:4,905,287...4,917,955 		JBrowse link
G Isca2 iron-sulfur cluster assembly 2 ISO RGD PMID:25245479 RGD:11554190 NCBI chr 6:104,418,509...104,420,019
Ensembl chr 6:104,418,454...104,420,045 		JBrowse link
G Iscu iron-sulfur cluster assembly enzyme ISO RGD PMID:25245479 RGD:11554190 NCBI chr12:42,852,305...42,858,150
Ensembl chr12:42,852,305...42,858,150 		JBrowse link
G Lyrm4 LYR motif containing 4 ISO RGD PMID:25245479 RGD:11554190 NCBI chr17:28,746,457...28,861,849
Ensembl chr17:28,746,469...28,861,750 		JBrowse link
G Nfs1 NFS1 cysteine desulfurase ISO RGD PMID:25245479 RGD:11554190 NCBI chr 3:144,637,309...144,659,660
Ensembl chr 3:144,637,309...144,659,666 		JBrowse link
G Nfu1 NFU1 iron-sulfur cluster scaffold ISO RGD PMID:25245479 RGD:11554190 NCBI chr 4:119,458,981...119,480,162
Ensembl chr 4:119,459,061...119,480,373 		JBrowse link
G Nubpl NUBP iron-sulfur cluster assembly factor like ISO RGD PMID:25245479 RGD:11554190 NCBI chr 6:69,559,278...69,781,254
Ensembl chr 6:69,559,291...69,781,253 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    classic metabolic pathway 1854
      metabolic pathway of cofactors, vitamins, nutrients 367
        iron-sulfur cluster protein biogenesis pathway 26
          cytosolic iron-sulfur cluster protein assembly pathway 9
          mitochondrial iron-sulfur cluster export pathway 2
          mitochondrial iron-sulfur cluster protein biogenesis pathway 15
Path 2
Term Annotations click to browse term
  pathway 6092
    regulatory pathway 3867
      homeostasis pathway 1773
        inorganic chemical homeostasis pathway 430
          metal homeostasis pathway 339
            iron homeostasis pathway 62
              iron utilization pathway 37
                iron-sulfur cluster protein biogenesis pathway 26
                  cytosolic iron-sulfur cluster protein assembly pathway 9
                  mitochondrial iron-sulfur cluster export pathway 2
                  mitochondrial iron-sulfur cluster protein biogenesis pathway 15
paths to the root