The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
The glyoxalase pathway is the main detoxifying route to protect against the harmful effects of methylglyoxal (MG). The highly reactive dicarbonyl compound is primarily a by-product of glycolysis, but it can also result as a by-product of fatty acid and protein metabolism. MG is also known as pyruvaldehyde or 2-oxopropanol.