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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:protease mediated signaling via protease-activated receptor 3
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Accession:PW:0002610 term browser browse the term
Definition:Protease-activated receptor 3 (PAR3/F2RL2) is primarily a target of coagulation factor 2, thrombin, but other proteases can prompt or disarm it. PAR3 is thought to not signal autonomously and require heterodimerization with other PARs.
Synonyms:related_synonym: protease mediated signaling via F2RL2;   protease mediated signaling via PAR3


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protease mediated signaling via protease-activated receptor 3 term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2 coagulation factor II, thrombin ISO RGD PMID:27126649 RGD:11352286 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G F2rl2 coagulation factor II (thrombin) receptor-like 2 ISO RGD PMID:27126649 RGD:11352286 NCBI chr 2:26,972,054...26,977,098
Ensembl chr 2:26,972,054...26,977,098 		JBrowse link
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  pathway 6097
    signaling pathway 2649
      protease mediated signaling pathway 8
        protease mediated signaling via protease-activated receptor 3 2
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