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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:protease mediated signaling via protease-activated receptor 2
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Accession:PW:0002608 term browser browse the term
Definition:Protease-activated receptor 2 (PAR2/F2RL1) is primarily a target of coagulation factor 10, but other proteases can prompt or disarm it. PAR2 signaling plays important roles in the cardiovascular and immune systems.
Synonyms:related_synonym: protease mediated signaling via F2RL1;   protease mediated signaling via PAR2


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protease mediated signaling via protease-activated receptor 2 term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F10 coagulation factor X ISO RGD PMID:27126649 RGD:11352286 NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 ISO RGD PMID:27126649 RGD:11352286 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
Term paths to the root
Path 1
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  pathway 6092
    signaling pathway 2646
      protease mediated signaling pathway 8
        protease mediated signaling via protease-activated receptor 2 2
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