Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   


The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (

Term:protease mediated signaling via protease-activated receptor 2
go back to main search page
Accession:PW:0002608 term browser browse the term
Definition:Protease-activated receptor 2 (PAR2/F2RL1) is primarily a target of coagulation factor 10, but other proteases can prompt or disarm it. PAR2 signaling plays important roles in the cardiovascular and immune systems.
Synonyms:related_synonym: protease mediated signaling via F2RL1;   protease mediated signaling via PAR2

show annotations for term's descendants           Sort by:
protease mediated signaling via protease-activated receptor 2 term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F10 coagulation factor X ISO RGD PMID:27126649 RGD:11352286 NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141
JBrowse link
G F2rl1 F2R like trypsin receptor 1 ISO RGD PMID:27126649 RGD:11352286 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6098
    signaling pathway 2648
      protease mediated signaling pathway 8
        protease mediated signaling via protease-activated receptor 2 2
paths to the root