PATHWAY ONTOLOGY - ANNOTATIONS
The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml ).
Term: 3-methylcrotonyl CoA carboxylase 1 deficiency pathway
Accession: PW:0002576
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Definition: An inheritied condition resulting from alterations in the degradation of branched-chain amino acid due to defects in the alpha subunit of methylcrotonyl CoA carboxylase (MCCC1). MCCC is a biotin-requiring enzyme in the mitochondria.
Synonyms: related_synonym: 3-methylcrotonyl CoA carboxylase type I deficiency pathway; SMP:00237
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Abat
4-aminobutyrate aminotransferase
ISO
SMPDB
SMP:00237
NCBI chrNW_004955442:9,422,849...9,516,054
Ensembl chrNW_004955442:9,422,849...9,516,103
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Acaa2
acetyl-CoA acyltransferase 2
ISO
SMPDB
SMP:00237
NCBI chrNW_004955402:34,857,317...34,885,169
Ensembl chrNW_004955402:34,857,317...34,885,169
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Acad8
acyl-CoA dehydrogenase family member 8
ISO
SMPDB
SMP:00237
NCBI chrNW_004955412:35,067,637...35,083,889
Ensembl chrNW_004955412:35,067,702...35,083,889
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Acadm
acyl-CoA dehydrogenase medium chain
ISO
SMPDB
SMP:00237
NCBI chrNW_004955423:17,173,648...17,199,189
Ensembl chrNW_004955423:17,172,779...17,199,090
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Acads
acyl-CoA dehydrogenase short chain
ISO
SMPDB
SMP:00237
NCBI chrNW_004955455:10,928,560...10,942,748
Ensembl chrNW_004955455:10,928,560...10,942,926
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Acadsb
acyl-CoA dehydrogenase short/branched chain
ISO
SMPDB
SMP:00237
NCBI chrNW_004955477:1,177,704...1,213,347
Ensembl chrNW_004955477:1,177,680...1,213,347
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Acat1
acetyl-CoA acetyltransferase 1
ISO
SMPDB
SMP:00237
NCBI chrNW_004955412:10,350,088...10,369,806
Ensembl chrNW_004955412:10,349,593...10,369,806
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Aldh2
aldehyde dehydrogenase 2 family member
ISO
SMPDB
SMP:00237
NCBI chrNW_004955482:8,352,569...8,383,097
Ensembl chrNW_004955482:8,352,569...8,384,899
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Aldh6a1
aldehyde dehydrogenase 6 family member A1
ISO
SMPDB
SMP:00237
NCBI chrNW_004955523:1,343,545...1,369,080
Ensembl chrNW_004955523:1,343,545...1,369,073
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Aox1
aldehyde oxidase 1
ISO
SMPDB
SMP:00237
NCBI chrNW_004955403:827,538...875,856
Ensembl chrNW_004955403:828,066...872,218
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Auh
AU RNA binding methylglutaconyl-CoA hydratase
ISO
SMPDB
SMP:00237
NCBI chrNW_004955515:971,778...1,124,019
Ensembl chrNW_004955515:971,800...1,123,474
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Bcat1
branched chain amino acid transaminase 1
ISO
SMPDB
SMP:00237
NCBI chrNW_004955413:19,975,395...20,087,656
Ensembl chrNW_004955413:19,981,328...20,087,638
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Bckdha
branched chain keto acid dehydrogenase E1 subunit alpha
ISO
SMPDB
SMP:00237
NCBI chrNW_004955555:334,253...357,417
Ensembl chrNW_004955555:333,642...358,799
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Bckdhb
branched chain keto acid dehydrogenase E1 subunit beta
ISO
SMPDB
SMP:00237
NCBI chrNW_004955411:8,427,875...8,626,564
Ensembl chrNW_004955411:8,437,548...8,628,363
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Dbt
dihydrolipoamide branched chain transacylase E2
ISO
SMPDB
SMP:00237
NCBI chrNW_004955435:4,975,664...5,005,126
Ensembl chrNW_004955435:4,973,830...5,017,816
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Dld
dihydrolipoamide dehydrogenase
ISO
SMPDB
SMP:00237
NCBI chrNW_004955410:12,212,981...12,238,561
Ensembl chrNW_004955410:12,212,963...12,238,561
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Echs1
enoyl-CoA hydratase, short chain 1
ISO
SMPDB
SMP:00237
NCBI chrNW_004955477:11,012,451...11,021,487
Ensembl chrNW_004955477:11,012,451...11,021,486
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Hibadh
3-hydroxyisobutyrate dehydrogenase
ISO
SMPDB
SMP:00237
NCBI chrNW_004955410:29,180,411...29,294,273
Ensembl chrNW_004955410:29,180,184...29,294,315
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Hibch
3-hydroxyisobutyryl-CoA hydrolase
ISO
SMPDB
SMP:00237
NCBI chrNW_004955403:8,752,339...8,796,693
Ensembl chrNW_004955403:8,752,309...8,792,927
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Hmgcl
3-hydroxy-3-methylglutaryl-CoA lyase
ISO
SMPDB
SMP:00237
NCBI chrNW_004955452:3,720,103...3,734,730
Ensembl chrNW_004955452:3,720,103...3,735,192
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Hmgcs2
3-hydroxy-3-methylglutaryl-CoA synthase 2
ISO
SMPDB
SMP:00237
NCBI chrNW_004955435:22,804,484...22,820,807
Ensembl chrNW_004955435:22,804,484...22,821,482
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Hsd17b10
hydroxysteroid 17-beta dehydrogenase 10
ISO
SMPDB
SMP:00237
NCBI chrNW_004955475:478,690...481,029
Ensembl chrNW_004955475:478,690...481,029
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Ivd
isovaleryl-CoA dehydrogenase
ISO
SMPDB
SMP:00237
NCBI chrNW_004955416:7,327,557...7,341,533
Ensembl chrNW_004955416:7,327,557...7,346,027
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Mccc1
methylcrotonyl-CoA carboxylase subunit 1
ISO
SMPDB
SMP:00237
NCBI chrNW_004955420:11,781,662...11,828,060
Ensembl chrNW_004955420:11,781,104...11,820,338
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Mccc2
methylcrotonyl-CoA carboxylase subunit 2
ISO
SMPDB
SMP:00237
NCBI chrNW_004955575:445,627...503,891
Ensembl chrNW_004955575:445,619...505,040
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Mcee
methylmalonyl-CoA epimerase
ISO
SMPDB
SMP:00237
NCBI chrNW_004955416:29,684,557...29,703,495
Ensembl chrNW_004955416:29,685,385...29,698,557
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Mmut
methylmalonyl-CoA mutase
ISO
SMPDB
SMP:00237
NCBI chrNW_004955411:8,363,142...8,397,839
Ensembl chrNW_004955411:8,363,142...8,399,216
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Oxct1
3-oxoacid CoA-transferase 1
ISO
SMPDB
SMP:00237
NCBI chrNW_004955426:25,885,518...25,998,187
Ensembl chrNW_004955426:25,885,518...26,003,743
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Pcca
propionyl-CoA carboxylase subunit alpha
ISO
SMPDB
SMP:00237
NCBI chrNW_004955404:10,317,640...10,719,148
Ensembl chrNW_004955404:10,317,640...10,661,496
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Pccb
propionyl-CoA carboxylase subunit beta
ISO
SMPDB
SMP:00237
NCBI chrNW_004955501:2,474,330...2,563,107
Ensembl chrNW_004955501:2,474,330...2,563,837
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