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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:dicoumarol pharmacodynamics pathway
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Accession:PW:0002497 term browser browse the term
Definition:The pathway of dicoumarol-target interaction and of the biochemical or physiological responses to drug. Dicoumarol is a naturally occurring anticoagulant that antagonizes the vitamin K dependent clotting pathway. Genetic variations can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: SMP:00270;   SMP:00656;   dicumarol pharmacodynamics pathway

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dicoumarol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955451:11,468,156...11,484,410
Ensembl chrNW_004955451:11,468,290...11,483,073 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955404:666,142...682,598
Ensembl chrNW_004955404:666,165...682,538 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955403:22,811,211...22,830,281
Ensembl chrNW_004955403:22,811,380...22,830,563 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955408:29,644,279...29,665,161
Ensembl chrNW_004955408:29,642,096...29,650,950 		JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955465:7,444,118...7,617,366
Ensembl chrNW_004955465:7,443,166...7,617,436 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955406:33,633,911...33,660,506
Ensembl chrNW_004955406:33,632,144...33,660,535 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955423:254,060...264,448
Ensembl chrNW_004955423:254,189...264,159 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955462:7,695,004...7,757,832
Ensembl chrNW_004955462:7,694,939...7,757,463 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955404:685,170...692,797
Ensembl chrNW_004955404:680,594...693,665 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955594:658,686...800,101
Ensembl chrNW_004955594:658,523...802,865 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955489:5,747,718...5,780,899
Ensembl chrNW_004955489:5,749,187...5,780,866 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955471:8,806,964...8,814,671
Ensembl chrNW_004955471:8,806,650...8,816,791 		JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955471:8,824,901...8,832,836
Ensembl chrNW_004955471:8,822,965...8,832,884 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955471:8,786,910...8,794,947
Ensembl chrNW_004955471:8,786,910...8,795,013 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955424:1,926,924...1,952,635
Ensembl chrNW_004955424:1,936,772...1,952,635 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955403:22,835,544...22,856,355
Ensembl chrNW_004955403:22,833,982...22,856,389 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955536:730,962...754,333
Ensembl chrNW_004955536:730,981...756,394 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955439:20,317,814...20,366,724
Ensembl chrNW_004955439:20,317,552...20,366,475 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955493:7,928,516...7,931,265 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 3930
    drug pathway 348
      blood and blood forming organs drug pathway 49
        antithrombotic drug pathway 49
          anticoagulant drug pathway 23
            vitamin K antagonist drug pathway 22
              dicoumarol drug pathway 20
                dicoumarol pharmacodynamics pathway 20
paths to the root