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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:heparin pharmacodynamics pathway
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Accession:PW:0002329 term browser browse the term
Definition:The pathway of heparin-target interaction and of the biochemical or physiological responses to drug. Heparin is a naturally occurring anticoagulant that binds to and activates the thrombin inhibitor antithrombin III (AT). Genetic variations can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: SMP:00274


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heparin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen, type I, alpha 1 ISO SMPDB SMP:00274 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00274 NCBI chr 8:13,087,308...13,106,676
Ensembl chr 8:13,087,308...13,106,676 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00274 NCBI chr 8:45,693,696...45,715,092
Ensembl chr 8:45,694,211...45,715,068 		JBrowse link
G F12 coagulation factor XII (Hageman factor) ISO SMPDB SMP:00274 NCBI chr13:55,565,771...55,574,617
Ensembl chr13:55,565,771...55,574,606 		JBrowse link
G F13a1 coagulation factor XIII, A1 subunit ISO SMPDB SMP:00274 NCBI chr13:37,051,150...37,234,220
Ensembl chr13:37,051,152...37,234,220 		JBrowse link
G F13b coagulation factor XIII, beta subunit ISO SMPDB SMP:00274 NCBI chr 1:139,429,285...139,451,496
Ensembl chr 1:139,429,440...139,451,490 		JBrowse link
G F2 coagulation factor II ISO SMPDB SMP:00274 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759 		JBrowse link
G F3 coagulation factor III ISO SMPDB SMP:00274 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00274 NCBI chr 1:163,979,396...164,048,539
Ensembl chr 1:163,979,407...164,047,846 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00274 NCBI chr 8:13,075,499...13,085,809
Ensembl chr 8:13,076,034...13,085,809 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00274 NCBI chr  X:74,213,950...74,426,342
Ensembl chr  X:74,216,321...74,426,221 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00274 NCBI chr  X:59,044,675...59,076,120
Ensembl chr  X:59,044,824...59,076,119 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00274 NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934 		JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00274 NCBI chr 3:82,949,553...82,957,170
Ensembl chr 3:82,947,448...82,957,170 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00274 NCBI chr 3:82,915,031...82,922,363
Ensembl chr 3:82,915,031...82,922,356 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00274 NCBI chr 6:72,391,262...72,407,696
Ensembl chr 6:72,391,291...72,407,695 		JBrowse link
G Klkb1 kallikrein B, plasma 1 ISO SMPDB SMP:00274 NCBI chr 8:45,719,725...45,747,872
Ensembl chr 8:45,719,726...45,747,896 		JBrowse link
G Plat plasminogen activator, tissue ISO SMPDB SMP:00274 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00274 NCBI chr17:12,597,496...12,638,271
Ensembl chr17:12,597,495...12,638,272 		JBrowse link
G Serpinc1 serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 ISO SMPDB SMP:00274 NCBI chr 1:160,806,153...160,830,113
Ensembl chr 1:160,806,155...160,833,433 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 ISO SMPDB SMP:00274 NCBI chr 7:127,492,235...127,494,833
Ensembl chr 7:127,485,399...127,494,626
Ensembl chr 7:127,485,399...127,494,626 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6072
    drug pathway 402
      blood and blood forming organs drug pathway 66
        antithrombotic drug pathway 66
          anticoagulant drug pathway 30
            heparin group drug pathway 21
              heparin drug pathway 21
                heparin pharmacodynamics pathway 21
paths to the root