PATHWAY ONTOLOGY - ANNOTATIONS
The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml ).
Term: AICA-ribosuria pathway
Accession: PW:0002294
browse the term
Definition: A condition resulting from alterations in the de novo purine biosynthetic pathway and due to defects in the enzyme catalyzing the final steps.
Synonyms: exact_synonym: AICAR Transformylase Inosine Monophosphate Cyclohydrolase Deficiency Pathway; AICAR Transformylase/IMP Cyclohydrloase Deficiency Pathway
related_synonym: SMP:00168
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ADA
adenosine deaminase
ISO
SMPDB
SMP:00168
NCBI chr17:47,044,492...47,072,232
Ensembl chr17:47,044,497...47,072,245
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ADCY10
adenylate cyclase 10
ISO
SMPDB
SMP:00168
NCBI chr 4:83,103,768...83,205,015
Ensembl chr 4:83,098,290...83,205,454
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ADSL
adenylosuccinate lyase
ISO
SMPDB
SMP:00168
NCBI chr 5:8,027,799...8,045,480
Ensembl chr 5:8,025,508...8,047,603
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ADSS2
adenylosuccinate synthase 2
ISO
SMPDB
SMP:00168
NCBI chr10:17,220,081...17,259,141
Ensembl chr10:17,220,207...17,259,182
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AK1
adenylate kinase 1
ISO
SMPDB
SMP:00168
NCBI chr 1:268,355,032...268,365,659
Ensembl chr 1:268,355,033...268,365,598
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AMPD1
adenosine monophosphate deaminase 1
ISO
SMPDB
SMP:00168
NCBI chr 4:105,868,834...105,892,171
Ensembl chr 4:105,868,897...105,893,769
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APRT
adenine phosphoribosyltransferase
ISO
SMPDB
SMP:00168
NCBI chr 6:890,272...893,278
Ensembl chr 6:890,831...893,276
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ATAD1
ATPase family AAA domain containing 1
ISO
SMPDB
SMP:00168
NCBI chr14:99,802,939...99,885,562
Ensembl chr14:99,815,203...99,885,160
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ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
ISO
SMPDB
SMP:00168
NCBI chr15:117,617,584...117,649,063
Ensembl chr15:117,617,502...117,649,107
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DGUOK
deoxyguanosine kinase
ISO
SMPDB
SMP:00168
NCBI chr 3:69,054,749...69,091,366
Ensembl chr 3:69,054,761...69,091,341
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ENTPD5
ectonucleoside triphosphate diphosphohydrolase 5 (inactive)
ISO
SMPDB
SMP:00168
NCBI chr 7:97,270,698...97,316,578
Ensembl chr 7:97,266,824...97,306,981
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ENTPD8
ectonucleoside triphosphate diphosphohydrolase 8
ISO
SMPDB
SMP:00168
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GART
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
ISO
SMPDB
SMP:00168
NCBI chr13:197,130,898...197,158,797
Ensembl chr13:197,130,904...197,161,891
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GDA
guanine deaminase
ISO
SMPDB
SMP:00168
NCBI chr 1:225,425,389...225,589,835
Ensembl chr 1:225,403,138...225,589,827
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GMPR
guanosine monophosphate reductase
ISO
SMPDB
SMP:00168
NCBI chr 7:12,254,393...12,298,802
Ensembl chr 7:12,254,388...12,299,531
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GMPS
guanine monophosphate synthase
ISO
SMPDB
SMP:00168
NCBI chr13:95,742,342...95,820,903
Ensembl chr13:95,738,659...95,819,759
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GUCY1A2
guanylate cyclase 1 soluble subunit alpha 2
ISO
SMPDB
SMP:00168
NCBI chr 9:62,101,581...62,510,803
Ensembl chr 9:62,101,613...62,499,581
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GUCY1B1
guanylate cyclase 1 soluble subunit beta 1
ISO
SMPDB
SMP:00168
NCBI chr 8:44,544,364...44,604,690
Ensembl chr 8:44,544,179...44,604,687
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GUK1
guanylate kinase 1
ISO
SMPDB
SMP:00168
NCBI chr 2:51,247,665...51,257,481
Ensembl chr 2:51,241,952...51,257,485
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HPRT1
hypoxanthine phosphoribosyltransferase 1
ISO
SMPDB
SMP:00168
NCBI chr X:110,321,144...110,357,902
Ensembl chr X:110,321,204...110,357,894
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IMPDH1
inosine monophosphate dehydrogenase 1
ISO
SMPDB
SMP:00168
NCBI chr18:19,979,983...19,996,432
Ensembl chr18:19,979,983...19,996,429
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ITPA
inosine triphosphatase
ISO
SMPDB
SMP:00168
NCBI chr17:32,458,351...32,474,827
Ensembl chr17:32,455,459...32,474,784
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NME6
NME/NM23 nucleoside diphosphate kinase 6
ISO
SMPDB
SMP:00168
NCBI chr13:31,048,367...31,053,285
Ensembl chr13:31,046,948...31,053,130
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NT5C2
5'-nucleotidase, cytosolic II
ISO
SMPDB
SMP:00168
NCBI chr14:114,062,451...114,167,460
Ensembl chr14:114,062,459...114,145,109
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NUDT2
nudix hydrolase 2
ISO
SMPDB
SMP:00168
NCBI chr10:32,450,986...32,466,893
Ensembl chr10:32,451,064...32,466,839
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NUDT5
nudix hydrolase 5
ISO
SMPDB
SMP:00168
NCBI chr10:59,765,444...59,787,773
Ensembl chr10:59,765,703...59,790,157
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PAICS
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
ISO
SMPDB
SMP:00168
NCBI chr 8:55,700,700...55,722,982
Ensembl chr 8:55,700,956...55,722,979
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PDE10A
phosphodiesterase 10A
ISO
SMPDB
SMP:00168
NCBI chr 1:3,120,418...3,394,236
Ensembl chr 1:2,829,411...3,392,651
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PDE4D
phosphodiesterase 4D
ISO
SMPDB
SMP:00168
NCBI chr16:37,897,300...39,406,534
Ensembl chr16:37,897,302...39,306,364
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PFAS
phosphoribosylformylglycinamidine synthase
ISO
SMPDB
SMP:00168
NCBI chr12:53,458,401...53,477,254
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PNP
purine nucleoside phosphorylase
ISO
SMPDB
SMP:00168
NCBI chr 7:78,426,838...78,447,029
Ensembl chr 7:78,424,740...78,447,012
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PPAT
phosphoribosyl pyrophosphate amidotransferase
ISO
SMPDB
SMP:00168
NCBI chr 8:55,652,194...55,701,077
Ensembl chr 8:55,654,377...55,701,077
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PRPS1L1
phosphoribosyl pyrophosphate synthetase 1 like 1
ISO
SMPDB
SMP:00168
NCBI chr 9:87,161,863...87,164,314
Ensembl chr 9:87,163,252...87,164,208
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RRM1
ribonucleotide reductase catalytic subunit M1
ISO
SMPDB
SMP:00168
NCBI chr 9:6,026,151...6,065,211
Ensembl chr 9:6,025,073...6,065,143
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RRM2
ribonucleotide reductase regulatory subunit M2
ISO
SMPDB
SMP:00168
NCBI chr 3:126,357,198...126,367,145
Ensembl chr 3:126,347,819...126,365,644
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TXN
thioredoxin
ISO
SMPDB
SMP:00168
NCBI chr 1:251,264,180...251,278,000
Ensembl chr 1:251,263,175...251,277,988
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XDH
xanthine dehydrogenase
ISO
SMPDB
SMP:00168
NCBI chr 3:107,987,060...108,052,043
Ensembl chr 3:107,987,126...108,053,169
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