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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:AICA-ribosuria pathway
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Accession:PW:0002294 term browser browse the term
Definition:A condition resulting from alterations in the de novo purine biosynthetic pathway and due to defects in the enzyme catalyzing the final steps.
Synonyms:exact_synonym: AICAR Transformylase Inosine Monophosphate Cyclohydrolase Deficiency Pathway;   AICAR Transformylase/IMP Cyclohydrloase Deficiency Pathway
 related_synonym: SMP:00168

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AICA-ribosuria pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase ISO SMPDB SMP:00168 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947 		JBrowse link
G Adcy10 adenylate cyclase 10 ISO SMPDB SMP:00168 NCBI chr13:83,701,952...83,787,010
Ensembl chr13:83,721,300...83,787,018 		JBrowse link
G Adsl adenylosuccinate lyase ISO SMPDB SMP:00168 NCBI chr 7:122,157,201...122,192,328
Ensembl chr 7:122,157,201...122,192,328 		JBrowse link
G Adss adenylosuccinate synthase ISO SMPDB SMP:00168 NCBI chr13:95,913,426...95,943,761
Ensembl chr13:95,913,426...95,943,761 		JBrowse link
G Ak1 adenylate kinase 1 ISO SMPDB SMP:00168 NCBI chr 3:11,652,143...11,659,135 JBrowse link
G Ampd1 adenosine monophosphate deaminase 1 ISO SMPDB SMP:00168 NCBI chr 2:205,568,934...205,589,961
Ensembl chr 2:205,568,935...205,590,021 		JBrowse link
G Aprt adenine phosphoribosyl transferase ISO SMPDB SMP:00168 NCBI chr19:55,387,288...55,389,256
Ensembl chr19:55,387,288...55,389,256 		JBrowse link
G Atad1 ATPase family, AAA domain containing 1 ISO SMPDB SMP:00168 NCBI chr 1:251,234,702...251,386,996
Ensembl chr 1:251,235,508...251,387,002 		JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase ISO SMPDB SMP:00168 NCBI chr 9:78,862,013...78,882,061
Ensembl chr 9:78,862,013...78,882,060 		JBrowse link
G Dguok deoxyguanosine kinase ISO SMPDB SMP:00168 NCBI chr 4:115,180,433...115,208,061
Ensembl chr 4:115,180,433...115,208,061 		JBrowse link
G Entpd5 ectonucleoside triphosphate diphosphohydrolase 5 ISO SMPDB SMP:00168 NCBI chr 6:108,087,677...108,123,811
Ensembl chr 6:108,087,418...108,120,579 		JBrowse link
G Entpd8 ectonucleoside triphosphate diphosphohydrolase 8 ISO SMPDB SMP:00168 NCBI chr 3:2,286,363...2,299,720
Ensembl chr 3:2,288,667...2,302,782 		JBrowse link
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase ISO SMPDB SMP:00168 NCBI chr11:31,780,477...31,805,728
Ensembl chr11:31,780,487...31,805,728 		JBrowse link
G Gda guanine deaminase ISO SMPDB SMP:00168 NCBI chr 1:238,982,542...239,057,663
Ensembl chr 1:238,982,392...239,057,732 		JBrowse link
G Gmpr guanosine monophosphate reductase ISO SMPDB SMP:00168 NCBI chr17:19,543,274...19,580,929
Ensembl chr17:19,543,275...19,580,929 		JBrowse link
G Gmps guanine monophosphate synthase ISO SMPDB SMP:00168 NCBI chr 2:154,555,967...154,590,662
Ensembl chr 2:154,555,871...154,590,662 		JBrowse link
G Gucy1a2 guanylate cyclase 1 soluble subunit alpha 2 ISO SMPDB SMP:00168 NCBI chr 8:408,001...899,851
Ensembl chr 8:408,001...899,974 		JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 ISO SMPDB SMP:00168 NCBI chr 2:180,976,939...181,026,001
Ensembl chr 2:180,976,939...181,026,024 		JBrowse link
G Guk1 guanylate kinase 1 ISO SMPDB SMP:00168 NCBI chr10:45,535,617...45,552,455
Ensembl chr10:45,535,627...45,543,897 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 ISO SMPDB SMP:00168 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
Ensembl chr  X:158,197,149...158,228,749 		JBrowse link
G Impdh1 inosine monophosphate dehydrogenase 1 ISO SMPDB SMP:00168 NCBI chr 4:56,478,383...56,493,987
Ensembl chr 4:56,478,384...56,493,923 		JBrowse link
G Itpa inosine triphosphatase ISO SMPDB SMP:00168 NCBI chr 3:123,209,611...123,221,266
Ensembl chr 3:123,209,608...123,221,269 		JBrowse link
G Nme6 NME/NM23 nucleoside diphosphate kinase 6 ISO SMPDB SMP:00168 NCBI chr 8:117,920,912...117,928,148
Ensembl chr 8:117,920,944...117,928,195 		JBrowse link
G Nt5c2 5'-nucleotidase, cytosolic II ISO SMPDB SMP:00168 NCBI chr 1:266,652,966...266,782,935
Ensembl chr 1:266,659,519...266,782,910 		JBrowse link
G Nudt2 nudix hydrolase 2 ISO SMPDB SMP:00168 NCBI chr 5:57,845,819...57,860,658
Ensembl chr 5:57,845,819...57,860,658 		JBrowse link
G Nudt5 nudix hydrolase 5 ISO SMPDB SMP:00168 NCBI chr17:76,387,027...76,410,309
Ensembl chr17:76,387,031...76,410,294 		JBrowse link
G Paics phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase ISO SMPDB SMP:00168 NCBI chr14:33,563,884...33,580,944
Ensembl chr14:33,563,886...33,580,566 		JBrowse link
G Pde10a phosphodiesterase 10A ISO SMPDB SMP:00168 NCBI chr 1:52,360,296...52,544,448
Ensembl chr 1:52,360,296...52,544,450 		JBrowse link
G Pde4d phosphodiesterase 4D ISO SMPDB SMP:00168 NCBI chr 2:40,219,999...41,468,551
Ensembl chr 2:40,554,146...41,464,264 		JBrowse link
G Pfas phosphoribosylformylglycinamidine synthase ISO SMPDB SMP:00168 NCBI chr10:55,571,881...55,593,384
Ensembl chr10:55,571,118...55,589,978 		JBrowse link
G Pnp purine nucleoside phosphorylase ISO SMPDB SMP:00168 NCBI chr15:27,875,883...27,883,566
Ensembl chr15:27,875,911...27,883,350 		JBrowse link
G Ppat phosphoribosyl pyrophosphate amidotransferase ISO SMPDB SMP:00168 NCBI chr14:33,580,541...33,614,919
Ensembl chr14:33,580,541...33,614,919 		JBrowse link
G Prps1l1 phosphoribosyl pyrophosphate synthetase 1-like 1 ISO SMPDB SMP:00168 NCBI chr 6:54,417,903...54,419,593
Ensembl chr 6:54,417,903...54,419,593 		JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 ISO SMPDB SMP:00168 NCBI chr 1:167,538,387...167,562,688
Ensembl chr 1:167,538,263...167,562,688 		JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 ISO SMPDB SMP:00168 NCBI chr 6:43,884,627...43,890,818
Ensembl chr 6:43,884,678...43,889,515 		JBrowse link
G Txn1 thioredoxin 1 ISO SMPDB SMP:00168 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752 		JBrowse link
G Xdh xanthine dehydrogenase ISO SMPDB SMP:00168 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6103
    disease pathway 1957
      nervous system disease pathway 761
        sensory system disease pathway 87
          AICA-ribosuria pathway 37
Path 2
Term Annotations click to browse term
  pathway 6103
    disease pathway 1957
      nutritional and metabolic disease pathway 709
        metabolic disease pathway 666
          inborn error of metabolism pathway 529
            AICA-ribosuria pathway 37
paths to the root