Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:naloxone pharmacodynamics pathway
go back to main search page
Accession:PW:0002284 term browser browse the term
Definition:The pathway of naloxone-target interaction and of the biochemical or physiological responses to drug. Naloxone is a mu-opioid receptor competitive antagonist. Genetic variations can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: SMP:00688

GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
naloxone pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenoceptor alpha 1A ISO SMPDB SMP:00688 NCBI chrNW_004624758:21,557,161...21,665,432
Ensembl chrNW_004624758:21,569,908...21,665,244 		JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00688 NCBI chrNW_004624772:12,099,523...12,127,437
Ensembl chrNW_004624772:12,099,435...12,127,737 		JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00688 NCBI chrNW_004624907:715,109...736,040
Ensembl chrNW_004624907:715,094...736,432 		JBrowse link
G Atp1a4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00688 NCBI chrNW_004624794:1,068,056...1,108,303 JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00688 NCBI chrNW_004624826:7,058,046...7,076,919
Ensembl chrNW_004624826:7,054,371...7,076,919 		JBrowse link
G Atp1b2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00688 NCBI chrNW_004624786:10,254,979...10,261,508
Ensembl chrNW_004624786:10,234,492...10,262,367 		JBrowse link
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00688 NCBI chrNW_004624730:18,510,840...18,544,528
Ensembl chrNW_004624730:18,510,844...18,544,836 		JBrowse link
G Atp1b4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00688 NCBI chrNW_004624931:234,184...255,154
Ensembl chrNW_004624931:234,103...255,189 		JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A ISO SMPDB SMP:00688 NCBI chrNW_004624901:707,322...932,658
Ensembl chrNW_004624901:708,234...932,643 		JBrowse link
G Cacna2d2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00688 NCBI chrNW_004624730:4,211,189...4,346,119
Ensembl chrNW_004624730:4,212,901...4,345,849 		JBrowse link
G Cacnb1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00688 NCBI chrNW_004624795:3,732,201...3,747,731
Ensembl chrNW_004624795:3,732,320...3,747,717 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit ISO SMPDB SMP:00688 NCBI chrNW_004624741:29,024,668...29,039,684
Ensembl chrNW_004624741:29,026,908...29,044,464 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit ISO SMPDB SMP:00688 NCBI chrNW_004624885:2,839,607...2,851,934
Ensembl chrNW_004624885:2,843,899...2,848,522 		JBrowse link
G Drd1 dopamine receptor D1 ISO SMPDB SMP:00688 NCBI chrNW_004624733:14,517,540...14,522,173
Ensembl chrNW_004624733:14,518,146...14,520,905 		JBrowse link
G Fxyd2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00688 NCBI chrNW_004624784:13,198,308...13,209,780
Ensembl chrNW_004624784:13,200,018...13,206,131 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 ISO SMPDB SMP:00688 NCBI chrNW_004624760:777,208...800,525
Ensembl chrNW_004624760:776,873...801,354 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A ISO SMPDB SMP:00688 NCBI chrNW_004624824:7,128,169...7,513,360
Ensembl chrNW_004624824:7,137,909...7,507,910 		JBrowse link
G Grin3a glutamate ionotropic receptor NMDA type subunit 3A ISO SMPDB SMP:00688 NCBI chrNW_004624758:9,579,750...9,756,396
Ensembl chrNW_004624758:9,579,752...9,756,525 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A ISO SMPDB SMP:00688 NCBI chrNW_004624815:5,817,196...5,821,197
Ensembl chrNW_004624815:5,816,601...5,820,864 		JBrowse link
G Kcnd2 potassium voltage-gated channel subfamily D member 2 ISO SMPDB SMP:00688 NCBI chrNW_004624783:15,349,416...15,892,011
Ensembl chrNW_004624783:15,351,870...15,891,057 		JBrowse link
G Kcnip2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00688 NCBI chrNW_004624831:1,301,840...1,319,487
Ensembl chrNW_004624831:1,301,598...1,319,572 		JBrowse link
G Oprm1 opioid receptor mu 1 ISO SMPDB SMP:00688 NCBI chrNW_004624785:4,147,079...4,195,712
Ensembl chrNW_004624785:4,032,689...4,196,186 		JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 ISO SMPDB SMP:00688 NCBI chrNW_004624741:18,368,976...18,643,151
Ensembl chrNW_004624741:18,368,928...18,643,600 		JBrowse link
G Pomc proopiomelanocortin ISO SMPDB SMP:00688 NCBI chrNW_004624738:7,442,223...7,448,513
Ensembl chrNW_004624738:7,442,292...7,445,020 		JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 ISO SMPDB SMP:00688 NCBI chrNW_004624731:2,254,445...2,356,174
Ensembl chrNW_004624731:2,254,445...2,355,738 		JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 ISO SMPDB SMP:00688 NCBI chrNW_004624794:8,439,609...8,449,731
Ensembl chrNW_004624794:8,439,600...8,450,179 		JBrowse link
G Slc6a2 solute carrier family 6 member 2 ISO SMPDB SMP:00688 NCBI chrNW_004624757:1,292,811...1,332,868
Ensembl chrNW_004624757:1,294,064...1,332,856 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO SMPDB SMP:00688 NCBI chrNW_004624751:694,165...720,287
Ensembl chrNW_004624751:694,099...719,465 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 ISO SMPDB SMP:00688 NCBI chrNW_004624786:2,673,285...2,711,432
Ensembl chrNW_004624786:2,672,552...2,710,914 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 3917
    drug pathway 349
      various drug pathway 29
        naloxone drug pathway 29
          naloxone pharmacodynamics pathway 29
paths to the root