PATHWAY ONTOLOGY - ANNOTATIONS
The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml ).
Term: naloxone drug pathway
Accession: PW:0002282
browse the term
Definition: The pharmacokinetics and pharmacodynamics of naloxone, a medication used to reverse the effects opioids overdose. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug.
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Adra1a
adrenoceptor alpha 1A
ISO
SMPDB
SMP:00688
NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500
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Atp1a1
ATPase Na+/K+ transporting subunit alpha 1
ISO
SMPDB
SMP:00688
NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
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Atp1a2
ATPase Na+/K+ transporting subunit alpha 2
ISO
SMPDB
SMP:00688
NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544
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Atp1a3
ATPase Na+/K+ transporting subunit alpha 3
ISO
SMPDB
SMP:00688
NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918
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Atp1a4
ATPase Na+/K+ transporting subunit alpha 4
ISO
SMPDB
SMP:00688
NCBI chr13:84,683,766...84,719,790
Ensembl chr13:84,683,768...84,719,687
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Atp1b1
ATPase Na+/K+ transporting subunit beta 1
ISO
SMPDB
SMP:00688
NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459
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Atp1b2
ATPase Na+/K+ transporting subunit beta 2
ISO
SMPDB
SMP:00688
NCBI chr10:54,318,698...54,324,933
Ensembl chr10:54,318,701...54,324,933
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Atp1b3
ATPase Na+/K+ transporting subunit beta 3
ISO
SMPDB
SMP:00688
NCBI chr 8:96,910,265...96,941,592
Ensembl chr 8:96,910,309...96,941,598 Ensembl chr 8:96,910,309...96,941,598
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Atp1b4
ATPase Na+/K+ transporting family member beta 4
ISO
SMPDB
SMP:00688
NCBI chr X:117,087,284...117,108,023
Ensembl chr X:117,057,423...117,108,020
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Cacna1a
calcium voltage-gated channel subunit alpha1 A
ISO
SMPDB
SMP:00688
NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225
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Cacna2d2
calcium voltage-gated channel auxiliary subunit alpha2delta 2
ISO
SMPDB
SMP:00688
NCBI chr 8:108,072,208...108,203,516
Ensembl chr 8:108,072,454...108,203,173
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Cacnb1
calcium voltage-gated channel auxiliary subunit beta 1
ISO
SMPDB
SMP:00688
NCBI chr10:82,998,182...83,018,838
Ensembl chr10:82,998,182...83,018,694
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Chrna4
cholinergic receptor nicotinic alpha 4 subunit
ISO
SMPDB
SMP:00688
NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
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Chrnb2
cholinergic receptor nicotinic beta 2 subunit
ISO
SMPDB
SMP:00688
NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
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Drd1
dopamine receptor D1
ISO
SMPDB
SMP:00688
NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
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Fxyd2
FXYD domain-containing ion transport regulator 2
ISO
SMPDB
SMP:00688
NCBI chr 8:45,712,901...45,720,032
Ensembl chr 8:45,712,903...45,720,203
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Grin1
glutamate ionotropic receptor NMDA type subunit 1
ISO
SMPDB
SMP:00688
NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
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Grin2a
glutamate ionotropic receptor NMDA type subunit 2A
ISO
SMPDB
SMP:00688
NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637
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Grin3a
glutamate ionotropic receptor NMDA type subunit 3A
ISO
SMPDB
SMP:00688
NCBI chr 5:64,006,847...64,206,408
Ensembl chr 5:64,009,980...64,206,085
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Htr1a
5-hydroxytryptamine receptor 1A
ISO
SMPDB
SMP:00688
NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442
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Kcnd2
potassium voltage-gated channel subfamily D member 2
ISO
SMPDB
SMP:00688
NCBI chr 4:49,775,812...50,277,746
Ensembl chr 4:49,776,246...50,277,728
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Kcnip2
potassium voltage-gated channel interacting protein 2
ISO
SMPDB
SMP:00688
NCBI chr 1:244,641,147...244,664,939
Ensembl chr 1:244,641,150...244,664,874
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Oprm1
opioid receptor, mu 1
ISO
SMPDB
SMP:00688
NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
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Pcsk2
proprotein convertase subtilisin/kexin type 2
ISO
SMPDB
SMP:00688
NCBI chr 3:130,880,422...131,183,127
Ensembl chr 3:130,880,422...131,183,127
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Pomc
proopiomelanocortin
ISO
SMPDB
SMP:00688
NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
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Scn10a
sodium voltage-gated channel alpha subunit 10
ISO
SMPDB
SMP:00688
NCBI chr 8:119,350,723...119,462,882
Ensembl chr 8:119,350,724...119,462,614
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Scn1b
sodium voltage-gated channel beta subunit 1
ISO
SMPDB
SMP:00688
NCBI chr 1:86,353,917...86,363,820
Ensembl chr 1:86,353,917...86,363,739
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Slc6a2
solute carrier family 6 member 2
ISO
SMPDB
SMP:00688
NCBI chr19:14,010,292...14,055,317
Ensembl chr19:14,010,386...14,050,357
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Slc6a3
solute carrier family 6 member 3
ISO
SMPDB
SMP:00688
NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
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Slc6a4
solute carrier family 6 member 4
ISO
SMPDB
SMP:00688
NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all