PATHWAY ONTOLOGY - ANNOTATIONS
The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml ).
Term: various drug pathway
Accession: PW:0002281
browse the term
Definition: One of the subgroups of the Therapeutic Chemical Classification System developed by WHO for grouping drugs acting as antidotes, chelators, detoxifying agents, and others. The pharmacokinetics and pharmacodynamics of such agents. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug.
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Adra1a
adrenergic receptor, alpha 1a
ISO
SMPDB
SMP:00688
NCBI chr14:66,872,705...67,009,549
Ensembl chr14:66,872,700...67,008,617
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Atp1a1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
ISO
SMPDB
SMP:00688
NCBI chr 3:101,483,535...101,512,023
Ensembl chr 3:101,483,535...101,512,000
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Atp1a2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
ISO
SMPDB
SMP:00688
NCBI chr 1:172,099,276...172,125,631
Ensembl chr 1:172,099,276...172,125,631
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Atp1a3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
ISO
SMPDB
SMP:00688
NCBI chr 7:24,677,592...24,705,338
Ensembl chr 7:24,677,592...24,705,383
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Atp1a4
ATPase, Na+/K+ transporting, alpha 4 polypeptide
ISO
SMPDB
SMP:00688
NCBI chr 1:172,051,075...172,085,991
Ensembl chr 1:172,051,080...172,085,981
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Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
ISO
SMPDB
SMP:00688
NCBI chr 1:164,264,668...164,285,924
Ensembl chr 1:164,264,678...164,285,924
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Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
ISO
SMPDB
SMP:00688
NCBI chr11:69,490,554...69,496,786
Ensembl chr11:69,490,562...69,496,768
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Atp1b3
ATPase, Na+/K+ transporting, beta 3 polypeptide
ISO
SMPDB
SMP:00688
NCBI chr 9:96,214,708...96,246,368
Ensembl chr 9:96,214,708...96,246,495
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Atp1b4
ATPase Na+/K+ transporting, beta 4 polypeptide
ISO
SMPDB
SMP:00688
NCBI chr X:37,404,999...37,425,661
Ensembl chr X:37,405,061...37,425,646
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Cacna1a
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
ISO
SMPDB
SMP:00688
NCBI chr 8:85,065,257...85,366,880
Ensembl chr 8:85,065,268...85,366,875
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Cacna2d2
calcium channel, voltage-dependent, alpha 2/delta subunit 2
ISO
SMPDB
SMP:00688
NCBI chr 9:107,276,948...107,406,545
Ensembl chr 9:107,276,811...107,406,542
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Cacnb1
calcium channel, voltage-dependent, beta 1 subunit
ISO
SMPDB
SMP:00688
NCBI chr11:97,892,339...97,913,860
Ensembl chr11:97,892,334...97,913,860
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Chrna4
cholinergic receptor, nicotinic, alpha polypeptide 4
ISO
SMPDB
SMP:00688
NCBI chr 2:180,664,104...180,685,339
Ensembl chr 2:180,660,173...180,685,339
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Chrnb2
cholinergic receptor nicotinic beta 2 subunit
ISO
SMPDB
SMP:00688
NCBI chr 3:89,660,755...89,671,939
Ensembl chr 3:89,653,502...89,671,939
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Drd1
dopamine receptor D1
ISO
SMPDB
SMP:00688
NCBI chr13:54,205,202...54,209,677
Ensembl chr13:54,205,202...54,209,724
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Fxyd2
FXYD domain-containing ion transport regulator 2
ISO
SMPDB
SMP:00688
NCBI chr 9:45,311,007...45,321,576
Ensembl chr 9:45,310,967...45,321,576
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Grin1
glutamate receptor, ionotropic, NMDA1 (zeta 1)
ISO
SMPDB
SMP:00688
NCBI chr 2:25,181,189...25,209,199
Ensembl chr 2:25,181,193...25,209,199
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Grin2a
glutamate receptor, ionotropic, NMDA2A (epsilon 1)
ISO
SMPDB
SMP:00688
NCBI chr16:9,385,765...9,813,744
Ensembl chr16:9,385,762...9,813,424
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Grin3a
glutamate receptor ionotropic, NMDA3A
ISO
SMPDB
SMP:00688
NCBI chr 4:49,661,611...49,846,023
Ensembl chr 4:49,661,611...49,845,744
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Htr1a
5-hydroxytryptamine (serotonin) receptor 1A
ISO
SMPDB
SMP:00688
NCBI chr13:105,580,040...105,584,630
Ensembl chr13:105,580,147...105,584,630
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Kcnd2
potassium voltage-gated channel, Shal-related family, member 2
ISO
SMPDB
SMP:00688
NCBI chr 6:21,212,101...21,729,804
Ensembl chr 6:21,215,502...21,729,804
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Kcnip2
Kv channel-interacting protein 2
ISO
SMPDB
SMP:00688
NCBI chr19:45,780,785...45,804,948
Ensembl chr19:45,780,278...45,804,500
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Oprm1
opioid receptor, mu 1
ISO
SMPDB
SMP:00688
NCBI chr10:6,708,593...6,988,209
Ensembl chr10:6,708,506...6,988,198
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Pcsk2
proprotein convertase subtilisin/kexin type 2
ISO
SMPDB
SMP:00688
NCBI chr 2:143,388,053...143,658,204
Ensembl chr 2:143,388,076...143,658,205
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Pomc
pro-opiomelanocortin-alpha
ISO
SMPDB
SMP:00688
NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642
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Scn10a
sodium channel, voltage-gated, type X, alpha
ISO
SMPDB
SMP:00688
NCBI chr 9:119,437,522...119,548,388
Ensembl chr 9:119,437,522...119,548,388
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Scn1b
sodium channel, voltage-gated, type I, beta
ISO
SMPDB
SMP:00688
NCBI chr 7:30,815,949...30,826,436
Ensembl chr 7:30,815,949...30,826,428
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Slc6a2
solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
ISO
SMPDB
SMP:00688
NCBI chr 8:93,687,100...93,728,295
Ensembl chr 8:93,686,707...93,728,295
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Slc6a3
solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
ISO
SMPDB
SMP:00688
NCBI chr13:73,684,270...73,726,791
Ensembl chr13:73,684,866...73,726,791
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Slc6a4
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
ISO
SMPDB
SMP:00688
NCBI chr11:76,889,423...76,923,169
Ensembl chr11:76,889,429...76,923,166
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all