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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:various drug pathway
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Accession:PW:0002281 term browser browse the term
Definition:One of the subgroups of the Therapeutic Chemical Classification System developed by WHO for grouping drugs acting as antidotes, chelators, detoxifying agents, and others. The pharmacokinetics and pharmacodynamics of such agents. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug.



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naloxone pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A EXP SMPDB SMP:00688 NCBI chr 8:26,748,150...26,867,379
Ensembl chr 8:26,748,150...26,867,278
JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 EXP SMPDB SMP:00688 NCBI chr 1:116,373,244...116,404,774
Ensembl chr 1:116,372,668...116,410,261
JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 EXP SMPDB SMP:00688 NCBI chr 1:160,115,759...160,143,591
Ensembl chr 1:160,115,759...160,143,591
JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 EXP SMPDB SMP:00688 NCBI chr19:41,966,582...41,994,230
Ensembl chr19:41,966,582...41,997,497
JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 EXP SMPDB SMP:00688 NCBI chr 1:160,151,603...160,186,980
Ensembl chr 1:160,151,586...160,186,980
JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 EXP SMPDB SMP:00688 NCBI chr 1:169,106,690...169,132,719
Ensembl chr 1:169,105,697...169,310,992
JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 EXP SMPDB SMP:00688 NCBI chr17:7,646,627...7,657,770
Ensembl chr17:7,646,627...7,657,770
JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 EXP SMPDB SMP:00688 NCBI chr 3:141,876,643...141,926,549
Ensembl chr 3:141,876,124...141,926,549
JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 EXP SMPDB SMP:00688 NCBI chr  X:120,362,089...120,383,237
Ensembl chr  X:120,362,085...120,383,249
JBrowse link
G CACNA1A calcium voltage-gated channel subunit alpha1 A EXP SMPDB SMP:00688 NCBI chr19:13,206,442...13,506,479
Ensembl chr19:13,206,442...13,624,489
JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 EXP SMPDB SMP:00688 NCBI chr 3:50,362,613...50,504,244
Ensembl chr 3:50,362,613...50,504,244
JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 EXP SMPDB SMP:00688 NCBI chr17:39,173,453...39,197,669
Ensembl chr17:39,173,453...39,197,702
JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit EXP SMPDB SMP:00688 NCBI chr20:63,343,223...63,361,349
Ensembl chr20:63,343,223...63,378,401
JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit EXP SMPDB SMP:00688 NCBI chr 1:154,567,778...154,580,013
Ensembl chr 1:154,567,778...154,580,013
JBrowse link
G DRD1 dopamine receptor D1 EXP SMPDB SMP:00688 NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182
JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 EXP SMPDB SMP:00688 NCBI chr11:117,820,057...117,828,089
Ensembl chr11:117,800,844...117,828,698
JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 EXP SMPDB SMP:00688 NCBI chr 9:137,139,154...137,168,756
Ensembl chr 9:137,138,346...137,168,756
JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A EXP SMPDB SMP:00688 NCBI chr16:9,753,404...10,182,908
Ensembl chr16:9,753,404...10,183,337
JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A EXP SMPDB SMP:00688 NCBI chr 9:101,569,352...101,738,647
Ensembl chr 9:101,569,352...101,738,647
JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A EXP SMPDB SMP:00688 NCBI chr 5:63,957,874...63,962,445
Ensembl chr 5:63,957,874...63,962,507
JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 EXP SMPDB SMP:00688 NCBI chr 7:120,272,908...120,750,337
Ensembl chr 7:120,273,175...120,750,337
JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 EXP SMPDB SMP:00688 NCBI chr10:101,825,974...101,843,800
Ensembl chr10:101,825,974...101,843,920
JBrowse link
G OPRM1 opioid receptor mu 1 EXP SMPDB SMP:00688 NCBI chr 6:154,010,496...154,246,867
Ensembl chr 6:154,010,496...154,246,867
JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 EXP SMPDB SMP:00688 NCBI chr20:17,226,107...17,484,578
Ensembl chr20:17,226,107...17,484,578
JBrowse link
G POMC proopiomelanocortin EXP SMPDB SMP:00688 NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903
JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 EXP SMPDB SMP:00688 NCBI chr 3:38,696,807...38,816,217
Ensembl chr 3:38,696,802...38,816,286
JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 EXP SMPDB SMP:00688 NCBI chr19:35,030,470...35,040,449
Ensembl chr19:35,030,470...35,040,449
JBrowse link
G SLC6A2 solute carrier family 6 member 2 EXP SMPDB SMP:00688 NCBI chr16:55,655,988...55,706,192
Ensembl chr16:55,655,988...55,707,645
JBrowse link
G SLC6A3 solute carrier family 6 member 3 EXP SMPDB SMP:00688 NCBI chr 5:1,392,794...1,445,440
Ensembl chr 5:1,392,794...1,445,440
JBrowse link
G SLC6A4 solute carrier family 6 member 4 EXP SMPDB SMP:00688 NCBI chr17:30,194,319...30,235,697
Ensembl chr17:30,194,319...30,236,002
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 5957
    drug pathway 412
      various drug pathway 30
        naloxone drug pathway + 30
paths to the root