PATHWAY ONTOLOGY - ANNOTATIONS
The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml ).
Term: various drug pathway
Accession: PW:0002281
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Definition: One of the subgroups of the Therapeutic Chemical Classification System developed by WHO for grouping drugs acting as antidotes, chelators, detoxifying agents, and others. The pharmacokinetics and pharmacodynamics of such agents. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug.
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ADRA1A
adrenoceptor alpha 1A
EXP
SMPDB
SMP:00688
NCBI chr 8:26,748,150...26,867,379
Ensembl chr 8:26,748,150...26,867,278
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ATP1A1
ATPase Na+/K+ transporting subunit alpha 1
EXP
SMPDB
SMP:00688
NCBI chr 1:116,373,244...116,404,774
Ensembl chr 1:116,372,668...116,410,261
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ATP1A2
ATPase Na+/K+ transporting subunit alpha 2
EXP
SMPDB
SMP:00688
NCBI chr 1:160,115,759...160,143,591
Ensembl chr 1:160,115,759...160,143,591
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ATP1A3
ATPase Na+/K+ transporting subunit alpha 3
EXP
SMPDB
SMP:00688
NCBI chr19:41,966,582...41,994,230
Ensembl chr19:41,966,582...41,997,497
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ATP1A4
ATPase Na+/K+ transporting subunit alpha 4
EXP
SMPDB
SMP:00688
NCBI chr 1:160,151,603...160,186,980
Ensembl chr 1:160,151,586...160,186,980
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ATP1B1
ATPase Na+/K+ transporting subunit beta 1
EXP
SMPDB
SMP:00688
NCBI chr 1:169,106,690...169,132,719
Ensembl chr 1:169,105,697...169,310,992
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ATP1B2
ATPase Na+/K+ transporting subunit beta 2
EXP
SMPDB
SMP:00688
NCBI chr17:7,646,627...7,657,770
Ensembl chr17:7,646,627...7,657,770
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ATP1B3
ATPase Na+/K+ transporting subunit beta 3
EXP
SMPDB
SMP:00688
NCBI chr 3:141,876,643...141,926,549
Ensembl chr 3:141,876,124...141,926,549
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ATP1B4
ATPase Na+/K+ transporting family member beta 4
EXP
SMPDB
SMP:00688
NCBI chr X:120,362,089...120,383,237
Ensembl chr X:120,362,085...120,383,249
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CACNA1A
calcium voltage-gated channel subunit alpha1 A
EXP
SMPDB
SMP:00688
NCBI chr19:13,206,442...13,506,479
Ensembl chr19:13,206,442...13,624,489
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CACNA2D2
calcium voltage-gated channel auxiliary subunit alpha2delta 2
EXP
SMPDB
SMP:00688
NCBI chr 3:50,362,613...50,504,244
Ensembl chr 3:50,362,613...50,504,244
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CACNB1
calcium voltage-gated channel auxiliary subunit beta 1
EXP
SMPDB
SMP:00688
NCBI chr17:39,173,453...39,197,669
Ensembl chr17:39,173,453...39,197,702
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CHRNA4
cholinergic receptor nicotinic alpha 4 subunit
EXP
SMPDB
SMP:00688
NCBI chr20:63,343,223...63,361,349
Ensembl chr20:63,343,223...63,378,401
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CHRNB2
cholinergic receptor nicotinic beta 2 subunit
EXP
SMPDB
SMP:00688
NCBI chr 1:154,567,778...154,580,013
Ensembl chr 1:154,567,778...154,580,013
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DRD1
dopamine receptor D1
EXP
SMPDB
SMP:00688
NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182
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FXYD2
FXYD domain containing ion transport regulator 2
EXP
SMPDB
SMP:00688
NCBI chr11:117,820,057...117,828,089
Ensembl chr11:117,800,844...117,828,698
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GRIN1
glutamate ionotropic receptor NMDA type subunit 1
EXP
SMPDB
SMP:00688
NCBI chr 9:137,139,154...137,168,756
Ensembl chr 9:137,138,346...137,168,756
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GRIN2A
glutamate ionotropic receptor NMDA type subunit 2A
EXP
SMPDB
SMP:00688
NCBI chr16:9,753,404...10,182,908
Ensembl chr16:9,753,404...10,183,337
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GRIN3A
glutamate ionotropic receptor NMDA type subunit 3A
EXP
SMPDB
SMP:00688
NCBI chr 9:101,569,352...101,738,647
Ensembl chr 9:101,569,352...101,738,647
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HTR1A
5-hydroxytryptamine receptor 1A
EXP
SMPDB
SMP:00688
NCBI chr 5:63,957,874...63,962,445
Ensembl chr 5:63,957,874...63,962,507
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KCND2
potassium voltage-gated channel subfamily D member 2
EXP
SMPDB
SMP:00688
NCBI chr 7:120,272,908...120,750,337
Ensembl chr 7:120,273,175...120,750,337
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KCNIP2
potassium voltage-gated channel interacting protein 2
EXP
SMPDB
SMP:00688
NCBI chr10:101,825,974...101,843,800
Ensembl chr10:101,825,974...101,843,920
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OPRM1
opioid receptor mu 1
EXP
SMPDB
SMP:00688
NCBI chr 6:154,010,496...154,246,867
Ensembl chr 6:154,010,496...154,246,867
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PCSK2
proprotein convertase subtilisin/kexin type 2
EXP
SMPDB
SMP:00688
NCBI chr20:17,226,107...17,484,578
Ensembl chr20:17,226,107...17,484,578
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POMC
proopiomelanocortin
EXP
SMPDB
SMP:00688
NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903
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SCN10A
sodium voltage-gated channel alpha subunit 10
EXP
SMPDB
SMP:00688
NCBI chr 3:38,696,807...38,816,217
Ensembl chr 3:38,696,802...38,816,286
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SCN1B
sodium voltage-gated channel beta subunit 1
EXP
SMPDB
SMP:00688
NCBI chr19:35,030,470...35,040,449
Ensembl chr19:35,030,470...35,040,449
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SLC6A2
solute carrier family 6 member 2
EXP
SMPDB
SMP:00688
NCBI chr16:55,655,988...55,706,192
Ensembl chr16:55,655,988...55,707,645
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SLC6A3
solute carrier family 6 member 3
EXP
SMPDB
SMP:00688
NCBI chr 5:1,392,794...1,445,440
Ensembl chr 5:1,392,794...1,445,440
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SLC6A4
solute carrier family 6 member 4
EXP
SMPDB
SMP:00688
NCBI chr17:30,194,319...30,235,697
Ensembl chr17:30,194,319...30,236,002
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