PATHWAY ONTOLOGY - ANNOTATIONS
The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml ).
Term: various drug pathway
Accession: PW:0002281
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Definition: One of the subgroups of the Therapeutic Chemical Classification System developed by WHO for grouping drugs acting as antidotes, chelators, detoxifying agents, and others. The pharmacokinetics and pharmacodynamics of such agents. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug.
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ADRA1A
adrenoceptor alpha 1A
ISO
SMPDB
SMP:00688
NCBI chr 8:25,947,996...26,138,022
Ensembl chr 8:22,853,677...23,044,388
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ATP1A1
ATPase Na+/K+ transporting subunit alpha 1
ISO
SMPDB
SMP:00688
NCBI chr 1:86,162,401...86,193,883
Ensembl chr 1:121,212,488...121,243,099
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ATP1A2
ATPase Na+/K+ transporting subunit alpha 2
ISO
SMPDB
SMP:00688
NCBI chr 1:135,469,495...135,497,303
Ensembl chr 1:139,390,549...139,418,303
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ATP1A3
ATPase Na+/K+ transporting subunit alpha 3
ISO
SMPDB
SMP:00688
NCBI chr19:38,854,243...38,882,034
Ensembl chr19:47,358,281...47,384,716
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ATP1A4
ATPase Na+/K+ transporting subunit alpha 4
ISO
SMPDB
SMP:00688
NCBI chr 1:135,504,929...135,540,651
Ensembl chr 1:139,426,556...139,462,393
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ATP1B1
ATPase Na+/K+ transporting subunit beta 1
ISO
SMPDB
SMP:00688
NCBI chr 1:144,592,667...144,621,052
Ensembl chr 1:148,314,793...148,342,050
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ATP1B2
ATPase Na+/K+ transporting subunit beta 2
ISO
SMPDB
SMP:00688
NCBI chr17:7,681,831...7,688,710
Ensembl chr17:7,669,626...7,673,834
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ATP1B3
ATPase Na+/K+ transporting subunit beta 3
ISO
SMPDB
SMP:00688
NCBI chr 3:138,903,371...138,954,915
Ensembl chr 3:146,500,493...146,550,164
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ATP1B4
ATPase Na+/K+ transporting family member beta 4
ISO
SMPDB
SMP:00688
NCBI chr X:109,633,770...109,654,662
Ensembl chr X:119,820,695...119,841,598
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CACNA1A
calcium voltage-gated channel subunit alpha1 A
ISO
SMPDB
SMP:00688
NCBI chr19:12,769,586...13,189,022
Ensembl chr19:13,507,102...13,804,729
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CACNA2D2
calcium voltage-gated channel auxiliary subunit alpha2delta 2
ISO
SMPDB
SMP:00688
NCBI chr 3:50,288,926...50,430,152
Ensembl chr 3:51,526,075...51,640,406
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CACNB1
calcium voltage-gated channel auxiliary subunit beta 1
ISO
SMPDB
SMP:00688
NCBI chr17:18,073,818...18,098,400
Ensembl chr17:18,349,146...18,373,338
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CHRNA4
cholinergic receptor nicotinic alpha 4 subunit
ISO
SMPDB
SMP:00688
NCBI chr20:59,730,759...59,748,678
Ensembl chr20:61,270,631...61,283,005
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CHRNB2
cholinergic receptor nicotinic beta 2 subunit
ISO
SMPDB
SMP:00688
NCBI chr 1:129,922,740...129,931,582
Ensembl chr 1:133,535,023...133,547,361
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DRD1
dopamine receptor D1
ISO
SMPDB
SMP:00688
NCBI chr 5:170,787,115...170,792,383
Ensembl chr 5:177,688,917...177,690,257
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FXYD2
FXYD domain containing ion transport regulator 2
ISO
SMPDB
SMP:00688
NCBI chr11:112,654,774...112,666,630
Ensembl chr11:116,587,226...116,595,197
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GRIN1
glutamate ionotropic receptor NMDA type subunit 1
ISO
SMPDB
SMP:00688
NCBI chr 9:108,198,350...108,228,887
Ensembl chr 9:137,168,722...137,197,382
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GRIN2A
glutamate ionotropic receptor NMDA type subunit 2A
ISO
SMPDB
SMP:00688
NCBI chr16:8,682,169...9,105,581
Ensembl chr16:9,919,143...10,336,167
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GRIN3A
glutamate ionotropic receptor NMDA type subunit 3A
ISO
SMPDB
SMP:00688
NCBI chr 9:72,773,866...72,943,790
Ensembl chr 9:100,767,715...100,941,323
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HTR1A
5-hydroxytryptamine receptor 1A
ISO
SMPDB
SMP:00688
NCBI chr 5:50,045,266...50,049,636
Ensembl chr 5:51,692,416...51,693,684
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KCND2
potassium voltage-gated channel subfamily D member 2
ISO
SMPDB
SMP:00688
NCBI chr 7:112,277,018...112,751,896
Ensembl chr 7:124,966,816...125,437,430
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KCNIP2
potassium voltage-gated channel interacting protein 2
ISO
SMPDB
SMP:00688
NCBI chr10:98,428,619...98,446,581
Ensembl chr10:101,899,898...101,918,691
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OPRM1
opioid receptor mu 1
ISO
SMPDB
SMP:00688
NCBI chr 6:151,827,323...151,937,658
Ensembl chr 6:156,517,661...157,088,251
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PCSK2
proprotein convertase subtilisin/kexin type 2
ISO
SMPDB
SMP:00688
NCBI chr20:17,184,878...17,443,355
Ensembl chr20:17,163,675...17,421,157
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POMC
proopiomelanocortin
ISO
SMPDB
SMP:00688
NCBI chr2A:25,161,668...25,165,600
Ensembl chr2A:25,258,768...25,262,706
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SCN10A
sodium voltage-gated channel alpha subunit 10
ISO
SMPDB
SMP:00688
NCBI chr 3:38,593,765...38,691,172
Ensembl chr 3:38,876,068...38,972,247
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SCN1B
sodium voltage-gated channel beta subunit 1
ISO
SMPDB
SMP:00688
NCBI chr19:31,974,499...31,984,488
Ensembl chr19:40,711,281...40,724,052
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SLC6A2
solute carrier family 6 member 2
ISO
SMPDB
SMP:00688
NCBI chr16:35,885,756...35,935,638
Ensembl chr16:54,990,773...55,040,504
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SLC6A3
solute carrier family 6 member 3
ISO
SMPDB
SMP:00688
Ensembl chr 5:1,437,567...1,488,829
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SLC6A4
solute carrier family 6 member 4
ISO
SMPDB
SMP:00688
NCBI chr17:26,546,177...26,572,301
Ensembl chr17:27,050,900...27,092,882
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