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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:2-aminoadipic 2-oxoadipic aciduria pathway
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Accession:PW:0002204 term browser browse the term
Definition:An inherited condition resulting from alterations in lysine metabolism. Mutations in the DHTKD1 gene, encoding an enzyme involved in the lysine degradation pathway, have been associated with the condition.
Synonyms:exact_synonym: 2-aminoadipic 2-oxoadipic aciduria disease pathway
 related_synonym: SMP:00719


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2-aminoadipic 2-oxoadipic aciduria pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadat aminoadipate aminotransferase ISO SMPDB SMP:00719 NCBI chr 8:60,958,877...60,998,711
Ensembl chr 8:60,958,966...60,998,711 		JBrowse link
G Aass aminoadipate-semialdehyde synthase ISO SMPDB SMP:00719 NCBI chr 6:23,072,172...23,132,985
Ensembl chr 6:23,072,172...23,132,985 		JBrowse link
G Acat1 acetyl-Coenzyme A acetyltransferase 1 ISO SMPDB SMP:00719 NCBI chr 9:53,491,822...53,521,650
Ensembl chr 9:53,491,822...53,521,682 		JBrowse link
G Aldh7a1 aldehyde dehydrogenase family 7, member A1 ISO SMPDB SMP:00719 NCBI chr18:56,657,794...56,706,112
Ensembl chr18:56,642,759...56,706,023 		JBrowse link
G Dhtkd1 dehydrogenase E1 and transketolase domain containing 1 ISO SMPDB SMP:00719 NCBI chr 2:5,901,030...5,947,648
Ensembl chr 2:5,900,926...5,947,603 		JBrowse link
G Dld dihydrolipoamide dehydrogenase ISO SMPDB SMP:00719 NCBI chr12:31,381,561...31,401,470
Ensembl chr12:31,381,276...31,401,452 		JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase ISO SMPDB SMP:00719 NCBI chr12:85,157,597...85,180,865
Ensembl chr12:85,157,607...85,181,619 		JBrowse link
G Echs1 enoyl Coenzyme A hydratase, short chain, 1, mitochondrial ISO SMPDB SMP:00719 NCBI chr 7:139,685,623...139,696,334
Ensembl chr 7:139,685,623...139,696,389 		JBrowse link
G Gcdh glutaryl-Coenzyme A dehydrogenase ISO SMPDB SMP:00719 NCBI chr 8:85,613,016...85,629,378
Ensembl chr 8:85,613,022...85,620,550 		JBrowse link
G Hadh hydroxyacyl-Coenzyme A dehydrogenase ISO SMPDB SMP:00719 NCBI chr 3:131,027,068...131,065,750
Ensembl chr 3:131,027,068...131,065,750 		JBrowse link
G Pipox pipecolic acid oxidase ISO SMPDB SMP:00719 NCBI chr11:77,771,440...77,784,698
Ensembl chr11:77,771,441...77,784,922 		JBrowse link
G Slc25a2 solute carrier family 25 (mitochondrial carrier, ornithine transporter) member 2 ISO SMPDB SMP:00719 NCBI chr18:37,770,431...37,771,776
Ensembl chr18:37,770,431...37,771,776 		JBrowse link
G Slc7a2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 ISO SMPDB SMP:00719 NCBI chr 8:41,315,404...41,375,107
Ensembl chr 8:41,315,433...41,375,345 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6072
    disease pathway 2094
      congenital disease pathway 529
        inborn genetic disease pathway 529
          inborn error of metabolism pathway 529
            inborn error of amino acid metabolism pathway 229
              2-aminoadipic 2-oxoadipic aciduria pathway 13
paths to the root