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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:2-aminoadipic 2-oxoadipic aciduria pathway
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Accession:PW:0002204 term browser browse the term
Definition:An inherited condition resulting from alterations in lysine metabolism. Mutations in the DHTKD1 gene, encoding an enzyme involved in the lysine degradation pathway, have been associated with the condition.
Synonyms:exact_synonym: 2-aminoadipic 2-oxoadipic aciduria disease pathway
 related_synonym: SMP:00719


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2-aminoadipic 2-oxoadipic aciduria pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AADAT aminoadipate aminotransferase EXP SMPDB SMP:00719 NCBI chr 4:170,060,222...170,094,292
Ensembl chr 4:170,060,222...170,091,699 		JBrowse link
G AASS aminoadipate-semialdehyde synthase EXP SMPDB SMP:00719 NCBI chr 7:122,073,549...122,144,249
Ensembl chr 7:122,064,583...122,144,308 		JBrowse link
G ACAT1 acetyl-CoA acetyltransferase 1 EXP SMPDB SMP:00719 NCBI chr11:108,116,705...108,147,603
Ensembl chr11:108,116,695...108,147,603 		JBrowse link
G ALDH7A1 aldehyde dehydrogenase 7 family member A1 EXP SMPDB SMP:00719 NCBI chr 5:126,541,841...126,595,219
Ensembl chr 5:126,531,200...126,595,362 		JBrowse link
G DHTKD1 dehydrogenase E1 and transketolase domain containing 1 EXP SMPDB SMP:00719 NCBI chr10:12,068,954...12,123,221
Ensembl chr10:12,068,954...12,123,221 		JBrowse link
G DLD dihydrolipoamide dehydrogenase EXP SMPDB SMP:00719 NCBI chr 7:107,891,107...107,921,198
Ensembl chr 7:107,891,162...107,931,730 		JBrowse link
G DLST dihydrolipoamide S-succinyltransferase EXP SMPDB SMP:00719 NCBI chr14:74,881,916...74,903,743
Ensembl chr14:74,881,891...74,903,743 		JBrowse link
G ECHS1 enoyl-CoA hydratase, short chain 1 EXP SMPDB SMP:00719 NCBI chr10:133,362,485...133,373,354
Ensembl chr10:133,362,485...133,373,354 		JBrowse link
G GCDH glutaryl-CoA dehydrogenase EXP SMPDB SMP:00719 NCBI chr19:12,891,129...12,899,999
Ensembl chr19:12,891,160...12,914,207 		JBrowse link
G HADH hydroxyacyl-CoA dehydrogenase EXP SMPDB SMP:00719 NCBI chr 4:107,989,889...108,035,171
Ensembl chr 4:107,989,714...108,035,241 		JBrowse link
G PIPOX pipecolic acid and sarcosine oxidase EXP SMPDB SMP:00719 NCBI chr17:29,043,141...29,057,216
Ensembl chr17:28,950,513...29,057,216 		JBrowse link
G SLC25A2 solute carrier family 25 member 2 EXP SMPDB SMP:00719 NCBI chr 5:141,302,635...141,304,049
Ensembl chr 5:141,302,635...141,304,049 		JBrowse link
G SLC7A2 solute carrier family 7 member 2 EXP SMPDB SMP:00719 NCBI chr 8:17,494,069...17,570,566
Ensembl chr 8:17,497,088...17,570,573 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 5958
    disease pathway 2076
      congenital disease pathway 536
        inborn genetic disease pathway 536
          inborn error of metabolism pathway 536
            inborn error of amino acid metabolism pathway 232
              2-aminoadipic 2-oxoadipic aciduria pathway 13
paths to the root