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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:presequence pathway of mitochondrial protein import
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Accession:PW:0002137 term browser browse the term
Definition:A classical pathway of mitochondrial protein import that delivers matrix resident and some of the inner membrane proteins. The precursor proteins are synthesized with an amino terminal peptide extension - the presequence. Translocase complexes, chaperones and processing enzymes cooperate in the process.


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presequence pathway of mitochondrial protein import term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNAJC19 DnaJ heat shock protein family (Hsp40) member C19 TAS RGD PMID:25542066 RGD:10412659 NCBI chr 3:180,983,709...180,989,838
Ensembl chr 3:180,983,697...180,989,774 		JBrowse link
G GRPEL1 GrpE like 1, mitochondrial TAS RGD PMID:25542066 RGD:10412659 NCBI chr 4:7,058,895...7,068,064
Ensembl chr 4:7,058,671...7,068,085 		JBrowse link
G GRPEL2 GrpE like 2, mitochondrial TAS RGD PMID:25542066 RGD:10412659 NCBI chr 5:149,345,499...149,354,583
Ensembl chr 5:149,345,430...149,354,583 		JBrowse link
G HSPA9 heat shock protein family A (Hsp70) member 9 TAS RGD PMID:25542066 RGD:10412659 NCBI chr 5:138,553,756...138,575,401
Ensembl chr 5:138,553,756...138,575,675 		JBrowse link
G IMMP1L inner mitochondrial membrane peptidase subunit 1 TAS RGD PMID:22172993 RGD:10412669 NCBI chr11:31,432,401...31,509,622
Ensembl chr11:31,432,401...31,509,645 		JBrowse link
G IMMP2L inner mitochondrial membrane peptidase subunit 2 TAS RGD PMID:22172993 RGD:10412669 NCBI chr 7:110,662,644...111,562,492
Ensembl chr 7:110,662,644...111,562,517 		JBrowse link
G MIPEP mitochondrial intermediate peptidase TAS RGD PMID:22172993 RGD:10412669 NCBI chr13:23,730,189...23,889,400
Ensembl chr13:23,730,189...23,889,400 		JBrowse link
G PAM16 presequence translocase associated motor 16 TAS RGD PMID:25542066 RGD:10412659 NCBI chr16:4,340,251...4,351,321
Ensembl chr16:4,331,549...4,355,607 		JBrowse link
G PMPCA peptidase, mitochondrial processing subunit alpha TAS RGD PMID:22172993 RGD:10412669 NCBI chr 9:136,410,658...136,423,761
Ensembl chr 9:136,410,630...136,427,992 		JBrowse link
G PMPCB peptidase, mitochondrial processing subunit beta TAS RGD PMID:22172993 RGD:10412669 NCBI chr 7:103,297,435...103,347,542
Ensembl chr 7:103,297,407...103,331,818 		JBrowse link
G ROMO1 reactive oxygen species modulator 1 TAS RGD PMID:25633533 PMID:25542066 RGD:10412658, RGD:10412659 NCBI chr20:35,699,405...35,700,980
Ensembl chr20:35,699,272...35,700,984 		JBrowse link
G TIMM17A translocase of inner mitochondrial membrane 17A TAS RGD PMID:25633533 PMID:25542066 RGD:10412658, RGD:10412659 NCBI chr 1:201,955,503...201,970,664
Ensembl chr 1:201,955,503...201,970,664 		JBrowse link
G TIMM21 translocase of inner mitochondrial membrane 21 TAS RGD PMID:25633533 PMID:25542066 RGD:10412658, RGD:10412659 NCBI chr18:74,148,523...74,160,531
Ensembl chr18:74,148,523...74,160,531 		JBrowse link
G TIMM23 translocase of inner mitochondrial membrane 23 TAS RGD PMID:25633533 PMID:25542066 RGD:10412658, RGD:10412659 NCBI chr10:45,972,489...46,003,742
Ensembl chr10:45,972,489...46,003,742 		JBrowse link
G TIMM44 translocase of inner mitochondrial membrane 44 TAS RGD PMID:25542066 RGD:10412659 NCBI chr19:7,926,718...7,943,666
Ensembl chr19:7,926,718...7,943,667 		JBrowse link
G TIMM50 translocase of inner mitochondrial membrane 50 TAS RGD PMID:25633533 PMID:25542066 RGD:10412658, RGD:10412659 NCBI chr19:39,480,838...39,493,779
Ensembl chr19:39,480,412...39,493,785 		JBrowse link
G TOMM20 translocase of outer mitochondrial membrane 20 TAS RGD PMID:25633533 PMID:25542066 RGD:10412658, RGD:10412659 NCBI chr 1:235,109,341...235,128,837
Ensembl chr 1:235,109,341...235,128,837 		JBrowse link
G TOMM22 translocase of outer mitochondrial membrane 22 TAS RGD PMID:25633533 PMID:25542066 RGD:10412658, RGD:10412659 NCBI chr22:38,681,957...38,685,421
Ensembl chr22:38,681,957...38,685,421 		JBrowse link
G TOMM40 translocase of outer mitochondrial membrane 40 TAS RGD PMID:25633533 PMID:25542066 RGD:10412658, RGD:10412659 NCBI chr19:44,891,254...44,903,689
Ensembl chr19:44,890,569...44,903,689 		JBrowse link
G TOMM5 translocase of outer mitochondrial membrane 5 TAS RGD PMID:25633533 PMID:25542066 RGD:10412658, RGD:10412659 NCBI chr 9:37,588,413...37,592,597
Ensembl chr 9:37,582,646...37,592,604 		JBrowse link
G TOMM6 translocase of outer mitochondrial membrane 6 TAS RGD PMID:25633533 PMID:25542066 RGD:10412658, RGD:10412659 NCBI chr 6:41,787,694...41,789,895
Ensembl chr 6:41,787,662...41,789,898 		JBrowse link
G TOMM7 translocase of outer mitochondrial membrane 7 TAS RGD PMID:25633533 PMID:25542066 RGD:10412658, RGD:10412659 NCBI chr 7:22,812,974...22,822,849
Ensembl chr 7:22,812,628...22,822,849 		JBrowse link
G TOMM70 translocase of outer mitochondrial membrane 70 TAS RGD PMID:25633533 PMID:25542066 RGD:10412658, RGD:10412659 NCBI chr 3:100,363,431...100,401,089
Ensembl chr 3:100,363,431...100,401,089 		JBrowse link
G XPNPEP3 X-prolyl aminopeptidase 3 TAS RGD PMID:22172993 RGD:10412669 NCBI chr22:40,857,148...40,932,815
Ensembl chr22:40,857,077...40,932,815 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 5958
    regulatory pathway 3604
      homeostasis pathway 1667
        mitochondria homeostasis pathway 112
          mitochondrial protein import pathway 43
            presequence pathway of mitochondrial protein import 24
paths to the root