Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:altered mitochondrial autophagy pathway
go back to main search page
Accession:PW:0001958 term browser browse the term
Definition:A mitophagy pathway that deviates from what its normal course should be. Mitochondrial damage and altered mitophagy pathway have been implicated in neurodegenerative diseases associated with aging, such as Parkinson, Huntington and Alzheimer diseases.
Synonyms:related_synonym: altered mitophagy pathway
View Interactive Diagram


show annotations for term's descendants           Sort by:
altered mitochondrial autophagy pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PINK1 PTEN induced kinase 1 ISO RGD PMID:24735649 RGD:10450527 NCBI chr 1:19,583,330...19,601,248
Ensembl chr 1:20,627,693...20,645,560 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:24735649 RGD:10450527 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4069
    regulatory pathway 2518
      homeostasis pathway 1306
        mitochondria homeostasis pathway 112
          mitochondrial autophagy pathway 23
            altered mitochondrial autophagy pathway 2
Path 2
Term Annotations click to browse term
  pathway 4069
    regulatory pathway 2518
      cell death pathway 186
        programmed cell death pathway 186
          non-apoptotic cell death pathway 75
            cellular autophagy pathway 75
              altered cellular autophagy 2
                altered mitochondrial autophagy pathway 2
paths to the root