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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:mercaptopurine pharmacokinetics pathway
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Accession:PW:0001943 term browser browse the term
Definition:The pathway of processing - absorption, distribution, metabolism or elimination - of mercaptopurine. Genetic variations can result in changes in the availability of the drug.
Synonyms:related_synonym: SMP:00609


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mercaptopurine pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 ISO SMPDB SMP:00609 NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375 		JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 ISO SMPDB SMP:00609 NCBI chr11:93,975,579...94,071,659
Ensembl chr11:93,978,274...94,071,655 		JBrowse link
G Adk adenosine kinase ISO SMPDB SMP:00609 NCBI chr15:2,912,543...3,295,745
Ensembl chr15:2,912,544...3,295,745 		JBrowse link
G Aox1 aldehyde oxidase 1 ISO SMPDB SMP:00609 NCBI chr 9:67,073,831...67,152,980
Ensembl chr 9:67,073,821...67,152,980 		JBrowse link
G Gmps guanine monophosphate synthase ISO SMPDB SMP:00609 NCBI chr 2:150,587,824...150,641,564
Ensembl chr 2:150,587,854...150,648,986 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 ISO SMPDB SMP:00609 NCBI chr  X:137,655,744...137,687,718
Ensembl chr  X:137,655,680...137,687,712 		JBrowse link
G Impdh1 inosine monophosphate dehydrogenase 1 ISO SMPDB SMP:00609 NCBI chr 4:58,767,230...58,782,825
Ensembl chr 4:58,767,230...58,783,124 		JBrowse link
G Ppat phosphoribosyl pyrophosphate amidotransferase ISO SMPDB SMP:00609 NCBI chr14:31,570,010...31,604,410
Ensembl chr14:31,551,388...31,604,405 		JBrowse link
G Rac1 Rac family small GTPase 1 ISO SMPDB SMP:00609 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:16,128,649...16,172,109 		JBrowse link
G Slc28a2 solute carrier family 28 member 2 ISO SMPDB SMP:00609 NCBI chr 3:129,778,425...129,841,292
Ensembl chr 3:129,807,537...129,841,291 		JBrowse link
G Slc28a3 solute carrier family 28 member 3 ISO SMPDB SMP:00609 NCBI chr17:6,068,034...6,120,421
Ensembl chr17:6,068,060...6,120,417 		JBrowse link
G Slc29a1 solute carrier family 29 member 1 ISO SMPDB SMP:00609 NCBI chr 9:22,897,099...22,911,640
Ensembl chr 9:22,902,471...22,914,620 		JBrowse link
G Slc29a2 solute carrier family 29 member 2 ISO SMPDB SMP:00609 NCBI chr 1:211,756,588...211,764,561
Ensembl chr 1:211,757,000...211,764,560 		JBrowse link
G Tpmt thiopurine S-methyltransferase ISO SMPDB SMP:00609 NCBI chr17:17,850,308...17,868,976
Ensembl chr17:17,850,279...17,868,976 		JBrowse link
G Xdh xanthine dehydrogenase ISO SMPDB SMP:00609 NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:27,282,057...27,344,350 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    drug pathway 397
      antineoplastic and immunomodulatory drug pathway 156
        immunosuppressant drug pathway 72
          mercaptopurine drug pathway 47
            mercaptopurine pharmacokinetics pathway 15
paths to the root