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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:prednisone drug pathway
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Accession:PW:0001862 term browser browse the term
Definition:The pharmacokinetics and pharmacodynamics of prednisone - a synthetic glucocorticoid that is particularly effective as a immunosuppressant drug. Both short- and long-term effects can occur. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug.


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prednisone pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 ISO SMPDB SMP:00440 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
prednisone pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 ISO SMPDB SMP:00631 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    drug pathway 397
      alimentary tract and metabolism drug pathway 80
        prednisone drug pathway 1
          prednisone pharmacodynamics pathway 1
          prednisone pharmacokinetics pathway 1
Path 2
Term Annotations click to browse term
  pathway 6092
    drug pathway 397
      antineoplastic and immunomodulatory drug pathway 156
        immunosuppressant drug pathway 72
          prednisone drug pathway 1
            prednisone pharmacodynamics pathway 1
            prednisone pharmacokinetics pathway 1
paths to the root