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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:methylmalonic acidemia pathway
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Accession:PW:0001810 term browser browse the term
Definition:An inherited condition resulting from alterations in the metabolic pathway whereby methylmalonyl-coenzyme A (CoA) is converted into succinyl-CoA.
Synonyms:exact_synonym: methylmalonic acidemia disease pathway
 related_synonym: SMP:00200;   methylmalonic aciduria disease pathway

show annotations for term's descendants           Sort by:
 
methylmalonic acidemia pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase ISO SMPDB SMP:00200 NCBI chr10:7,093,406...7,200,439
Ensembl chr10:7,093,405...7,200,499 		JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 ISO SMPDB SMP:00200 NCBI chr18:70,733,872...70,762,395
Ensembl chr18:70,733,872...70,762,395 		JBrowse link
G Acad8 acyl-CoA dehydrogenase family, member 8 ISO SMPDB SMP:00200 NCBI chr 8:28,023,401...28,044,967
Ensembl chr 8:28,024,123...28,044,876 		JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain ISO SMPDB SMP:00200 NCBI chr 2:260,124,418...260,148,589
Ensembl chr 2:260,124,418...260,148,589 		JBrowse link
G Acads acyl-CoA dehydrogenase short chain ISO SMPDB SMP:00200 NCBI chr12:47,254,503...47,263,747
Ensembl chr12:47,254,484...47,263,747 		JBrowse link
G Acadsb acyl-CoA dehydrogenase, short/branched chain ISO SMPDB SMP:00200 NCBI chr 1:201,981,362...202,022,771
Ensembl chr 1:201,981,357...202,021,008 		JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 ISO SMPDB SMP:00200 NCBI chr 8:58,166,990...58,195,884
Ensembl chr 8:58,166,990...58,195,884 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member ISO SMPDB SMP:00200 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752 		JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 ISO SMPDB SMP:00200 NCBI chr 6:108,146,552...108,167,185
Ensembl chr 6:108,146,582...108,167,185 		JBrowse link
G Aox1 aldehyde oxidase 1 ISO SMPDB SMP:00200 NCBI chr 9:64,929,682...65,007,872
Ensembl chr 9:64,929,721...65,007,870 		JBrowse link
G Auh AU RNA binding methylglutaconyl-CoA hydratase ISO SMPDB SMP:00200 NCBI chr17:12,310,178...12,405,224
Ensembl chr17:12,310,214...12,405,205 		JBrowse link
G Bcat1 branched chain amino acid transaminase 1 ISO SMPDB SMP:00200 NCBI chr 4:179,259,305...179,340,021
Ensembl chr 4:179,259,308...179,339,795 		JBrowse link
G Bckdha branched chain keto acid dehydrogenase E1 subunit alpha ISO SMPDB SMP:00200 NCBI chr 1:82,423,291...82,452,094
Ensembl chr 1:82,423,277...82,452,281 		JBrowse link
G Bckdhb branched chain keto acid dehydrogenase E1 subunit beta ISO SMPDB SMP:00200 NCBI chr 8:91,464,229...91,656,134
Ensembl chr 8:91,464,229...91,656,134 		JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 ISO SMPDB SMP:00200 NCBI chr 2:219,563,783...219,592,651
Ensembl chr 2:219,563,783...219,592,650 		JBrowse link
G Dld dihydrolipoamide dehydrogenase ISO SMPDB SMP:00200 NCBI chr 6:50,597,677...50,618,694
Ensembl chr 6:50,597,677...50,618,694 		JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 ISO SMPDB SMP:00200 NCBI chr 1:212,570,213...212,579,040
Ensembl chr 1:212,570,195...212,579,057 		JBrowse link
G Hibadh 3-hydroxyisobutyrate dehydrogenase ISO SMPDB SMP:00200 NCBI chr 4:82,604,369...82,702,429
Ensembl chr 4:82,604,373...82,702,429 		JBrowse link
G Hibch 3-hydroxyisobutyryl-CoA hydrolase ISO SMPDB SMP:00200 NCBI chr 9:53,446,185...53,526,727
Ensembl chr 9:53,446,194...53,526,728 		JBrowse link
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase ISO SMPDB SMP:00200 NCBI chr 5:154,294,841...154,308,582
Ensembl chr 5:154,294,806...154,308,640 		JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 ISO SMPDB SMP:00200 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423 		JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 ISO SMPDB SMP:00200 NCBI chr  X:21,696,796...21,699,241
Ensembl chr  X:21,696,772...21,699,241 		JBrowse link
G Ivd isovaleryl-CoA dehydrogenase ISO SMPDB SMP:00200 NCBI chr 3:110,669,355...110,689,789
Ensembl chr 3:110,669,312...110,690,173 		JBrowse link
G Mccc1 methylcrotonoyl-CoA carboxylase 1 ISO SMPDB SMP:00200 NCBI chr 2:122,550,777...122,690,540
Ensembl chr 2:122,550,775...122,690,617 		JBrowse link
G Mccc2 methylcrotonoyl-CoA carboxylase 2 ISO SMPDB SMP:00200 NCBI chr 2:30,175,017...30,246,028
Ensembl chr 2:30,175,018...30,246,010 		JBrowse link
G Mcee methylmalonyl CoA epimerase ISO SMPDB SMP:00200 NCBI chr 1:125,229,487...125,252,692
Ensembl chr 1:125,229,469...125,252,666 		JBrowse link
G Mmut methylmalonyl-CoA mutase ISO SMPDB SMP:00200 NCBI chr 9:23,323,934...23,352,144
Ensembl chr 9:23,323,936...23,352,668 		JBrowse link
G Oxct1 3-oxoacid CoA transferase 1 ISO SMPDB SMP:00200 NCBI chr 2:53,859,738...54,007,733
Ensembl chr 2:53,859,737...54,007,756 		JBrowse link
G Pcca propionyl-CoA carboxylase subunit alpha ISO SMPDB SMP:00200 NCBI chr15:108,960,509...109,306,879
Ensembl chr15:108,960,562...109,306,603 		JBrowse link
G Pccb propionyl-CoA carboxylase subunit beta ISO SMPDB SMP:00200 NCBI chr 8:109,368,887...109,418,871
Ensembl chr 8:109,368,624...109,418,872 		JBrowse link
methylmalonic aciduria, cobalamin-related pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase ISO SMPDB SMP:00201 NCBI chr10:7,093,406...7,200,439
Ensembl chr10:7,093,405...7,200,499 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha ISO SMPDB SMP:00201 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910 		JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain ISO SMPDB SMP:00201 NCBI chr 2:260,124,418...260,148,589
Ensembl chr 2:260,124,418...260,148,589 		JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 ISO SMPDB SMP:00201 NCBI chr 8:58,166,990...58,195,884
Ensembl chr 8:58,166,990...58,195,884 		JBrowse link
G Acss1 acyl-CoA synthetase short-chain family member 1 ISO SMPDB SMP:00201 NCBI chr 3:146,420,346...146,470,293
Ensembl chr 3:146,420,346...146,470,293 		JBrowse link
G Acss3 acyl-CoA synthetase short-chain family member 3 ISO SMPDB SMP:00201 NCBI chr 7:49,047,022...49,250,953
Ensembl chr 7:49,047,013...49,250,957 		JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 ISO SMPDB SMP:00201 NCBI chr 6:108,146,552...108,167,185
Ensembl chr 6:108,146,582...108,167,185 		JBrowse link
G Bckdha branched chain keto acid dehydrogenase E1 subunit alpha ISO SMPDB SMP:00201 NCBI chr 1:82,423,291...82,452,094
Ensembl chr 1:82,423,277...82,452,281 		JBrowse link
G Bckdhb branched chain keto acid dehydrogenase E1 subunit beta ISO SMPDB SMP:00201 NCBI chr 8:91,464,229...91,656,134
Ensembl chr 8:91,464,229...91,656,134 		JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 ISO SMPDB SMP:00201 NCBI chr 2:219,563,783...219,592,651
Ensembl chr 2:219,563,783...219,592,650 		JBrowse link
G Dld dihydrolipoamide dehydrogenase ISO SMPDB SMP:00201 NCBI chr 6:50,597,677...50,618,694
Ensembl chr 6:50,597,677...50,618,694 		JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 ISO SMPDB SMP:00201 NCBI chr 1:212,570,213...212,579,040
Ensembl chr 1:212,570,195...212,579,057 		JBrowse link
G Hibch 3-hydroxyisobutyryl-CoA hydrolase ISO SMPDB SMP:00201 NCBI chr 9:53,446,185...53,526,727
Ensembl chr 9:53,446,194...53,526,728 		JBrowse link
G Ldhal6b lactate dehydrogenase A-like 6B ISO SMPDB SMP:00201 NCBI chr 1:46,307,853...46,309,276 JBrowse link
G Mcee methylmalonyl CoA epimerase ISO SMPDB SMP:00201 NCBI chr 1:125,229,487...125,252,692
Ensembl chr 1:125,229,469...125,252,666 		JBrowse link
G Mlycd malonyl-CoA decarboxylase ISO SMPDB SMP:00201 NCBI chr19:52,032,950...52,048,773
Ensembl chr19:52,032,886...52,048,753 		JBrowse link
G Mmut methylmalonyl-CoA mutase ISO SMPDB SMP:00201 NCBI chr 9:23,323,934...23,352,144
Ensembl chr 9:23,323,936...23,352,668 		JBrowse link
G Pcca propionyl-CoA carboxylase subunit alpha ISO SMPDB SMP:00201 NCBI chr15:108,960,509...109,306,879
Ensembl chr15:108,960,562...109,306,603 		JBrowse link
G Pccb propionyl-CoA carboxylase subunit beta ISO SMPDB SMP:00201 NCBI chr 8:109,368,887...109,418,871
Ensembl chr 8:109,368,624...109,418,872 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6105
    disease pathway 1955
      congenital disease pathway 529
        inborn genetic disease pathway 529
          inborn error of metabolism pathway 529
            inborn error of amino acid metabolism pathway 229
              methylmalonic acidemia pathway 35
                methylmalonic aciduria, cobalamin-related pathway 19
paths to the root