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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:S-adenosylmethionine homeostasis pathway
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Accession:PW:0001693 term browser browse the term
Definition:Those pathways that involve the balanced generation and utilization of S-adenosylmethionine (AdoMet or SAM). SAM is a universal methyl donor and at the cross roads of metabolism, gene expression regulation and cellular signaling.
Synonyms:related_synonym: AdoMet homeostasis pathway;   SAM homeostasis pathway


show annotations for term's descendants           Sort by:
altered DNA modification pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MBD4 methyl-CpG binding domain 4, DNA glycosylase ISO in silico assessment of loss of DNA-protein interactions and observed enhancement of DNA repair capacity (DRC) in the context of nucleotide excision repair (NER) pathway for SNP RGD PMID:24004570 RGD:9588971 NCBI chr20:5,716,162...5,725,068
Ensembl chr20:5,716,239...5,724,881 		JBrowse link
altered folate cycle metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH1L1 aldehyde dehydrogenase 1 family member L1 ISO RGD PMID:22353665 RGD:7242562 NCBI chr20:52,722...99,180
Ensembl chr20:61,349...99,160 		JBrowse link
G DHFR dihydrofolate reductase ISO RGD PMID:22108709 RGD:7242557 NCBI chr 3:26,521,214...26,556,065 JBrowse link
G LOC609612 folate receptor alpha ISO RGD PMID:22108709 RGD:7242557 NCBI chr21:25,944,350...25,951,010 JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 ISO RGD PMID:22108709 RGD:7242557 NCBI chr 8:38,831,672...38,889,607
Ensembl chr 8:38,831,860...38,889,453 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase ISO RGD PMID:22108709 RGD:7242557 NCBI chr 2:84,445,526...84,457,435
Ensembl chr 2:84,380,919...84,536,818 		JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase ISO RGD PMID:22108709 RGD:7242557 NCBI chr 4:3,219,851...3,328,000
Ensembl chr 4:3,215,090...3,328,115 		JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase ISO RGD PMID:22108709 RGD:7242557 NCBI chr34:6,068,572...6,119,580
Ensembl chr34:6,070,046...6,098,312 		JBrowse link
G SLC46A1 solute carrier family 46 member 1 ISO RGD PMID:22108709 RGD:7242557 NCBI chr 9:42,638,670...42,650,241
Ensembl chr 9:42,643,328...42,650,188 		JBrowse link
altered folate mediated one-carbon metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 ISO RGD PMID:22353665 RGD:7242562 NCBI chr 8:38,831,672...38,889,607
Ensembl chr 8:38,831,860...38,889,453 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase ISO RGD PMID:22353665 RGD:7242562 NCBI chr 2:84,445,526...84,457,435
Ensembl chr 2:84,380,919...84,536,818 		JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase ISO RGD PMID:22353665 RGD:7242562 NCBI chr 4:3,219,851...3,328,000
Ensembl chr 4:3,215,090...3,328,115 		JBrowse link
DNA modification pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXXC1 CXXC finger protein 1 ISO RGD PMID:23697932 RGD:9479164 NCBI chr 7:78,591,288...78,596,642
Ensembl chr 7:78,591,434...78,596,643 		JBrowse link
G DNMT1 DNA methyltransferase 1 ISO RGD PMID:22770212 PMID:24825349 RGD:8695943 RGD:8695944 NCBI chr20:50,872,213...50,928,352
Ensembl chr20:50,879,527...50,928,029 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha ISO RGD PMID:22770212 PMID:24825349 RGD:8695943 RGD:8695944 NCBI chr17:19,489,524...19,563,074
Ensembl chr17:19,492,193...19,563,902 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta ISO RGD PMID:22770212 PMID:24825349 RGD:8695943 RGD:8695944 NCBI chr24:22,096,386...22,123,378
Ensembl chr24:22,096,349...22,122,900 		JBrowse link
G EBF1 EBF transcription factor 1 ISO RGD PMID:24825349 RGD:8695944 NCBI chr 4:51,378,314...51,765,768
Ensembl chr 4:51,379,233...51,763,035 		JBrowse link
G KDM2A lysine demethylase 2A ISO RGD PMID:23697932 RGD:9479164 NCBI chr18:50,178,511...50,294,097
Ensembl chr18:50,181,024...50,291,127 		JBrowse link
G KDM2B lysine demethylase 2B ISO RGD PMID:23697932 RGD:9479164 NCBI chr26:7,625,857...7,746,049
Ensembl chr26:7,598,931...7,745,113 		JBrowse link
G KMT2A lysine methyltransferase 2A ISO RGD PMID:23697932 RGD:9479164 NCBI chr 5:15,212,559...15,302,825
Ensembl chr 5:15,217,348...15,270,971 		JBrowse link
G KMT2C lysine methyltransferase 2C ISO RGD PMID:23697932 RGD:9479164 NCBI chr16:15,962,045...16,117,601
Ensembl chr16:15,963,901...16,158,408 		JBrowse link
G MBD1 methyl-CpG binding domain protein 1 ISO RGD PMID:23324617 RGD:8695954 NCBI chr 7:78,597,688...78,611,303
Ensembl chr 7:78,597,746...78,651,472 		JBrowse link
G MBD2 methyl-CpG binding domain protein 2 ISO RGD PMID:23324617 RGD:8695954 NCBI chr 1:21,232,260...21,283,687
Ensembl chr 1:21,235,967...21,283,346 		JBrowse link
G MBD4 methyl-CpG binding domain 4, DNA glycosylase ISO RGD PMID:23324617 RGD:8695954 NCBI chr20:5,716,162...5,725,068
Ensembl chr20:5,716,239...5,724,881 		JBrowse link
G MECP2 methyl-CpG binding protein 2 ISO RGD PMID:23324617 RGD:8695954 NCBI chr  X:121,866,721...121,876,088
Ensembl chr  X:121,873,218...121,932,994 		JBrowse link
G NANOG Nanog homeobox ISO RGD PMID:24825349 RGD:8695944 NCBI chr27:37,262,558...37,266,449 JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase ISO RGD PMID:24825349 RGD:8695944 NCBI chr  X:55,821,227...55,857,597
Ensembl chr  X:55,821,234...55,855,502 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma ISO RGD PMID:24825349 RGD:8695944 NCBI chr20:6,134,618...6,265,481
Ensembl chr20:6,050,357...6,207,981 		JBrowse link
G PRDM14 PR/SET domain 14 ISO RGD PMID:24825349 RGD:8695944 NCBI chr29:19,203,798...19,220,149
Ensembl chr29:19,203,807...19,220,518 		JBrowse link
G SIN3A SIN3 transcription regulator family member A ISO RGD PMID:24825349 RGD:8695944 NCBI chr30:38,231,844...38,306,665
Ensembl chr30:38,232,680...38,382,635 		JBrowse link
G SPI1 Spi-1 proto-oncogene ISO RGD PMID:24825349 RGD:8695944 NCBI chr18:42,253,849...42,269,497
Ensembl chr18:42,253,811...42,269,727 		JBrowse link
G TET1 tet methylcytosine dioxygenase 1 ISO RGD PMID:22770212 PMID:24825349 RGD:8695943 RGD:8695944 NCBI chr 4:19,759,661...19,898,345
Ensembl chr 4:19,768,137...19,889,907 		JBrowse link
G TET2 tet methylcytosine dioxygenase 2 ISO RGD PMID:22770212 PMID:24825349 RGD:8695943 RGD:8695944 NCBI chr32:26,021,745...26,145,109
Ensembl chr32:26,059,693...26,143,536 		JBrowse link
G TET3 tet methylcytosine dioxygenase 3 ISO RGD PMID:22770212 PMID:23697932 PMID:24825349 RGD:8695943 RGD:8695944 RGD:9479164 NCBI chr17:48,976,510...49,083,454
Ensembl chr17:48,981,558...49,082,675 		JBrowse link
G UHRF1 ubiquitin like with PHD and ring finger domains 1 ISO RGD PMID:23324617 RGD:8695954 NCBI chr20:54,858,673...54,889,769
Ensembl chr20:54,859,947...54,889,907 		JBrowse link
G UHRF2 ubiquitin like with PHD and ring finger domains 2 ISO RGD PMID:23324617 RGD:8695954 NCBI chr11:27,406,275...27,474,971
Ensembl chr11:27,405,977...27,623,005 		JBrowse link
G ZBTB33 zinc finger and BTB domain containing 33 ISO RGD PMID:23324617 RGD:8695954 NCBI chr  X:92,243,159...92,250,940
Ensembl chr  X:92,245,000...92,247,984 		JBrowse link
G ZBTB38 zinc finger and BTB domain containing 38 ISO RGD PMID:23324617 RGD:8695954 NCBI chr23:37,283,794...37,344,316
Ensembl chr23:37,297,101...37,341,506 		JBrowse link
G ZBTB4 zinc finger and BTB domain containing 4 ISO RGD PMID:23324617 RGD:8695954 NCBI chr 5:32,384,353...32,401,658
Ensembl chr 5:32,384,353...32,399,306 		JBrowse link
G ZFP57 ZFP57 zinc finger protein ISO RGD PMID:23324617 RGD:8695954 NCBI chr35:26,267,358...26,269,429 JBrowse link
folate cycle metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH1L1 aldehyde dehydrogenase 1 family member L1 ISO RGD PMID:22353665 RGD:7242562 NCBI chr20:52,722...99,180
Ensembl chr20:61,349...99,160 		JBrowse link
G AMT aminomethyltransferase ISO RGD PMID:20645850 RGD:7242560 NCBI chr20:39,815,449...39,820,907
Ensembl chr20:39,815,814...39,820,506 		JBrowse link
G DHFR dihydrofolate reductase ISO RGD PMID:22108709 RGD:7242557 NCBI chr 3:26,521,214...26,556,065 JBrowse link
G DLD dihydrolipoamide dehydrogenase ISO RGD PMID:20645850 RGD:7242560 NCBI chr18:12,703,340...12,734,408
Ensembl chr18:12,703,341...12,734,479 		JBrowse link
G DMGDH dimethylglycine dehydrogenase ISO RGD PMID:20645850 RGD:7242560 NCBI chr 3:27,789,089...27,857,348
Ensembl chr 3:27,790,324...27,856,601 		JBrowse link
G FOLH1B folate hydrolase 1B ISO RGD PMID:16859665 PMID:20814827 RGD:7242426 RGD:7242559 NCBI chr21:10,401,129...10,466,162
Ensembl chr21:10,203,492...10,466,161 		JBrowse link
G FPGS folylpolyglutamate synthase ISO RGD PMID:16859665 RGD:7242559 NCBI chr 9:55,590,092...55,612,639
Ensembl chr 9:55,585,970...55,599,028 		JBrowse link
G GCSH glycine cleavage system protein H ISO RGD PMID:20645850 RGD:7242560 NCBI chr 5:70,745,591...70,757,292
Ensembl chr 5:70,745,258...70,756,830 		JBrowse link
G GGH gamma-glutamyl hydrolase ISO RGD PMID:16859665 RGD:7242559 NCBI chr29:13,143,881...13,165,028
Ensembl chr29:13,134,232...13,165,028 		JBrowse link
G GLDC glycine decarboxylase ISO RGD PMID:20645850 RGD:7242560 NCBI chr11:27,491,639...27,584,450
Ensembl chr11:27,414,834...27,584,450 		JBrowse link
G LOC476816 folate receptor beta ISO RGD PMID:22108709 RGD:7242557 NCBI chr21:25,917,476...25,923,267 JBrowse link
G LOC609612 folate receptor alpha ISO RGD PMID:22108709 RGD:7242557 NCBI chr21:25,944,350...25,951,010 JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 ISO RGD PMID:22108709 RGD:7242557 NCBI chr 8:38,831,672...38,889,607
Ensembl chr 8:38,831,860...38,889,453 		JBrowse link
G MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like ISO RGD PMID:22108709 RGD:7242557 NCBI chr 1:41,316,247...41,495,226
Ensembl chr 1:41,309,419...41,495,216 		JBrowse link
G MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase ISO RGD PMID:20645850 PMID:22108709 RGD:7242557 RGD:7242560 NCBI chr17:48,882,838...48,896,816
Ensembl chr17:48,883,724...48,941,949 		JBrowse link
G MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like ISO RGD PMID:22108709 RGD:7242557 NCBI chr13:62,670,543...62,803,270
Ensembl chr13:62,670,462...62,803,519 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase ISO RGD PMID:22108709 RGD:7242557 NCBI chr 2:84,445,526...84,457,435
Ensembl chr 2:84,380,919...84,536,818 		JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase ISO RGD PMID:22108709 RGD:7242557 NCBI chr 4:3,219,851...3,328,000
Ensembl chr 4:3,215,090...3,328,115 		JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase ISO RGD PMID:22108709 RGD:7242557 NCBI chr34:6,068,572...6,119,580
Ensembl chr34:6,070,046...6,098,312 		JBrowse link
G SARDH sarcosine dehydrogenase ISO RGD PMID:20645850 RGD:7242560 NCBI chr 9:50,030,397...50,093,556
Ensembl chr 9:50,030,707...50,091,553 		JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 ISO RGD PMID:22108709 RGD:7242557 NCBI chr 5:41,221,531...41,248,653
Ensembl chr 5:41,221,562...41,253,166 		JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 ISO RGD PMID:20645850 PMID:22108709 RGD:7242557 RGD:7242560 NCBI chr10:1,357,347...1,362,511
Ensembl chr10:1,356,706...1,362,305 		JBrowse link
G SLC19A1 solute carrier family 19 member 1 ISO RGD PMID:20814827 PMID:22108709 RGD:7242426 RGD:7242557 NCBI chr31:38,958,332...38,971,091
Ensembl chr31:38,967,013...38,971,094 		JBrowse link
G SLC25A32 solute carrier family 25 member 32 ISO RGD PMID:22332074 RGD:7242561 NCBI chr13:4,821,065...4,835,113
Ensembl chr13:4,648,759...4,835,023 		JBrowse link
G SLC46A1 solute carrier family 46 member 1 ISO RGD PMID:20814827 PMID:22108709 RGD:7242426 RGD:7242557 NCBI chr 9:42,638,670...42,650,241
Ensembl chr 9:42,643,328...42,650,188 		JBrowse link
folate mediated one-carbon metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH1L1 aldehyde dehydrogenase 1 family member L1 ISO RGD PMID:14729668 RGD:1547843 NCBI chr20:52,722...99,180
Ensembl chr20:61,349...99,160 		JBrowse link
G ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase ISO RGD PMID:9332377 PMID:22332074 RGD:70804 RGD:7242561 NCBI chr37:22,420,645...22,446,769
Ensembl chr37:22,420,603...22,446,697 		JBrowse link
G DHFR dihydrofolate reductase ISO RGD PMID:11502523 PMID:22332074 RGD:1298877 RGD:7242561 NCBI chr 3:26,521,214...26,556,065 JBrowse link
G DMGDH dimethylglycine dehydrogenase ISO RGD PMID:15358367 RGD:1547831 NCBI chr 3:27,789,089...27,857,348
Ensembl chr 3:27,790,324...27,856,601 		JBrowse link
G FOLH1B folate hydrolase 1B ISO RGD PMID:9501243 RGD:728645 NCBI chr21:10,401,129...10,466,162
Ensembl chr21:10,203,492...10,466,161 		JBrowse link
G GNMT glycine N-methyltransferase ISO RGD PMID:8278367 RGD:1545057 NCBI chr12:11,500,363...11,503,075
Ensembl chr12:11,500,392...11,503,481 		JBrowse link
G LOC487740 trifunctional purine biosynthetic protein adenosine-3 ISO RGD PMID:12450384 PMID:22332074 RGD:1547842 RGD:7242561 NCBI chr31:29,032,399...29,063,706 JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 ISO RGD PMID:2186031 PMID:22332074 RGD:1299513 RGD:7242561 NCBI chr 8:38,831,672...38,889,607
Ensembl chr 8:38,831,860...38,889,453 		JBrowse link
G MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase ISO RGD PMID:9454603 RGD:1540378 NCBI chr17:48,882,838...48,896,816
Ensembl chr17:48,883,724...48,941,949 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase ISO RGD PMID:11933257 PMID:22332074 RGD:1535021 RGD:7242561 NCBI chr 2:84,445,526...84,457,435
Ensembl chr 2:84,380,919...84,536,818 		JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase ISO RGD PMID:15845641 PMID:20814827 RGD:1359026 RGD:7242426 NCBI chr 4:3,219,851...3,328,000
Ensembl chr 4:3,215,090...3,328,115 		JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase ISO RGD PMID:20814827 RGD:7242426 NCBI chr34:6,068,572...6,119,580
Ensembl chr34:6,070,046...6,098,312 		JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 ISO RGD PMID:3110140 PMID:15671219 PMID:22332074 RGD:1359815 RGD:2300383 RGD:7242561 NCBI chr 5:41,221,531...41,248,653
Ensembl chr 5:41,221,562...41,253,166 		JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 ISO RGD PMID:3110140 PMID:15671219 PMID:22332074 RGD:1359815 RGD:2300383 RGD:7242561 NCBI chr10:1,357,347...1,362,511
Ensembl chr10:1,356,706...1,362,305 		JBrowse link
G TYMS thymidylate synthetase ISO RGD PMID:9894005 PMID:22332074 RGD:1545055 RGD:7242561 NCBI chr 7:67,487,927...67,497,747
Ensembl chr 7:67,487,927...67,497,747 		JBrowse link
folate metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH1L1 aldehyde dehydrogenase 1 family member L1 ISO SMPDB
RGD		 PMID:14729668 RGD:1547843 SMP:00053 NCBI chr20:52,722...99,180
Ensembl chr20:61,349...99,160 		JBrowse link
G DHFR dihydrofolate reductase ISO SMPDB
RGD		 PMID:11502523 RGD:1298877 SMP:00053 NCBI chr 3:26,521,214...26,556,065 JBrowse link
G DMGDH dimethylglycine dehydrogenase ISO RGD PMID:15358367 RGD:1547831 NCBI chr 3:27,789,089...27,857,348
Ensembl chr 3:27,790,324...27,856,601 		JBrowse link
G FOLH1B folate hydrolase 1B ISO RGD PMID:9816319 RGD:151347637 NCBI chr21:10,401,129...10,466,162
Ensembl chr21:10,203,492...10,466,161 		JBrowse link
G FPGS folylpolyglutamate synthase ISO SMPDB SMP:00053 NCBI chr 9:55,590,092...55,612,639
Ensembl chr 9:55,585,970...55,599,028 		JBrowse link
G FTCD formimidoyltransferase cyclodeaminase ISO SMPDB SMP:00053 NCBI chr31:39,451,557...39,464,249
Ensembl chr31:39,275,159...39,464,715 		JBrowse link
G GGH gamma-glutamyl hydrolase ISO SMPDB SMP:00053 NCBI chr29:13,143,881...13,165,028
Ensembl chr29:13,134,232...13,165,028 		JBrowse link
G GNMT glycine N-methyltransferase ISO RGD PMID:15347642 RGD:1359070 NCBI chr12:11,500,363...11,503,075
Ensembl chr12:11,500,392...11,503,481 		JBrowse link
G LOC476816 folate receptor beta ISO RGD PMID:8445646 RGD:1540379 NCBI chr21:25,917,476...25,923,267 JBrowse link
G LOC487740 trifunctional purine biosynthetic protein adenosine-3 ISO RGD PMID:12450384 RGD:1547842 NCBI chr31:29,032,399...29,063,706 JBrowse link
G MTFMT mitochondrial methionyl-tRNA formyltransferase ISO SMPDB SMP:00053 NCBI chr30:29,388,600...29,415,578
Ensembl chr30:29,388,649...29,450,430 		JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 ISO SMPDB
RGD		 PMID:2186031 RGD:1299513 SMP:00053 NCBI chr 8:38,831,672...38,889,607
Ensembl chr 8:38,831,860...38,889,453 		JBrowse link
G MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like ISO SMPDB SMP:00053 NCBI chr 1:41,316,247...41,495,226
Ensembl chr 1:41,309,419...41,495,216 		JBrowse link
G MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase ISO SMPDB
RGD		 PMID:9454603 RGD:1540378 SMP:00053 NCBI chr17:48,882,838...48,896,816
Ensembl chr17:48,883,724...48,941,949 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase ISO SMPDB
RGD		 PMID:11933257 RGD:1535021 SMP:00053 NCBI chr 2:84,445,526...84,457,435
Ensembl chr 2:84,380,919...84,536,818 		JBrowse link
G MTHFS methenyltetrahydrofolate synthetase ISO SMPDB SMP:00053 NCBI chr 3:57,480,935...57,514,836 JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase ISO RGD PMID:15845641 RGD:1359026 NCBI chr 4:3,219,851...3,328,000
Ensembl chr 4:3,215,090...3,328,115 		JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase ISO RGD PMID:15979034 RGD:1359037 NCBI chr34:6,068,572...6,119,580
Ensembl chr34:6,070,046...6,098,312 		JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 ISO RGD PMID:15671219 RGD:1359815 NCBI chr 5:41,221,531...41,248,653
Ensembl chr 5:41,221,562...41,253,166 		JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 ISO RGD PMID:15671219 RGD:1359815 NCBI chr10:1,357,347...1,362,511
Ensembl chr10:1,356,706...1,362,305 		JBrowse link
G SLC19A1 solute carrier family 19 member 1 ISO RGD PMID:11600421 RGD:735239 NCBI chr31:38,958,332...38,971,091
Ensembl chr31:38,967,013...38,971,094 		JBrowse link
G SLC46A1 solute carrier family 46 member 1 ISO SMPDB SMP:00053 NCBI chr 9:42,638,670...42,650,241
Ensembl chr 9:42,643,328...42,650,188 		JBrowse link
G TYMS thymidylate synthetase ISO RGD PMID:9894005 RGD:1545055 NCBI chr 7:67,487,927...67,497,747
Ensembl chr 7:67,487,927...67,497,747 		JBrowse link
histone modification pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AEBP2 AE binding protein 2 ISO RGD PMID:24148750 RGD:9479059 NCBI chr27:27,654,141...27,722,922
Ensembl chr27:27,656,406...27,722,433 		JBrowse link
G APLF aprataxin and PNKP like factor ISO RGD PMID:23288364 RGD:9068945 NCBI chr10:67,454,500...67,522,659
Ensembl chr10:67,454,356...67,521,761 		JBrowse link
G ASF1A anti-silencing function 1A histone chaperone ISO RGD PMID:23288364 RGD:9068945 NCBI chr 1:58,821,324...58,834,935
Ensembl chr 1:58,821,521...58,946,475 		JBrowse link
G ASF1B anti-silencing function 1B histone chaperone ISO RGD PMID:23288364 RGD:9068945 NCBI chr20:48,398,615...48,406,889 JBrowse link
G ASH1L ASH1 like histone lysine methyltransferase ISO RGD PMID:23200123 RGD:7242632 NCBI chr 7:42,046,262...42,227,737
Ensembl chr 7:42,046,569...42,225,456 		JBrowse link
G ASH2L ASH2 like, histone lysine methyltransferase complex subunit ISO RGD PMID:22663077 RGD:9479053 NCBI chr16:27,334,419...27,366,994
Ensembl chr16:27,334,420...27,366,950 		JBrowse link
G BAP1 BRCA1 associated deubiquitinase 1 ISO RGD PMID:24647359 RGD:9479061 NCBI chr20:37,355,499...37,364,298
Ensembl chr20:37,355,494...37,511,125 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 ISO RGD PMID:23642229 RGD:9479074 NCBI chr 9:2,930,308...2,959,307 JBrowse link
G BMI1 BMI1 proto-oncogene, polycomb ring finger ISO RGD PMID:23473600 PMID:25065329 RGD:9479058 RGD:9479060 NCBI chr 2:10,818,232...10,828,473
Ensembl chr 2:10,818,232...10,833,613 		JBrowse link
G BPTF bromodomain PHD finger transcription factor ISO RGD PMID:23642229 PMID:24686119 RGD:9479074 RGD:9479075 NCBI chr 9:12,586,107...12,703,296
Ensembl chr 9:12,590,333...12,703,422 		JBrowse link
G BRCC3 BRCA1/BRCA2-containing complex subunit 3 ISO RGD PMID:24647359 RGD:9479061 NCBI chr  X:123,081,262...123,143,509
Ensembl chr  X:123,081,050...123,140,133 		JBrowse link
G BRD1 bromodomain containing 1 ISO RGD PMID:24686119 RGD:9479075 NCBI chr10:17,361,043...17,396,725
Ensembl chr10:17,361,117...17,395,928 		JBrowse link
G BRD2 bromodomain containing 2 ISO RGD PMID:24686119 RGD:9479075 NCBI chr12:2,534,034...2,546,029
Ensembl chr12:2,534,034...2,546,029 		JBrowse link
G BRD3 bromodomain containing 3 ISO RGD PMID:24686119 RGD:9479075 NCBI chr 9:50,290,488...50,322,243
Ensembl chr 9:50,288,240...50,322,127 		JBrowse link
G BRD4 bromodomain containing 4 ISO RGD PMID:24686119 RGD:9479075 NCBI chr20:46,844,795...46,927,620
Ensembl chr20:46,891,514...46,927,608 		JBrowse link
G BRD7 bromodomain containing 7 ISO RGD PMID:24686119 RGD:9479075 NCBI chr 2:64,966,636...65,002,800
Ensembl chr 2:64,966,392...65,002,799 		JBrowse link
G BRDT bromodomain testis associated ISO RGD PMID:24686119 RGD:9479075 NCBI chr 6:56,918,939...56,977,355
Ensembl chr 6:56,919,195...56,965,638 		JBrowse link
G BRF1 BRF1 RNA polymerase III transcription initiation factor subunit ISO RGD PMID:23642229 RGD:9479074 NCBI chr 8:72,588,578...72,632,259
Ensembl chr 8:72,588,693...72,632,263 		JBrowse link
G CARM1 coactivator associated arginine methyltransferase 1 ISO RGD PMID:24583552 RGD:9479047 NCBI chr20:50,328,466...50,371,845
Ensembl chr20:50,331,030...50,348,195 		JBrowse link
G CBX2 chromobox 2 ISO RGD PMID:23473600 PMID:25065329 RGD:9479058 RGD:9479060 NCBI chr 9:1,847,867...1,855,923
Ensembl chr 9:1,850,874...1,856,328 		JBrowse link
G CBX4 chromobox 4 ISO RGD PMID:23473600 PMID:25065329 RGD:9479058 RGD:9479060 NCBI chr 9:1,799,847...1,807,500
Ensembl chr 9:1,802,047...1,807,690 		JBrowse link
G CBX5 chromobox 5 ISO RGD PMID:23642229 RGD:9479074 NCBI chr27:1,020,500...1,058,027
Ensembl chr27:1,039,594...1,049,788 		JBrowse link
G CBX6 chromobox 6 ISO RGD PMID:23473600 PMID:25065329 RGD:9479058 RGD:9479060 NCBI chr10:25,967,305...25,973,489
Ensembl chr10:25,967,300...25,988,497 		JBrowse link
G CBX7 chromobox 7 ISO RGD PMID:23473600 PMID:25065329 RGD:9479058 RGD:9479060 NCBI chr10:25,876,022...25,896,284
Ensembl chr10:25,876,016...25,893,501 		JBrowse link
G CBX8 chromobox 8 ISO RGD PMID:23473600 PMID:25065329 RGD:9479058 RGD:9479060 NCBI chr 9:1,839,701...1,842,355
Ensembl chr 9:1,839,096...1,843,099 		JBrowse link
G CHAF1A chromatin assembly factor 1 subunit A ISO RGD PMID:23288364 RGD:9068945 NCBI chr20:55,248,286...55,276,425
Ensembl chr20:55,248,288...55,276,900 		JBrowse link
G CHAF1B chromatin assembly factor 1 subunit B ISO RGD PMID:23288364 RGD:9068945 NCBI chr31:31,599,840...31,620,436
Ensembl chr31:31,600,448...31,619,784 		JBrowse link
G CHD1 chromodomain helicase DNA binding protein 1 ISO RGD PMID:23642229 RGD:9479074 NCBI chr 3:11,288,873...11,359,972
Ensembl chr 3:11,288,244...11,359,208 		JBrowse link
G CREBBP CREB binding protein ISO RGD PMID:21151613 PMID:24686119 RGD:9104959 RGD:9479075 NCBI chr 6:37,410,201...37,536,688
Ensembl chr 6:37,409,930...37,534,176 		JBrowse link
G CXXC1 CXXC finger protein 1 ISO RGD PMID:22663077 RGD:9479053 NCBI chr 7:78,591,288...78,596,642
Ensembl chr 7:78,591,434...78,596,643 		JBrowse link
G DAXX death domain associated protein ISO RGD PMID:23288364 RGD:9068945 NCBI chr12:2,755,960...2,760,687
Ensembl chr12:2,755,960...2,761,340 		JBrowse link
G DOT1L DOT1 like histone lysine methyltransferase ISO RGD PMID:23200123 RGD:7242632 NCBI chr20:56,805,030...56,868,771
Ensembl chr20:56,803,242...56,852,539 		JBrowse link
G DPF3 double PHD fingers 3 ISO RGD PMID:23642229 RGD:9479074 NCBI chr 8:46,020,591...46,178,600
Ensembl chr 8:46,030,180...46,140,948 		JBrowse link
G DPY30 dpy-30 histone methyltransferase complex regulatory subunit ISO RGD PMID:22663077 RGD:9479053 NCBI chr17:25,368,121...25,380,882
Ensembl chr17:25,368,142...25,378,356 		JBrowse link
G EHMT1 euchromatic histone lysine methyltransferase 1 ISO RGD PMID:23200123 RGD:7242632 NCBI chr 9:48,031,593...48,110,954
Ensembl chr 9:48,032,709...48,175,828 		JBrowse link
G EHMT2 euchromatic histone lysine methyltransferase 2 ISO RGD PMID:23200123 PMID:23642229 RGD:7242632 RGD:9479074 NCBI chr12:1,341,202...1,354,602
Ensembl chr12:1,341,191...1,354,584 		JBrowse link
G EP300 E1A binding protein p300 ISO RGD PMID:21151613 RGD:9104959 NCBI chr10:24,076,538...24,156,708
Ensembl chr10:24,077,971...24,156,396 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO RGD PMID:23200123 RGD:7242632 NCBI chr16:1,926,443...1,991,995
Ensembl chr16:1,925,956...1,991,838 		JBrowse link
G H2AX H2A.X variant histone ISO RGD PMID:24614311 RGD:9075965 NCBI chr 5:14,765,625...14,766,590
Ensembl chr 5:14,766,126...14,766,557 		JBrowse link
G H2AZ1 H2A.Z variant histone 1 ISO RGD PMID:24696452 RGD:9074213 NCBI chr32:21,889,890...21,892,165
Ensembl chr32:21,889,877...21,892,102 		JBrowse link
G H3-3A H3.3 histone A ISO RGD PMID:24614311 RGD:9075965 NCBI chr 7:38,797,168...38,805,417
Ensembl chr 7:38,797,448...38,805,416 		JBrowse link
G HAT1 histone acetyltransferase 1 ISO RGD PMID:21151613 RGD:9104959 NCBI chr36:16,310,269...16,378,029
Ensembl chr36:16,310,710...16,378,017 		JBrowse link
G HCFC1 host cell factor C1 ISO RGD PMID:22663077 RGD:9479053 NCBI chr  X:121,790,585...121,815,395
Ensembl chr  X:121,791,660...121,814,715 		JBrowse link
G HDAC1 histone deacetylase 1 ISO RGD PMID:21151613 RGD:9104959 NCBI chr 2:68,901,339...68,936,473
Ensembl chr 2:68,901,651...68,936,186 		JBrowse link
G HDAC10 histone deacetylase 10 ISO RGD PMID:21151613 RGD:9104959 NCBI chr10:16,996,307...17,001,365
Ensembl chr10:16,995,762...17,078,262 		JBrowse link
G HDAC11 histone deacetylase 11 ISO RGD PMID:21151613 RGD:9104959 NCBI chr20:3,792,832...3,815,922
Ensembl chr20:3,792,693...3,837,192 		JBrowse link
G HDAC2 histone deacetylase 2 ISO RGD PMID:21151613 RGD:9104959 NCBI chr12:70,053,822...70,083,491
Ensembl chr12:70,053,297...70,103,578 		JBrowse link
G HDAC3 histone deacetylase 3 ISO RGD PMID:21151613 RGD:9104959 NCBI chr 2:36,583,283...36,598,121
Ensembl chr 2:36,583,283...36,597,682 		JBrowse link
G HDAC4 histone deacetylase 4 ISO RGD PMID:21151613 RGD:9104959 NCBI chr25:49,318,621...49,545,314
Ensembl chr25:49,317,349...49,453,478 		JBrowse link
G HDAC5 histone deacetylase 5 ISO RGD PMID:21151613 RGD:9104959 NCBI chr 9:19,261,075...19,297,669
Ensembl chr 9:19,260,893...19,297,623 		JBrowse link
G HDAC6 histone deacetylase 6 ISO RGD PMID:21151613 RGD:9104959 NCBI chr  X:42,004,268...42,024,726
Ensembl chr  X:42,004,591...42,024,427 		JBrowse link
G HDAC7 histone deacetylase 7 ISO RGD PMID:21151613 RGD:9104959 NCBI chr27:6,941,287...6,968,370
Ensembl chr27:6,929,829...6,979,317 		JBrowse link
G HDAC8 histone deacetylase 8 ISO RGD PMID:21151613 RGD:9104959 NCBI chr  X:56,357,205...56,574,443
Ensembl chr  X:56,357,177...56,574,401 		JBrowse link
G HDAC9 histone deacetylase 9 ISO RGD PMID:21151613 RGD:9104959 NCBI chr14:32,469,349...33,310,439
Ensembl chr14:32,588,414...33,304,387 		JBrowse link
G HIRA histone cell cycle regulator ISO RGD PMID:23288364 RGD:9068945 NCBI chr26:29,777,984...29,867,992
Ensembl chr26:29,778,086...29,867,559 		JBrowse link
G HJURP Holliday junction recognition protein ISO RGD PMID:23288364 RGD:9068945 NCBI chr25:45,215,165...45,230,603
Ensembl chr25:45,215,380...45,230,547 		JBrowse link
G ING2 inhibitor of growth family member 2 ISO RGD PMID:23642229 RGD:9479074 NCBI chr16:46,843,478...46,850,856
Ensembl chr16:46,845,289...46,850,637 		JBrowse link
G JMJD1C jumonji domain containing 1C ISO RGD PMID:23200123 RGD:7242632 NCBI chr 4:15,006,670...15,261,139
Ensembl chr 4:15,007,508...15,261,691 		JBrowse link
G KAT2A lysine acetyltransferase 2A ISO RGD PMID:21151613 PMID:23642229 RGD:9104959 RGD:9479074 NCBI chr 9:20,778,434...20,787,057
Ensembl chr 9:20,779,042...20,787,067 		JBrowse link
G KAT2B lysine acetyltransferase 2B ISO RGD PMID:21151613 RGD:9104959 NCBI chr23:23,166,722...23,242,447
Ensembl chr23:23,168,600...23,233,478 		JBrowse link
G KAT5 lysine acetyltransferase 5 ISO RGD PMID:21151613 RGD:9104959 NCBI chr18:51,499,615...51,507,434
Ensembl chr18:51,499,938...51,576,699 		JBrowse link
G KAT6A lysine acetyltransferase 6A ISO RGD PMID:21151613 RGD:9104959 NCBI chr16:23,604,629...23,717,047
Ensembl chr16:23,604,200...23,724,252 		JBrowse link
G KAT6B lysine acetyltransferase 6B ISO RGD PMID:21151613 RGD:9104959 NCBI chr 4:25,131,580...25,303,355
Ensembl chr 4:25,131,844...25,301,825 		JBrowse link
G KAT7 lysine acetyltransferase 7 ISO RGD PMID:21151613 RGD:9104959 NCBI chr 9:25,841,916...25,875,245
Ensembl chr 9:25,842,054...25,873,674 		JBrowse link
G KAT8 lysine acetyltransferase 8 ISO RGD PMID:21151613 RGD:9104959 NCBI chr 6:17,114,528...17,125,287
Ensembl chr 6:17,114,528...17,125,203 		JBrowse link
G KDM1A lysine demethylase 1A ISO RGD PMID:23200123 RGD:7242632 NCBI chr 2:76,313,742...76,375,716
Ensembl chr 2:76,156,434...76,375,632 		JBrowse link
G KDM1B lysine demethylase 1B ISO RGD PMID:23200123 RGD:7242632 NCBI chr35:16,954,483...17,014,261
Ensembl chr35:16,921,095...17,012,527 		JBrowse link
G KDM2A lysine demethylase 2A ISO RGD PMID:23200123 RGD:7242632 NCBI chr18:50,178,511...50,294,097
Ensembl chr18:50,181,024...50,291,127 		JBrowse link
G KDM2B lysine demethylase 2B ISO RGD PMID:23200123 RGD:7242632 NCBI chr26:7,625,857...7,746,049
Ensembl chr26:7,598,931...7,745,113 		JBrowse link
G KDM3A lysine demethylase 3A ISO RGD PMID:23200123 RGD:7242632 NCBI chr17:38,690,962...38,744,507
Ensembl chr17:38,690,979...38,743,739 		JBrowse link
G KDM3B lysine demethylase 3B ISO RGD PMID:23200123 RGD:7242632 NCBI chr11:25,954,352...26,024,919
Ensembl chr11:25,943,864...26,023,866 		JBrowse link
G KDM4A lysine demethylase 4A ISO RGD PMID:23200123 PMID:23642229 PMID:24035451 RGD:7242632 RGD:9479074 RGD:9479148 NCBI chr15:16,521,760...16,570,965
Ensembl chr15:16,521,700...16,571,000 		JBrowse link
G KDM4B lysine demethylase 4B ISO RGD PMID:23200123 RGD:7242632 NCBI chr20:54,713,900...54,843,991
Ensembl chr20:54,634,121...54,820,816 		JBrowse link
G KDM4C lysine demethylase 4C ISO RGD PMID:23200123 RGD:7242632 NCBI chr11:27,662,764...28,101,432
Ensembl chr11:27,693,536...28,101,801 		JBrowse link
G KDM5A lysine demethylase 5A ISO RGD PMID:23200123 RGD:7242632 NCBI chr27:42,364,606...42,447,839
Ensembl chr27:42,360,456...42,447,821 		JBrowse link
G KDM5B lysine demethylase 5B ISO RGD PMID:23200123 RGD:7242632 NCBI chr 7:336,452...415,568
Ensembl chr 7:330,705...412,386 		JBrowse link
G KDM5C lysine demethylase 5C ISO RGD PMID:23200123 RGD:7242632 NCBI chr  X:44,921,271...44,953,338
Ensembl chr  X:44,921,816...44,952,616 		JBrowse link
G KDM6A lysine demethylase 6A ISO RGD PMID:22663077 PMID:23200123 RGD:7242632 RGD:9479053 NCBI chr  X:38,745,854...38,964,029
Ensembl chr  X:38,745,854...38,959,842 		JBrowse link
G KDM6B lysine demethylase 6B ISO RGD PMID:23200123 RGD:7242632 NCBI chr 5:32,689,000...32,711,026
Ensembl chr 5:32,696,211...32,710,666 		JBrowse link
G KDM7A lysine demethylase 7A ISO RGD PMID:23200123 RGD:7242632 NCBI chr16:8,737,670...8,820,925
Ensembl chr16:8,740,492...8,814,402 		JBrowse link
G KDM8 lysine demethylase 8 ISO RGD PMID:23200123 RGD:7242632 NCBI chr 6:19,366,813...19,390,082
Ensembl chr 6:19,366,331...19,380,257 		JBrowse link
G KMT2A lysine methyltransferase 2A ISO RGD PMID:22663077 PMID:23200123 RGD:7242632 RGD:9479053 NCBI chr 5:15,212,559...15,302,825
Ensembl chr 5:15,217,348...15,270,971 		JBrowse link
G KMT2B lysine methyltransferase 2B ISO RGD PMID:22663077 PMID:23200123 RGD:7242632 RGD:9479053 NCBI chr 1:116,894,024...116,913,464
Ensembl chr 1:116,893,074...116,913,472 		JBrowse link
G KMT2C lysine methyltransferase 2C ISO RGD PMID:22663077 PMID:23200123 RGD:7242632 RGD:9479053 NCBI chr16:15,962,045...16,117,601
Ensembl chr16:15,963,901...16,158,408 		JBrowse link
G KMT2D lysine methyltransferase 2D ISO RGD PMID:22663077 PMID:23200123 RGD:7242632 RGD:9479053 NCBI chr27:5,516,866...5,556,303
Ensembl chr27:5,521,804...5,553,490 		JBrowse link
G KMT2E lysine methyltransferase 2E (inactive) ISO RGD PMID:23200123 RGD:7242632 NCBI chr18:15,240,631...15,332,850
Ensembl chr18:15,239,994...15,332,828 		JBrowse link
G KMT5B lysine methyltransferase 5B ISO RGD PMID:23200123 RGD:7242632 NCBI chr18:49,655,783...49,691,899
Ensembl chr18:49,637,610...49,827,034 		JBrowse link
G KMT5C lysine methyltransferase 5C ISO RGD PMID:23200123 RGD:7242632 NCBI chr 1:102,334,687...102,342,090
Ensembl chr 1:102,333,543...102,342,118 		JBrowse link
G L3MBTL1 L3MBTL histone methyl-lysine binding protein 1 ISO RGD PMID:23642229 RGD:9479074 NCBI chr24:31,238,787...31,266,062
Ensembl chr24:31,217,184...31,265,291 		JBrowse link
G LBR lamin B receptor ISO RGD PMID:24035451 RGD:9479148 NCBI chr 7:39,289,517...39,309,026
Ensembl chr 7:39,288,147...39,307,606 		JBrowse link
G LOC485121 lysine-specific demethylase 4D ISO RGD PMID:23200123 RGD:7242632 NCBI chr21:6,002,292...6,037,344
Ensembl chr21:5,987,723...6,004,783 		JBrowse link
G MACROH2A1 macroH2A.1 histone ISO RGD PMID:24696452 RGD:9074213 NCBI chr11:23,369,957...23,448,235
Ensembl chr11:23,370,300...23,438,219 		JBrowse link
G MACROH2A2 macroH2A.2 histone ISO RGD PMID:24696452 RGD:9074213 NCBI chr 4:21,057,935...21,087,097
Ensembl chr 4:21,057,947...21,086,730 		JBrowse link
G MCPH1 microcephalin 1 ISO RGD PMID:23642229 RGD:9479074 NCBI chr16:58,306,761...58,529,090
Ensembl chr16:58,295,280...58,529,433 		JBrowse link
G MDC1 mediator of DNA damage checkpoint 1 ISO RGD PMID:23642229 RGD:9479074 NCBI chr12:496,353...509,812
Ensembl chr12:496,878...507,442 		JBrowse link
G MEN1 menin 1 ISO RGD PMID:22663077 RGD:9479053 NCBI chr18:52,346,747...52,352,884
Ensembl chr18:52,346,933...52,353,340 		JBrowse link
G MYSM1 Myb like, SWIRM and MPN domains 1 ISO RGD PMID:24647359 RGD:9479061 NCBI chr 5:51,037,222...51,079,229
Ensembl chr 5:51,036,874...51,075,259 		JBrowse link
G NAP1L1 nucleosome assembly protein 1 like 1 ISO RGD PMID:23288364 RGD:9068945 NCBI chr15:19,141,803...19,175,576
Ensembl chr15:19,143,284...19,175,581 		JBrowse link
G NASP nuclear autoantigenic sperm protein ISO RGD PMID:23288364 RGD:9068945 NCBI chr15:14,742,008...14,782,186
Ensembl chr15:14,742,012...14,808,592 		JBrowse link
G NCOA6 nuclear receptor coactivator 6 ISO RGD PMID:22663077 RGD:9479053 NCBI chr24:23,802,360...23,877,986
Ensembl chr24:23,802,351...23,866,792 		JBrowse link
G NSD1 nuclear receptor binding SET domain protein 1 ISO RGD PMID:23200123 RGD:7242632 NCBI chr 4:36,058,351...36,214,254
Ensembl chr 4:36,063,134...36,210,999 		JBrowse link
G NSD3 nuclear receptor binding SET domain protein 3 ISO RGD PMID:23200123 RGD:7242632 NCBI chr16:27,106,348...27,225,049
Ensembl chr16:27,151,222...27,219,907 		JBrowse link
G ORC1 origin recognition complex subunit 1 ISO RGD PMID:23642229 RGD:9479074 NCBI chr15:8,965,339...8,995,527
Ensembl chr15:8,971,732...8,995,481 		JBrowse link
G PAGR1 PAXIP1 associated glutamate rich protein 1 ISO RGD PMID:22663077 RGD:9479053 NCBI chr 6:17,876,740...17,879,546 JBrowse link
G PAXIP1 PAX interacting protein 1 ISO RGD PMID:22663077 RGD:9479053 NCBI chr16:18,066,289...18,116,007
Ensembl chr16:18,066,246...18,112,506 		JBrowse link
G PBRM1 polybromo 1 ISO RGD PMID:24686119 RGD:9479075 NCBI chr20:37,110,437...37,231,676
Ensembl chr20:37,110,766...37,229,203 		JBrowse link
G PCGF1 polycomb group ring finger 1 ISO RGD PMID:23473600 PMID:25065329 RGD:9479058 RGD:9479060 NCBI chr17:48,633,207...48,642,435
Ensembl chr17:48,633,332...48,635,554 		JBrowse link
G PCGF2 polycomb group ring finger 2 ISO RGD PMID:23473600 PMID:25065329 RGD:9479058 RGD:9479060 NCBI chr 9:23,488,862...23,499,769
Ensembl chr 9:23,488,857...23,499,549 		JBrowse link
G PCGF3 polycomb group ring finger 3 ISO RGD PMID:23473600 PMID:25065329 RGD:9479058 RGD:9479060 NCBI chr 3:91,673,424...91,708,751
Ensembl chr 3:91,676,496...91,708,754 		JBrowse link
G PCGF5 polycomb group ring finger 5 ISO RGD PMID:23473600 PMID:25065329 RGD:9479058 RGD:9479060 NCBI chr28:5,821,278...5,889,382
Ensembl chr28:5,821,307...5,883,795 		JBrowse link
G PCGF6 polycomb group ring finger 6 ISO RGD PMID:23473600 PMID:25065329 RGD:9479058 RGD:9479060 NCBI chr28:15,697,707...15,733,177
Ensembl chr28:15,605,040...15,733,097 		JBrowse link
G PHC1 polyhomeotic homolog 1 ISO RGD PMID:23473600 PMID:25065329 RGD:9479058 RGD:9479060 NCBI chr27:36,797,327...36,816,726
Ensembl chr27:36,797,927...36,819,386 		JBrowse link
G PHC2 polyhomeotic homolog 2 ISO RGD PMID:23473600 PMID:25065329 RGD:9479058 RGD:9479060 NCBI chr 2:67,993,587...68,115,307
Ensembl chr 2:67,993,366...68,115,324 		JBrowse link
G PHC3 polyhomeotic homolog 3 ISO RGD PMID:23473600 PMID:25065329 RGD:9479058 RGD:9479060 NCBI chr34:34,651,828...34,739,613
Ensembl chr34:34,668,040...34,739,882 		JBrowse link
G PHF1 PHD finger protein 1 ISO RGD PMID:23642229 PMID:24035451 RGD:9479074 RGD:9479148 NCBI chr12:2,822,372...2,827,406
Ensembl chr12:2,822,295...2,827,413 		JBrowse link
G PHF19 PHD finger protein 19 ISO RGD PMID:23642229 PMID:24035451 RGD:9479074 RGD:9479148 NCBI chr11:73,895,104...73,911,030 JBrowse link
G PHF2 PHD finger protein 2 ISO RGD PMID:23200123 RGD:7242632 NCBI chr 1:98,188,014...98,253,930
Ensembl chr 1:98,188,826...98,254,411 		JBrowse link
G PHF8 PHD finger protein 8 ISO RGD PMID:23200123 RGD:7242632 NCBI chr  X:45,635,204...45,741,850
Ensembl chr  X:45,571,840...46,081,994 		JBrowse link
G PRDM16 PR/SET domain 16 ISO RGD PMID:23200123 RGD:7242632 NCBI chr 5:57,805,951...58,018,817
Ensembl chr 5:57,730,370...58,017,976 		JBrowse link
G PRDM2 PR/SET domain 2 ISO RGD PMID:23200123 RGD:7242632 NCBI chr 2:83,381,021...83,429,640
Ensembl chr 2:83,382,552...83,465,687 		JBrowse link
G PRDM6 PR/SET domain 6 ISO RGD PMID:23200123 RGD:7242632 NCBI chr11:12,942,789...13,046,278
Ensembl chr11:12,943,432...13,044,673 		JBrowse link
G PRDM8 PR/SET domain 8 ISO RGD PMID:23200123 RGD:7242632 NCBI chr32:4,435,693...4,451,500
Ensembl chr32:4,443,289...4,451,036 		JBrowse link
G PRMT1 protein arginine methyltransferase 1 ISO RGD PMID:24583552 RGD:9479047 NCBI chr 1:106,849,864...106,859,896
Ensembl chr 1:106,849,864...106,874,075 		JBrowse link
G PRMT2 protein arginine methyltransferase 2 ISO RGD PMID:24583552 RGD:9479047 NCBI chr31:39,806,086...39,838,959
Ensembl chr31:39,807,593...39,838,972 		JBrowse link
G PRMT5 protein arginine methyltransferase 5 ISO RGD PMID:24583552 RGD:9479047 NCBI chr 8:3,248,349...3,257,567
Ensembl chr 8:3,248,404...3,257,456 		JBrowse link
G PRMT6 protein arginine methyltransferase 6 ISO RGD PMID:24583552 RGD:9479047 NCBI chr 6:44,475,829...44,478,215
Ensembl chr 6:44,477,030...44,478,160 		JBrowse link
G PRMT7 protein arginine methyltransferase 7 ISO RGD PMID:24583552 RGD:9479047 NCBI chr 5:81,172,085...81,216,708
Ensembl chr 5:81,173,147...81,216,669 		JBrowse link
G RAG2 recombination activating 2 ISO RGD PMID:23642229 RGD:9479074 NCBI chr18:31,614,143...31,621,489
Ensembl chr18:31,618,481...31,620,064 		JBrowse link
G RBBP5 RB binding protein 5, histone lysine methyltransferase complex subunit ISO RGD PMID:22663077 RGD:9479053 NCBI chr38:1,606,751...1,646,444
Ensembl chr38:1,608,314...1,646,094 		JBrowse link
G RING1 ring finger protein 1 ISO RGD PMID:23473600 PMID:25065329 RGD:9479058 RGD:9479060 NCBI chr12:2,671,578...2,675,488
Ensembl chr12:2,671,578...2,675,488 		JBrowse link
G RNF2 ring finger protein 2 ISO RGD PMID:23473600 PMID:25065329 RGD:9479058 RGD:9479060 NCBI chr 7:18,240,672...18,283,091
Ensembl chr 7:18,236,115...18,281,387 		JBrowse link
G SETD1A SET domain containing 1A, histone lysine methyltransferase ISO RGD PMID:22663077 PMID:23200123 RGD:7242632 RGD:9479053 NCBI chr 6:17,224,107...17,246,527
Ensembl chr 6:17,224,694...17,245,870 		JBrowse link
G SETD1B SET domain containing 1B, histone lysine methyltransferase ISO RGD PMID:22663077 PMID:23200123 RGD:7242632 RGD:9479053 NCBI chr26:7,443,828...7,467,348
Ensembl chr26:7,446,267...7,467,429 		JBrowse link
G SETD2 SET domain containing 2, histone lysine methyltransferase ISO RGD PMID:23200123 RGD:7242632 NCBI chr20:41,675,539...41,800,697
Ensembl chr20:41,675,599...41,800,612 		JBrowse link
G SETD7 SET domain containing 7, histone lysine methyltransferase ISO RGD PMID:23200123 RGD:7242632 NCBI chr19:3,186,620...3,229,305
Ensembl chr19:3,186,906...3,224,113 		JBrowse link
G SETDB1 SET domain bifurcated histone lysine methyltransferase 1 ISO RGD PMID:23200123 RGD:7242632 NCBI chr17:60,035,819...60,069,721
Ensembl chr17:60,037,379...60,069,551 		JBrowse link
G SGF29 SAGA complex associated factor 29 ISO RGD PMID:23642229 PMID:24035451 RGD:9479074 RGD:9479148 NCBI chr 6:18,179,656...18,209,206
Ensembl chr 6:18,172,289...18,209,160 		JBrowse link
G SIRT1 sirtuin 1 ISO RGD PMID:21151613 RGD:9104959 NCBI chr 4:19,188,616...19,220,031
Ensembl chr 4:19,188,675...19,218,279 		JBrowse link
G SIRT2 sirtuin 2 ISO RGD PMID:21151613 RGD:9104959 NCBI chr 1:114,224,922...114,235,041
Ensembl chr 1:114,224,900...114,234,583 		JBrowse link
G SIRT3 sirtuin 3 ISO RGD PMID:21151613 RGD:9104959 NCBI chr18:25,369,183...25,388,126
Ensembl chr18:25,369,382...25,388,118 		JBrowse link
G SIRT4 sirtuin 4 ISO RGD PMID:21151613 RGD:9104959 NCBI chr26:16,228,831...16,244,104
Ensembl chr26:16,234,710...16,240,012 		JBrowse link
G SIRT5 sirtuin 5 ISO RGD PMID:21151613 RGD:9104959 NCBI chr35:13,017,397...13,055,655
Ensembl chr35:13,017,397...13,063,022 		JBrowse link
G SIRT6 sirtuin 6 ISO RGD PMID:21151613 RGD:9104959 NCBI chr20:55,412,989...55,424,944
Ensembl chr20:55,412,646...55,424,944 		JBrowse link
G SIRT7 sirtuin 7 ISO RGD PMID:21151613 RGD:9104959 NCBI chr 9:377,141...383,355
Ensembl chr 9:376,445...442,919 		JBrowse link
G SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 ISO RGD PMID:24686119 RGD:9479075 NCBI chr 1:90,709,221...90,884,295
Ensembl chr 1:90,712,520...90,883,622 		JBrowse link
G SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 ISO RGD PMID:24686119 RGD:9479075 NCBI chr20:50,175,489...50,268,865
Ensembl chr20:50,175,687...50,268,836 		JBrowse link
G SMYD1 SET and MYND domain containing 1 ISO RGD PMID:23200123 RGD:7242632 NCBI chr17:38,260,897...38,298,248
Ensembl chr17:38,259,624...38,298,183 		JBrowse link
G SMYD2 SET and MYND domain containing 2 ISO RGD PMID:23200123 RGD:7242632 NCBI chr 7:12,281,581...12,331,294
Ensembl chr 7:12,281,710...12,331,164 		JBrowse link
G SMYD3 SET and MYND domain containing 3 ISO RGD PMID:23200123 RGD:7242632 NCBI chr 7:36,561,080...37,250,336
Ensembl chr 7:36,565,901...37,250,578 		JBrowse link
G SPIN1 spindlin 1 ISO RGD PMID:24035451 RGD:9479148 NCBI chr 1:97,353,108...97,426,563
Ensembl chr 1:97,356,125...97,390,646 		JBrowse link
G SSRP1 structure specific recognition protein 1 ISO RGD PMID:23288364 RGD:9068945 NCBI chr18:38,802,673...38,812,134
Ensembl chr18:38,802,619...38,812,131 		JBrowse link
G SUPT16H SPT16 homolog, facilitates chromatin remodeling subunit ISO RGD PMID:23288364 RGD:9068945 NCBI chr15:18,387,624...18,429,553
Ensembl chr15:18,388,512...18,429,553 		JBrowse link
G SUV39H1 SUV39H1 histone lysine methyltransferase ISO RGD PMID:23200123 RGD:7242632 NCBI chr  X:41,894,623...41,907,854
Ensembl chr  X:41,893,045...41,906,403 		JBrowse link
G SUV39H2 SUV39H2 histone lysine methyltransferase ISO RGD PMID:23200123 RGD:7242632 NCBI chr 2:21,715,677...21,749,732
Ensembl chr 2:21,728,964...21,749,597 		JBrowse link
G TAF1 TATA-box binding protein associated factor 1 ISO RGD PMID:23642229 PMID:24686119 RGD:9479074 RGD:9479075 NCBI chr  X:55,693,091...55,764,268
Ensembl chr  X:55,693,194...55,763,683 		JBrowse link
G TDRD3 tudor domain containing 3 ISO RGD PMID:23211769 PMID:24035451 RGD:9479148 RGD:9479163 NCBI chr22:16,287,721...16,449,842
Ensembl chr22:16,288,473...16,444,635 		JBrowse link
G TP53BP1 tumor protein p53 binding protein 1 ISO RGD PMID:23642229 PMID:24035451 RGD:9479074 RGD:9479148 NCBI chr30:10,263,650...10,362,646
Ensembl chr30:10,263,650...10,336,134 		JBrowse link
G TRIM24 tripartite motif containing 24 ISO RGD PMID:23642229 RGD:9479074 NCBI chr16:10,033,993...10,133,450
Ensembl chr16:10,034,390...10,133,435 		JBrowse link
G TRIM33 tripartite motif containing 33 ISO RGD PMID:23642229 PMID:24686119 RGD:9479074 RGD:9479075 NCBI chr17:52,117,085...52,230,846
Ensembl chr17:52,118,476...52,230,530 		JBrowse link
G UHRF1 ubiquitin like with PHD and ring finger domains 1 ISO RGD PMID:23642229 PMID:24035451 RGD:9479074 RGD:9479148 NCBI chr20:54,858,673...54,889,769
Ensembl chr20:54,859,947...54,889,907 		JBrowse link
G USP12 ubiquitin specific peptidase 12 ISO RGD PMID:24647359 RGD:9479061 NCBI chr25:12,389,360...12,477,406
Ensembl chr25:12,338,673...12,474,362 		JBrowse link
G USP16 ubiquitin specific peptidase 16 ISO RGD PMID:24647359 RGD:9479061 NCBI chr31:24,034,399...24,060,268
Ensembl chr31:24,034,448...24,059,874 		JBrowse link
G USP21 ubiquitin specific peptidase 21 ISO RGD PMID:24647359 RGD:9479061 NCBI chr38:21,311,859...21,318,414
Ensembl chr38:21,311,859...21,320,106 		JBrowse link
G USP22 ubiquitin specific peptidase 22 ISO RGD PMID:24647359 RGD:9479061 NCBI chr 5:42,493,776...42,519,740
Ensembl chr 5:42,496,472...42,540,378 		JBrowse link
G USP3 ubiquitin specific peptidase 3 ISO RGD PMID:24647359 RGD:9479061 NCBI chr30:28,073,484...28,184,121
Ensembl chr30:28,072,655...28,181,749 		JBrowse link
G USP44 ubiquitin specific peptidase 44 ISO RGD PMID:24647359 RGD:9479061 NCBI chr15:35,401,486...35,454,351
Ensembl chr15:35,402,207...35,414,261 		JBrowse link
G WDR5 WD repeat domain 5 ISO RGD PMID:22663077 PMID:23642229 RGD:9479053 RGD:9479074 NCBI chr 9:50,352,600...50,371,224
Ensembl chr 9:50,352,472...50,371,236 		JBrowse link
G WDR82 WD repeat domain 82 ISO RGD PMID:22663077 RGD:9479053 NCBI chr20:37,494,633...37,513,746
Ensembl chr20:37,355,494...37,511,125 		JBrowse link
G YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta ISO RGD PMID:23642229 RGD:9479074 NCBI chr13:2,729,404...2,764,422 JBrowse link
homocysteine metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHCY adenosylhomocysteinase ISO RGD PMID:11741948 PMID:20814827 RGD:7242426 RGD:730275 NCBI chr24:23,410,553...23,423,494
Ensembl chr24:23,411,140...23,419,767 		JBrowse link
G AS3MT arsenite methyltransferase ISO RGD PMID:11790780 RGD:625365 NCBI chr28:15,334,141...15,350,749 JBrowse link
G CARM1 coactivator associated arginine methyltransferase 1 ISO RGD PMID:15866169 RGD:1359044 NCBI chr20:50,328,466...50,371,845
Ensembl chr20:50,331,030...50,348,195 		JBrowse link
G COMT catechol-O-methyltransferase ISO RGD PMID:12584150 RGD:1359089 NCBI chr26:29,359,930...29,381,854
Ensembl chr26:29,360,356...29,366,008 		JBrowse link
G DNMT1 DNA methyltransferase 1 ISO RGD PMID:12473678 RGD:1359078 NCBI chr20:50,872,213...50,928,352
Ensembl chr20:50,879,527...50,928,029 		JBrowse link
G GAMT guanidinoacetate N-methyltransferase ISO RGD PMID:15533043 RGD:1359081 NCBI chr20:57,440,698...57,442,588 JBrowse link
G GNMT glycine N-methyltransferase ISO RGD PMID:15347642 RGD:1359070 NCBI chr12:11,500,363...11,503,075
Ensembl chr12:11,500,392...11,503,481 		JBrowse link
G HNMT histamine N-methyltransferase ISO RGD PMID:11566133 RGD:1359041 NCBI chr19:40,656,266...40,702,498
Ensembl chr19:40,655,161...40,702,218 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase ISO RGD PMID:20814827 RGD:7242426 NCBI chr 2:84,445,526...84,457,435
Ensembl chr 2:84,380,919...84,536,818 		JBrowse link
G NNMT nicotinamide N-methyltransferase ISO RGD PMID:15922112 RGD:1359084 NCBI chr 5:19,026,514...19,044,154
Ensembl chr 5:19,026,556...19,044,016 		JBrowse link
G PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase ISO RGD PMID:8263531 RGD:729481 NCBI chr 1:40,494,441...40,539,453
Ensembl chr 1:40,494,461...40,538,937 		JBrowse link
G PEMT phosphatidylethanolamine N-methyltransferase ISO RGD PMID:8344945 RGD:729486 NCBI chr 5:41,871,685...41,960,831
Ensembl chr 5:41,872,108...41,960,828 		JBrowse link
G PNMT phenylethanolamine N-methyltransferase ISO RGD PMID:12438084 RGD:1359087 NCBI chr 9:22,808,505...22,810,587
Ensembl chr 9:22,808,601...22,810,551 		JBrowse link
G PRMT1 protein arginine methyltransferase 1 ISO RGD PMID:15866169 RGD:1359044 NCBI chr 1:106,849,864...106,859,896
Ensembl chr 1:106,849,864...106,874,075 		JBrowse link
G PRMT5 protein arginine methyltransferase 5 ISO RGD PMID:15866169 RGD:1359044 NCBI chr 8:3,248,349...3,257,567
Ensembl chr 8:3,248,404...3,257,456 		JBrowse link
G PRMT6 protein arginine methyltransferase 6 ISO RGD PMID:15866169 RGD:1359044 NCBI chr 6:44,475,829...44,478,215
Ensembl chr 6:44,477,030...44,478,160 		JBrowse link
G RNMT RNA guanine-7 methyltransferase ISO RGD PMID:11472630 RGD:1359071 NCBI chr 1:24,465,634...24,499,526
Ensembl chr 1:24,430,063...24,497,206 		JBrowse link
G SETDB1 SET domain bifurcated histone lysine methyltransferase 1 ISO RGD PMID:11959841 RGD:1359072 NCBI chr17:60,035,819...60,069,721
Ensembl chr17:60,037,379...60,069,551 		JBrowse link
methionine cycle/metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHCY adenosylhomocysteinase ISO SMPDB
RGD		 PMID:2292587 PMID:11741948 PMID:23073625 RGD:7242425 RGD:7242932 RGD:730275 SMP:00033 NCBI chr24:23,410,553...23,423,494
Ensembl chr24:23,411,140...23,419,767 		JBrowse link
G AMD1 adenosylmethionine decarboxylase 1 ISO SMPDB
RGD		 PMID:2292587 PMID:23073625 RGD:7242425 RGD:7242932 SMP:00033 NCBI chr12:67,432,871...67,453,791
Ensembl chr12:67,448,141...67,451,696 		JBrowse link
G AS3MT arsenite methyltransferase ISO RGD PMID:11790780 RGD:625365 NCBI chr28:15,334,141...15,350,749 JBrowse link
G ASMT acetylserotonin O-methyltransferase ISO RGD PMID:12198599 RGD:1359073 NCBI chr  X:1,012,952...1,025,684
Ensembl chr  X:1,012,961...1,025,263 		JBrowse link
G BHMT betaine--homocysteine S-methyltransferase ISO RGD
SMPDB		 PMID:15845641 PMID:23073625 RGD:1359026 RGD:7242425 SMP:00033 NCBI chr 3:27,732,381...27,752,168
Ensembl chr 3:27,734,108...27,752,046 		JBrowse link
G CARM1 coactivator associated arginine methyltransferase 1 ISO RGD PMID:15866169 PMID:21074527 RGD:1359044 RGD:7242552 NCBI chr20:50,328,466...50,371,845
Ensembl chr20:50,331,030...50,348,195 		JBrowse link
G CBS cystathionine beta-synthase ISO SMPDB SMP:00033 NCBI chr31:37,230,900...37,247,170 JBrowse link
G CHDH choline dehydrogenase ISO SMPDB SMP:00033 NCBI chr20:36,150,214...36,188,976
Ensembl chr20:36,150,229...36,187,068 		JBrowse link
G COMT catechol-O-methyltransferase ISO RGD PMID:12584150 RGD:1359089 NCBI chr26:29,359,930...29,381,854
Ensembl chr26:29,360,356...29,366,008 		JBrowse link
G CTH cystathionine gamma-lyase ISO SMPDB SMP:00033 NCBI chr 6:75,324,328...75,348,476
Ensembl chr 6:75,324,787...75,349,451 		JBrowse link
G DNMT1 DNA methyltransferase 1 ISO SMPDB
RGD		 PMID:12473678 PMID:22342103 RGD:1359078 RGD:7242551 SMP:00033 NCBI chr20:50,872,213...50,928,352
Ensembl chr20:50,879,527...50,928,029 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha ISO RGD PMID:22342103 RGD:7242551 NCBI chr17:19,489,524...19,563,074
Ensembl chr17:19,492,193...19,563,902 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta ISO RGD PMID:22342103 RGD:7242551 NCBI chr24:22,096,386...22,123,378
Ensembl chr24:22,096,349...22,122,900 		JBrowse link
G DOT1L DOT1 like histone lysine methyltransferase ISO RGD PMID:12628190 PMID:22194015 RGD:1359080 RGD:7242554 NCBI chr20:56,805,030...56,868,771
Ensembl chr20:56,803,242...56,852,539 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO RGD PMID:22194015 RGD:7242554 NCBI chr16:1,926,443...1,991,995
Ensembl chr16:1,925,956...1,991,838 		JBrowse link
G GAMT guanidinoacetate N-methyltransferase ISO RGD PMID:15533043 RGD:1359081 NCBI chr20:57,440,698...57,442,588 JBrowse link
G GNMT glycine N-methyltransferase ISO RGD PMID:15347642 PMID:22342103 PMID:23073625 RGD:1359070 RGD:7242425 RGD:7242551 NCBI chr12:11,500,363...11,503,075
Ensembl chr12:11,500,392...11,503,481 		JBrowse link
G HNMT histamine N-methyltransferase ISO RGD PMID:11566133 RGD:1359041 NCBI chr19:40,656,266...40,702,498
Ensembl chr19:40,655,161...40,702,218 		JBrowse link
G IL4I1 interleukin 4 induced 1 ISO SMPDB SMP:00033 NCBI chr 1:106,636,282...106,673,438
Ensembl chr 1:106,657,477...106,673,422 		JBrowse link
G MARS1 methionyl-tRNA synthetase 1 ISO SMPDB SMP:00033 NCBI chr10:1,588,503...1,606,752
Ensembl chr10:1,588,875...1,606,750 		JBrowse link
G MAT1A methionine adenosyltransferase 1A ISO RGD PMID:2292587 PMID:9202427 PMID:23073625 RGD:1359039 RGD:7242425 RGD:7242932 NCBI chr 4:29,450,857...29,467,251
Ensembl chr 4:29,452,601...29,466,929 		JBrowse link
G MAT2A methionine adenosyltransferase 2A ISO SMPDB
RGD		 PMID:11099469 PMID:23073625 RGD:1359040 RGD:7242425 SMP:00033 NCBI chr17:39,525,635...39,532,512
Ensembl chr17:39,525,626...39,532,512 		JBrowse link
G MAT2B methionine adenosyltransferase 2B ISO SMPDB
RGD		 PMID:23073625 RGD:7242425 SMP:00033 NCBI chr 4:47,703,991...47,726,363
Ensembl chr 4:47,709,576...47,726,360 		JBrowse link
G MRM2 mitochondrial rRNA methyltransferase 2 ISO RGD PMID:11827451 RGD:1359074 NCBI chr 6:14,881,522...14,887,741
Ensembl chr 6:14,881,539...14,887,133 		JBrowse link
G MSRB2 methionine sulfoxide reductase B2 ISO SMPDB SMP:00033 NCBI chr 2:10,134,747...10,152,830
Ensembl chr 2:10,135,112...10,152,836 		JBrowse link
G MSRB3 methionine sulfoxide reductase B3 ISO SMPDB SMP:00033 NCBI chr10:7,892,745...8,040,196
Ensembl chr10:7,892,640...8,038,043 		JBrowse link
G MTAP methylthioadenosine phosphorylase ISO SMPDB
RGD		 PMID:2292587 RGD:7242932 SMP:00033 NCBI chr11:41,148,389...41,200,635
Ensembl chr11:41,148,404...41,264,504 		JBrowse link
G MTFMT mitochondrial methionyl-tRNA formyltransferase ISO SMPDB SMP:00033 NCBI chr30:29,388,600...29,415,578
Ensembl chr30:29,388,649...29,450,430 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase ISO SMPDB
RGD		 PMID:11933257 RGD:1535021 SMP:00033 NCBI chr 2:84,445,526...84,457,435
Ensembl chr 2:84,380,919...84,536,818 		JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase ISO SMPDB
RGD		 PMID:15845641 PMID:20814827 PMID:23073625 RGD:1359026 RGD:7242425 RGD:7242426 SMP:00033 NCBI chr 4:3,219,851...3,328,000
Ensembl chr 4:3,215,090...3,328,115 		JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase ISO RGD PMID:15979034 PMID:20814827 RGD:1359037 RGD:7242426 NCBI chr34:6,068,572...6,119,580
Ensembl chr34:6,070,046...6,098,312 		JBrowse link
G NNMT nicotinamide N-methyltransferase ISO RGD PMID:15922112 RGD:1359084 NCBI chr 5:19,026,514...19,044,154
Ensembl chr 5:19,026,556...19,044,016 		JBrowse link
G PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase ISO RGD PMID:8263531 RGD:729481 NCBI chr 1:40,494,441...40,539,453
Ensembl chr 1:40,494,461...40,538,937 		JBrowse link
G PEMT phosphatidylethanolamine N-methyltransferase ISO RGD PMID:8344945 RGD:729486 NCBI chr 5:41,871,685...41,960,831
Ensembl chr 5:41,872,108...41,960,828 		JBrowse link
G PNMT phenylethanolamine N-methyltransferase ISO RGD PMID:12438084 RGD:1359087 NCBI chr 9:22,808,505...22,810,587
Ensembl chr 9:22,808,601...22,810,551 		JBrowse link
G PRMT1 protein arginine methyltransferase 1 ISO RGD PMID:15866169 PMID:21074527 RGD:1359044 RGD:7242552 NCBI chr 1:106,849,864...106,859,896
Ensembl chr 1:106,849,864...106,874,075 		JBrowse link
G PRMT2 protein arginine methyltransferase 2 ISO RGD PMID:21074527 RGD:7242552 NCBI chr31:39,806,086...39,838,959
Ensembl chr31:39,807,593...39,838,972 		JBrowse link
G PRMT3 protein arginine methyltransferase 3 ISO RGD PMID:21074527 RGD:7242552 NCBI chr21:42,406,327...42,530,157
Ensembl chr21:42,406,314...42,528,116 		JBrowse link
G PRMT5 protein arginine methyltransferase 5 ISO RGD PMID:15866169 PMID:21074527 RGD:1359044 RGD:7242552 NCBI chr 8:3,248,349...3,257,567
Ensembl chr 8:3,248,404...3,257,456 		JBrowse link
G PRMT6 protein arginine methyltransferase 6 ISO RGD PMID:15866169 PMID:21074527 RGD:1359044 RGD:7242552 NCBI chr 6:44,475,829...44,478,215
Ensembl chr 6:44,477,030...44,478,160 		JBrowse link
G PRMT7 protein arginine methyltransferase 7 ISO RGD PMID:21074527 RGD:7242552 NCBI chr 5:81,172,085...81,216,708
Ensembl chr 5:81,173,147...81,216,669 		JBrowse link
G RNMT RNA guanine-7 methyltransferase ISO RGD PMID:11472630 RGD:1359071 NCBI chr 1:24,465,634...24,499,526
Ensembl chr 1:24,430,063...24,497,206 		JBrowse link
G SETD7 SET domain containing 7, histone lysine methyltransferase ISO RGD PMID:22194015 RGD:7242554 NCBI chr19:3,186,620...3,229,305
Ensembl chr19:3,186,906...3,224,113 		JBrowse link
G SETDB1 SET domain bifurcated histone lysine methyltransferase 1 ISO RGD PMID:11959841 RGD:1359072 NCBI chr17:60,035,819...60,069,721
Ensembl chr17:60,037,379...60,069,551 		JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 ISO SMPDB SMP:00033 NCBI chr 5:41,221,531...41,248,653
Ensembl chr 5:41,221,562...41,253,166 		JBrowse link
G SMS spermine synthase ISO RGD PMID:23073625 RGD:7242425 NCBI chr  X:17,749,020...17,803,351
Ensembl chr  X:17,749,530...17,802,999 		JBrowse link
G SMYD2 SET and MYND domain containing 2 ISO RGD PMID:22194015 RGD:7242554 NCBI chr 7:12,281,581...12,331,294
Ensembl chr 7:12,281,710...12,331,164 		JBrowse link
G SRM spermidine synthase ISO SMPDB
RGD		 PMID:23073625 RGD:7242425 SMP:00033 NCBI chr 2:84,968,833...84,973,111
Ensembl chr 2:84,967,570...84,973,087 		JBrowse link
G SUV39H1 SUV39H1 histone lysine methyltransferase ISO RGD PMID:22194015 RGD:7242554 NCBI chr  X:41,894,623...41,907,854
Ensembl chr  X:41,893,045...41,906,403 		JBrowse link
G SUV39H2 SUV39H2 histone lysine methyltransferase ISO RGD PMID:22194015 RGD:7242554 NCBI chr 2:21,715,677...21,749,732
Ensembl chr 2:21,728,964...21,749,597 		JBrowse link
polyamine metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMD1 adenosylmethionine decarboxylase 1 ISO RGD PMID:10430362 PMID:13678416 RGD:1578320 RGD:7244193 NCBI chr12:67,432,871...67,453,791
Ensembl chr12:67,448,141...67,451,696 		JBrowse link
G AZIN1 antizyme inhibitor 1 ISO RGD PMID:21849468 RGD:7244195 NCBI chr13:4,363,996...4,396,069
Ensembl chr13:4,361,340...4,396,040 		JBrowse link
G OAZ1 ornithine decarboxylase antizyme 1 ISO RGD PMID:21849468 RGD:7244195 NCBI chr20:56,769,317...56,770,921
Ensembl chr20:56,769,319...56,770,930 		JBrowse link
G OAZ2 ornithine decarboxylase antizyme 2 ISO RGD PMID:21849468 RGD:7244195 NCBI chr30:29,122,556...29,126,513
Ensembl chr30:29,122,556...29,126,512 		JBrowse link
G OAZ3 ornithine decarboxylase antizyme 3 ISO RGD PMID:21849468 RGD:7244195 NCBI chr17:60,789,541...60,792,954
Ensembl chr17:60,786,963...60,792,954 		JBrowse link
G ODC1 ornithine decarboxylase 1 ISO RGD PMID:10430362 PMID:13678416 RGD:1578320 RGD:7244193 NCBI chr17:7,368,699...7,376,970
Ensembl chr17:7,369,232...7,376,975 		JBrowse link
G PAOX polyamine oxidase ISO RGD PMID:13678416 PMID:15541750 RGD:7244190 RGD:7244193
G SAT1 spermidine/spermine N1-acetyltransferase 1 ISO RGD PMID:13678416 PMID:15541750 RGD:7244190 RGD:7244193 NCBI chr  X:19,461,945...19,464,209
Ensembl chr  X:19,463,109...19,464,116 		JBrowse link
G SMOX spermine oxidase ISO RGD PMID:13678416 PMID:15541750 RGD:7244190 RGD:7244193 NCBI chr24:17,240,910...17,291,258
Ensembl chr24:17,252,537...17,300,451 		JBrowse link
G SMS spermine synthase ISO RGD PMID:13678416 RGD:7244193 NCBI chr  X:17,749,020...17,803,351
Ensembl chr  X:17,749,530...17,802,999 		JBrowse link
G SRM spermidine synthase ISO RGD PMID:13678416 RGD:7244193 NCBI chr 2:84,968,833...84,973,111
Ensembl chr 2:84,967,570...84,973,087 		JBrowse link
putrescine metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMD1 adenosylmethionine decarboxylase 1 ISO RGD PMID:10430362 RGD:1578320 NCBI chr12:67,432,871...67,453,791
Ensembl chr12:67,448,141...67,451,696 		JBrowse link
G ODC1 ornithine decarboxylase 1 ISO RGD PMID:10430362 RGD:1578320 NCBI chr17:7,368,699...7,376,970
Ensembl chr17:7,369,232...7,376,975 		JBrowse link
remethylation pathway of homocysteine metabolism - cobalamin dependent term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MTHFR methylenetetrahydrofolate reductase ISO RGD PMID:20814827 RGD:7242426 NCBI chr 2:84,445,526...84,457,435
Ensembl chr 2:84,380,919...84,536,818 		JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase ISO RGD PMID:15845641 PMID:20814827 RGD:1359026 RGD:7242426 NCBI chr 4:3,219,851...3,328,000
Ensembl chr 4:3,215,090...3,328,115 		JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase ISO RGD PMID:15979034 PMID:20814827 RGD:1359037 RGD:7242426 NCBI chr34:6,068,572...6,119,580
Ensembl chr34:6,070,046...6,098,312 		JBrowse link
remethylation pathway of homocysteine metabolism - cobalamin independent, betaine dependent term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHCY adenosylhomocysteinase ISO SMPDB SMP:00123 NCBI chr24:23,410,553...23,423,494
Ensembl chr24:23,411,140...23,419,767 		JBrowse link
G ALDH7A1 aldehyde dehydrogenase 7 family member A1 ISO SMPDB SMP:00123 NCBI chr11:15,828,581...15,878,556
Ensembl chr11:15,815,936...15,878,516 		JBrowse link
G BHMT betaine--homocysteine S-methyltransferase ISO SMPDB
RGD		 PMID:15845641 PMID:20346934 PMID:20814827 RGD:1359026 RGD:7242426 RGD:7242428 SMP:00123 NCBI chr 3:27,732,381...27,752,168
Ensembl chr 3:27,734,108...27,752,046 		JBrowse link
G CHDH choline dehydrogenase ISO SMPDB SMP:00123 NCBI chr20:36,150,214...36,188,976
Ensembl chr20:36,150,229...36,187,068 		JBrowse link
G MAT2A methionine adenosyltransferase 2A ISO SMPDB SMP:00123 NCBI chr17:39,525,635...39,532,512
Ensembl chr17:39,525,626...39,532,512 		JBrowse link
G MAT2B methionine adenosyltransferase 2B ISO SMPDB SMP:00123 NCBI chr 4:47,703,991...47,726,363
Ensembl chr 4:47,709,576...47,726,360 		JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase ISO SMPDB SMP:00123 NCBI chr 4:3,219,851...3,328,000
Ensembl chr 4:3,215,090...3,328,115 		JBrowse link
G PEMT phosphatidylethanolamine N-methyltransferase ISO SMPDB SMP:00123 NCBI chr 5:41,871,685...41,960,831
Ensembl chr 5:41,872,108...41,960,828 		JBrowse link
spermidine metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMD1 adenosylmethionine decarboxylase 1 ISO RGD
SMPDB		 PMID:1415709 PMID:10430362 PMID:10712236 RGD:1578320 RGD:7242911 RGD:7242912 SMP:00445 NCBI chr12:67,432,871...67,453,791
Ensembl chr12:67,448,141...67,451,696 		JBrowse link
G MAT2A methionine adenosyltransferase 2A ISO SMPDB SMP:00445 NCBI chr17:39,525,635...39,532,512
Ensembl chr17:39,525,626...39,532,512 		JBrowse link
G MAT2B methionine adenosyltransferase 2B ISO SMPDB SMP:00445 NCBI chr 4:47,703,991...47,726,363
Ensembl chr 4:47,709,576...47,726,360 		JBrowse link
G ODC1 ornithine decarboxylase 1 ISO RGD
SMPDB		 PMID:1415709 PMID:2292587 PMID:10430362 RGD:1578320 RGD:7242912 RGD:7242932 SMP:00445 NCBI chr17:7,368,699...7,376,970
Ensembl chr17:7,369,232...7,376,975 		JBrowse link
G SAT1 spermidine/spermine N1-acetyltransferase 1 ISO RGD PMID:2292587 RGD:7242932 NCBI chr  X:19,461,945...19,464,209
Ensembl chr  X:19,463,109...19,464,116 		JBrowse link
G SMS spermine synthase ISO SMPDB SMP:00445 NCBI chr  X:17,749,020...17,803,351
Ensembl chr  X:17,749,530...17,802,999 		JBrowse link
G SRM spermidine synthase ISO SMPDB
RGD		 PMID:2292587 PMID:16931179 PMID:23073625 RGD:7242425 RGD:7242920 RGD:7242932 SMP:00445 NCBI chr 2:84,968,833...84,973,111
Ensembl chr 2:84,967,570...84,973,087 		JBrowse link
spermine metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMD1 adenosylmethionine decarboxylase 1 ISO RGD
SMPDB		 PMID:1415709 PMID:10430362 PMID:10712236 RGD:1578320 RGD:7242911 RGD:7242912 SMP:00445 NCBI chr12:67,432,871...67,453,791
Ensembl chr12:67,448,141...67,451,696 		JBrowse link
G MAT2A methionine adenosyltransferase 2A ISO SMPDB SMP:00445 NCBI chr17:39,525,635...39,532,512
Ensembl chr17:39,525,626...39,532,512 		JBrowse link
G MAT2B methionine adenosyltransferase 2B ISO SMPDB SMP:00445 NCBI chr 4:47,703,991...47,726,363
Ensembl chr 4:47,709,576...47,726,360 		JBrowse link
G ODC1 ornithine decarboxylase 1 ISO RGD
SMPDB		 PMID:1415709 PMID:2292587 PMID:10430362 RGD:1578320 RGD:7242912 RGD:7242932 SMP:00445 NCBI chr17:7,368,699...7,376,970
Ensembl chr17:7,369,232...7,376,975 		JBrowse link
G SAT1 spermidine/spermine N1-acetyltransferase 1 ISO RGD PMID:2292587 RGD:7242932 NCBI chr  X:19,461,945...19,464,209
Ensembl chr  X:19,463,109...19,464,116 		JBrowse link
G SMS spermine synthase ISO SMPDB
RGD		 PMID:2292587 PMID:23073625 RGD:7242425 RGD:7242932 SMP:00445 NCBI chr  X:17,749,020...17,803,351
Ensembl chr  X:17,749,530...17,802,999 		JBrowse link
G SRM spermidine synthase ISO SMPDB SMP:00445 NCBI chr 2:84,968,833...84,973,111
Ensembl chr 2:84,967,570...84,973,087 		JBrowse link
transsulfuration pathway of homocysteine metabolism term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBS cystathionine beta-synthase ISO SMPDB
RGD		 PMID:20162368 RGD:7242427 SMP:00455 NCBI chr31:37,230,900...37,247,170 JBrowse link
G CDO1 cysteine dioxygenase type 1 ISO RGD PMID:20162368 RGD:7242427 NCBI chr11:5,512,996...5,524,556
Ensembl chr11:5,371,378...5,524,562 		JBrowse link
G CSAD cysteine sulfinic acid decarboxylase ISO RGD PMID:20162368 RGD:7242427 NCBI chr27:2,005,482...2,036,703
Ensembl chr27:2,005,355...2,036,228 		JBrowse link
G CTH cystathionine gamma-lyase ISO SMPDB
RGD		 PMID:20162368 RGD:7242427 SMP:00455 NCBI chr 6:75,324,328...75,348,476
Ensembl chr 6:75,324,787...75,349,451 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4046
    regulatory pathway 2499
      homeostasis pathway 1305
        organic chemical homeostasis pathway 363
          S-adenosylmethionine homeostasis pathway 262
            DNA modification pathway + 28
            folate metabolic pathway + 32
            histone modification pathway + 169
            homocysteine metabolic pathway + 29
            methionine cycle/metabolic pathway + 50
            polyamine metabolic pathway + 13
            radical SAM enzyme mediated metabolic pathway + 0
paths to the root