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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:sarcosinemia pathway
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Accession:PW:0001670 term browser browse the term
Definition:A rare autosomal recessive metabolic disorder due to mutations in sarcosine dehydrogenase resulting in alterations of sarcosine metabolism.
Synonyms:exact_synonym: SARCOS pathway;   SARD deficiency pathway;   SARDH deficiency pathway;   SARDHD pathway;   hypersarcosinemia pathway;   sarcosine dehydrogenase complex deficiency pathway;   sarcosinemia disease pathway
 related_synonym: SMP:00244


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sarcosinemia pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGXT alanine--glyoxylate aminotransferase ISO SMPDB SMP:00244 NCBI chr15:139,720,648...139,730,737
Ensembl chr15:139,720,612...139,730,736 		JBrowse link
G ALAS1 aminolevulinate, delta-, synthase 1 pseudogene ISO SMPDB SMP:00244 NCBI chr13:34,333,263...34,347,435
Ensembl chr13:34,333,113...34,347,589 		JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member ISO SMPDB SMP:00244 NCBI chr14:39,902,317...39,933,113
Ensembl chr14:39,896,565...39,933,124 		JBrowse link
G AMT aminomethyltransferase ISO SMPDB SMP:00244 NCBI chr13:31,995,600...32,002,514
Ensembl chr13:31,995,595...32,002,470 		JBrowse link
G BHMT betaine--homocysteine S-methyltransferase ISO SMPDB SMP:00244 NCBI chr 2:87,911,093...87,935,252
Ensembl chr 2:87,910,603...87,935,252 		JBrowse link
G CBS cystathionine beta-synthase ISO SMPDB SMP:00244 NCBI chr13:206,205,942...206,231,363
Ensembl chr13:206,205,946...206,230,248 		JBrowse link
G CTH cystathionine gamma-lyase ISO SMPDB SMP:00244 NCBI chr 6:142,454,922...142,486,352
Ensembl chr 6:142,454,914...142,486,367 		JBrowse link
G DLD dihydrolipoamide dehydrogenase ISO SMPDB SMP:00244 NCBI chr 9:107,642,129...107,668,443
Ensembl chr 9:107,642,095...107,673,583 		JBrowse link
G DMGDH dimethylglycine dehydrogenase ISO SMPDB SMP:00244 NCBI chr 2:87,791,827...87,867,189
Ensembl chr 2:87,791,943...87,866,679 		JBrowse link
G GAMT guanidinoacetate N-methyltransferase ISO SMPDB SMP:00244 NCBI chr 2:77,076,566...77,079,751
Ensembl chr 2:77,076,566...77,079,759 		JBrowse link
G GARS1 glycyl-tRNA synthetase 1 ISO SMPDB SMP:00244 NCBI chr18:42,311,711...42,352,201
Ensembl chr18:42,311,576...42,352,162 		JBrowse link
G GATM glycine amidinotransferase ISO SMPDB SMP:00244 NCBI chr 1:126,361,968...126,378,705
Ensembl chr 1:126,361,945...126,380,871 		JBrowse link
G GCAT glycine C-acetyltransferase ISO SMPDB SMP:00244 NCBI chr 5:10,027,133...10,038,494
Ensembl chr 5:10,027,044...10,038,433 		JBrowse link
G GLDC glycine decarboxylase ISO SMPDB SMP:00244 NCBI chr 1:215,608,854...215,715,062
Ensembl chr 1:215,608,849...215,715,059 		JBrowse link
G GLYCTK glycerate kinase ISO SMPDB SMP:00244 NCBI chr13:34,433,403...34,440,037
Ensembl chr13:34,433,399...34,440,264 		JBrowse link
G GNMT glycine N-methyltransferase ISO SMPDB SMP:00244 NCBI chr 7:38,038,359...38,041,218
Ensembl chr 7:38,038,358...38,041,217 		JBrowse link
G MAOA monoamine oxidase A ISO SMPDB SMP:00244 NCBI chr  X:38,930,452...39,006,220 JBrowse link
G PHGDH phosphoglycerate dehydrogenase ISO SMPDB SMP:00244 NCBI chr 4:101,445,977...101,478,144
Ensembl chr 4:101,444,693...101,478,144 		JBrowse link
G PSAT1 phosphoserine aminotransferase 1 ISO SMPDB SMP:00244 NCBI chr 1:231,142,673...231,172,364
Ensembl chr 1:231,142,625...231,172,360 		JBrowse link
G PSPH phosphoserine phosphatase ISO SMPDB SMP:00244 NCBI chr 3:16,877,904...16,903,062
Ensembl chr 3:16,877,923...16,907,952 		JBrowse link
G SARDH sarcosine dehydrogenase ISO SMPDB SMP:00244 NCBI chr 1:273,230,357...273,295,170
Ensembl chr 1:273,230,375...273,294,621 		JBrowse link
G SARS1 seryl-tRNA synthetase 1 ISO SMPDB SMP:00244 NCBI chr 4:110,857,067...110,874,712
Ensembl chr 4:110,857,089...110,874,815 		JBrowse link
G SDS serine dehydratase ISO SMPDB SMP:00244 NCBI chr14:38,503,922...38,513,908
Ensembl chr14:38,503,933...38,513,878 		JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 ISO SMPDB SMP:00244 NCBI chr12:60,414,421...60,435,451
Ensembl chr12:60,416,463...60,435,450 		JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 ISO SMPDB SMP:00244 NCBI chr 5:22,535,780...22,540,322
Ensembl chr 5:22,532,894...22,540,319 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4047
    disease pathway 712
      nutritional and metabolic disease pathway 574
        metabolic disease pathway 535
          mitochondrial disease pathway 81
            sarcosinemia pathway 25
Path 2
Term Annotations click to browse term
  pathway 4047
    disease pathway 712
      nutritional and metabolic disease pathway 574
        metabolic disease pathway 535
          inborn error of metabolism pathway 518
            inborn error of amino acid metabolism pathway 226
              sarcosinemia pathway 25
paths to the root