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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:antihemorrhagic drug pathway
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Accession:PW:0001652 term browser browse the term
Definition:The pharmacokinetics and pharmacodynamics pathway of drugs that reduce or prevent bleeding. It is to be noted here that genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: hemostatic drug pathway

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aminocaproic acid pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00286 NCBI chrNW_004936490:11,448,552...11,465,836
Ensembl chrNW_004936490:11,448,654...11,464,444 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00286 NCBI chrNW_004936472:475,851...502,341
Ensembl chrNW_004936472:475,333...502,377 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00286 NCBI chrNW_004936597:1,687,511...1,694,782 JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00286 NCBI chrNW_004936534:6,199,066...6,360,374
Ensembl chrNW_004936534:6,199,066...6,361,476 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00286 NCBI chrNW_004936567:6,712,666...6,735,539 JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00286 NCBI chrNW_004936562:2,371,725...2,388,617
Ensembl chrNW_004936562:2,372,044...2,388,650 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00286 NCBI chrNW_004936537:4,637,028...4,647,915
Ensembl chrNW_004936537:4,636,667...4,647,916 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00286 NCBI chrNW_004936481:17,114,441...17,178,902
Ensembl chrNW_004936481:17,114,480...17,178,844 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00286 NCBI chrNW_004936472:505,751...515,375
Ensembl chrNW_004936472:505,751...514,339 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00286 NCBI chrNW_004936927:189,359...301,791
Ensembl chrNW_004936927:190,111...301,609 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00286 NCBI chrNW_004936513:8,052,998...8,090,245
Ensembl chrNW_004936513:8,053,615...8,090,234 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00286 NCBI chrNW_004936576:1,322,406...1,329,743 JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00286 NCBI chrNW_004936576:1,306,076...1,313,485
Ensembl chrNW_004936576:1,306,109...1,313,386 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00286 NCBI chrNW_004936576:1,343,657...1,352,085
Ensembl chrNW_004936576:1,343,661...1,352,143 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00286 NCBI chrNW_004936712:1,696,264...1,709,087
Ensembl chrNW_004936712:1,699,750...1,709,087 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00286 NCBI chrNW_004936554:3,227,395...3,256,710
Ensembl chrNW_004936554:3,228,735...3,256,710 		JBrowse link
G LOC101967202 coagulation factor XI ISO SMPDB SMP:00286 NCBI chrNW_004936554:3,205,539...3,223,228
Ensembl chrNW_004936554:3,205,539...3,219,311 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00286 NCBI chrNW_004936785:476,200...503,371
Ensembl chrNW_004936785:476,078...503,321 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00286 NCBI chrNW_004936489:11,775,243...11,808,482
Ensembl chrNW_004936489:11,775,243...11,805,651 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00286 NCBI chrNW_004936501:13,459,400...13,461,864
Ensembl chrNW_004936501:13,459,022...13,462,174 		JBrowse link
aprotinin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00288 NCBI chrNW_004936490:11,448,552...11,465,836
Ensembl chrNW_004936490:11,448,654...11,464,444 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00288 NCBI chrNW_004936472:475,851...502,341
Ensembl chrNW_004936472:475,333...502,377 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00288 NCBI chrNW_004936597:1,687,511...1,694,782 JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00288 NCBI chrNW_004936534:6,199,066...6,360,374
Ensembl chrNW_004936534:6,199,066...6,361,476 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00288 NCBI chrNW_004936567:6,712,666...6,735,539 JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00288 NCBI chrNW_004936562:2,371,725...2,388,617
Ensembl chrNW_004936562:2,372,044...2,388,650 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00288 NCBI chrNW_004936537:4,637,028...4,647,915
Ensembl chrNW_004936537:4,636,667...4,647,916 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00288 NCBI chrNW_004936481:17,114,441...17,178,902
Ensembl chrNW_004936481:17,114,480...17,178,844 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00288 NCBI chrNW_004936472:505,751...515,375
Ensembl chrNW_004936472:505,751...514,339 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00288 NCBI chrNW_004936927:189,359...301,791
Ensembl chrNW_004936927:190,111...301,609 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00288 NCBI chrNW_004936513:8,052,998...8,090,245
Ensembl chrNW_004936513:8,053,615...8,090,234 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00288 NCBI chrNW_004936576:1,322,406...1,329,743 JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00288 NCBI chrNW_004936576:1,306,076...1,313,485
Ensembl chrNW_004936576:1,306,109...1,313,386 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00288 NCBI chrNW_004936576:1,343,657...1,352,085
Ensembl chrNW_004936576:1,343,661...1,352,143 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00288 NCBI chrNW_004936712:1,696,264...1,709,087
Ensembl chrNW_004936712:1,699,750...1,709,087 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00288 NCBI chrNW_004936554:3,227,395...3,256,710
Ensembl chrNW_004936554:3,228,735...3,256,710 		JBrowse link
G LOC101967202 coagulation factor XI ISO SMPDB SMP:00288 NCBI chrNW_004936554:3,205,539...3,223,228
Ensembl chrNW_004936554:3,205,539...3,219,311 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00288 NCBI chrNW_004936785:476,200...503,371
Ensembl chrNW_004936785:476,078...503,321 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00288 NCBI chrNW_004936489:11,775,243...11,808,482
Ensembl chrNW_004936489:11,775,243...11,805,651 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00288 NCBI chrNW_004936501:13,459,400...13,461,864
Ensembl chrNW_004936501:13,459,022...13,462,174 		JBrowse link
tranexamic acid pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00287 NCBI chrNW_004936490:11,448,552...11,465,836
Ensembl chrNW_004936490:11,448,654...11,464,444 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00287 NCBI chrNW_004936472:475,851...502,341
Ensembl chrNW_004936472:475,333...502,377 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00287 NCBI chrNW_004936597:1,687,511...1,694,782 JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00287 NCBI chrNW_004936534:6,199,066...6,360,374
Ensembl chrNW_004936534:6,199,066...6,361,476 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00287 NCBI chrNW_004936567:6,712,666...6,735,539 JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00287 NCBI chrNW_004936562:2,371,725...2,388,617
Ensembl chrNW_004936562:2,372,044...2,388,650 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00287 NCBI chrNW_004936537:4,637,028...4,647,915
Ensembl chrNW_004936537:4,636,667...4,647,916 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00287 NCBI chrNW_004936481:17,114,441...17,178,902
Ensembl chrNW_004936481:17,114,480...17,178,844 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00287 NCBI chrNW_004936472:505,751...515,375
Ensembl chrNW_004936472:505,751...514,339 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00287 NCBI chrNW_004936927:189,359...301,791
Ensembl chrNW_004936927:190,111...301,609 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00287 NCBI chrNW_004936513:8,052,998...8,090,245
Ensembl chrNW_004936513:8,053,615...8,090,234 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00287 NCBI chrNW_004936576:1,322,406...1,329,743 JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00287 NCBI chrNW_004936576:1,306,076...1,313,485
Ensembl chrNW_004936576:1,306,109...1,313,386 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00287 NCBI chrNW_004936576:1,343,657...1,352,085
Ensembl chrNW_004936576:1,343,661...1,352,143 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00287 NCBI chrNW_004936712:1,696,264...1,709,087
Ensembl chrNW_004936712:1,699,750...1,709,087 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00287 NCBI chrNW_004936554:3,227,395...3,256,710
Ensembl chrNW_004936554:3,228,735...3,256,710 		JBrowse link
G LOC101967202 coagulation factor XI ISO SMPDB SMP:00287 NCBI chrNW_004936554:3,205,539...3,223,228
Ensembl chrNW_004936554:3,205,539...3,219,311 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00287 NCBI chrNW_004936785:476,200...503,371
Ensembl chrNW_004936785:476,078...503,321 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00287 NCBI chrNW_004936489:11,775,243...11,808,482
Ensembl chrNW_004936489:11,775,243...11,805,651 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00287 NCBI chrNW_004936501:13,459,400...13,461,864
Ensembl chrNW_004936501:13,459,022...13,462,174 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 3945
    drug pathway 362
      blood and blood forming organs drug pathway 49
        antihemorrhagic drug pathway 20
          aminocaproic acid drug pathway + 20
          aprotinin drug pathway + 20
          tranexamic acid drug pathway + 20
paths to the root