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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:antihemorrhagic drug pathway
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Accession:PW:0001652 term browser browse the term
Definition:The pharmacokinetics and pharmacodynamics pathway of drugs that reduce or prevent bleeding. It is to be noted here that genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: hemostatic drug pathway

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aminocaproic acid pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00286 NCBI chrNW_004955451:11,468,156...11,484,410
Ensembl chrNW_004955451:11,468,290...11,483,073 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00286 NCBI chrNW_004955404:666,142...682,598
Ensembl chrNW_004955404:666,165...682,538 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00286 NCBI chrNW_004955403:22,811,211...22,830,281
Ensembl chrNW_004955403:22,811,380...22,830,563 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00286 NCBI chrNW_004955408:29,644,279...29,665,161
Ensembl chrNW_004955408:29,642,096...29,650,950 		JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00286 NCBI chrNW_004955465:7,444,118...7,617,366
Ensembl chrNW_004955465:7,443,166...7,617,436 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00286 NCBI chrNW_004955406:33,633,911...33,660,506
Ensembl chrNW_004955406:33,632,144...33,660,535 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00286 NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00286 NCBI chrNW_004955423:254,060...264,448
Ensembl chrNW_004955423:254,189...264,159 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00286 NCBI chrNW_004955462:7,695,004...7,757,832
Ensembl chrNW_004955462:7,694,939...7,757,463 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00286 NCBI chrNW_004955404:685,170...692,797
Ensembl chrNW_004955404:680,594...693,665 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00286 NCBI chrNW_004955594:658,686...800,101
Ensembl chrNW_004955594:658,523...802,865 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00286 NCBI chrNW_004955489:5,747,718...5,780,899
Ensembl chrNW_004955489:5,749,187...5,780,866 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00286 NCBI chrNW_004955471:8,806,964...8,814,671
Ensembl chrNW_004955471:8,806,650...8,816,791 		JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00286 NCBI chrNW_004955471:8,824,901...8,832,836
Ensembl chrNW_004955471:8,822,965...8,832,884 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00286 NCBI chrNW_004955471:8,786,910...8,794,947
Ensembl chrNW_004955471:8,786,910...8,795,013 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00286 NCBI chrNW_004955424:1,926,924...1,952,635
Ensembl chrNW_004955424:1,936,772...1,952,635 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00286 NCBI chrNW_004955403:22,835,544...22,856,355
Ensembl chrNW_004955403:22,833,982...22,856,389 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00286 NCBI chrNW_004955536:730,962...754,333
Ensembl chrNW_004955536:730,981...756,394 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00286 NCBI chrNW_004955439:20,317,814...20,366,724
Ensembl chrNW_004955439:20,317,552...20,366,475 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00286 NCBI chrNW_004955493:7,928,516...7,931,265 JBrowse link
aprotinin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00288 NCBI chrNW_004955451:11,468,156...11,484,410
Ensembl chrNW_004955451:11,468,290...11,483,073 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00288 NCBI chrNW_004955404:666,142...682,598
Ensembl chrNW_004955404:666,165...682,538 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00288 NCBI chrNW_004955403:22,811,211...22,830,281
Ensembl chrNW_004955403:22,811,380...22,830,563 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00288 NCBI chrNW_004955408:29,644,279...29,665,161
Ensembl chrNW_004955408:29,642,096...29,650,950 		JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00288 NCBI chrNW_004955465:7,444,118...7,617,366
Ensembl chrNW_004955465:7,443,166...7,617,436 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00288 NCBI chrNW_004955406:33,633,911...33,660,506
Ensembl chrNW_004955406:33,632,144...33,660,535 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00288 NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00288 NCBI chrNW_004955423:254,060...264,448
Ensembl chrNW_004955423:254,189...264,159 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00288 NCBI chrNW_004955462:7,695,004...7,757,832
Ensembl chrNW_004955462:7,694,939...7,757,463 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00288 NCBI chrNW_004955404:685,170...692,797
Ensembl chrNW_004955404:680,594...693,665 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00288 NCBI chrNW_004955594:658,686...800,101
Ensembl chrNW_004955594:658,523...802,865 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00288 NCBI chrNW_004955489:5,747,718...5,780,899
Ensembl chrNW_004955489:5,749,187...5,780,866 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00288 NCBI chrNW_004955471:8,806,964...8,814,671
Ensembl chrNW_004955471:8,806,650...8,816,791 		JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00288 NCBI chrNW_004955471:8,824,901...8,832,836
Ensembl chrNW_004955471:8,822,965...8,832,884 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00288 NCBI chrNW_004955471:8,786,910...8,794,947
Ensembl chrNW_004955471:8,786,910...8,795,013 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00288 NCBI chrNW_004955424:1,926,924...1,952,635
Ensembl chrNW_004955424:1,936,772...1,952,635 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00288 NCBI chrNW_004955403:22,835,544...22,856,355
Ensembl chrNW_004955403:22,833,982...22,856,389 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00288 NCBI chrNW_004955536:730,962...754,333
Ensembl chrNW_004955536:730,981...756,394 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00288 NCBI chrNW_004955439:20,317,814...20,366,724
Ensembl chrNW_004955439:20,317,552...20,366,475 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00288 NCBI chrNW_004955493:7,928,516...7,931,265 JBrowse link
tranexamic acid pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00287 NCBI chrNW_004955451:11,468,156...11,484,410
Ensembl chrNW_004955451:11,468,290...11,483,073 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00287 NCBI chrNW_004955404:666,142...682,598
Ensembl chrNW_004955404:666,165...682,538 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00287 NCBI chrNW_004955403:22,811,211...22,830,281
Ensembl chrNW_004955403:22,811,380...22,830,563 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00287 NCBI chrNW_004955408:29,644,279...29,665,161
Ensembl chrNW_004955408:29,642,096...29,650,950 		JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00287 NCBI chrNW_004955465:7,444,118...7,617,366
Ensembl chrNW_004955465:7,443,166...7,617,436 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00287 NCBI chrNW_004955406:33,633,911...33,660,506
Ensembl chrNW_004955406:33,632,144...33,660,535 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00287 NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00287 NCBI chrNW_004955423:254,060...264,448
Ensembl chrNW_004955423:254,189...264,159 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00287 NCBI chrNW_004955462:7,695,004...7,757,832
Ensembl chrNW_004955462:7,694,939...7,757,463 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00287 NCBI chrNW_004955404:685,170...692,797
Ensembl chrNW_004955404:680,594...693,665 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00287 NCBI chrNW_004955594:658,686...800,101
Ensembl chrNW_004955594:658,523...802,865 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00287 NCBI chrNW_004955489:5,747,718...5,780,899
Ensembl chrNW_004955489:5,749,187...5,780,866 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00287 NCBI chrNW_004955471:8,806,964...8,814,671
Ensembl chrNW_004955471:8,806,650...8,816,791 		JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00287 NCBI chrNW_004955471:8,824,901...8,832,836
Ensembl chrNW_004955471:8,822,965...8,832,884 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00287 NCBI chrNW_004955471:8,786,910...8,794,947
Ensembl chrNW_004955471:8,786,910...8,795,013 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00287 NCBI chrNW_004955424:1,926,924...1,952,635
Ensembl chrNW_004955424:1,936,772...1,952,635 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00287 NCBI chrNW_004955403:22,835,544...22,856,355
Ensembl chrNW_004955403:22,833,982...22,856,389 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00287 NCBI chrNW_004955536:730,962...754,333
Ensembl chrNW_004955536:730,981...756,394 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00287 NCBI chrNW_004955439:20,317,814...20,366,724
Ensembl chrNW_004955439:20,317,552...20,366,475 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00287 NCBI chrNW_004955493:7,928,516...7,931,265 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 3924
    drug pathway 348
      blood and blood forming organs drug pathway 49
        antihemorrhagic drug pathway 20
          aminocaproic acid drug pathway + 20
          aprotinin drug pathway + 20
          tranexamic acid drug pathway + 20
paths to the root