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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:antithrombotic drug pathway
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Accession:PW:0001651 term browser browse the term
Definition:The pharmacokinetics and pharmacodynamics pathway of drugs that reduce or prevent the formation of blood clots. They are further classified depending on the blood clotting processes they affect. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: anticoagulant drug pathway

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abciximab pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itga2b integrin subunit alpha 2b ISO SMPDB SMP:00265 NCBI chrNW_004936541:813,815...828,826
Ensembl chrNW_004936541:814,171...828,291 		JBrowse link
G Itgb3 integrin subunit beta 3 ISO SMPDB SMP:00265 NCBI chrNW_004936541:2,822,789...2,871,069
Ensembl chrNW_004936541:2,815,738...2,871,035 		JBrowse link
acenocoumarol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00269 NCBI chrNW_004936490:11,448,552...11,465,836
Ensembl chrNW_004936490:11,448,654...11,464,444 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00269 NCBI chrNW_004936472:475,851...502,341
Ensembl chrNW_004936472:475,333...502,377 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00269 NCBI chrNW_004936597:1,687,511...1,694,782 JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00269 NCBI chrNW_004936534:6,199,066...6,360,374
Ensembl chrNW_004936534:6,199,066...6,361,476 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00269 NCBI chrNW_004936567:6,712,666...6,735,539 JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00269 NCBI chrNW_004936562:2,371,725...2,388,617
Ensembl chrNW_004936562:2,372,044...2,388,650 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00269 NCBI chrNW_004936537:4,637,028...4,647,915
Ensembl chrNW_004936537:4,636,667...4,647,916 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00269 NCBI chrNW_004936481:17,114,441...17,178,902
Ensembl chrNW_004936481:17,114,480...17,178,844 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00269 NCBI chrNW_004936472:505,751...515,375
Ensembl chrNW_004936472:505,751...514,339 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00269 NCBI chrNW_004936927:189,359...301,791
Ensembl chrNW_004936927:190,111...301,609 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00269 NCBI chrNW_004936513:8,052,998...8,090,245
Ensembl chrNW_004936513:8,053,615...8,090,234 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00269 NCBI chrNW_004936576:1,322,406...1,329,743 JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00269 NCBI chrNW_004936576:1,306,076...1,313,485
Ensembl chrNW_004936576:1,306,109...1,313,386 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00269 NCBI chrNW_004936576:1,343,657...1,352,085
Ensembl chrNW_004936576:1,343,661...1,352,143 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00269 NCBI chrNW_004936712:1,696,264...1,709,087
Ensembl chrNW_004936712:1,699,750...1,709,087 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00269 NCBI chrNW_004936554:3,227,395...3,256,710
Ensembl chrNW_004936554:3,228,735...3,256,710 		JBrowse link
G LOC101967202 coagulation factor XI ISO SMPDB SMP:00269 NCBI chrNW_004936554:3,205,539...3,223,228
Ensembl chrNW_004936554:3,205,539...3,219,311 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00269 NCBI chrNW_004936785:476,200...503,371
Ensembl chrNW_004936785:476,078...503,321 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00269 NCBI chrNW_004936489:11,775,243...11,808,482
Ensembl chrNW_004936489:11,775,243...11,805,651 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00269 NCBI chrNW_004936501:13,459,400...13,461,864
Ensembl chrNW_004936501:13,459,022...13,462,174 		JBrowse link
acetylsalicylic acid pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12b arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00083 NCBI chrNW_004936595:1,310,556...1,321,974
Ensembl chrNW_004936595:1,310,534...1,321,985 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00083 NCBI chrNW_004936677:3,232,183...3,241,307
Ensembl chrNW_004936677:3,232,183...3,241,253 		JBrowse link
G Alox15b arachidonate 15-lipoxygenase type B ISO SMPDB SMP:00083 NCBI chrNW_004936595:1,279,944...1,288,321
Ensembl chrNW_004936595:1,279,944...1,288,321 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00083 NCBI chrNW_004936554:7,807,914...7,848,691
Ensembl chrNW_004936554:7,808,355...7,867,931 		JBrowse link
G Cbr1 carbonyl reductase 1 ISO SMPDB SMP:00083 NCBI chrNW_004936500:6,569,708...6,591,266
Ensembl chrNW_004936500:6,458,721...6,591,928 		JBrowse link
G Ephx2 epoxide hydrolase 2 ISO SMPDB SMP:00083 NCBI chrNW_004936675:350,357...392,919
Ensembl chrNW_004936675:350,342...392,551 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 ISO SMPDB SMP:00083 NCBI chrNW_004936619:762,278...791,610 JBrowse link
G Gpx1 glutathione peroxidase 1 ISO SMPDB SMP:00083 NCBI chrNW_004936529:997,943...999,123
Ensembl chrNW_004936529:998,150...998,987 		JBrowse link
G LOC101973029 cytochrome P450 2E1 ISO SMPDB SMP:00083 NCBI chrNW_004936486:19,691,822...19,702,684
Ensembl chrNW_004936486:19,691,822...19,702,102 		JBrowse link
G LOC101973126 cytochrome P450 2U1 ISO SMPDB SMP:00083 NCBI chrNW_004936818:650,593...672,349
Ensembl chrNW_004936818:650,589...672,355 		JBrowse link
G Lta4h leukotriene A4 hydrolase ISO SMPDB SMP:00083 NCBI chrNW_004936507:12,082,373...12,120,078
Ensembl chrNW_004936507:12,082,068...12,120,091 		JBrowse link
G Ltc4s leukotriene C4 synthase ISO SMPDB SMP:00083 NCBI chrNW_004936739:975,494...978,426
Ensembl chrNW_004936739:975,493...978,482 		JBrowse link
G Pla2g4b phospholipase A2 group IVB ISO SMPDB SMP:00083 NCBI chrNW_004936471:5,145,736...5,153,930
Ensembl chrNW_004936471:5,145,502...5,153,498 		JBrowse link
G Prxl2b peroxiredoxin like 2B ISO SMPDB SMP:00083 NCBI chrNW_004936737:998,313...1,000,757
Ensembl chrNW_004936737:998,186...1,000,764 		JBrowse link
G Ptgds prostaglandin D2 synthase ISO SMPDB SMP:00083 NCBI chrNW_004936669:961,246...964,584
Ensembl chrNW_004936669:961,034...965,136 		JBrowse link
G Ptges prostaglandin E synthase ISO SMPDB SMP:00083 NCBI chrNW_004936487:16,959,263...16,968,909
Ensembl chrNW_004936487:16,959,231...16,968,922 		JBrowse link
G Ptgis prostaglandin I2 synthase ISO SMPDB SMP:00083 NCBI chrNW_004936514:4,775,884...4,814,574
Ensembl chrNW_004936514:4,791,031...4,812,027 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00083 NCBI chrNW_004936487:10,745,465...10,758,812
Ensembl chrNW_004936487:10,745,327...10,758,823 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00083 NCBI chrNW_004936481:3,821,564...3,828,086 JBrowse link
G Tbxas1 thromboxane A synthase 1 ISO SMPDB SMP:00083 NCBI chrNW_004936592:4,038,163...4,192,772
Ensembl chrNW_004936592:4,038,074...4,192,808 		JBrowse link
alteplase pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00280 NCBI chrNW_004936490:11,448,552...11,465,836
Ensembl chrNW_004936490:11,448,654...11,464,444 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00280 NCBI chrNW_004936472:475,851...502,341
Ensembl chrNW_004936472:475,333...502,377 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00280 NCBI chrNW_004936597:1,687,511...1,694,782 JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00280 NCBI chrNW_004936534:6,199,066...6,360,374
Ensembl chrNW_004936534:6,199,066...6,361,476 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00280 NCBI chrNW_004936567:6,712,666...6,735,539 JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00280 NCBI chrNW_004936562:2,371,725...2,388,617
Ensembl chrNW_004936562:2,372,044...2,388,650 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00280 NCBI chrNW_004936537:4,637,028...4,647,915
Ensembl chrNW_004936537:4,636,667...4,647,916 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00280 NCBI chrNW_004936481:17,114,441...17,178,902
Ensembl chrNW_004936481:17,114,480...17,178,844 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00280 NCBI chrNW_004936472:505,751...515,375
Ensembl chrNW_004936472:505,751...514,339 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00280 NCBI chrNW_004936927:189,359...301,791
Ensembl chrNW_004936927:190,111...301,609 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00280 NCBI chrNW_004936513:8,052,998...8,090,245
Ensembl chrNW_004936513:8,053,615...8,090,234 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00280 NCBI chrNW_004936576:1,322,406...1,329,743 JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00280 NCBI chrNW_004936576:1,306,076...1,313,485
Ensembl chrNW_004936576:1,306,109...1,313,386 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00280 NCBI chrNW_004936576:1,343,657...1,352,085
Ensembl chrNW_004936576:1,343,661...1,352,143 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00280 NCBI chrNW_004936712:1,696,264...1,709,087
Ensembl chrNW_004936712:1,699,750...1,709,087 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00280 NCBI chrNW_004936554:3,227,395...3,256,710
Ensembl chrNW_004936554:3,228,735...3,256,710 		JBrowse link
G LOC101967202 coagulation factor XI ISO SMPDB SMP:00280 NCBI chrNW_004936554:3,205,539...3,223,228
Ensembl chrNW_004936554:3,205,539...3,219,311 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00280 NCBI chrNW_004936785:476,200...503,371
Ensembl chrNW_004936785:476,078...503,321 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00280 NCBI chrNW_004936489:11,775,243...11,808,482
Ensembl chrNW_004936489:11,775,243...11,805,651 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00280 NCBI chrNW_004936501:13,459,400...13,461,864
Ensembl chrNW_004936501:13,459,022...13,462,174 		JBrowse link
anistreplase pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00281 NCBI chrNW_004936490:11,448,552...11,465,836
Ensembl chrNW_004936490:11,448,654...11,464,444 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00281 NCBI chrNW_004936472:475,851...502,341
Ensembl chrNW_004936472:475,333...502,377 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00281 NCBI chrNW_004936597:1,687,511...1,694,782 JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00281 NCBI chrNW_004936534:6,199,066...6,360,374
Ensembl chrNW_004936534:6,199,066...6,361,476 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00281 NCBI chrNW_004936567:6,712,666...6,735,539 JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00281 NCBI chrNW_004936562:2,371,725...2,388,617
Ensembl chrNW_004936562:2,372,044...2,388,650 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00281 NCBI chrNW_004936537:4,637,028...4,647,915
Ensembl chrNW_004936537:4,636,667...4,647,916 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00281 NCBI chrNW_004936481:17,114,441...17,178,902
Ensembl chrNW_004936481:17,114,480...17,178,844 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00281 NCBI chrNW_004936472:505,751...515,375
Ensembl chrNW_004936472:505,751...514,339 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00281 NCBI chrNW_004936927:189,359...301,791
Ensembl chrNW_004936927:190,111...301,609 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00281 NCBI chrNW_004936513:8,052,998...8,090,245
Ensembl chrNW_004936513:8,053,615...8,090,234 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00281 NCBI chrNW_004936576:1,322,406...1,329,743 JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00281 NCBI chrNW_004936576:1,306,076...1,313,485
Ensembl chrNW_004936576:1,306,109...1,313,386 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00281 NCBI chrNW_004936576:1,343,657...1,352,085
Ensembl chrNW_004936576:1,343,661...1,352,143 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00281 NCBI chrNW_004936712:1,696,264...1,709,087
Ensembl chrNW_004936712:1,699,750...1,709,087 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00281 NCBI chrNW_004936554:3,227,395...3,256,710
Ensembl chrNW_004936554:3,228,735...3,256,710 		JBrowse link
G LOC101967202 coagulation factor XI ISO SMPDB SMP:00281 NCBI chrNW_004936554:3,205,539...3,223,228
Ensembl chrNW_004936554:3,205,539...3,219,311 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00281 NCBI chrNW_004936785:476,200...503,371
Ensembl chrNW_004936785:476,078...503,321 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00281 NCBI chrNW_004936489:11,775,243...11,808,482
Ensembl chrNW_004936489:11,775,243...11,805,651 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00281 NCBI chrNW_004936501:13,459,400...13,461,864
Ensembl chrNW_004936501:13,459,022...13,462,174 		JBrowse link
argatroban pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00276 NCBI chrNW_004936490:11,448,552...11,465,836
Ensembl chrNW_004936490:11,448,654...11,464,444 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00276 NCBI chrNW_004936472:475,851...502,341
Ensembl chrNW_004936472:475,333...502,377 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00276 NCBI chrNW_004936597:1,687,511...1,694,782 JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00276 NCBI chrNW_004936534:6,199,066...6,360,374
Ensembl chrNW_004936534:6,199,066...6,361,476 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00276 NCBI chrNW_004936567:6,712,666...6,735,539 JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00276 NCBI chrNW_004936562:2,371,725...2,388,617
Ensembl chrNW_004936562:2,372,044...2,388,650 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00276 NCBI chrNW_004936537:4,637,028...4,647,915
Ensembl chrNW_004936537:4,636,667...4,647,916 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00276 NCBI chrNW_004936481:17,114,441...17,178,902
Ensembl chrNW_004936481:17,114,480...17,178,844 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00276 NCBI chrNW_004936472:505,751...515,375
Ensembl chrNW_004936472:505,751...514,339 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00276 NCBI chrNW_004936927:189,359...301,791
Ensembl chrNW_004936927:190,111...301,609 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00276 NCBI chrNW_004936513:8,052,998...8,090,245
Ensembl chrNW_004936513:8,053,615...8,090,234 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00276 NCBI chrNW_004936576:1,322,406...1,329,743 JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00276 NCBI chrNW_004936576:1,306,076...1,313,485
Ensembl chrNW_004936576:1,306,109...1,313,386 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00276 NCBI chrNW_004936576:1,343,657...1,352,085
Ensembl chrNW_004936576:1,343,661...1,352,143 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00276 NCBI chrNW_004936712:1,696,264...1,709,087
Ensembl chrNW_004936712:1,699,750...1,709,087 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00276 NCBI chrNW_004936554:3,227,395...3,256,710
Ensembl chrNW_004936554:3,228,735...3,256,710 		JBrowse link
G LOC101967202 coagulation factor XI ISO SMPDB SMP:00276 NCBI chrNW_004936554:3,205,539...3,223,228
Ensembl chrNW_004936554:3,205,539...3,219,311 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00276 NCBI chrNW_004936785:476,200...503,371
Ensembl chrNW_004936785:476,078...503,321 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00276 NCBI chrNW_004936489:11,775,243...11,808,482
Ensembl chrNW_004936489:11,775,243...11,805,651 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00276 NCBI chrNW_004936501:13,459,400...13,461,864
Ensembl chrNW_004936501:13,459,022...13,462,174 		JBrowse link
bivalirudin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00277 NCBI chrNW_004936490:11,448,552...11,465,836
Ensembl chrNW_004936490:11,448,654...11,464,444 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00277 NCBI chrNW_004936472:475,851...502,341
Ensembl chrNW_004936472:475,333...502,377 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00277 NCBI chrNW_004936597:1,687,511...1,694,782 JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00277 NCBI chrNW_004936534:6,199,066...6,360,374
Ensembl chrNW_004936534:6,199,066...6,361,476 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00277 NCBI chrNW_004936567:6,712,666...6,735,539 JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00277 NCBI chrNW_004936562:2,371,725...2,388,617
Ensembl chrNW_004936562:2,372,044...2,388,650 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00277 NCBI chrNW_004936537:4,637,028...4,647,915
Ensembl chrNW_004936537:4,636,667...4,647,916 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00277 NCBI chrNW_004936481:17,114,441...17,178,902
Ensembl chrNW_004936481:17,114,480...17,178,844 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00277 NCBI chrNW_004936472:505,751...515,375
Ensembl chrNW_004936472:505,751...514,339 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00277 NCBI chrNW_004936927:189,359...301,791
Ensembl chrNW_004936927:190,111...301,609 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00277 NCBI chrNW_004936513:8,052,998...8,090,245
Ensembl chrNW_004936513:8,053,615...8,090,234 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00277 NCBI chrNW_004936576:1,322,406...1,329,743 JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00277 NCBI chrNW_004936576:1,306,076...1,313,485
Ensembl chrNW_004936576:1,306,109...1,313,386 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00277 NCBI chrNW_004936576:1,343,657...1,352,085
Ensembl chrNW_004936576:1,343,661...1,352,143 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00277 NCBI chrNW_004936712:1,696,264...1,709,087
Ensembl chrNW_004936712:1,699,750...1,709,087 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00277 NCBI chrNW_004936554:3,227,395...3,256,710
Ensembl chrNW_004936554:3,228,735...3,256,710 		JBrowse link
G LOC101967202 coagulation factor XI ISO SMPDB SMP:00277 NCBI chrNW_004936554:3,205,539...3,223,228
Ensembl chrNW_004936554:3,205,539...3,219,311 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00277 NCBI chrNW_004936785:476,200...503,371
Ensembl chrNW_004936785:476,078...503,321 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00277 NCBI chrNW_004936489:11,775,243...11,808,482
Ensembl chrNW_004936489:11,775,243...11,805,651 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00277 NCBI chrNW_004936501:13,459,400...13,461,864
Ensembl chrNW_004936501:13,459,022...13,462,174 		JBrowse link
cilostazol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde4d phosphodiesterase 4D ISO SMPDB SMP:00263 NCBI chrNW_004936480:8,123,437...9,235,586
Ensembl chrNW_004936480:8,204,701...9,234,865 		JBrowse link
clopidogrel pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1 ATP binding cassette subfamily B member 1 ISO SMPDB SMP:00260 NCBI chrNW_004936763:1,225,355...1,308,257
Ensembl chrNW_004936763:1,226,482...1,297,427 		JBrowse link
G LOC101969421 cytochrome P450 1A2 ISO SMPDB SMP:00260 NCBI chrNW_004936471:33,704,616...33,709,455
Ensembl chrNW_004936471:33,703,792...33,709,484 		JBrowse link
G P2ry12 purinergic receptor P2Y12 ISO SMPDB SMP:00260 NCBI chrNW_004936758:1,581,828...1,624,332
Ensembl chrNW_004936758:1,581,897...1,592,222 		JBrowse link
G Pon1 paraoxonase 1 ISO SMPDB SMP:00260 NCBI chrNW_004936585:4,954,871...4,979,560
Ensembl chrNW_004936585:4,954,869...4,979,591 		JBrowse link
clopidogrel pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1 ATP binding cassette subfamily B member 1 ISO SMPDB SMP:00610 NCBI chrNW_004936763:1,225,355...1,308,257
Ensembl chrNW_004936763:1,226,482...1,297,427 		JBrowse link
G LOC101969421 cytochrome P450 1A2 ISO SMPDB SMP:00610 NCBI chrNW_004936471:33,704,616...33,709,455
Ensembl chrNW_004936471:33,703,792...33,709,484 		JBrowse link
G P2ry12 purinergic receptor P2Y12 ISO SMPDB SMP:00610 NCBI chrNW_004936758:1,581,828...1,624,332
Ensembl chrNW_004936758:1,581,897...1,592,222 		JBrowse link
G Pon1 paraoxonase 1 ISO SMPDB SMP:00610 NCBI chrNW_004936585:4,954,871...4,979,560
Ensembl chrNW_004936585:4,954,869...4,979,591 		JBrowse link
dicoumarol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004936490:11,448,552...11,465,836
Ensembl chrNW_004936490:11,448,654...11,464,444 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004936472:475,851...502,341
Ensembl chrNW_004936472:475,333...502,377 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004936597:1,687,511...1,694,782 JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004936534:6,199,066...6,360,374
Ensembl chrNW_004936534:6,199,066...6,361,476 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004936567:6,712,666...6,735,539 JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004936562:2,371,725...2,388,617
Ensembl chrNW_004936562:2,372,044...2,388,650 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004936537:4,637,028...4,647,915
Ensembl chrNW_004936537:4,636,667...4,647,916 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004936481:17,114,441...17,178,902
Ensembl chrNW_004936481:17,114,480...17,178,844 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004936472:505,751...515,375
Ensembl chrNW_004936472:505,751...514,339 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004936927:189,359...301,791
Ensembl chrNW_004936927:190,111...301,609 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004936513:8,052,998...8,090,245
Ensembl chrNW_004936513:8,053,615...8,090,234 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004936576:1,322,406...1,329,743 JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004936576:1,306,076...1,313,485
Ensembl chrNW_004936576:1,306,109...1,313,386 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004936576:1,343,657...1,352,085
Ensembl chrNW_004936576:1,343,661...1,352,143 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004936712:1,696,264...1,709,087
Ensembl chrNW_004936712:1,699,750...1,709,087 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004936554:3,227,395...3,256,710
Ensembl chrNW_004936554:3,228,735...3,256,710 		JBrowse link
G LOC101967202 coagulation factor XI ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004936554:3,205,539...3,223,228
Ensembl chrNW_004936554:3,205,539...3,219,311 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004936785:476,200...503,371
Ensembl chrNW_004936785:476,078...503,321 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004936489:11,775,243...11,808,482
Ensembl chrNW_004936489:11,775,243...11,805,651 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004936501:13,459,400...13,461,864
Ensembl chrNW_004936501:13,459,022...13,462,174 		JBrowse link
dipyridamole pharmacodyamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde4d phosphodiesterase 4D ISO SMPDB SMP:00264 NCBI chrNW_004936480:8,123,437...9,235,586
Ensembl chrNW_004936480:8,204,701...9,234,865 		JBrowse link
enoxaparin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00272 NCBI chrNW_004936490:11,448,552...11,465,836
Ensembl chrNW_004936490:11,448,654...11,464,444 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00272 NCBI chrNW_004936472:475,851...502,341
Ensembl chrNW_004936472:475,333...502,377 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00272 NCBI chrNW_004936597:1,687,511...1,694,782 JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00272 NCBI chrNW_004936534:6,199,066...6,360,374
Ensembl chrNW_004936534:6,199,066...6,361,476 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00272 NCBI chrNW_004936567:6,712,666...6,735,539 JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00272 NCBI chrNW_004936562:2,371,725...2,388,617
Ensembl chrNW_004936562:2,372,044...2,388,650 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00272 NCBI chrNW_004936537:4,637,028...4,647,915
Ensembl chrNW_004936537:4,636,667...4,647,916 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00272 NCBI chrNW_004936481:17,114,441...17,178,902
Ensembl chrNW_004936481:17,114,480...17,178,844 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00272 NCBI chrNW_004936472:505,751...515,375
Ensembl chrNW_004936472:505,751...514,339 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00272 NCBI chrNW_004936927:189,359...301,791
Ensembl chrNW_004936927:190,111...301,609 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00272 NCBI chrNW_004936513:8,052,998...8,090,245
Ensembl chrNW_004936513:8,053,615...8,090,234 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00272 NCBI chrNW_004936576:1,322,406...1,329,743 JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00272 NCBI chrNW_004936576:1,306,076...1,313,485
Ensembl chrNW_004936576:1,306,109...1,313,386 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00272 NCBI chrNW_004936576:1,343,657...1,352,085
Ensembl chrNW_004936576:1,343,661...1,352,143 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00272 NCBI chrNW_004936712:1,696,264...1,709,087
Ensembl chrNW_004936712:1,699,750...1,709,087 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00272 NCBI chrNW_004936554:3,227,395...3,256,710
Ensembl chrNW_004936554:3,228,735...3,256,710 		JBrowse link
G LOC101967202 coagulation factor XI ISO SMPDB SMP:00272 NCBI chrNW_004936554:3,205,539...3,223,228
Ensembl chrNW_004936554:3,205,539...3,219,311 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00272 NCBI chrNW_004936785:476,200...503,371
Ensembl chrNW_004936785:476,078...503,321 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00272 NCBI chrNW_004936489:11,775,243...11,808,482
Ensembl chrNW_004936489:11,775,243...11,805,651 		JBrowse link
G Serpinc1 serpin family C member 1 ISO SMPDB SMP:00272 NCBI chrNW_004936481:13,981,014...13,993,750
Ensembl chrNW_004936481:13,981,019...13,993,634 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00272 NCBI chrNW_004936501:13,459,400...13,461,864
Ensembl chrNW_004936501:13,459,022...13,462,174 		JBrowse link
eptifibatide pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itga2b integrin subunit alpha 2b ISO SMPDB SMP:00266 NCBI chrNW_004936541:813,815...828,826
Ensembl chrNW_004936541:814,171...828,291 		JBrowse link
G Itgb3 integrin subunit beta 3 ISO SMPDB SMP:00266 NCBI chrNW_004936541:2,822,789...2,871,069
Ensembl chrNW_004936541:2,815,738...2,871,035 		JBrowse link
fondaparinux pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00273 NCBI chrNW_004936490:11,448,552...11,465,836
Ensembl chrNW_004936490:11,448,654...11,464,444 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00273 NCBI chrNW_004936472:475,851...502,341
Ensembl chrNW_004936472:475,333...502,377 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00273 NCBI chrNW_004936597:1,687,511...1,694,782 JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00273 NCBI chrNW_004936534:6,199,066...6,360,374
Ensembl chrNW_004936534:6,199,066...6,361,476 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00273 NCBI chrNW_004936567:6,712,666...6,735,539 JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00273 NCBI chrNW_004936562:2,371,725...2,388,617
Ensembl chrNW_004936562:2,372,044...2,388,650 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00273 NCBI chrNW_004936537:4,637,028...4,647,915
Ensembl chrNW_004936537:4,636,667...4,647,916 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00273 NCBI chrNW_004936481:17,114,441...17,178,902
Ensembl chrNW_004936481:17,114,480...17,178,844 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00273 NCBI chrNW_004936472:505,751...515,375
Ensembl chrNW_004936472:505,751...514,339 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00273 NCBI chrNW_004936927:189,359...301,791
Ensembl chrNW_004936927:190,111...301,609 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00273 NCBI chrNW_004936513:8,052,998...8,090,245
Ensembl chrNW_004936513:8,053,615...8,090,234 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00273 NCBI chrNW_004936576:1,322,406...1,329,743 JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00273 NCBI chrNW_004936576:1,306,076...1,313,485
Ensembl chrNW_004936576:1,306,109...1,313,386 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00273 NCBI chrNW_004936576:1,343,657...1,352,085
Ensembl chrNW_004936576:1,343,661...1,352,143 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00273 NCBI chrNW_004936712:1,696,264...1,709,087
Ensembl chrNW_004936712:1,699,750...1,709,087 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00273 NCBI chrNW_004936554:3,227,395...3,256,710
Ensembl chrNW_004936554:3,228,735...3,256,710 		JBrowse link
G LOC101967202 coagulation factor XI ISO SMPDB SMP:00273 NCBI chrNW_004936554:3,205,539...3,223,228
Ensembl chrNW_004936554:3,205,539...3,219,311 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00273 NCBI chrNW_004936785:476,200...503,371
Ensembl chrNW_004936785:476,078...503,321 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00273 NCBI chrNW_004936489:11,775,243...11,808,482
Ensembl chrNW_004936489:11,775,243...11,805,651 		JBrowse link
G Serpinc1 serpin family C member 1 ISO SMPDB SMP:00273 NCBI chrNW_004936481:13,981,014...13,993,750
Ensembl chrNW_004936481:13,981,019...13,993,634 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00273 NCBI chrNW_004936501:13,459,400...13,461,864
Ensembl chrNW_004936501:13,459,022...13,462,174 		JBrowse link
heparin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00274 NCBI chrNW_004936490:11,448,552...11,465,836
Ensembl chrNW_004936490:11,448,654...11,464,444 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00274 NCBI chrNW_004936472:475,851...502,341
Ensembl chrNW_004936472:475,333...502,377 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00274 NCBI chrNW_004936597:1,687,511...1,694,782 JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00274 NCBI chrNW_004936534:6,199,066...6,360,374
Ensembl chrNW_004936534:6,199,066...6,361,476 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00274 NCBI chrNW_004936567:6,712,666...6,735,539 JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00274 NCBI chrNW_004936562:2,371,725...2,388,617
Ensembl chrNW_004936562:2,372,044...2,388,650 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00274 NCBI chrNW_004936537:4,637,028...4,647,915
Ensembl chrNW_004936537:4,636,667...4,647,916 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00274 NCBI chrNW_004936481:17,114,441...17,178,902
Ensembl chrNW_004936481:17,114,480...17,178,844 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00274 NCBI chrNW_004936472:505,751...515,375
Ensembl chrNW_004936472:505,751...514,339 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00274 NCBI chrNW_004936927:189,359...301,791
Ensembl chrNW_004936927:190,111...301,609 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00274 NCBI chrNW_004936513:8,052,998...8,090,245
Ensembl chrNW_004936513:8,053,615...8,090,234 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00274 NCBI chrNW_004936576:1,322,406...1,329,743 JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00274 NCBI chrNW_004936576:1,306,076...1,313,485
Ensembl chrNW_004936576:1,306,109...1,313,386 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00274 NCBI chrNW_004936576:1,343,657...1,352,085
Ensembl chrNW_004936576:1,343,661...1,352,143 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00274 NCBI chrNW_004936712:1,696,264...1,709,087
Ensembl chrNW_004936712:1,699,750...1,709,087 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00274 NCBI chrNW_004936554:3,227,395...3,256,710
Ensembl chrNW_004936554:3,228,735...3,256,710 		JBrowse link
G LOC101967202 coagulation factor XI ISO SMPDB SMP:00274 NCBI chrNW_004936554:3,205,539...3,223,228
Ensembl chrNW_004936554:3,205,539...3,219,311 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00274 NCBI chrNW_004936785:476,200...503,371
Ensembl chrNW_004936785:476,078...503,321 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00274 NCBI chrNW_004936489:11,775,243...11,808,482
Ensembl chrNW_004936489:11,775,243...11,805,651 		JBrowse link
G Serpinc1 serpin family C member 1 ISO SMPDB SMP:00274 NCBI chrNW_004936481:13,981,014...13,993,750
Ensembl chrNW_004936481:13,981,019...13,993,634 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00274 NCBI chrNW_004936501:13,459,400...13,461,864
Ensembl chrNW_004936501:13,459,022...13,462,174 		JBrowse link
phenindione pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00655 NCBI chrNW_004936490:11,448,552...11,465,836
Ensembl chrNW_004936490:11,448,654...11,464,444 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00655 NCBI chrNW_004936472:475,851...502,341
Ensembl chrNW_004936472:475,333...502,377 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00655 NCBI chrNW_004936597:1,687,511...1,694,782 JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00655 NCBI chrNW_004936534:6,199,066...6,360,374
Ensembl chrNW_004936534:6,199,066...6,361,476 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00655 NCBI chrNW_004936567:6,712,666...6,735,539 JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00655 NCBI chrNW_004936562:2,371,725...2,388,617
Ensembl chrNW_004936562:2,372,044...2,388,650 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00655 NCBI chrNW_004936537:4,637,028...4,647,915
Ensembl chrNW_004936537:4,636,667...4,647,916 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00655 NCBI chrNW_004936481:17,114,441...17,178,902
Ensembl chrNW_004936481:17,114,480...17,178,844 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00655 NCBI chrNW_004936472:505,751...515,375
Ensembl chrNW_004936472:505,751...514,339 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00655 NCBI chrNW_004936927:189,359...301,791
Ensembl chrNW_004936927:190,111...301,609 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00655 NCBI chrNW_004936513:8,052,998...8,090,245
Ensembl chrNW_004936513:8,053,615...8,090,234 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00655 NCBI chrNW_004936576:1,322,406...1,329,743 JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00655 NCBI chrNW_004936576:1,306,076...1,313,485
Ensembl chrNW_004936576:1,306,109...1,313,386 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00655 NCBI chrNW_004936576:1,343,657...1,352,085
Ensembl chrNW_004936576:1,343,661...1,352,143 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00655 NCBI chrNW_004936712:1,696,264...1,709,087
Ensembl chrNW_004936712:1,699,750...1,709,087 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00655 NCBI chrNW_004936554:3,227,395...3,256,710
Ensembl chrNW_004936554:3,228,735...3,256,710 		JBrowse link
G LOC101967202 coagulation factor XI ISO SMPDB SMP:00655 NCBI chrNW_004936554:3,205,539...3,223,228
Ensembl chrNW_004936554:3,205,539...3,219,311 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00655 NCBI chrNW_004936785:476,200...503,371
Ensembl chrNW_004936785:476,078...503,321 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00655 NCBI chrNW_004936489:11,775,243...11,808,482
Ensembl chrNW_004936489:11,775,243...11,805,651 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00655 NCBI chrNW_004936501:13,459,400...13,461,864
Ensembl chrNW_004936501:13,459,022...13,462,174 		JBrowse link
reteplase pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00285 NCBI chrNW_004936490:11,448,552...11,465,836
Ensembl chrNW_004936490:11,448,654...11,464,444 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00285 NCBI chrNW_004936472:475,851...502,341
Ensembl chrNW_004936472:475,333...502,377 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00285 NCBI chrNW_004936597:1,687,511...1,694,782 JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00285 NCBI chrNW_004936534:6,199,066...6,360,374
Ensembl chrNW_004936534:6,199,066...6,361,476 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00285 NCBI chrNW_004936567:6,712,666...6,735,539 JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00285 NCBI chrNW_004936562:2,371,725...2,388,617
Ensembl chrNW_004936562:2,372,044...2,388,650 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00285 NCBI chrNW_004936537:4,637,028...4,647,915
Ensembl chrNW_004936537:4,636,667...4,647,916 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00285 NCBI chrNW_004936481:17,114,441...17,178,902
Ensembl chrNW_004936481:17,114,480...17,178,844 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00285 NCBI chrNW_004936472:505,751...515,375
Ensembl chrNW_004936472:505,751...514,339 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00285 NCBI chrNW_004936927:189,359...301,791
Ensembl chrNW_004936927:190,111...301,609 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00285 NCBI chrNW_004936513:8,052,998...8,090,245
Ensembl chrNW_004936513:8,053,615...8,090,234 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00285 NCBI chrNW_004936576:1,322,406...1,329,743 JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00285 NCBI chrNW_004936576:1,306,076...1,313,485
Ensembl chrNW_004936576:1,306,109...1,313,386 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00285 NCBI chrNW_004936576:1,343,657...1,352,085
Ensembl chrNW_004936576:1,343,661...1,352,143 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00285 NCBI chrNW_004936712:1,696,264...1,709,087
Ensembl chrNW_004936712:1,699,750...1,709,087 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00285 NCBI chrNW_004936554:3,227,395...3,256,710
Ensembl chrNW_004936554:3,228,735...3,256,710 		JBrowse link
G LOC101967202 coagulation factor XI ISO SMPDB SMP:00285 NCBI chrNW_004936554:3,205,539...3,223,228
Ensembl chrNW_004936554:3,205,539...3,219,311 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00285 NCBI chrNW_004936785:476,200...503,371
Ensembl chrNW_004936785:476,078...503,321 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00285 NCBI chrNW_004936489:11,775,243...11,808,482
Ensembl chrNW_004936489:11,775,243...11,805,651 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00285 NCBI chrNW_004936501:13,459,400...13,461,864
Ensembl chrNW_004936501:13,459,022...13,462,174 		JBrowse link
salicylic acid pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12b arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00709 NCBI chrNW_004936595:1,310,556...1,321,974
Ensembl chrNW_004936595:1,310,534...1,321,985 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00709 NCBI chrNW_004936677:3,232,183...3,241,307
Ensembl chrNW_004936677:3,232,183...3,241,253 		JBrowse link
G Alox15b arachidonate 15-lipoxygenase type B ISO SMPDB SMP:00709 NCBI chrNW_004936595:1,279,944...1,288,321
Ensembl chrNW_004936595:1,279,944...1,288,321 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00709 NCBI chrNW_004936554:7,807,914...7,848,691
Ensembl chrNW_004936554:7,808,355...7,867,931 		JBrowse link
G Cbr1 carbonyl reductase 1 ISO SMPDB SMP:00709 NCBI chrNW_004936500:6,569,708...6,591,266
Ensembl chrNW_004936500:6,458,721...6,591,928 		JBrowse link
G Ephx2 epoxide hydrolase 2 ISO SMPDB SMP:00709 NCBI chrNW_004936675:350,357...392,919
Ensembl chrNW_004936675:350,342...392,551 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 ISO SMPDB SMP:00709 NCBI chrNW_004936619:762,278...791,610 JBrowse link
G Gpx1 glutathione peroxidase 1 ISO SMPDB SMP:00709 NCBI chrNW_004936529:997,943...999,123
Ensembl chrNW_004936529:998,150...998,987 		JBrowse link
G LOC101973029 cytochrome P450 2E1 ISO SMPDB SMP:00709 NCBI chrNW_004936486:19,691,822...19,702,684
Ensembl chrNW_004936486:19,691,822...19,702,102 		JBrowse link
G LOC101973126 cytochrome P450 2U1 ISO SMPDB SMP:00709 NCBI chrNW_004936818:650,593...672,349
Ensembl chrNW_004936818:650,589...672,355 		JBrowse link
G Lta4h leukotriene A4 hydrolase ISO SMPDB SMP:00709 NCBI chrNW_004936507:12,082,373...12,120,078
Ensembl chrNW_004936507:12,082,068...12,120,091 		JBrowse link
G Ltc4s leukotriene C4 synthase ISO SMPDB SMP:00709 NCBI chrNW_004936739:975,494...978,426
Ensembl chrNW_004936739:975,493...978,482 		JBrowse link
G Pla2g4b phospholipase A2 group IVB ISO SMPDB SMP:00709 NCBI chrNW_004936471:5,145,736...5,153,930
Ensembl chrNW_004936471:5,145,502...5,153,498 		JBrowse link
G Prxl2b peroxiredoxin like 2B ISO SMPDB SMP:00709 NCBI chrNW_004936737:998,313...1,000,757
Ensembl chrNW_004936737:998,186...1,000,764 		JBrowse link
G Ptgds prostaglandin D2 synthase ISO SMPDB SMP:00709 NCBI chrNW_004936669:961,246...964,584
Ensembl chrNW_004936669:961,034...965,136 		JBrowse link
G Ptges prostaglandin E synthase ISO SMPDB SMP:00709 NCBI chrNW_004936487:16,959,263...16,968,909
Ensembl chrNW_004936487:16,959,231...16,968,922 		JBrowse link
G Ptgis prostaglandin I2 synthase ISO SMPDB SMP:00709 NCBI chrNW_004936514:4,775,884...4,814,574
Ensembl chrNW_004936514:4,791,031...4,812,027 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00709 NCBI chrNW_004936487:10,745,465...10,758,812
Ensembl chrNW_004936487:10,745,327...10,758,823 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00709 NCBI chrNW_004936481:3,821,564...3,828,086 JBrowse link
G Tbxas1 thromboxane A synthase 1 ISO SMPDB SMP:00709 NCBI chrNW_004936592:4,038,163...4,192,772
Ensembl chrNW_004936592:4,038,074...4,192,808 		JBrowse link
ticlopidine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2ry12 purinergic receptor P2Y12 ISO SMPDB SMP:00261 NCBI chrNW_004936758:1,581,828...1,624,332
Ensembl chrNW_004936758:1,581,897...1,592,222 		JBrowse link
ticlopidine pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2ry12 purinergic receptor P2Y12 ISO SMPDB SMP:00611 NCBI chrNW_004936758:1,581,828...1,624,332
Ensembl chrNW_004936758:1,581,897...1,592,222 		JBrowse link
tirofiban pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itga2b integrin subunit alpha 2b ISO SMPDB SMP:00267 NCBI chrNW_004936541:813,815...828,826
Ensembl chrNW_004936541:814,171...828,291 		JBrowse link
G Itgb3 integrin subunit beta 3 ISO SMPDB SMP:00267 NCBI chrNW_004936541:2,822,789...2,871,069
Ensembl chrNW_004936541:2,815,738...2,871,035 		JBrowse link
warfarin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00268 NCBI chrNW_004936490:11,448,552...11,465,836
Ensembl chrNW_004936490:11,448,654...11,464,444 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00268 NCBI chrNW_004936472:475,851...502,341
Ensembl chrNW_004936472:475,333...502,377 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00268 NCBI chrNW_004936597:1,687,511...1,694,782 JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00268 NCBI chrNW_004936534:6,199,066...6,360,374
Ensembl chrNW_004936534:6,199,066...6,361,476 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00268 NCBI chrNW_004936567:6,712,666...6,735,539 JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00268 NCBI chrNW_004936562:2,371,725...2,388,617
Ensembl chrNW_004936562:2,372,044...2,388,650 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00268 NCBI chrNW_004936537:4,637,028...4,647,915
Ensembl chrNW_004936537:4,636,667...4,647,916 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00268 NCBI chrNW_004936481:17,114,441...17,178,902
Ensembl chrNW_004936481:17,114,480...17,178,844 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00268 NCBI chrNW_004936472:505,751...515,375
Ensembl chrNW_004936472:505,751...514,339 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00268 NCBI chrNW_004936927:189,359...301,791
Ensembl chrNW_004936927:190,111...301,609 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00268 NCBI chrNW_004936513:8,052,998...8,090,245
Ensembl chrNW_004936513:8,053,615...8,090,234 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00268 NCBI chrNW_004936576:1,322,406...1,329,743 JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00268 NCBI chrNW_004936576:1,306,076...1,313,485
Ensembl chrNW_004936576:1,306,109...1,313,386 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00268 NCBI chrNW_004936576:1,343,657...1,352,085
Ensembl chrNW_004936576:1,343,661...1,352,143 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00268 NCBI chrNW_004936712:1,696,264...1,709,087
Ensembl chrNW_004936712:1,699,750...1,709,087 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00268 NCBI chrNW_004936554:3,227,395...3,256,710
Ensembl chrNW_004936554:3,228,735...3,256,710 		JBrowse link
G LOC101967202 coagulation factor XI ISO SMPDB SMP:00268 NCBI chrNW_004936554:3,205,539...3,223,228
Ensembl chrNW_004936554:3,205,539...3,219,311 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00268 NCBI chrNW_004936785:476,200...503,371
Ensembl chrNW_004936785:476,078...503,321 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00268 NCBI chrNW_004936489:11,775,243...11,808,482
Ensembl chrNW_004936489:11,775,243...11,805,651 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB
RGD		 PMID:26287237 RGD:11354881 SMP:00268 NCBI chrNW_004936501:13,459,400...13,461,864
Ensembl chrNW_004936501:13,459,022...13,462,174 		JBrowse link
warfarin pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101969148 cytochrome P450 1A1 ISO RGD PMID:26655108 RGD:11354883 NCBI chrNW_004936471:33,682,730...33,688,332
Ensembl chrNW_004936471:33,682,730...33,688,332 		JBrowse link
G LOC101969421 cytochrome P450 1A2 ISO RGD PMID:26655108 RGD:11354883 NCBI chrNW_004936471:33,704,616...33,709,455
Ensembl chrNW_004936471:33,703,792...33,709,484 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 3945
    drug pathway 362
      blood and blood forming organs drug pathway 49
        antithrombotic drug pathway 49
          anticoagulant drug pathway + 23
          antiplatelet drug pathway + 27
          other antithrombotic drug pathway + 21
          thrombolytic drug pathway + 20
paths to the root