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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:antithrombotic drug pathway
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Accession:PW:0001651 term browser browse the term
Definition:The pharmacokinetics and pharmacodynamics pathway of drugs that reduce or prevent the formation of blood clots. They are further classified depending on the blood clotting processes they affect. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: anticoagulant drug pathway



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abciximab pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itga2b integrin alpha 2b ISO SMPDB SMP:00265 NCBI chr11:102,344,134...102,360,570
Ensembl chr11:102,344,123...102,360,948
JBrowse link
G Itgb3 integrin beta 3 ISO SMPDB SMP:00265 NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302
JBrowse link
acenocoumarol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen, type I, alpha 1 ISO SMPDB SMP:00269 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00269 NCBI chr 8:13,087,308...13,106,676
Ensembl chr 8:13,087,308...13,106,676
JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00269 NCBI chr 8:45,693,696...45,715,092
Ensembl chr 8:45,694,211...45,715,068
JBrowse link
G F12 coagulation factor XII (Hageman factor) ISO SMPDB SMP:00269 NCBI chr13:55,565,771...55,574,617
Ensembl chr13:55,565,771...55,574,606
JBrowse link
G F13a1 coagulation factor XIII, A1 subunit ISO SMPDB SMP:00269 NCBI chr13:37,051,150...37,234,220
Ensembl chr13:37,051,152...37,234,220
JBrowse link
G F13b coagulation factor XIII, beta subunit ISO SMPDB SMP:00269 NCBI chr 1:139,429,285...139,451,496
Ensembl chr 1:139,429,440...139,451,490
JBrowse link
G F2 coagulation factor II ISO SMPDB SMP:00269 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G F3 coagulation factor III ISO SMPDB SMP:00269 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00269 NCBI chr 1:163,979,396...164,048,539
Ensembl chr 1:163,979,407...164,047,846
JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00269 NCBI chr 8:13,075,499...13,085,809
Ensembl chr 8:13,076,034...13,085,809
JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00269 NCBI chr  X:74,213,950...74,426,342
Ensembl chr  X:74,216,321...74,426,221
JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00269 NCBI chr  X:59,044,675...59,076,120
Ensembl chr  X:59,044,824...59,076,119
JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00269 NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934
JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00269 NCBI chr 3:82,949,553...82,957,170
Ensembl chr 3:82,947,448...82,957,170
JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00269 NCBI chr 3:82,915,031...82,922,363
Ensembl chr 3:82,915,031...82,922,356
JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00269 NCBI chr 6:72,391,262...72,407,696
Ensembl chr 6:72,391,291...72,407,695
JBrowse link
G Klkb1 kallikrein B, plasma 1 ISO SMPDB SMP:00269 NCBI chr 8:45,719,725...45,747,872
Ensembl chr 8:45,719,726...45,747,896
JBrowse link
G Plat plasminogen activator, tissue ISO SMPDB SMP:00269 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860
JBrowse link
G Plg plasminogen ISO SMPDB SMP:00269 NCBI chr17:12,597,496...12,638,271
Ensembl chr17:12,597,495...12,638,272
JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 ISO SMPDB SMP:00269 NCBI chr 7:127,492,235...127,494,833
Ensembl chr 7:127,485,399...127,494,626
Ensembl chr 7:127,485,399...127,494,626
JBrowse link
acetylsalicylic acid pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c18 aldo-keto reductase family 1, member C18 ISO SMPDB SMP:00083 NCBI chr13:4,182,614...4,200,645
Ensembl chr13:4,182,614...4,200,653
JBrowse link
G Alox12 arachidonate 12-lipoxygenase ISO SMPDB SMP:00083 NCBI chr11:70,132,283...70,146,206
Ensembl chr11:70,132,283...70,146,179
JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00083 NCBI chr11:69,047,898...69,060,617
Ensembl chr11:69,047,815...69,060,618
JBrowse link
G Alox15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00083 NCBI chr11:70,234,973...70,279,465
Ensembl chr11:70,234,978...70,242,857
JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00083 NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139
JBrowse link
G Alox8 arachidonate 8-lipoxygenase ISO SMPDB SMP:00083 NCBI chr11:69,074,711...69,088,669
Ensembl chr11:69,074,758...69,088,669
JBrowse link
G Cbr1 carbonyl reductase 1 ISO SMPDB SMP:00083 NCBI chr16:93,404,752...93,407,226
Ensembl chr16:93,402,741...93,407,393
JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 ISO SMPDB SMP:00083 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 ISO SMPDB SMP:00083 NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO SMPDB SMP:00083 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Cyp2j9 cytochrome P450, family 2, subfamily j, polypeptide 9 ISO SMPDB SMP:00083 NCBI chr 4:96,456,661...96,480,748
Ensembl chr 4:96,456,666...96,479,815
JBrowse link
G Cyp2u1 cytochrome P450, family 2, subfamily u, polypeptide 1 ISO SMPDB SMP:00083 NCBI chr 3:131,084,140...131,097,806
Ensembl chr 3:131,082,090...131,096,876
JBrowse link
G Cyp4a31 cytochrome P450, family 4, subfamily a, polypeptide 31 ISO SMPDB SMP:00083 NCBI chr 4:115,420,824...115,436,212
Ensembl chr 4:115,420,846...115,436,212
JBrowse link
G Cyp4f13 cytochrome P450, family 4, subfamily f, polypeptide 13 ISO SMPDB SMP:00083 NCBI chr17:33,143,662...33,166,389
Ensembl chr17:33,143,662...33,166,376
JBrowse link
G Cyp4f16 cytochrome P450, family 4, subfamily f, polypeptide 16 ISO SMPDB SMP:00083 NCBI chr17:32,755,517...32,770,772
Ensembl chr17:32,755,532...32,770,772
JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 ISO SMPDB SMP:00083 NCBI chr 8:72,742,326...72,763,512
Ensembl chr 8:72,742,326...72,763,470
JBrowse link
G Ephx2 epoxide hydrolase 2, cytoplasmic ISO SMPDB SMP:00083 NCBI chr14:66,321,821...66,361,971
Ensembl chr14:66,321,823...66,361,949
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 ISO SMPDB SMP:00083 NCBI chr10:75,396,910...75,422,027
Ensembl chr10:75,397,438...75,422,034
JBrowse link
G Gpx1 glutathione peroxidase 1 ISO SMPDB SMP:00083 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
JBrowse link
G Lta4h leukotriene A4 hydrolase ISO SMPDB SMP:00083 NCBI chr10:93,289,258...93,320,758
Ensembl chr10:93,289,273...93,320,737
JBrowse link
G Ltc4s leukotriene C4 synthase ISO SMPDB SMP:00083 NCBI chr11:50,127,288...50,129,378
Ensembl chr11:50,127,288...50,129,443
JBrowse link
G Prxl2b peroxiredoxin like 2B ISO SMPDB SMP:00083 NCBI chr 4:154,980,884...154,983,522
Ensembl chr 4:154,979,961...154,983,592
JBrowse link
G Ptgds prostaglandin D2 synthase (brain) ISO SMPDB SMP:00083 NCBI chr 2:25,356,723...25,360,080
Ensembl chr 2:25,356,721...25,360,058
JBrowse link
G Ptges prostaglandin E synthase ISO SMPDB SMP:00083 NCBI chr 2:30,779,483...30,793,309
Ensembl chr 2:30,779,483...30,819,875
JBrowse link
G Ptgis prostaglandin I2 (prostacyclin) synthase ISO SMPDB SMP:00083 NCBI chr 2:167,045,114...167,095,069
Ensembl chr 2:167,033,725...167,082,524
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00083 NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00083 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Tbxas1 thromboxane A synthase 1, platelet ISO SMPDB SMP:00083 NCBI chr 6:38,817,897...39,061,524
Ensembl chr 6:38,852,338...39,061,519
JBrowse link
alteplase pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen, type I, alpha 1 ISO SMPDB SMP:00280 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00280 NCBI chr 8:13,087,308...13,106,676
Ensembl chr 8:13,087,308...13,106,676
JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00280 NCBI chr 8:45,693,696...45,715,092
Ensembl chr 8:45,694,211...45,715,068
JBrowse link
G F12 coagulation factor XII (Hageman factor) ISO SMPDB SMP:00280 NCBI chr13:55,565,771...55,574,617
Ensembl chr13:55,565,771...55,574,606
JBrowse link
G F13a1 coagulation factor XIII, A1 subunit ISO SMPDB SMP:00280 NCBI chr13:37,051,150...37,234,220
Ensembl chr13:37,051,152...37,234,220
JBrowse link
G F13b coagulation factor XIII, beta subunit ISO SMPDB SMP:00280 NCBI chr 1:139,429,285...139,451,496
Ensembl chr 1:139,429,440...139,451,490
JBrowse link
G F2 coagulation factor II ISO SMPDB SMP:00280 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G F3 coagulation factor III ISO SMPDB SMP:00280 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00280 NCBI chr 1:163,979,396...164,048,539
Ensembl chr 1:163,979,407...164,047,846
JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00280 NCBI chr 8:13,075,499...13,085,809
Ensembl chr 8:13,076,034...13,085,809
JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00280 NCBI chr  X:74,213,950...74,426,342
Ensembl chr  X:74,216,321...74,426,221
JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00280 NCBI chr  X:59,044,675...59,076,120
Ensembl chr  X:59,044,824...59,076,119
JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00280 NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934
JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00280 NCBI chr 3:82,949,553...82,957,170
Ensembl chr 3:82,947,448...82,957,170
JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00280 NCBI chr 3:82,915,031...82,922,363
Ensembl chr 3:82,915,031...82,922,356
JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00280 NCBI chr 6:72,391,262...72,407,696
Ensembl chr 6:72,391,291...72,407,695
JBrowse link
G Klkb1 kallikrein B, plasma 1 ISO SMPDB SMP:00280 NCBI chr 8:45,719,725...45,747,872
Ensembl chr 8:45,719,726...45,747,896
JBrowse link
G Plat plasminogen activator, tissue ISO SMPDB SMP:00280 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860
JBrowse link
G Plg plasminogen ISO SMPDB SMP:00280 NCBI chr17:12,597,496...12,638,271
Ensembl chr17:12,597,495...12,638,272
JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 ISO SMPDB SMP:00280 NCBI chr 7:127,492,235...127,494,833
Ensembl chr 7:127,485,399...127,494,626
Ensembl chr 7:127,485,399...127,494,626
JBrowse link
anistreplase pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen, type I, alpha 1 ISO SMPDB SMP:00281 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00281 NCBI chr 8:13,087,308...13,106,676
Ensembl chr 8:13,087,308...13,106,676
JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00281 NCBI chr 8:45,693,696...45,715,092
Ensembl chr 8:45,694,211...45,715,068
JBrowse link
G F12 coagulation factor XII (Hageman factor) ISO SMPDB SMP:00281 NCBI chr13:55,565,771...55,574,617
Ensembl chr13:55,565,771...55,574,606
JBrowse link
G F13a1 coagulation factor XIII, A1 subunit ISO SMPDB SMP:00281 NCBI chr13:37,051,150...37,234,220
Ensembl chr13:37,051,152...37,234,220
JBrowse link
G F13b coagulation factor XIII, beta subunit ISO SMPDB SMP:00281 NCBI chr 1:139,429,285...139,451,496
Ensembl chr 1:139,429,440...139,451,490
JBrowse link
G F2 coagulation factor II ISO SMPDB SMP:00281 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G F3 coagulation factor III ISO SMPDB SMP:00281 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00281 NCBI chr 1:163,979,396...164,048,539
Ensembl chr 1:163,979,407...164,047,846
JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00281 NCBI chr 8:13,075,499...13,085,809
Ensembl chr 8:13,076,034...13,085,809
JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00281 NCBI chr  X:74,213,950...74,426,342
Ensembl chr  X:74,216,321...74,426,221
JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00281 NCBI chr  X:59,044,675...59,076,120
Ensembl chr  X:59,044,824...59,076,119
JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00281 NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934
JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00281 NCBI chr 3:82,949,553...82,957,170
Ensembl chr 3:82,947,448...82,957,170
JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00281 NCBI chr 3:82,915,031...82,922,363
Ensembl chr 3:82,915,031...82,922,356
JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00281 NCBI chr 6:72,391,262...72,407,696
Ensembl chr 6:72,391,291...72,407,695
JBrowse link
G Klkb1 kallikrein B, plasma 1 ISO SMPDB SMP:00281 NCBI chr 8:45,719,725...45,747,872
Ensembl chr 8:45,719,726...45,747,896
JBrowse link
G Plat plasminogen activator, tissue ISO SMPDB SMP:00281 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860
JBrowse link
G Plg plasminogen ISO SMPDB SMP:00281 NCBI chr17:12,597,496...12,638,271
Ensembl chr17:12,597,495...12,638,272
JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 ISO SMPDB SMP:00281 NCBI chr 7:127,492,235...127,494,833
Ensembl chr 7:127,485,399...127,494,626
Ensembl chr 7:127,485,399...127,494,626
JBrowse link
argatroban pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen, type I, alpha 1 ISO SMPDB SMP:00276 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00276 NCBI chr 8:13,087,308...13,106,676
Ensembl chr 8:13,087,308...13,106,676
JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00276 NCBI chr 8:45,693,696...45,715,092
Ensembl chr 8:45,694,211...45,715,068
JBrowse link
G F12 coagulation factor XII (Hageman factor) ISO SMPDB SMP:00276 NCBI chr13:55,565,771...55,574,617
Ensembl chr13:55,565,771...55,574,606
JBrowse link
G F13a1 coagulation factor XIII, A1 subunit ISO SMPDB SMP:00276 NCBI chr13:37,051,150...37,234,220
Ensembl chr13:37,051,152...37,234,220
JBrowse link
G F13b coagulation factor XIII, beta subunit ISO SMPDB SMP:00276 NCBI chr 1:139,429,285...139,451,496
Ensembl chr 1:139,429,440...139,451,490
JBrowse link
G F2 coagulation factor II ISO SMPDB SMP:00276 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G F3 coagulation factor III ISO SMPDB SMP:00276 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00276 NCBI chr 1:163,979,396...164,048,539
Ensembl chr 1:163,979,407...164,047,846
JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00276 NCBI chr 8:13,075,499...13,085,809
Ensembl chr 8:13,076,034...13,085,809
JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00276 NCBI chr  X:74,213,950...74,426,342
Ensembl chr  X:74,216,321...74,426,221
JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00276 NCBI chr  X:59,044,675...59,076,120
Ensembl chr  X:59,044,824...59,076,119
JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00276 NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934
JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00276 NCBI chr 3:82,949,553...82,957,170
Ensembl chr 3:82,947,448...82,957,170
JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00276 NCBI chr 3:82,915,031...82,922,363
Ensembl chr 3:82,915,031...82,922,356
JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00276 NCBI chr 6:72,391,262...72,407,696
Ensembl chr 6:72,391,291...72,407,695
JBrowse link
G Klkb1 kallikrein B, plasma 1 ISO SMPDB SMP:00276 NCBI chr 8:45,719,725...45,747,872
Ensembl chr 8:45,719,726...45,747,896
JBrowse link
G Plat plasminogen activator, tissue ISO SMPDB SMP:00276 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860
JBrowse link
G Plg plasminogen ISO SMPDB SMP:00276 NCBI chr17:12,597,496...12,638,271
Ensembl chr17:12,597,495...12,638,272
JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 ISO SMPDB SMP:00276 NCBI chr 7:127,492,235...127,494,833
Ensembl chr 7:127,485,399...127,494,626
Ensembl chr 7:127,485,399...127,494,626
JBrowse link
bivalirudin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen, type I, alpha 1 ISO SMPDB SMP:00277 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00277 NCBI chr 8:13,087,308...13,106,676
Ensembl chr 8:13,087,308...13,106,676
JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00277 NCBI chr 8:45,693,696...45,715,092
Ensembl chr 8:45,694,211...45,715,068
JBrowse link
G F12 coagulation factor XII (Hageman factor) ISO SMPDB SMP:00277 NCBI chr13:55,565,771...55,574,617
Ensembl chr13:55,565,771...55,574,606
JBrowse link
G F13a1 coagulation factor XIII, A1 subunit ISO SMPDB SMP:00277 NCBI chr13:37,051,150...37,234,220
Ensembl chr13:37,051,152...37,234,220
JBrowse link
G F13b coagulation factor XIII, beta subunit ISO SMPDB SMP:00277 NCBI chr 1:139,429,285...139,451,496
Ensembl chr 1:139,429,440...139,451,490
JBrowse link
G F2 coagulation factor II ISO SMPDB SMP:00277 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G F3 coagulation factor III ISO SMPDB SMP:00277 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00277 NCBI chr 1:163,979,396...164,048,539
Ensembl chr 1:163,979,407...164,047,846
JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00277 NCBI chr 8:13,075,499...13,085,809
Ensembl chr 8:13,076,034...13,085,809
JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00277 NCBI chr  X:74,213,950...74,426,342
Ensembl chr  X:74,216,321...74,426,221
JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00277 NCBI chr  X:59,044,675...59,076,120
Ensembl chr  X:59,044,824...59,076,119
JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00277 NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934
JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00277 NCBI chr 3:82,949,553...82,957,170
Ensembl chr 3:82,947,448...82,957,170
JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00277 NCBI chr 3:82,915,031...82,922,363
Ensembl chr 3:82,915,031...82,922,356
JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00277 NCBI chr 6:72,391,262...72,407,696
Ensembl chr 6:72,391,291...72,407,695
JBrowse link
G Klkb1 kallikrein B, plasma 1 ISO SMPDB SMP:00277 NCBI chr 8:45,719,725...45,747,872
Ensembl chr 8:45,719,726...45,747,896
JBrowse link
G Plat plasminogen activator, tissue ISO SMPDB SMP:00277 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860
JBrowse link
G Plg plasminogen ISO SMPDB SMP:00277 NCBI chr17:12,597,496...12,638,271
Ensembl chr17:12,597,495...12,638,272
JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 ISO SMPDB SMP:00277 NCBI chr 7:127,492,235...127,494,833
Ensembl chr 7:127,485,399...127,494,626
Ensembl chr 7:127,485,399...127,494,626
JBrowse link
cilostazol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde4d phosphodiesterase 4D, cAMP specific ISO SMPDB SMP:00263 NCBI chr13:108,790,711...110,092,503
Ensembl chr13:108,586,482...110,089,995
JBrowse link
clopidogrel pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A ISO SMPDB SMP:00260 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 ISO SMPDB SMP:00260 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 ISO SMPDB SMP:00260 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 ISO SMPDB SMP:00260 NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519
JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 ISO SMPDB SMP:00260 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388
JBrowse link
G Cyp2c66 cytochrome P450, family 2, subfamily c, polypeptide 66 ISO SMPDB SMP:00260 NCBI chr19:39,102,342...39,175,200
Ensembl chr19:39,102,342...39,175,516
JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 ISO SMPDB SMP:00260 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774
JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 ISO SMPDB SMP:00260 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881
JBrowse link
G P2ry12 purinergic receptor P2Y, G-protein coupled 12 ISO SMPDB SMP:00260 NCBI chr 3:59,123,692...59,170,408
Ensembl chr 3:59,123,693...59,170,292
JBrowse link
G Pon1 paraoxonase 1 ISO SMPDB SMP:00260 NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946
JBrowse link
clopidogrel pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A ISO SMPDB SMP:00610 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 ISO SMPDB SMP:00610 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 ISO SMPDB SMP:00610 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 ISO SMPDB SMP:00610 NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519
JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 ISO SMPDB SMP:00610 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388
JBrowse link
G Cyp2c66 cytochrome P450, family 2, subfamily c, polypeptide 66 ISO SMPDB SMP:00610 NCBI chr19:39,102,342...39,175,200
Ensembl chr19:39,102,342...39,175,516
JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 ISO SMPDB SMP:00610 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774
JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 ISO SMPDB SMP:00610 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881
JBrowse link
G P2ry12 purinergic receptor P2Y, G-protein coupled 12 ISO SMPDB SMP:00610 NCBI chr 3:59,123,692...59,170,408
Ensembl chr 3:59,123,693...59,170,292
JBrowse link
G Pon1 paraoxonase 1 ISO SMPDB SMP:00610 NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946
JBrowse link
dicoumarol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen, type I, alpha 1 ISO SMPDB SMP:00270 SMP:00656 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00270 SMP:00656 NCBI chr 8:13,087,308...13,106,676
Ensembl chr 8:13,087,308...13,106,676
JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00270 SMP:00656 NCBI chr 8:45,693,696...45,715,092
Ensembl chr 8:45,694,211...45,715,068
JBrowse link
G F12 coagulation factor XII (Hageman factor) ISO SMPDB SMP:00270 SMP:00656 NCBI chr13:55,565,771...55,574,617
Ensembl chr13:55,565,771...55,574,606
JBrowse link
G F13a1 coagulation factor XIII, A1 subunit ISO SMPDB SMP:00270 SMP:00656 NCBI chr13:37,051,150...37,234,220
Ensembl chr13:37,051,152...37,234,220
JBrowse link
G F13b coagulation factor XIII, beta subunit ISO SMPDB SMP:00270 SMP:00656 NCBI chr 1:139,429,285...139,451,496
Ensembl chr 1:139,429,440...139,451,490
JBrowse link
G F2 coagulation factor II ISO SMPDB SMP:00270 SMP:00656 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G F3 coagulation factor III ISO SMPDB SMP:00270 SMP:00656 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00270 SMP:00656 NCBI chr 1:163,979,396...164,048,539
Ensembl chr 1:163,979,407...164,047,846
JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00270 SMP:00656 NCBI chr 8:13,075,499...13,085,809
Ensembl chr 8:13,076,034...13,085,809
JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00270 SMP:00656 NCBI chr  X:74,213,950...74,426,342
Ensembl chr  X:74,216,321...74,426,221
JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00270 SMP:00656 NCBI chr  X:59,044,675...59,076,120
Ensembl chr  X:59,044,824...59,076,119
JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00270 SMP:00656 NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934
JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00270 SMP:00656 NCBI chr 3:82,949,553...82,957,170
Ensembl chr 3:82,947,448...82,957,170
JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00270 SMP:00656 NCBI chr 3:82,915,031...82,922,363
Ensembl chr 3:82,915,031...82,922,356
JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00270 SMP:00656 NCBI chr 6:72,391,262...72,407,696
Ensembl chr 6:72,391,291...72,407,695
JBrowse link
G Klkb1 kallikrein B, plasma 1 ISO SMPDB SMP:00270 SMP:00656 NCBI chr 8:45,719,725...45,747,872
Ensembl chr 8:45,719,726...45,747,896
JBrowse link
G Plat plasminogen activator, tissue ISO SMPDB SMP:00270 SMP:00656 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860
JBrowse link
G Plg plasminogen ISO SMPDB SMP:00270 SMP:00656 NCBI chr17:12,597,496...12,638,271
Ensembl chr17:12,597,495...12,638,272
JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 ISO SMPDB SMP:00270 SMP:00656 NCBI chr 7:127,492,235...127,494,833
Ensembl chr 7:127,485,399...127,494,626
Ensembl chr 7:127,485,399...127,494,626
JBrowse link
dipyridamole pharmacodyamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde4d phosphodiesterase 4D, cAMP specific ISO SMPDB SMP:00264 NCBI chr13:108,790,711...110,092,503
Ensembl chr13:108,586,482...110,089,995
JBrowse link
enoxaparin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen, type I, alpha 1 ISO SMPDB SMP:00272 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00272 NCBI chr 8:13,087,308...13,106,676
Ensembl chr 8:13,087,308...13,106,676
JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00272 NCBI chr 8:45,693,696...45,715,092
Ensembl chr 8:45,694,211...45,715,068
JBrowse link
G F12 coagulation factor XII (Hageman factor) ISO SMPDB SMP:00272 NCBI chr13:55,565,771...55,574,617
Ensembl chr13:55,565,771...55,574,606
JBrowse link
G F13a1 coagulation factor XIII, A1 subunit ISO SMPDB SMP:00272 NCBI chr13:37,051,150...37,234,220
Ensembl chr13:37,051,152...37,234,220
JBrowse link
G F13b coagulation factor XIII, beta subunit ISO SMPDB SMP:00272 NCBI chr 1:139,429,285...139,451,496
Ensembl chr 1:139,429,440...139,451,490
JBrowse link
G F2 coagulation factor II ISO SMPDB SMP:00272 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G F3 coagulation factor III ISO SMPDB SMP:00272 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00272 NCBI chr 1:163,979,396...164,048,539
Ensembl chr 1:163,979,407...164,047,846
JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00272 NCBI chr 8:13,075,499...13,085,809
Ensembl chr 8:13,076,034...13,085,809
JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00272 NCBI chr  X:74,213,950...74,426,342
Ensembl chr  X:74,216,321...74,426,221
JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00272 NCBI chr  X:59,044,675...59,076,120
Ensembl chr  X:59,044,824...59,076,119
JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00272 NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934
JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00272 NCBI chr 3:82,949,553...82,957,170
Ensembl chr 3:82,947,448...82,957,170
JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00272 NCBI chr 3:82,915,031...82,922,363
Ensembl chr 3:82,915,031...82,922,356
JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00272 NCBI chr 6:72,391,262...72,407,696
Ensembl chr 6:72,391,291...72,407,695
JBrowse link
G Klkb1 kallikrein B, plasma 1 ISO SMPDB SMP:00272 NCBI chr 8:45,719,725...45,747,872
Ensembl chr 8:45,719,726...45,747,896
JBrowse link
G Plat plasminogen activator, tissue ISO SMPDB SMP:00272 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860
JBrowse link
G Plg plasminogen ISO SMPDB SMP:00272 NCBI chr17:12,597,496...12,638,271
Ensembl chr17:12,597,495...12,638,272
JBrowse link
G Serpinc1 serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 ISO SMPDB SMP:00272 NCBI chr 1:160,806,153...160,830,113
Ensembl chr 1:160,806,155...160,833,433
JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 ISO SMPDB SMP:00272 NCBI chr 7:127,492,235...127,494,833
Ensembl chr 7:127,485,399...127,494,626
Ensembl chr 7:127,485,399...127,494,626
JBrowse link
eptifibatide pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itga2b integrin alpha 2b ISO SMPDB SMP:00266 NCBI chr11:102,344,134...102,360,570
Ensembl chr11:102,344,123...102,360,948
JBrowse link
G Itgb3 integrin beta 3 ISO SMPDB SMP:00266 NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302
JBrowse link
fondaparinux pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen, type I, alpha 1 ISO SMPDB SMP:00273 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00273 NCBI chr 8:13,087,308...13,106,676
Ensembl chr 8:13,087,308...13,106,676
JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00273 NCBI chr 8:45,693,696...45,715,092
Ensembl chr 8:45,694,211...45,715,068
JBrowse link
G F12 coagulation factor XII (Hageman factor) ISO SMPDB SMP:00273 NCBI chr13:55,565,771...55,574,617
Ensembl chr13:55,565,771...55,574,606
JBrowse link
G F13a1 coagulation factor XIII, A1 subunit ISO SMPDB SMP:00273 NCBI chr13:37,051,150...37,234,220
Ensembl chr13:37,051,152...37,234,220
JBrowse link
G F13b coagulation factor XIII, beta subunit ISO SMPDB SMP:00273 NCBI chr 1:139,429,285...139,451,496
Ensembl chr 1:139,429,440...139,451,490
JBrowse link
G F2 coagulation factor II ISO SMPDB SMP:00273 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G F3 coagulation factor III ISO SMPDB SMP:00273 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00273 NCBI chr 1:163,979,396...164,048,539
Ensembl chr 1:163,979,407...164,047,846
JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00273 NCBI chr 8:13,075,499...13,085,809
Ensembl chr 8:13,076,034...13,085,809
JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00273 NCBI chr  X:74,213,950...74,426,342
Ensembl chr  X:74,216,321...74,426,221
JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00273 NCBI chr  X:59,044,675...59,076,120
Ensembl chr  X:59,044,824...59,076,119
JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00273 NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934
JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00273 NCBI chr 3:82,949,553...82,957,170
Ensembl chr 3:82,947,448...82,957,170
JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00273 NCBI chr 3:82,915,031...82,922,363
Ensembl chr 3:82,915,031...82,922,356
JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00273 NCBI chr 6:72,391,262...72,407,696
Ensembl chr 6:72,391,291...72,407,695
JBrowse link
G Klkb1 kallikrein B, plasma 1 ISO SMPDB SMP:00273 NCBI chr 8:45,719,725...45,747,872
Ensembl chr 8:45,719,726...45,747,896
JBrowse link
G Plat plasminogen activator, tissue ISO SMPDB SMP:00273 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860
JBrowse link
G Plg plasminogen ISO SMPDB SMP:00273 NCBI chr17:12,597,496...12,638,271
Ensembl chr17:12,597,495...12,638,272
JBrowse link
G Serpinc1 serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 ISO SMPDB SMP:00273 NCBI chr 1:160,806,153...160,830,113
Ensembl chr 1:160,806,155...160,833,433
JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 ISO SMPDB SMP:00273 NCBI chr 7:127,492,235...127,494,833
Ensembl chr 7:127,485,399...127,494,626
Ensembl chr 7:127,485,399...127,494,626
JBrowse link
heparin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen, type I, alpha 1 ISO SMPDB SMP:00274 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00274 NCBI chr 8:13,087,308...13,106,676
Ensembl chr 8:13,087,308...13,106,676
JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00274 NCBI chr 8:45,693,696...45,715,092
Ensembl chr 8:45,694,211...45,715,068
JBrowse link
G F12 coagulation factor XII (Hageman factor) ISO SMPDB SMP:00274 NCBI chr13:55,565,771...55,574,617
Ensembl chr13:55,565,771...55,574,606
JBrowse link
G F13a1 coagulation factor XIII, A1 subunit ISO SMPDB SMP:00274 NCBI chr13:37,051,150...37,234,220
Ensembl chr13:37,051,152...37,234,220
JBrowse link
G F13b coagulation factor XIII, beta subunit ISO SMPDB SMP:00274 NCBI chr 1:139,429,285...139,451,496
Ensembl chr 1:139,429,440...139,451,490
JBrowse link
G F2 coagulation factor II ISO SMPDB SMP:00274 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G F3 coagulation factor III ISO SMPDB SMP:00274 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00274 NCBI chr 1:163,979,396...164,048,539
Ensembl chr 1:163,979,407...164,047,846
JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00274 NCBI chr 8:13,075,499...13,085,809
Ensembl chr 8:13,076,034...13,085,809
JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00274 NCBI chr  X:74,213,950...74,426,342
Ensembl chr  X:74,216,321...74,426,221
JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00274 NCBI chr  X:59,044,675...59,076,120
Ensembl chr  X:59,044,824...59,076,119
JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00274 NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934
JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00274 NCBI chr 3:82,949,553...82,957,170
Ensembl chr 3:82,947,448...82,957,170
JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00274 NCBI chr 3:82,915,031...82,922,363
Ensembl chr 3:82,915,031...82,922,356
JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00274 NCBI chr 6:72,391,262...72,407,696
Ensembl chr 6:72,391,291...72,407,695
JBrowse link
G Klkb1 kallikrein B, plasma 1 ISO SMPDB SMP:00274 NCBI chr 8:45,719,725...45,747,872
Ensembl chr 8:45,719,726...45,747,896
JBrowse link
G Plat plasminogen activator, tissue ISO SMPDB SMP:00274 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860
JBrowse link
G Plg plasminogen ISO SMPDB SMP:00274 NCBI chr17:12,597,496...12,638,271
Ensembl chr17:12,597,495...12,638,272
JBrowse link
G Serpinc1 serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 ISO SMPDB SMP:00274 NCBI chr 1:160,806,153...160,830,113
Ensembl chr 1:160,806,155...160,833,433
JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 ISO SMPDB SMP:00274 NCBI chr 7:127,492,235...127,494,833
Ensembl chr 7:127,485,399...127,494,626
Ensembl chr 7:127,485,399...127,494,626
JBrowse link
phenindione pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen, type I, alpha 1 ISO SMPDB SMP:00655 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00655 NCBI chr 8:13,087,308...13,106,676
Ensembl chr 8:13,087,308...13,106,676
JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00655 NCBI chr 8:45,693,696...45,715,092
Ensembl chr 8:45,694,211...45,715,068
JBrowse link
G F12 coagulation factor XII (Hageman factor) ISO SMPDB SMP:00655 NCBI chr13:55,565,771...55,574,617
Ensembl chr13:55,565,771...55,574,606
JBrowse link
G F13a1 coagulation factor XIII, A1 subunit ISO SMPDB SMP:00655 NCBI chr13:37,051,150...37,234,220
Ensembl chr13:37,051,152...37,234,220
JBrowse link
G F13b coagulation factor XIII, beta subunit ISO SMPDB SMP:00655 NCBI chr 1:139,429,285...139,451,496
Ensembl chr 1:139,429,440...139,451,490
JBrowse link
G F2 coagulation factor II ISO SMPDB SMP:00655 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G F3 coagulation factor III ISO SMPDB SMP:00655 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00655 NCBI chr 1:163,979,396...164,048,539
Ensembl chr 1:163,979,407...164,047,846
JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00655 NCBI chr 8:13,075,499...13,085,809
Ensembl chr 8:13,076,034...13,085,809
JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00655 NCBI chr  X:74,213,950...74,426,342
Ensembl chr  X:74,216,321...74,426,221
JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00655 NCBI chr  X:59,044,675...59,076,120
Ensembl chr  X:59,044,824...59,076,119
JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00655 NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934
JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00655 NCBI chr 3:82,949,553...82,957,170
Ensembl chr 3:82,947,448...82,957,170
JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00655 NCBI chr 3:82,915,031...82,922,363
Ensembl chr 3:82,915,031...82,922,356
JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00655 NCBI chr 6:72,391,262...72,407,696
Ensembl chr 6:72,391,291...72,407,695
JBrowse link
G Klkb1 kallikrein B, plasma 1 ISO SMPDB SMP:00655 NCBI chr 8:45,719,725...45,747,872
Ensembl chr 8:45,719,726...45,747,896
JBrowse link
G Plat plasminogen activator, tissue ISO SMPDB SMP:00655 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860
JBrowse link
G Plg plasminogen ISO SMPDB SMP:00655 NCBI chr17:12,597,496...12,638,271
Ensembl chr17:12,597,495...12,638,272
JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 ISO SMPDB SMP:00655 NCBI chr 7:127,492,235...127,494,833
Ensembl chr 7:127,485,399...127,494,626
Ensembl chr 7:127,485,399...127,494,626
JBrowse link
reteplase pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen, type I, alpha 1 ISO SMPDB SMP:00285 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00285 NCBI chr 8:13,087,308...13,106,676
Ensembl chr 8:13,087,308...13,106,676
JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00285 NCBI chr 8:45,693,696...45,715,092
Ensembl chr 8:45,694,211...45,715,068
JBrowse link
G F12 coagulation factor XII (Hageman factor) ISO SMPDB SMP:00285 NCBI chr13:55,565,771...55,574,617
Ensembl chr13:55,565,771...55,574,606
JBrowse link
G F13a1 coagulation factor XIII, A1 subunit ISO SMPDB SMP:00285 NCBI chr13:37,051,150...37,234,220
Ensembl chr13:37,051,152...37,234,220
JBrowse link
G F13b coagulation factor XIII, beta subunit ISO SMPDB SMP:00285 NCBI chr 1:139,429,285...139,451,496
Ensembl chr 1:139,429,440...139,451,490
JBrowse link
G F2 coagulation factor II ISO SMPDB SMP:00285 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G F3 coagulation factor III ISO SMPDB SMP:00285 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00285 NCBI chr 1:163,979,396...164,048,539
Ensembl chr 1:163,979,407...164,047,846
JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00285 NCBI chr 8:13,075,499...13,085,809
Ensembl chr 8:13,076,034...13,085,809
JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00285 NCBI chr  X:74,213,950...74,426,342
Ensembl chr  X:74,216,321...74,426,221
JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00285 NCBI chr  X:59,044,675...59,076,120
Ensembl chr  X:59,044,824...59,076,119
JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00285 NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934
JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00285 NCBI chr 3:82,949,553...82,957,170
Ensembl chr 3:82,947,448...82,957,170
JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00285 NCBI chr 3:82,915,031...82,922,363
Ensembl chr 3:82,915,031...82,922,356
JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00285 NCBI chr 6:72,391,262...72,407,696
Ensembl chr 6:72,391,291...72,407,695
JBrowse link
G Klkb1 kallikrein B, plasma 1 ISO SMPDB SMP:00285 NCBI chr 8:45,719,725...45,747,872
Ensembl chr 8:45,719,726...45,747,896
JBrowse link
G Plat plasminogen activator, tissue ISO SMPDB SMP:00285 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860
JBrowse link
G Plg plasminogen ISO SMPDB SMP:00285 NCBI chr17:12,597,496...12,638,271
Ensembl chr17:12,597,495...12,638,272
JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 ISO SMPDB SMP:00285 NCBI chr 7:127,492,235...127,494,833
Ensembl chr 7:127,485,399...127,494,626
Ensembl chr 7:127,485,399...127,494,626
JBrowse link
salicylic acid pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c18 aldo-keto reductase family 1, member C18 ISO SMPDB SMP:00709 NCBI chr13:4,182,614...4,200,645
Ensembl chr13:4,182,614...4,200,653
JBrowse link
G Alox12 arachidonate 12-lipoxygenase ISO SMPDB SMP:00709 NCBI chr11:70,132,283...70,146,206
Ensembl chr11:70,132,283...70,146,179
JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00709 NCBI chr11:69,047,898...69,060,617
Ensembl chr11:69,047,815...69,060,618
JBrowse link
G Alox15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00709 NCBI chr11:70,234,973...70,279,465
Ensembl chr11:70,234,978...70,242,857
JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00709 NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139
JBrowse link
G Alox8 arachidonate 8-lipoxygenase ISO SMPDB SMP:00709 NCBI chr11:69,074,711...69,088,669
Ensembl chr11:69,074,758...69,088,669
JBrowse link
G Cbr1 carbonyl reductase 1 ISO SMPDB SMP:00709 NCBI chr16:93,404,752...93,407,226
Ensembl chr16:93,402,741...93,407,393
JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 ISO SMPDB SMP:00709 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 ISO SMPDB SMP:00709 NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO SMPDB SMP:00709 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Cyp2j9 cytochrome P450, family 2, subfamily j, polypeptide 9 ISO SMPDB SMP:00709 NCBI chr 4:96,456,661...96,480,748
Ensembl chr 4:96,456,666...96,479,815
JBrowse link
G Cyp2u1 cytochrome P450, family 2, subfamily u, polypeptide 1 ISO SMPDB SMP:00709 NCBI chr 3:131,084,140...131,097,806
Ensembl chr 3:131,082,090...131,096,876
JBrowse link
G Cyp4a31 cytochrome P450, family 4, subfamily a, polypeptide 31 ISO SMPDB SMP:00709 NCBI chr 4:115,420,824...115,436,212
Ensembl chr 4:115,420,846...115,436,212
JBrowse link
G Cyp4f13 cytochrome P450, family 4, subfamily f, polypeptide 13 ISO SMPDB SMP:00709 NCBI chr17:33,143,662...33,166,389
Ensembl chr17:33,143,662...33,166,376
JBrowse link
G Cyp4f16 cytochrome P450, family 4, subfamily f, polypeptide 16 ISO SMPDB SMP:00709 NCBI chr17:32,755,517...32,770,772
Ensembl chr17:32,755,532...32,770,772
JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 ISO SMPDB SMP:00709 NCBI chr 8:72,742,326...72,763,512
Ensembl chr 8:72,742,326...72,763,470
JBrowse link
G Ephx2 epoxide hydrolase 2, cytoplasmic ISO SMPDB SMP:00709 NCBI chr14:66,321,821...66,361,971
Ensembl chr14:66,321,823...66,361,949
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 ISO SMPDB SMP:00709 NCBI chr10:75,396,910...75,422,027
Ensembl chr10:75,397,438...75,422,034
JBrowse link
G Gpx1 glutathione peroxidase 1 ISO SMPDB SMP:00709 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
JBrowse link
G Lta4h leukotriene A4 hydrolase ISO SMPDB SMP:00709 NCBI chr10:93,289,258...93,320,758
Ensembl chr10:93,289,273...93,320,737
JBrowse link
G Ltc4s leukotriene C4 synthase ISO SMPDB SMP:00709 NCBI chr11:50,127,288...50,129,378
Ensembl chr11:50,127,288...50,129,443
JBrowse link
G Prxl2b peroxiredoxin like 2B ISO SMPDB SMP:00709 NCBI chr 4:154,980,884...154,983,522
Ensembl chr 4:154,979,961...154,983,592
JBrowse link
G Ptgds prostaglandin D2 synthase (brain) ISO SMPDB SMP:00709 NCBI chr 2:25,356,723...25,360,080
Ensembl chr 2:25,356,721...25,360,058
JBrowse link
G Ptges prostaglandin E synthase ISO SMPDB SMP:00709 NCBI chr 2:30,779,483...30,793,309
Ensembl chr 2:30,779,483...30,819,875
JBrowse link
G Ptgis prostaglandin I2 (prostacyclin) synthase ISO SMPDB SMP:00709 NCBI chr 2:167,045,114...167,095,069
Ensembl chr 2:167,033,725...167,082,524
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00709 NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00709 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Tbxas1 thromboxane A synthase 1, platelet ISO SMPDB SMP:00709 NCBI chr 6:38,817,897...39,061,524
Ensembl chr 6:38,852,338...39,061,519
JBrowse link
ticlopidine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2ry12 purinergic receptor P2Y, G-protein coupled 12 ISO SMPDB SMP:00261 NCBI chr 3:59,123,692...59,170,408
Ensembl chr 3:59,123,693...59,170,292
JBrowse link
ticlopidine pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2ry12 purinergic receptor P2Y, G-protein coupled 12 ISO SMPDB SMP:00611 NCBI chr 3:59,123,692...59,170,408
Ensembl chr 3:59,123,693...59,170,292
JBrowse link
tirofiban pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itga2b integrin alpha 2b ISO SMPDB SMP:00267 NCBI chr11:102,344,134...102,360,570
Ensembl chr11:102,344,123...102,360,948
JBrowse link
G Itgb3 integrin beta 3 ISO SMPDB SMP:00267 NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302
JBrowse link
warfarin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen, type I, alpha 1 ISO SMPDB SMP:00268 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00268 NCBI chr 8:13,087,308...13,106,676
Ensembl chr 8:13,087,308...13,106,676
JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00268 NCBI chr 8:45,693,696...45,715,092
Ensembl chr 8:45,694,211...45,715,068
JBrowse link
G F12 coagulation factor XII (Hageman factor) ISO SMPDB SMP:00268 NCBI chr13:55,565,771...55,574,617
Ensembl chr13:55,565,771...55,574,606
JBrowse link
G F13a1 coagulation factor XIII, A1 subunit ISO SMPDB SMP:00268 NCBI chr13:37,051,150...37,234,220
Ensembl chr13:37,051,152...37,234,220
JBrowse link
G F13b coagulation factor XIII, beta subunit ISO SMPDB SMP:00268 NCBI chr 1:139,429,285...139,451,496
Ensembl chr 1:139,429,440...139,451,490
JBrowse link
G F2 coagulation factor II ISO SMPDB SMP:00268 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G F3 coagulation factor III ISO SMPDB SMP:00268 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00268 NCBI chr 1:163,979,396...164,048,539
Ensembl chr 1:163,979,407...164,047,846
JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00268 NCBI chr 8:13,075,499...13,085,809
Ensembl chr 8:13,076,034...13,085,809
JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00268 NCBI chr  X:74,213,950...74,426,342
Ensembl chr  X:74,216,321...74,426,221
JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00268 NCBI chr  X:59,044,675...59,076,120
Ensembl chr  X:59,044,824...59,076,119
JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00268 NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934
JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00268 NCBI chr 3:82,949,553...82,957,170
Ensembl chr 3:82,947,448...82,957,170
JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00268 NCBI chr 3:82,915,031...82,922,363
Ensembl chr 3:82,915,031...82,922,356
JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00268 NCBI chr 6:72,391,262...72,407,696
Ensembl chr 6:72,391,291...72,407,695
JBrowse link
G Klkb1 kallikrein B, plasma 1 ISO SMPDB SMP:00268 NCBI chr 8:45,719,725...45,747,872
Ensembl chr 8:45,719,726...45,747,896
JBrowse link
G Plat plasminogen activator, tissue ISO SMPDB SMP:00268 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860
JBrowse link
G Plg plasminogen ISO SMPDB SMP:00268 NCBI chr17:12,597,496...12,638,271
Ensembl chr17:12,597,495...12,638,272
JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 ISO SMPDB
RGD
PMID:26287237 SMP:00268, RGD:11354881 NCBI chr 7:127,492,235...127,494,833
Ensembl chr 7:127,485,399...127,494,626
Ensembl chr 7:127,485,399...127,494,626
JBrowse link
warfarin pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO RGD PMID:26655108 RGD:11354883 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 ISO RGD PMID:26655108 RGD:11354883 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 ISO RGD PMID:26655108 RGD:11354883 NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157
JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 ISO RGD PMID:26655108 RGD:11354883 NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519
JBrowse link
G Cyp2c52-ps cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene ISO RGD PMID:26655108 RGD:11354883 NCBI chr19:38,965,106...38,992,071
Ensembl chr19:38,965,091...38,991,733
JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 ISO RGD PMID:26655108 RGD:11354883 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 ISO RGD PMID:17921187 RGD:11354886 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719
JBrowse link
G Ugt1a10 UDP glycosyltransferase 1 family, polypeptide A10 ISO RGD PMID:17921187 RGD:11354886 NCBI chr 1:87,983,133...88,147,724
Ensembl chr 1:87,983,110...88,146,726
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 ISO RGD PMID:17921187 RGD:11354886 NCBI chr 1:87,998,501...88,147,724
Ensembl chr 1:87,998,522...88,146,719
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6074
    drug pathway 402
      blood and blood forming organs drug pathway 66
        antithrombotic drug pathway 66
          anticoagulant drug pathway + 30
          antiplatelet drug pathway + 40
          other antithrombotic drug pathway + 21
          thrombolytic drug pathway + 20
paths to the root