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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:antithrombotic drug pathway
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Accession:PW:0001651 term browser browse the term
Definition:The pharmacokinetics and pharmacodynamics pathway of drugs that reduce or prevent the formation of blood clots. They are further classified depending on the blood clotting processes they affect. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: anticoagulant drug pathway



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abciximab pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGA2B integrin subunit alpha 2b EXP SMPDB SMP:00265 NCBI chr17:44,372,181...44,389,649
Ensembl chr17:44,372,180...44,389,649
JBrowse link
G ITGB3 integrin subunit beta 3 EXP SMPDB SMP:00265 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,827...47,313,743
JBrowse link
acenocoumarol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain EXP SMPDB SMP:00269 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G F10 coagulation factor X EXP SMPDB SMP:00269 NCBI chr13:113,122,799...113,149,529
Ensembl chr13:113,122,799...113,149,529
JBrowse link
G F11 coagulation factor XI EXP SMPDB SMP:00269 NCBI chr 4:186,266,189...186,289,681
Ensembl chr 4:186,266,189...186,289,681
JBrowse link
G F12 coagulation factor XII EXP SMPDB SMP:00269 NCBI chr 5:177,402,141...177,409,564
Ensembl chr 5:177,402,133...177,416,583
JBrowse link
G F13A1 coagulation factor XIII A chain EXP SMPDB SMP:00269 NCBI chr 6:6,144,084...6,320,662
Ensembl chr 6:6,144,084...6,321,013
JBrowse link
G F13B coagulation factor XIII B chain EXP SMPDB SMP:00269 NCBI chr 1:197,038,741...197,067,260
Ensembl chr 1:197,038,741...197,067,260
JBrowse link
G F2 coagulation factor II, thrombin EXP SMPDB SMP:00269 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G F3 coagulation factor III, tissue factor EXP SMPDB SMP:00269 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G F5 coagulation factor V EXP SMPDB SMP:00269 NCBI chr 1:169,511,951...169,586,481
Ensembl chr 1:169,511,951...169,586,588
JBrowse link
G F7 coagulation factor VII EXP SMPDB SMP:00269 NCBI chr13:113,105,788...113,120,685
Ensembl chr13:113,105,788...113,120,685
JBrowse link
G F8 coagulation factor VIII EXP SMPDB SMP:00269 NCBI chr  X:154,835,792...155,022,723
Ensembl chr  X:154,835,788...155,026,940
JBrowse link
G F9 coagulation factor IX EXP SMPDB SMP:00269 NCBI chr  X:139,530,739...139,563,459
Ensembl chr  X:139,530,739...139,563,459
JBrowse link
G FGA fibrinogen alpha chain EXP SMPDB SMP:00269 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742
JBrowse link
G FGB fibrinogen beta chain EXP SMPDB SMP:00269 NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807
JBrowse link
G FGG fibrinogen gamma chain EXP SMPDB SMP:00269 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967
JBrowse link
G GGCX gamma-glutamyl carboxylase EXP SMPDB SMP:00269 NCBI chr 2:85,544,720...85,561,493
Ensembl chr 2:85,544,720...85,561,532
JBrowse link
G KLKB1 kallikrein B1 EXP SMPDB SMP:00269 NCBI chr 4:186,210,853...186,258,471
Ensembl chr 4:186,226,438...186,258,471
JBrowse link
G PLAT plasminogen activator, tissue type EXP SMPDB SMP:00269 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709
JBrowse link
G PLG plasminogen EXP SMPDB SMP:00269 NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,194...160,754,097
JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 EXP SMPDB SMP:00269 NCBI chr16:31,090,854...31,094,797
Ensembl chr16:31,090,842...31,095,980
JBrowse link
acetylsalicylic acid pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C3 aldo-keto reductase family 1 member C3 EXP SMPDB SMP:00083 NCBI chr10:5,048,781...5,107,686
Ensembl chr10:5,035,354...5,107,686
JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type EXP SMPDB SMP:00083 NCBI chr17:6,996,049...7,010,754
Ensembl chr17:6,996,049...7,010,754
JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type EXP SMPDB SMP:00083 NCBI chr17:8,072,636...8,087,716
Ensembl chr17:8,072,636...8,087,716
JBrowse link
G ALOX15 arachidonate 15-lipoxygenase EXP SMPDB SMP:00083 NCBI chr17:4,630,919...4,641,678
Ensembl chr17:4,630,919...4,642,294
JBrowse link
G ALOX15B arachidonate 15-lipoxygenase type B EXP SMPDB SMP:00083 NCBI chr17:8,039,059...8,049,134
Ensembl chr17:8,039,034...8,049,134
JBrowse link
G ALOX5 arachidonate 5-lipoxygenase EXP SMPDB SMP:00083 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119
JBrowse link
G CBR1 carbonyl reductase 1 EXP SMPDB SMP:00083 NCBI chr21:36,070,024...36,073,164
Ensembl chr21:36,069,941...36,073,166
JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 EXP SMPDB SMP:00083 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 EXP SMPDB SMP:00083 NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 EXP SMPDB SMP:00083 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 EXP SMPDB SMP:00083 NCBI chr 1:59,893,308...59,969,212
Ensembl chr 1:59,893,308...59,926,773
JBrowse link
G CYP2U1 cytochrome P450 family 2 subfamily U member 1 EXP SMPDB SMP:00083 NCBI chr 4:107,931,549...107,953,461
Ensembl chr 4:107,931,549...107,953,461
JBrowse link
G CYP4A11 cytochrome P450 family 4 subfamily A member 11 EXP SMPDB SMP:00083 NCBI chr 1:46,929,188...46,941,476
Ensembl chr 1:46,929,177...46,941,484
JBrowse link
G CYP4F2 cytochrome P450 family 4 subfamily F member 2 EXP SMPDB SMP:00083 NCBI chr19:15,878,023...15,898,074
Ensembl chr19:15,878,023...15,898,077
JBrowse link
G CYP4F3 cytochrome P450 family 4 subfamily F member 3 EXP SMPDB SMP:00083 NCBI chr19:15,640,897...15,662,825
Ensembl chr19:15,640,897...15,662,825
JBrowse link
G CYP4F8 cytochrome P450 family 4 subfamily F member 8 EXP SMPDB SMP:00083 NCBI chr19:15,615,218...15,630,639
Ensembl chr19:15,615,218...15,630,639
JBrowse link
G EPHX2 epoxide hydrolase 2 EXP SMPDB SMP:00083 NCBI chr 8:27,491,143...27,548,626
Ensembl chr 8:27,490,781...27,545,564
JBrowse link
G GGT1 gamma-glutamyltransferase 1 EXP SMPDB SMP:00083 NCBI chr22:24,583,750...24,628,996
Ensembl chr22:24,594,811...24,629,005
JBrowse link
G GPX1 glutathione peroxidase 1 EXP SMPDB SMP:00083 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605
JBrowse link
G LTA4H leukotriene A4 hydrolase EXP SMPDB SMP:00083 NCBI chr12:96,000,753...96,043,520
Ensembl chr12:96,000,753...96,043,520
JBrowse link
G LTC4S leukotriene C4 synthase EXP SMPDB SMP:00083 NCBI chr 5:179,793,986...179,796,647
Ensembl chr 5:179,793,980...179,796,647
JBrowse link
G PLA2G4B phospholipase A2 group IVB EXP SMPDB SMP:00083 NCBI chr15:41,838,847...41,848,143
Ensembl chr15:41,837,775...41,848,147
JBrowse link
G PRXL2B peroxiredoxin like 2B EXP SMPDB SMP:00083 NCBI chr 1:2,586,523...2,591,468
Ensembl chr 1:2,586,491...2,591,469
JBrowse link
G PTGDS prostaglandin D2 synthase EXP SMPDB SMP:00083 NCBI chr 9:136,977,504...136,981,742
Ensembl chr 9:136,975,092...136,981,742
JBrowse link
G PTGES prostaglandin E synthase EXP SMPDB SMP:00083 NCBI chr 9:129,738,349...129,753,042
Ensembl chr 9:129,738,331...129,753,042
JBrowse link
G PTGIS prostaglandin I2 synthase EXP SMPDB SMP:00083 NCBI chr20:49,503,874...49,568,137
Ensembl chr20:49,503,874...49,568,137
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 EXP SMPDB SMP:00083 NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 EXP SMPDB SMP:00083 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G TBXAS1 thromboxane A synthase 1 EXP SMPDB SMP:00083 NCBI chr 7:139,778,242...140,020,293
Ensembl chr 7:139,777,051...140,020,325
JBrowse link
alteplase pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain EXP SMPDB SMP:00280 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G F10 coagulation factor X EXP SMPDB SMP:00280 NCBI chr13:113,122,799...113,149,529
Ensembl chr13:113,122,799...113,149,529
JBrowse link
G F11 coagulation factor XI EXP SMPDB SMP:00280 NCBI chr 4:186,266,189...186,289,681
Ensembl chr 4:186,266,189...186,289,681
JBrowse link
G F12 coagulation factor XII EXP SMPDB SMP:00280 NCBI chr 5:177,402,141...177,409,564
Ensembl chr 5:177,402,133...177,416,583
JBrowse link
G F13A1 coagulation factor XIII A chain EXP SMPDB SMP:00280 NCBI chr 6:6,144,084...6,320,662
Ensembl chr 6:6,144,084...6,321,013
JBrowse link
G F13B coagulation factor XIII B chain EXP SMPDB SMP:00280 NCBI chr 1:197,038,741...197,067,260
Ensembl chr 1:197,038,741...197,067,260
JBrowse link
G F2 coagulation factor II, thrombin EXP SMPDB SMP:00280 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G F3 coagulation factor III, tissue factor EXP SMPDB SMP:00280 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G F5 coagulation factor V EXP SMPDB SMP:00280 NCBI chr 1:169,511,951...169,586,481
Ensembl chr 1:169,511,951...169,586,588
JBrowse link
G F7 coagulation factor VII EXP SMPDB SMP:00280 NCBI chr13:113,105,788...113,120,685
Ensembl chr13:113,105,788...113,120,685
JBrowse link
G F8 coagulation factor VIII EXP SMPDB SMP:00280 NCBI chr  X:154,835,792...155,022,723
Ensembl chr  X:154,835,788...155,026,940
JBrowse link
G F9 coagulation factor IX EXP SMPDB SMP:00280 NCBI chr  X:139,530,739...139,563,459
Ensembl chr  X:139,530,739...139,563,459
JBrowse link
G FGA fibrinogen alpha chain EXP SMPDB SMP:00280 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742
JBrowse link
G FGB fibrinogen beta chain EXP SMPDB SMP:00280 NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807
JBrowse link
G FGG fibrinogen gamma chain EXP SMPDB SMP:00280 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967
JBrowse link
G GGCX gamma-glutamyl carboxylase EXP SMPDB SMP:00280 NCBI chr 2:85,544,720...85,561,493
Ensembl chr 2:85,544,720...85,561,532
JBrowse link
G KLKB1 kallikrein B1 EXP SMPDB SMP:00280 NCBI chr 4:186,210,853...186,258,471
Ensembl chr 4:186,226,438...186,258,471
JBrowse link
G PLAT plasminogen activator, tissue type EXP SMPDB SMP:00280 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709
JBrowse link
G PLG plasminogen EXP SMPDB SMP:00280 NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,194...160,754,097
JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 EXP SMPDB SMP:00280 NCBI chr16:31,090,854...31,094,797
Ensembl chr16:31,090,842...31,095,980
JBrowse link
anistreplase pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain EXP SMPDB SMP:00281 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G F10 coagulation factor X EXP SMPDB SMP:00281 NCBI chr13:113,122,799...113,149,529
Ensembl chr13:113,122,799...113,149,529
JBrowse link
G F11 coagulation factor XI EXP SMPDB SMP:00281 NCBI chr 4:186,266,189...186,289,681
Ensembl chr 4:186,266,189...186,289,681
JBrowse link
G F12 coagulation factor XII EXP SMPDB SMP:00281 NCBI chr 5:177,402,141...177,409,564
Ensembl chr 5:177,402,133...177,416,583
JBrowse link
G F13A1 coagulation factor XIII A chain EXP SMPDB SMP:00281 NCBI chr 6:6,144,084...6,320,662
Ensembl chr 6:6,144,084...6,321,013
JBrowse link
G F13B coagulation factor XIII B chain EXP SMPDB SMP:00281 NCBI chr 1:197,038,741...197,067,260
Ensembl chr 1:197,038,741...197,067,260
JBrowse link
G F2 coagulation factor II, thrombin EXP SMPDB SMP:00281 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G F3 coagulation factor III, tissue factor EXP SMPDB SMP:00281 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G F5 coagulation factor V EXP SMPDB SMP:00281 NCBI chr 1:169,511,951...169,586,481
Ensembl chr 1:169,511,951...169,586,588
JBrowse link
G F7 coagulation factor VII EXP SMPDB SMP:00281 NCBI chr13:113,105,788...113,120,685
Ensembl chr13:113,105,788...113,120,685
JBrowse link
G F8 coagulation factor VIII EXP SMPDB SMP:00281 NCBI chr  X:154,835,792...155,022,723
Ensembl chr  X:154,835,788...155,026,940
JBrowse link
G F9 coagulation factor IX EXP SMPDB SMP:00281 NCBI chr  X:139,530,739...139,563,459
Ensembl chr  X:139,530,739...139,563,459
JBrowse link
G FGA fibrinogen alpha chain EXP SMPDB SMP:00281 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742
JBrowse link
G FGB fibrinogen beta chain EXP SMPDB SMP:00281 NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807
JBrowse link
G FGG fibrinogen gamma chain EXP SMPDB SMP:00281 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967
JBrowse link
G GGCX gamma-glutamyl carboxylase EXP SMPDB SMP:00281 NCBI chr 2:85,544,720...85,561,493
Ensembl chr 2:85,544,720...85,561,532
JBrowse link
G KLKB1 kallikrein B1 EXP SMPDB SMP:00281 NCBI chr 4:186,210,853...186,258,471
Ensembl chr 4:186,226,438...186,258,471
JBrowse link
G PLAT plasminogen activator, tissue type EXP SMPDB SMP:00281 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709
JBrowse link
G PLG plasminogen EXP SMPDB SMP:00281 NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,194...160,754,097
JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 EXP SMPDB SMP:00281 NCBI chr16:31,090,854...31,094,797
Ensembl chr16:31,090,842...31,095,980
JBrowse link
argatroban pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain EXP SMPDB SMP:00276 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G F10 coagulation factor X EXP SMPDB SMP:00276 NCBI chr13:113,122,799...113,149,529
Ensembl chr13:113,122,799...113,149,529
JBrowse link
G F11 coagulation factor XI EXP SMPDB SMP:00276 NCBI chr 4:186,266,189...186,289,681
Ensembl chr 4:186,266,189...186,289,681
JBrowse link
G F12 coagulation factor XII EXP SMPDB SMP:00276 NCBI chr 5:177,402,141...177,409,564
Ensembl chr 5:177,402,133...177,416,583
JBrowse link
G F13A1 coagulation factor XIII A chain EXP SMPDB SMP:00276 NCBI chr 6:6,144,084...6,320,662
Ensembl chr 6:6,144,084...6,321,013
JBrowse link
G F13B coagulation factor XIII B chain EXP SMPDB SMP:00276 NCBI chr 1:197,038,741...197,067,260
Ensembl chr 1:197,038,741...197,067,260
JBrowse link
G F2 coagulation factor II, thrombin EXP SMPDB SMP:00276 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G F3 coagulation factor III, tissue factor EXP SMPDB SMP:00276 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G F5 coagulation factor V EXP SMPDB SMP:00276 NCBI chr 1:169,511,951...169,586,481
Ensembl chr 1:169,511,951...169,586,588
JBrowse link
G F7 coagulation factor VII EXP SMPDB SMP:00276 NCBI chr13:113,105,788...113,120,685
Ensembl chr13:113,105,788...113,120,685
JBrowse link
G F8 coagulation factor VIII EXP SMPDB SMP:00276 NCBI chr  X:154,835,792...155,022,723
Ensembl chr  X:154,835,788...155,026,940
JBrowse link
G F9 coagulation factor IX EXP SMPDB SMP:00276 NCBI chr  X:139,530,739...139,563,459
Ensembl chr  X:139,530,739...139,563,459
JBrowse link
G FGA fibrinogen alpha chain EXP SMPDB SMP:00276 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742
JBrowse link
G FGB fibrinogen beta chain EXP SMPDB SMP:00276 NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807
JBrowse link
G FGG fibrinogen gamma chain EXP SMPDB SMP:00276 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967
JBrowse link
G GGCX gamma-glutamyl carboxylase EXP SMPDB SMP:00276 NCBI chr 2:85,544,720...85,561,493
Ensembl chr 2:85,544,720...85,561,532
JBrowse link
G KLKB1 kallikrein B1 EXP SMPDB SMP:00276 NCBI chr 4:186,210,853...186,258,471
Ensembl chr 4:186,226,438...186,258,471
JBrowse link
G PLAT plasminogen activator, tissue type EXP SMPDB SMP:00276 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709
JBrowse link
G PLG plasminogen EXP SMPDB SMP:00276 NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,194...160,754,097
JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 EXP SMPDB SMP:00276 NCBI chr16:31,090,854...31,094,797
Ensembl chr16:31,090,842...31,095,980
JBrowse link
bivalirudin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain EXP SMPDB SMP:00277 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G F10 coagulation factor X EXP SMPDB SMP:00277 NCBI chr13:113,122,799...113,149,529
Ensembl chr13:113,122,799...113,149,529
JBrowse link
G F11 coagulation factor XI EXP SMPDB SMP:00277 NCBI chr 4:186,266,189...186,289,681
Ensembl chr 4:186,266,189...186,289,681
JBrowse link
G F12 coagulation factor XII EXP SMPDB SMP:00277 NCBI chr 5:177,402,141...177,409,564
Ensembl chr 5:177,402,133...177,416,583
JBrowse link
G F13A1 coagulation factor XIII A chain EXP SMPDB SMP:00277 NCBI chr 6:6,144,084...6,320,662
Ensembl chr 6:6,144,084...6,321,013
JBrowse link
G F13B coagulation factor XIII B chain EXP SMPDB SMP:00277 NCBI chr 1:197,038,741...197,067,260
Ensembl chr 1:197,038,741...197,067,260
JBrowse link
G F2 coagulation factor II, thrombin EXP SMPDB SMP:00277 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G F3 coagulation factor III, tissue factor EXP SMPDB SMP:00277 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G F5 coagulation factor V EXP SMPDB SMP:00277 NCBI chr 1:169,511,951...169,586,481
Ensembl chr 1:169,511,951...169,586,588
JBrowse link
G F7 coagulation factor VII EXP SMPDB SMP:00277 NCBI chr13:113,105,788...113,120,685
Ensembl chr13:113,105,788...113,120,685
JBrowse link
G F8 coagulation factor VIII EXP SMPDB SMP:00277 NCBI chr  X:154,835,792...155,022,723
Ensembl chr  X:154,835,788...155,026,940
JBrowse link
G F9 coagulation factor IX EXP SMPDB SMP:00277 NCBI chr  X:139,530,739...139,563,459
Ensembl chr  X:139,530,739...139,563,459
JBrowse link
G FGA fibrinogen alpha chain EXP SMPDB SMP:00277 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742
JBrowse link
G FGB fibrinogen beta chain EXP SMPDB SMP:00277 NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807
JBrowse link
G FGG fibrinogen gamma chain EXP SMPDB SMP:00277 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967
JBrowse link
G GGCX gamma-glutamyl carboxylase EXP SMPDB SMP:00277 NCBI chr 2:85,544,720...85,561,493
Ensembl chr 2:85,544,720...85,561,532
JBrowse link
G KLKB1 kallikrein B1 EXP SMPDB SMP:00277 NCBI chr 4:186,210,853...186,258,471
Ensembl chr 4:186,226,438...186,258,471
JBrowse link
G PLAT plasminogen activator, tissue type EXP SMPDB SMP:00277 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709
JBrowse link
G PLG plasminogen EXP SMPDB SMP:00277 NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,194...160,754,097
JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 EXP SMPDB SMP:00277 NCBI chr16:31,090,854...31,094,797
Ensembl chr16:31,090,842...31,095,980
JBrowse link
cilostazol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDE4D phosphodiesterase 4D EXP SMPDB SMP:00263 NCBI chr 5:58,969,038...60,522,128
Ensembl chr 5:58,969,038...60,522,120
JBrowse link
clopidogrel pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 EXP SMPDB SMP:00260 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 EXP SMPDB SMP:00260 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 EXP SMPDB SMP:00260 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 EXP SMPDB SMP:00260 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547
JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 EXP SMPDB SMP:00260 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091
JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 EXP SMPDB SMP:00260 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 EXP SMPDB SMP:00260 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996
JBrowse link
G P2RY12 purinergic receptor P2Y12 EXP SMPDB SMP:00260 NCBI chr 3:151,336,843...151,384,753
Ensembl chr 3:151,336,843...151,384,753
JBrowse link
G PON1 paraoxonase 1 EXP SMPDB SMP:00260 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
JBrowse link
clopidogrel pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 EXP SMPDB SMP:00610 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 EXP SMPDB SMP:00610 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 EXP SMPDB SMP:00610 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 EXP SMPDB SMP:00610 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547
JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 EXP SMPDB SMP:00610 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091
JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 EXP SMPDB SMP:00610 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 EXP SMPDB SMP:00610 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996
JBrowse link
G P2RY12 purinergic receptor P2Y12 EXP SMPDB SMP:00610 NCBI chr 3:151,336,843...151,384,753
Ensembl chr 3:151,336,843...151,384,753
JBrowse link
G PON1 paraoxonase 1 EXP SMPDB SMP:00610 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
JBrowse link
dicoumarol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain EXP SMPDB SMP:00270 SMP:00656 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G F10 coagulation factor X EXP SMPDB SMP:00270 SMP:00656 NCBI chr13:113,122,799...113,149,529
Ensembl chr13:113,122,799...113,149,529
JBrowse link
G F11 coagulation factor XI EXP SMPDB SMP:00270 SMP:00656 NCBI chr 4:186,266,189...186,289,681
Ensembl chr 4:186,266,189...186,289,681
JBrowse link
G F12 coagulation factor XII EXP SMPDB SMP:00270 SMP:00656 NCBI chr 5:177,402,141...177,409,564
Ensembl chr 5:177,402,133...177,416,583
JBrowse link
G F13A1 coagulation factor XIII A chain EXP SMPDB SMP:00270 SMP:00656 NCBI chr 6:6,144,084...6,320,662
Ensembl chr 6:6,144,084...6,321,013
JBrowse link
G F13B coagulation factor XIII B chain EXP SMPDB SMP:00270 SMP:00656 NCBI chr 1:197,038,741...197,067,260
Ensembl chr 1:197,038,741...197,067,260
JBrowse link
G F2 coagulation factor II, thrombin EXP SMPDB SMP:00270 SMP:00656 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G F3 coagulation factor III, tissue factor EXP SMPDB SMP:00270 SMP:00656 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G F5 coagulation factor V EXP SMPDB SMP:00270 SMP:00656 NCBI chr 1:169,511,951...169,586,481
Ensembl chr 1:169,511,951...169,586,588
JBrowse link
G F7 coagulation factor VII EXP SMPDB SMP:00270 SMP:00656 NCBI chr13:113,105,788...113,120,685
Ensembl chr13:113,105,788...113,120,685
JBrowse link
G F8 coagulation factor VIII EXP SMPDB SMP:00270 SMP:00656 NCBI chr  X:154,835,792...155,022,723
Ensembl chr  X:154,835,788...155,026,940
JBrowse link
G F9 coagulation factor IX EXP SMPDB SMP:00270 SMP:00656 NCBI chr  X:139,530,739...139,563,459
Ensembl chr  X:139,530,739...139,563,459
JBrowse link
G FGA fibrinogen alpha chain EXP SMPDB SMP:00270 SMP:00656 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742
JBrowse link
G FGB fibrinogen beta chain EXP SMPDB SMP:00270 SMP:00656 NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807
JBrowse link
G FGG fibrinogen gamma chain EXP SMPDB SMP:00270 SMP:00656 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967
JBrowse link
G GGCX gamma-glutamyl carboxylase EXP SMPDB SMP:00270 SMP:00656 NCBI chr 2:85,544,720...85,561,493
Ensembl chr 2:85,544,720...85,561,532
JBrowse link
G KLKB1 kallikrein B1 EXP SMPDB SMP:00270 SMP:00656 NCBI chr 4:186,210,853...186,258,471
Ensembl chr 4:186,226,438...186,258,471
JBrowse link
G PLAT plasminogen activator, tissue type EXP SMPDB SMP:00270 SMP:00656 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709
JBrowse link
G PLG plasminogen EXP SMPDB SMP:00270 SMP:00656 NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,194...160,754,097
JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 EXP SMPDB SMP:00270 SMP:00656 NCBI chr16:31,090,854...31,094,797
Ensembl chr16:31,090,842...31,095,980
JBrowse link
dipyridamole pharmacodyamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDE4D phosphodiesterase 4D EXP SMPDB SMP:00264 NCBI chr 5:58,969,038...60,522,128
Ensembl chr 5:58,969,038...60,522,120
JBrowse link
enoxaparin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain EXP SMPDB SMP:00272 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G F10 coagulation factor X EXP SMPDB SMP:00272 NCBI chr13:113,122,799...113,149,529
Ensembl chr13:113,122,799...113,149,529
JBrowse link
G F11 coagulation factor XI EXP SMPDB SMP:00272 NCBI chr 4:186,266,189...186,289,681
Ensembl chr 4:186,266,189...186,289,681
JBrowse link
G F12 coagulation factor XII EXP SMPDB SMP:00272 NCBI chr 5:177,402,141...177,409,564
Ensembl chr 5:177,402,133...177,416,583
JBrowse link
G F13A1 coagulation factor XIII A chain EXP SMPDB SMP:00272 NCBI chr 6:6,144,084...6,320,662
Ensembl chr 6:6,144,084...6,321,013
JBrowse link
G F13B coagulation factor XIII B chain EXP SMPDB SMP:00272 NCBI chr 1:197,038,741...197,067,260
Ensembl chr 1:197,038,741...197,067,260
JBrowse link
G F2 coagulation factor II, thrombin EXP SMPDB SMP:00272 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G F3 coagulation factor III, tissue factor EXP SMPDB SMP:00272 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G F5 coagulation factor V EXP SMPDB SMP:00272 NCBI chr 1:169,511,951...169,586,481
Ensembl chr 1:169,511,951...169,586,588
JBrowse link
G F7 coagulation factor VII EXP SMPDB SMP:00272 NCBI chr13:113,105,788...113,120,685
Ensembl chr13:113,105,788...113,120,685
JBrowse link
G F8 coagulation factor VIII EXP SMPDB SMP:00272 NCBI chr  X:154,835,792...155,022,723
Ensembl chr  X:154,835,788...155,026,940
JBrowse link
G F9 coagulation factor IX EXP SMPDB SMP:00272 NCBI chr  X:139,530,739...139,563,459
Ensembl chr  X:139,530,739...139,563,459
JBrowse link
G FGA fibrinogen alpha chain EXP SMPDB SMP:00272 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742
JBrowse link
G FGB fibrinogen beta chain EXP SMPDB SMP:00272 NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807
JBrowse link
G FGG fibrinogen gamma chain EXP SMPDB SMP:00272 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967
JBrowse link
G GGCX gamma-glutamyl carboxylase EXP SMPDB SMP:00272 NCBI chr 2:85,544,720...85,561,493
Ensembl chr 2:85,544,720...85,561,532
JBrowse link
G KLKB1 kallikrein B1 EXP SMPDB SMP:00272 NCBI chr 4:186,210,853...186,258,471
Ensembl chr 4:186,226,438...186,258,471
JBrowse link
G PLAT plasminogen activator, tissue type EXP SMPDB SMP:00272 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709
JBrowse link
G PLG plasminogen EXP SMPDB SMP:00272 NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,194...160,754,097
JBrowse link
G SERPINC1 serpin family C member 1 EXP SMPDB SMP:00272 NCBI chr 1:173,903,800...173,917,327
Ensembl chr 1:173,903,800...173,917,327
JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 EXP SMPDB SMP:00272 NCBI chr16:31,090,854...31,094,797
Ensembl chr16:31,090,842...31,095,980
JBrowse link
eptifibatide pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGA2B integrin subunit alpha 2b EXP SMPDB SMP:00266 NCBI chr17:44,372,181...44,389,649
Ensembl chr17:44,372,180...44,389,649
JBrowse link
G ITGB3 integrin subunit beta 3 EXP SMPDB SMP:00266 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,827...47,313,743
JBrowse link
fondaparinux pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain EXP SMPDB SMP:00273 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G F10 coagulation factor X EXP SMPDB SMP:00273 NCBI chr13:113,122,799...113,149,529
Ensembl chr13:113,122,799...113,149,529
JBrowse link
G F11 coagulation factor XI EXP SMPDB SMP:00273 NCBI chr 4:186,266,189...186,289,681
Ensembl chr 4:186,266,189...186,289,681
JBrowse link
G F12 coagulation factor XII EXP SMPDB SMP:00273 NCBI chr 5:177,402,141...177,409,564
Ensembl chr 5:177,402,133...177,416,583
JBrowse link
G F13A1 coagulation factor XIII A chain EXP SMPDB SMP:00273 NCBI chr 6:6,144,084...6,320,662
Ensembl chr 6:6,144,084...6,321,013
JBrowse link
G F13B coagulation factor XIII B chain EXP SMPDB SMP:00273 NCBI chr 1:197,038,741...197,067,260
Ensembl chr 1:197,038,741...197,067,260
JBrowse link
G F2 coagulation factor II, thrombin EXP SMPDB SMP:00273 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G F3 coagulation factor III, tissue factor EXP SMPDB SMP:00273 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G F5 coagulation factor V EXP SMPDB SMP:00273 NCBI chr 1:169,511,951...169,586,481
Ensembl chr 1:169,511,951...169,586,588
JBrowse link
G F7 coagulation factor VII EXP SMPDB SMP:00273 NCBI chr13:113,105,788...113,120,685
Ensembl chr13:113,105,788...113,120,685
JBrowse link
G F8 coagulation factor VIII EXP SMPDB SMP:00273 NCBI chr  X:154,835,792...155,022,723
Ensembl chr  X:154,835,788...155,026,940
JBrowse link
G F9 coagulation factor IX EXP SMPDB SMP:00273 NCBI chr  X:139,530,739...139,563,459
Ensembl chr  X:139,530,739...139,563,459
JBrowse link
G FGA fibrinogen alpha chain EXP SMPDB SMP:00273 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742
JBrowse link
G FGB fibrinogen beta chain EXP SMPDB SMP:00273 NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807
JBrowse link
G FGG fibrinogen gamma chain EXP SMPDB SMP:00273 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967
JBrowse link
G GGCX gamma-glutamyl carboxylase EXP SMPDB SMP:00273 NCBI chr 2:85,544,720...85,561,493
Ensembl chr 2:85,544,720...85,561,532
JBrowse link
G KLKB1 kallikrein B1 EXP SMPDB SMP:00273 NCBI chr 4:186,210,853...186,258,471
Ensembl chr 4:186,226,438...186,258,471
JBrowse link
G PLAT plasminogen activator, tissue type EXP SMPDB SMP:00273 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709
JBrowse link
G PLG plasminogen EXP SMPDB SMP:00273 NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,194...160,754,097
JBrowse link
G SERPINC1 serpin family C member 1 EXP SMPDB SMP:00273 NCBI chr 1:173,903,800...173,917,327
Ensembl chr 1:173,903,800...173,917,327
JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 EXP SMPDB SMP:00273 NCBI chr16:31,090,854...31,094,797
Ensembl chr16:31,090,842...31,095,980
JBrowse link
heparin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain EXP SMPDB SMP:00274 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G F10 coagulation factor X EXP SMPDB SMP:00274 NCBI chr13:113,122,799...113,149,529
Ensembl chr13:113,122,799...113,149,529
JBrowse link
G F11 coagulation factor XI EXP SMPDB SMP:00274 NCBI chr 4:186,266,189...186,289,681
Ensembl chr 4:186,266,189...186,289,681
JBrowse link
G F12 coagulation factor XII EXP SMPDB SMP:00274 NCBI chr 5:177,402,141...177,409,564
Ensembl chr 5:177,402,133...177,416,583
JBrowse link
G F13A1 coagulation factor XIII A chain EXP SMPDB SMP:00274 NCBI chr 6:6,144,084...6,320,662
Ensembl chr 6:6,144,084...6,321,013
JBrowse link
G F13B coagulation factor XIII B chain EXP SMPDB SMP:00274 NCBI chr 1:197,038,741...197,067,260
Ensembl chr 1:197,038,741...197,067,260
JBrowse link
G F2 coagulation factor II, thrombin EXP SMPDB SMP:00274 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G F3 coagulation factor III, tissue factor EXP SMPDB SMP:00274 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G F5 coagulation factor V EXP SMPDB SMP:00274 NCBI chr 1:169,511,951...169,586,481
Ensembl chr 1:169,511,951...169,586,588
JBrowse link
G F7 coagulation factor VII EXP SMPDB SMP:00274 NCBI chr13:113,105,788...113,120,685
Ensembl chr13:113,105,788...113,120,685
JBrowse link
G F8 coagulation factor VIII EXP SMPDB SMP:00274 NCBI chr  X:154,835,792...155,022,723
Ensembl chr  X:154,835,788...155,026,940
JBrowse link
G F9 coagulation factor IX EXP SMPDB SMP:00274 NCBI chr  X:139,530,739...139,563,459
Ensembl chr  X:139,530,739...139,563,459
JBrowse link
G FGA fibrinogen alpha chain EXP SMPDB SMP:00274 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742
JBrowse link
G FGB fibrinogen beta chain EXP SMPDB SMP:00274 NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807
JBrowse link
G FGG fibrinogen gamma chain EXP SMPDB SMP:00274 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967
JBrowse link
G GGCX gamma-glutamyl carboxylase EXP SMPDB SMP:00274 NCBI chr 2:85,544,720...85,561,493
Ensembl chr 2:85,544,720...85,561,532
JBrowse link
G KLKB1 kallikrein B1 EXP SMPDB SMP:00274 NCBI chr 4:186,210,853...186,258,471
Ensembl chr 4:186,226,438...186,258,471
JBrowse link
G PLAT plasminogen activator, tissue type EXP SMPDB SMP:00274 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709
JBrowse link
G PLG plasminogen EXP SMPDB SMP:00274 NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,194...160,754,097
JBrowse link
G SERPINC1 serpin family C member 1 EXP SMPDB SMP:00274 NCBI chr 1:173,903,800...173,917,327
Ensembl chr 1:173,903,800...173,917,327
JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 EXP SMPDB SMP:00274 NCBI chr16:31,090,854...31,094,797
Ensembl chr16:31,090,842...31,095,980
JBrowse link
phenindione pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain EXP SMPDB SMP:00655 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G F10 coagulation factor X EXP SMPDB SMP:00655 NCBI chr13:113,122,799...113,149,529
Ensembl chr13:113,122,799...113,149,529
JBrowse link
G F11 coagulation factor XI EXP SMPDB SMP:00655 NCBI chr 4:186,266,189...186,289,681
Ensembl chr 4:186,266,189...186,289,681
JBrowse link
G F12 coagulation factor XII EXP SMPDB SMP:00655 NCBI chr 5:177,402,141...177,409,564
Ensembl chr 5:177,402,133...177,416,583
JBrowse link
G F13A1 coagulation factor XIII A chain EXP SMPDB SMP:00655 NCBI chr 6:6,144,084...6,320,662
Ensembl chr 6:6,144,084...6,321,013
JBrowse link
G F13B coagulation factor XIII B chain EXP SMPDB SMP:00655 NCBI chr 1:197,038,741...197,067,260
Ensembl chr 1:197,038,741...197,067,260
JBrowse link
G F2 coagulation factor II, thrombin EXP SMPDB SMP:00655 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G F3 coagulation factor III, tissue factor EXP SMPDB SMP:00655 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G F5 coagulation factor V EXP SMPDB SMP:00655 NCBI chr 1:169,511,951...169,586,481
Ensembl chr 1:169,511,951...169,586,588
JBrowse link
G F7 coagulation factor VII EXP SMPDB SMP:00655 NCBI chr13:113,105,788...113,120,685
Ensembl chr13:113,105,788...113,120,685
JBrowse link
G F8 coagulation factor VIII EXP SMPDB SMP:00655 NCBI chr  X:154,835,792...155,022,723
Ensembl chr  X:154,835,788...155,026,940
JBrowse link
G F9 coagulation factor IX EXP SMPDB SMP:00655 NCBI chr  X:139,530,739...139,563,459
Ensembl chr  X:139,530,739...139,563,459
JBrowse link
G FGA fibrinogen alpha chain EXP SMPDB SMP:00655 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742
JBrowse link
G FGB fibrinogen beta chain EXP SMPDB SMP:00655 NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807
JBrowse link
G FGG fibrinogen gamma chain EXP SMPDB SMP:00655 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967
JBrowse link
G GGCX gamma-glutamyl carboxylase EXP SMPDB SMP:00655 NCBI chr 2:85,544,720...85,561,493
Ensembl chr 2:85,544,720...85,561,532
JBrowse link
G KLKB1 kallikrein B1 EXP SMPDB SMP:00655 NCBI chr 4:186,210,853...186,258,471
Ensembl chr 4:186,226,438...186,258,471
JBrowse link
G PLAT plasminogen activator, tissue type EXP SMPDB SMP:00655 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709
JBrowse link
G PLG plasminogen EXP SMPDB SMP:00655 NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,194...160,754,097
JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 EXP SMPDB SMP:00655 NCBI chr16:31,090,854...31,094,797
Ensembl chr16:31,090,842...31,095,980
JBrowse link
reteplase pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain EXP SMPDB SMP:00285 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G F10 coagulation factor X EXP SMPDB SMP:00285 NCBI chr13:113,122,799...113,149,529
Ensembl chr13:113,122,799...113,149,529
JBrowse link
G F11 coagulation factor XI EXP SMPDB SMP:00285 NCBI chr 4:186,266,189...186,289,681
Ensembl chr 4:186,266,189...186,289,681
JBrowse link
G F12 coagulation factor XII EXP SMPDB SMP:00285 NCBI chr 5:177,402,141...177,409,564
Ensembl chr 5:177,402,133...177,416,583
JBrowse link
G F13A1 coagulation factor XIII A chain EXP SMPDB SMP:00285 NCBI chr 6:6,144,084...6,320,662
Ensembl chr 6:6,144,084...6,321,013
JBrowse link
G F13B coagulation factor XIII B chain EXP SMPDB SMP:00285 NCBI chr 1:197,038,741...197,067,260
Ensembl chr 1:197,038,741...197,067,260
JBrowse link
G F2 coagulation factor II, thrombin EXP SMPDB SMP:00285 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G F3 coagulation factor III, tissue factor EXP SMPDB SMP:00285 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G F5 coagulation factor V EXP SMPDB SMP:00285 NCBI chr 1:169,511,951...169,586,481
Ensembl chr 1:169,511,951...169,586,588
JBrowse link
G F7 coagulation factor VII EXP SMPDB SMP:00285 NCBI chr13:113,105,788...113,120,685
Ensembl chr13:113,105,788...113,120,685
JBrowse link
G F8 coagulation factor VIII EXP SMPDB SMP:00285 NCBI chr  X:154,835,792...155,022,723
Ensembl chr  X:154,835,788...155,026,940
JBrowse link
G F9 coagulation factor IX EXP SMPDB SMP:00285 NCBI chr  X:139,530,739...139,563,459
Ensembl chr  X:139,530,739...139,563,459
JBrowse link
G FGA fibrinogen alpha chain EXP SMPDB SMP:00285 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742
JBrowse link
G FGB fibrinogen beta chain EXP SMPDB SMP:00285 NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807
JBrowse link
G FGG fibrinogen gamma chain EXP SMPDB SMP:00285 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967
JBrowse link
G GGCX gamma-glutamyl carboxylase EXP SMPDB SMP:00285 NCBI chr 2:85,544,720...85,561,493
Ensembl chr 2:85,544,720...85,561,532
JBrowse link
G KLKB1 kallikrein B1 EXP SMPDB SMP:00285 NCBI chr 4:186,210,853...186,258,471
Ensembl chr 4:186,226,438...186,258,471
JBrowse link
G PLAT plasminogen activator, tissue type EXP SMPDB SMP:00285 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709
JBrowse link
G PLG plasminogen EXP SMPDB SMP:00285 NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,194...160,754,097
JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 EXP SMPDB SMP:00285 NCBI chr16:31,090,854...31,094,797
Ensembl chr16:31,090,842...31,095,980
JBrowse link
salicylic acid pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C3 aldo-keto reductase family 1 member C3 EXP SMPDB SMP:00709 NCBI chr10:5,048,781...5,107,686
Ensembl chr10:5,035,354...5,107,686
JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type EXP SMPDB SMP:00709 NCBI chr17:6,996,049...7,010,754
Ensembl chr17:6,996,049...7,010,754
JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type EXP SMPDB SMP:00709 NCBI chr17:8,072,636...8,087,716
Ensembl chr17:8,072,636...8,087,716
JBrowse link
G ALOX15 arachidonate 15-lipoxygenase EXP SMPDB SMP:00709 NCBI chr17:4,630,919...4,641,678
Ensembl chr17:4,630,919...4,642,294
JBrowse link
G ALOX15B arachidonate 15-lipoxygenase type B EXP SMPDB SMP:00709 NCBI chr17:8,039,059...8,049,134
Ensembl chr17:8,039,034...8,049,134
JBrowse link
G ALOX5 arachidonate 5-lipoxygenase EXP SMPDB SMP:00709 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119
JBrowse link
G CBR1 carbonyl reductase 1 EXP SMPDB SMP:00709 NCBI chr21:36,070,024...36,073,164
Ensembl chr21:36,069,941...36,073,166
JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 EXP SMPDB SMP:00709 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 EXP SMPDB SMP:00709 NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 EXP SMPDB SMP:00709 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 EXP SMPDB SMP:00709 NCBI chr 1:59,893,308...59,969,212
Ensembl chr 1:59,893,308...59,926,773
JBrowse link
G CYP2U1 cytochrome P450 family 2 subfamily U member 1 EXP SMPDB SMP:00709 NCBI chr 4:107,931,549...107,953,461
Ensembl chr 4:107,931,549...107,953,461
JBrowse link
G CYP4A11 cytochrome P450 family 4 subfamily A member 11 EXP SMPDB SMP:00709 NCBI chr 1:46,929,188...46,941,476
Ensembl chr 1:46,929,177...46,941,484
JBrowse link
G CYP4F2 cytochrome P450 family 4 subfamily F member 2 EXP SMPDB SMP:00709 NCBI chr19:15,878,023...15,898,074
Ensembl chr19:15,878,023...15,898,077
JBrowse link
G CYP4F3 cytochrome P450 family 4 subfamily F member 3 EXP SMPDB SMP:00709 NCBI chr19:15,640,897...15,662,825
Ensembl chr19:15,640,897...15,662,825
JBrowse link
G CYP4F8 cytochrome P450 family 4 subfamily F member 8 EXP SMPDB SMP:00709 NCBI chr19:15,615,218...15,630,639
Ensembl chr19:15,615,218...15,630,639
JBrowse link
G EPHX2 epoxide hydrolase 2 EXP SMPDB SMP:00709 NCBI chr 8:27,491,143...27,548,626
Ensembl chr 8:27,490,781...27,545,564
JBrowse link
G GGT1 gamma-glutamyltransferase 1 EXP SMPDB SMP:00709 NCBI chr22:24,583,750...24,628,996
Ensembl chr22:24,594,811...24,629,005
JBrowse link
G GPX1 glutathione peroxidase 1 EXP SMPDB SMP:00709 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605
JBrowse link
G LTA4H leukotriene A4 hydrolase EXP SMPDB SMP:00709 NCBI chr12:96,000,753...96,043,520
Ensembl chr12:96,000,753...96,043,520
JBrowse link
G LTC4S leukotriene C4 synthase EXP SMPDB SMP:00709 NCBI chr 5:179,793,986...179,796,647
Ensembl chr 5:179,793,980...179,796,647
JBrowse link
G PLA2G4B phospholipase A2 group IVB EXP SMPDB SMP:00709 NCBI chr15:41,838,847...41,848,143
Ensembl chr15:41,837,775...41,848,147
JBrowse link
G PRXL2B peroxiredoxin like 2B EXP SMPDB SMP:00709 NCBI chr 1:2,586,523...2,591,468
Ensembl chr 1:2,586,491...2,591,469
JBrowse link
G PTGDS prostaglandin D2 synthase EXP SMPDB SMP:00709 NCBI chr 9:136,977,504...136,981,742
Ensembl chr 9:136,975,092...136,981,742
JBrowse link
G PTGES prostaglandin E synthase EXP SMPDB SMP:00709 NCBI chr 9:129,738,349...129,753,042
Ensembl chr 9:129,738,331...129,753,042
JBrowse link
G PTGIS prostaglandin I2 synthase EXP SMPDB SMP:00709 NCBI chr20:49,503,874...49,568,137
Ensembl chr20:49,503,874...49,568,137
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 EXP SMPDB SMP:00709 NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 EXP SMPDB SMP:00709 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G TBXAS1 thromboxane A synthase 1 EXP SMPDB SMP:00709 NCBI chr 7:139,778,242...140,020,293
Ensembl chr 7:139,777,051...140,020,325
JBrowse link
ticlopidine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2RY12 purinergic receptor P2Y12 EXP SMPDB SMP:00261 NCBI chr 3:151,336,843...151,384,753
Ensembl chr 3:151,336,843...151,384,753
JBrowse link
ticlopidine pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2RY12 purinergic receptor P2Y12 EXP SMPDB SMP:00611 NCBI chr 3:151,336,843...151,384,753
Ensembl chr 3:151,336,843...151,384,753
JBrowse link
tirofiban pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGA2B integrin subunit alpha 2b EXP SMPDB SMP:00267 NCBI chr17:44,372,181...44,389,649
Ensembl chr17:44,372,180...44,389,649
JBrowse link
G ITGB3 integrin subunit beta 3 EXP SMPDB SMP:00267 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,827...47,313,743
JBrowse link
warfarin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain EXP SMPDB SMP:00268 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G F10 coagulation factor X EXP SMPDB SMP:00268 NCBI chr13:113,122,799...113,149,529
Ensembl chr13:113,122,799...113,149,529
JBrowse link
G F11 coagulation factor XI EXP SMPDB SMP:00268 NCBI chr 4:186,266,189...186,289,681
Ensembl chr 4:186,266,189...186,289,681
JBrowse link
G F12 coagulation factor XII EXP SMPDB SMP:00268 NCBI chr 5:177,402,141...177,409,564
Ensembl chr 5:177,402,133...177,416,583
JBrowse link
G F13A1 coagulation factor XIII A chain EXP SMPDB SMP:00268 NCBI chr 6:6,144,084...6,320,662
Ensembl chr 6:6,144,084...6,321,013
JBrowse link
G F13B coagulation factor XIII B chain EXP SMPDB SMP:00268 NCBI chr 1:197,038,741...197,067,260
Ensembl chr 1:197,038,741...197,067,260
JBrowse link
G F2 coagulation factor II, thrombin EXP SMPDB SMP:00268 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G F3 coagulation factor III, tissue factor EXP SMPDB SMP:00268 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G F5 coagulation factor V EXP SMPDB SMP:00268 NCBI chr 1:169,511,951...169,586,481
Ensembl chr 1:169,511,951...169,586,588
JBrowse link
G F7 coagulation factor VII EXP SMPDB SMP:00268 NCBI chr13:113,105,788...113,120,685
Ensembl chr13:113,105,788...113,120,685
JBrowse link
G F8 coagulation factor VIII EXP SMPDB SMP:00268 NCBI chr  X:154,835,792...155,022,723
Ensembl chr  X:154,835,788...155,026,940
JBrowse link
G F9 coagulation factor IX EXP SMPDB SMP:00268 NCBI chr  X:139,530,739...139,563,459
Ensembl chr  X:139,530,739...139,563,459
JBrowse link
G FGA fibrinogen alpha chain EXP SMPDB SMP:00268 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742
JBrowse link
G FGB fibrinogen beta chain EXP SMPDB SMP:00268 NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807
JBrowse link
G FGG fibrinogen gamma chain EXP SMPDB SMP:00268 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967
JBrowse link
G GGCX gamma-glutamyl carboxylase EXP SMPDB SMP:00268 NCBI chr 2:85,544,720...85,561,493
Ensembl chr 2:85,544,720...85,561,532
JBrowse link
G KLKB1 kallikrein B1 EXP SMPDB SMP:00268 NCBI chr 4:186,210,853...186,258,471
Ensembl chr 4:186,226,438...186,258,471
JBrowse link
G PLAT plasminogen activator, tissue type EXP SMPDB SMP:00268 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709
JBrowse link
G PLG plasminogen EXP SMPDB SMP:00268 NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,194...160,754,097
JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 TAS
EXP
SMPDB
RGD
PMID:26287237 SMP:00268, RGD:11354881 NCBI chr16:31,090,854...31,094,797
Ensembl chr16:31,090,842...31,095,980
JBrowse link
warfarin pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 TAS RGD PMID:26655108 RGD:11354883 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 TAS RGD PMID:26655108 RGD:11354883 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
JBrowse link
G CYP2C18 cytochrome P450 family 2 subfamily C member 18 TAS RGD PMID:26655108 RGD:11354883 NCBI chr10:94,683,729...94,736,190
Ensembl chr10:94,683,729...94,736,190
JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 TAS RGD PMID:26655108 RGD:11354883 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547
JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 TAS RGD PMID:26655108 RGD:11354883 NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497
JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 TAS RGD PMID:26655108 RGD:11354883 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091
JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 TAS RGD PMID:26655108 RGD:11354883 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 IDA RGD PMID:17921187 RGD:11354886 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300
JBrowse link
G UGT1A10 UDP glucuronosyltransferase family 1 member A10 IDA RGD PMID:17921187 RGD:11354886 NCBI chr 2:233,636,448...233,773,300
Ensembl chr 2:233,636,448...233,773,300
JBrowse link
G UGT1A8 UDP glucuronosyltransferase family 1 member A8 IDA RGD PMID:17921187 RGD:11354886 NCBI chr 2:233,617,633...233,773,300
Ensembl chr 2:233,617,633...233,773,300
JBrowse link
G UGT1A9 UDP glucuronosyltransferase family 1 member A9 IDA RGD PMID:17921187 RGD:11354886 NCBI chr 2:233,671,898...233,773,300
Ensembl chr 2:233,671,898...233,773,300
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 5957
    drug pathway 412
      blood and blood forming organs drug pathway 67
        antithrombotic drug pathway 67
          anticoagulant drug pathway + 32
          antiplatelet drug pathway + 40
          other antithrombotic drug pathway + 21
          thrombolytic drug pathway + 20
paths to the root