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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:antithrombotic drug pathway
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Accession:PW:0001651 term browser browse the term
Definition:The pharmacokinetics and pharmacodynamics pathway of drugs that reduce or prevent the formation of blood clots. They are further classified depending on the blood clotting processes they affect. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: anticoagulant drug pathway

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abciximab pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGA2B integrin subunit alpha 2b ISO SMPDB SMP:00265 NCBI chr16:62,001,082...62,019,470
Ensembl chr16:62,001,352...62,019,289 		JBrowse link
G ITGB3 integrin subunit beta 3 ISO SMPDB SMP:00265 NCBI chr16:59,372,171...59,431,434
Ensembl chr16:59,374,889...59,410,857 		JBrowse link
acenocoumarol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00269 NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00269 NCBI chr 3:91,125,097...91,154,000
Ensembl chr 3:91,124,766...91,157,376 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00269 NCBI chr 7:132,180,026...132,207,081
Ensembl chr 7:132,180,336...132,208,155 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00269 NCBI chr23:79,414,074...79,438,896
Ensembl chr23:79,414,225...79,432,298 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00269 NCBI chr17:65,885,498...66,040,026
Ensembl chr17:65,885,658...66,040,040 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00269 NCBI chr25:32,357,540...32,390,349
Ensembl chr25:32,357,993...32,389,973 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00269 NCBI chr20:38,726,690...38,738,457
Ensembl chr20:38,726,798...38,739,408 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00269 NCBI chr25:59,465,610...59,539,022
Ensembl chr25:59,466,378...59,538,872 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00269 NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00269 NCBI chr  X:129,090,140...129,315,343
Ensembl chr  X:129,088,611...129,312,909 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00269 NCBI chr  X:114,618,397...114,650,827
Ensembl chr  X:114,618,639...114,651,365 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00269 NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00269 NCBI chr 7:101,106,468...101,114,566
Ensembl chr 7:101,106,483...101,114,662 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00269 NCBI chr 7:101,148,457...101,157,245
Ensembl chr 7:101,148,058...101,157,111 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00269 NCBI chr14:21,593,202...21,605,800
Ensembl chr14:21,593,088...21,604,885 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00269 NCBI chr 7:132,143,514...132,173,189
Ensembl chr 7:132,144,420...132,173,187 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00269 NCBI chr 8:40,164,391...40,196,627
Ensembl chr 8:40,163,891...40,196,555 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00269 NCBI chr13:88,266,054...88,321,596
Ensembl chr13:88,268,198...88,322,644 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00269 NCBI chr 5:27,778,553...27,782,639
Ensembl chr 5:27,776,416...27,782,640 		JBrowse link
acetylsalicylic acid pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO SMPDB SMP:00083 NCBI chr16:6,355,795...6,370,051
Ensembl chr16:6,356,058...6,369,738 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00083 NCBI chr16:7,454,950...7,470,949
Ensembl chr16:7,455,044...7,469,934 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00083 NCBI chr16:4,112,795...4,121,764
Ensembl chr16:4,111,151...4,121,645 		JBrowse link
G ALOX15B arachidonate 15-lipoxygenase type B ISO SMPDB SMP:00083 NCBI chr16:7,425,533...7,435,896
Ensembl chr16:7,425,990...7,435,327 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00083 NCBI chr 9:41,085,257...41,145,760
Ensembl chr 9:41,085,361...41,145,331 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 ISO SMPDB SMP:00083 NCBI chr 6:35,392,699...35,418,171
Ensembl chr 6:35,393,342...35,418,106 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 ISO SMPDB SMP:00083 NCBI chr 9:88,154,131...88,183,915
Ensembl chr 9:88,154,134...88,183,458 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO SMPDB SMP:00083 NCBI chr26:53,390,054...53,403,309
Ensembl chr26:53,390,089...53,404,211 		JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 ISO SMPDB SMP:00083 NCBI chr20:73,083,312...73,115,174
Ensembl chr20:73,083,389...73,115,077 		JBrowse link
G CYP2U1 cytochrome P450 family 2 subfamily U member 1 ISO SMPDB SMP:00083 NCBI chr 7:55,859,669...55,880,266
Ensembl chr 7:55,859,849...55,879,280 		JBrowse link
G CYP4F3 cytochrome P450 family 4 subfamily F member 3 ISO SMPDB SMP:00083 NCBI chr 6:14,241,352...14,260,799
Ensembl chr 6:14,241,409...14,263,494 		JBrowse link
G CYP4F8 cytochrome P450 family 4 subfamily F member 8 ISO SMPDB SMP:00083 NCBI chr 6:14,211,899...14,229,793
Ensembl chr 6:14,215,337...14,229,509 		JBrowse link
G EPHX2 epoxide hydrolase 2 ISO SMPDB SMP:00083 NCBI chr 8:25,603,668...25,659,232
Ensembl chr 8:25,603,735...25,659,345 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO SMPDB SMP:00083
G GPX1 glutathione peroxidase 1 ISO SMPDB SMP:00083 NCBI chr22:10,754,976...10,756,617 JBrowse link
G LOC103218526 carbonyl reductase [NADPH] 1 ISO SMPDB SMP:00083 NCBI chr 2:80,096,743...80,099,982 JBrowse link
G LTA4H leukotriene A4 hydrolase ISO SMPDB SMP:00083 NCBI chr11:91,371,383...91,413,396
Ensembl chr11:91,371,383...91,406,542 		JBrowse link
G LTC4S leukotriene C4 synthase ISO SMPDB SMP:00083 NCBI chr23:81,523,784...81,526,297
Ensembl chr23:81,523,775...81,526,179 		JBrowse link
G PLA2G4B phospholipase A2 group IVB ISO SMPDB SMP:00083 NCBI chr26:41,137,643...41,147,384 JBrowse link
G PRXL2B peroxiredoxin like 2B ISO SMPDB SMP:00083 NCBI chr20:128,964,750...128,969,469
Ensembl chr20:128,964,987...128,967,620 		JBrowse link
G PTGDS prostaglandin D2 synthase ISO SMPDB SMP:00083 NCBI chr12:1,210,567...1,214,631
Ensembl chr12:1,211,487...1,214,531 		JBrowse link
G PTGES prostaglandin E synthase ISO SMPDB SMP:00083 NCBI chr12:8,393,462...8,408,441
Ensembl chr12:8,393,550...8,408,435 		JBrowse link
G PTGIS prostaglandin I2 synthase ISO SMPDB SMP:00083 NCBI chr 2:14,420,318...14,484,667
Ensembl chr 2:14,441,983...14,488,264 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00083 NCBI chr12:17,195,403...17,218,450
Ensembl chr12:17,192,628...17,218,315 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00083 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429 		JBrowse link
G TBXAS1 thromboxane A synthase 1 ISO SMPDB SMP:00083 NCBI chr21:108,584,458...108,779,357
Ensembl chr21:108,628,570...108,779,163 		JBrowse link
alteplase pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00280 NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00280 NCBI chr 3:91,125,097...91,154,000
Ensembl chr 3:91,124,766...91,157,376 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00280 NCBI chr 7:132,180,026...132,207,081
Ensembl chr 7:132,180,336...132,208,155 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00280 NCBI chr23:79,414,074...79,438,896
Ensembl chr23:79,414,225...79,432,298 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00280 NCBI chr17:65,885,498...66,040,026
Ensembl chr17:65,885,658...66,040,040 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00280 NCBI chr25:32,357,540...32,390,349
Ensembl chr25:32,357,993...32,389,973 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00280 NCBI chr20:38,726,690...38,738,457
Ensembl chr20:38,726,798...38,739,408 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00280 NCBI chr25:59,465,610...59,539,022
Ensembl chr25:59,466,378...59,538,872 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00280 NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00280 NCBI chr  X:129,090,140...129,315,343
Ensembl chr  X:129,088,611...129,312,909 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00280 NCBI chr  X:114,618,397...114,650,827
Ensembl chr  X:114,618,639...114,651,365 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00280 NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00280 NCBI chr 7:101,106,468...101,114,566
Ensembl chr 7:101,106,483...101,114,662 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00280 NCBI chr 7:101,148,457...101,157,245
Ensembl chr 7:101,148,058...101,157,111 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00280 NCBI chr14:21,593,202...21,605,800
Ensembl chr14:21,593,088...21,604,885 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00280 NCBI chr 7:132,143,514...132,173,189
Ensembl chr 7:132,144,420...132,173,187 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00280 NCBI chr 8:40,164,391...40,196,627
Ensembl chr 8:40,163,891...40,196,555 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00280 NCBI chr13:88,266,054...88,321,596
Ensembl chr13:88,268,198...88,322,644 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00280 NCBI chr 5:27,778,553...27,782,639
Ensembl chr 5:27,776,416...27,782,640 		JBrowse link
anistreplase pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00281 NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00281 NCBI chr 3:91,125,097...91,154,000
Ensembl chr 3:91,124,766...91,157,376 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00281 NCBI chr 7:132,180,026...132,207,081
Ensembl chr 7:132,180,336...132,208,155 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00281 NCBI chr23:79,414,074...79,438,896
Ensembl chr23:79,414,225...79,432,298 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00281 NCBI chr17:65,885,498...66,040,026
Ensembl chr17:65,885,658...66,040,040 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00281 NCBI chr25:32,357,540...32,390,349
Ensembl chr25:32,357,993...32,389,973 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00281 NCBI chr20:38,726,690...38,738,457
Ensembl chr20:38,726,798...38,739,408 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00281 NCBI chr25:59,465,610...59,539,022
Ensembl chr25:59,466,378...59,538,872 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00281 NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00281 NCBI chr  X:129,090,140...129,315,343
Ensembl chr  X:129,088,611...129,312,909 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00281 NCBI chr  X:114,618,397...114,650,827
Ensembl chr  X:114,618,639...114,651,365 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00281 NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00281 NCBI chr 7:101,106,468...101,114,566
Ensembl chr 7:101,106,483...101,114,662 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00281 NCBI chr 7:101,148,457...101,157,245
Ensembl chr 7:101,148,058...101,157,111 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00281 NCBI chr14:21,593,202...21,605,800
Ensembl chr14:21,593,088...21,604,885 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00281 NCBI chr 7:132,143,514...132,173,189
Ensembl chr 7:132,144,420...132,173,187 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00281 NCBI chr 8:40,164,391...40,196,627
Ensembl chr 8:40,163,891...40,196,555 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00281 NCBI chr13:88,266,054...88,321,596
Ensembl chr13:88,268,198...88,322,644 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00281 NCBI chr 5:27,778,553...27,782,639
Ensembl chr 5:27,776,416...27,782,640 		JBrowse link
argatroban pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00276 NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00276 NCBI chr 3:91,125,097...91,154,000
Ensembl chr 3:91,124,766...91,157,376 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00276 NCBI chr 7:132,180,026...132,207,081
Ensembl chr 7:132,180,336...132,208,155 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00276 NCBI chr23:79,414,074...79,438,896
Ensembl chr23:79,414,225...79,432,298 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00276 NCBI chr17:65,885,498...66,040,026
Ensembl chr17:65,885,658...66,040,040 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00276 NCBI chr25:32,357,540...32,390,349
Ensembl chr25:32,357,993...32,389,973 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00276 NCBI chr20:38,726,690...38,738,457
Ensembl chr20:38,726,798...38,739,408 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00276 NCBI chr25:59,465,610...59,539,022
Ensembl chr25:59,466,378...59,538,872 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00276 NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00276 NCBI chr  X:129,090,140...129,315,343
Ensembl chr  X:129,088,611...129,312,909 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00276 NCBI chr  X:114,618,397...114,650,827
Ensembl chr  X:114,618,639...114,651,365 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00276 NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00276 NCBI chr 7:101,106,468...101,114,566
Ensembl chr 7:101,106,483...101,114,662 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00276 NCBI chr 7:101,148,457...101,157,245
Ensembl chr 7:101,148,058...101,157,111 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00276 NCBI chr14:21,593,202...21,605,800
Ensembl chr14:21,593,088...21,604,885 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00276 NCBI chr 7:132,143,514...132,173,189
Ensembl chr 7:132,144,420...132,173,187 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00276 NCBI chr 8:40,164,391...40,196,627
Ensembl chr 8:40,163,891...40,196,555 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00276 NCBI chr13:88,266,054...88,321,596
Ensembl chr13:88,268,198...88,322,644 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00276 NCBI chr 5:27,778,553...27,782,639
Ensembl chr 5:27,776,416...27,782,640 		JBrowse link
bivalirudin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00277 NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00277 NCBI chr 3:91,125,097...91,154,000
Ensembl chr 3:91,124,766...91,157,376 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00277 NCBI chr 7:132,180,026...132,207,081
Ensembl chr 7:132,180,336...132,208,155 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00277 NCBI chr23:79,414,074...79,438,896
Ensembl chr23:79,414,225...79,432,298 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00277 NCBI chr17:65,885,498...66,040,026
Ensembl chr17:65,885,658...66,040,040 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00277 NCBI chr25:32,357,540...32,390,349
Ensembl chr25:32,357,993...32,389,973 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00277 NCBI chr20:38,726,690...38,738,457
Ensembl chr20:38,726,798...38,739,408 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00277 NCBI chr25:59,465,610...59,539,022
Ensembl chr25:59,466,378...59,538,872 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00277 NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00277 NCBI chr  X:129,090,140...129,315,343
Ensembl chr  X:129,088,611...129,312,909 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00277 NCBI chr  X:114,618,397...114,650,827
Ensembl chr  X:114,618,639...114,651,365 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00277 NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00277 NCBI chr 7:101,106,468...101,114,566
Ensembl chr 7:101,106,483...101,114,662 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00277 NCBI chr 7:101,148,457...101,157,245
Ensembl chr 7:101,148,058...101,157,111 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00277 NCBI chr14:21,593,202...21,605,800
Ensembl chr14:21,593,088...21,604,885 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00277 NCBI chr 7:132,143,514...132,173,189
Ensembl chr 7:132,144,420...132,173,187 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00277 NCBI chr 8:40,164,391...40,196,627
Ensembl chr 8:40,163,891...40,196,555 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00277 NCBI chr13:88,266,054...88,321,596
Ensembl chr13:88,268,198...88,322,644 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00277 NCBI chr 5:27,778,553...27,782,639
Ensembl chr 5:27,776,416...27,782,640 		JBrowse link
cilostazol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC103221883 uncharacterized LOC103221883 ISO SMPDB SMP:00263 NCBI chr 4:55,148,012...56,665,684
Ensembl chr 4:55,153,563...55,390,027 		JBrowse link
clopidogrel pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 ISO SMPDB SMP:00260 NCBI chr21:61,211,044...61,430,691
Ensembl chr21:61,322,748...61,529,274 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 ISO SMPDB SMP:00260 NCBI chr26:8,727,996...8,733,254 JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 ISO SMPDB SMP:00260 NCBI chr 6:35,392,699...35,418,171
Ensembl chr 6:35,393,342...35,418,106 		JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 ISO SMPDB SMP:00260 NCBI chr 9:87,981,300...88,025,007 JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 ISO SMPDB SMP:00260 NCBI chr 9:88,082,124...88,125,390 JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 ISO SMPDB SMP:00260 NCBI chr28:13,473,649...13,517,905
Ensembl chr28:13,491,483...13,519,507 		JBrowse link
G LOC103246766 cytochrome P450 3A8 ISO SMPDB SMP:00260 NCBI chr28:13,297,566...13,330,023 JBrowse link
G P2RY12 purinergic receptor P2Y12 ISO SMPDB SMP:00260 NCBI chr15:39,315,140...39,361,614
Ensembl chr15:39,359,612...39,360,637 		JBrowse link
G PON1 paraoxonase 1 ISO SMPDB SMP:00260 NCBI chr21:53,713,434...53,739,658
Ensembl chr21:53,714,012...53,739,875 		JBrowse link
clopidogrel pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 ISO SMPDB SMP:00610 NCBI chr21:61,211,044...61,430,691
Ensembl chr21:61,322,748...61,529,274 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 ISO SMPDB SMP:00610 NCBI chr26:8,727,996...8,733,254 JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 ISO SMPDB SMP:00610 NCBI chr 6:35,392,699...35,418,171
Ensembl chr 6:35,393,342...35,418,106 		JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 ISO SMPDB SMP:00610 NCBI chr 9:87,981,300...88,025,007 JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 ISO SMPDB SMP:00610 NCBI chr 9:88,082,124...88,125,390 JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 ISO SMPDB SMP:00610 NCBI chr28:13,473,649...13,517,905
Ensembl chr28:13,491,483...13,519,507 		JBrowse link
G LOC103246766 cytochrome P450 3A8 ISO SMPDB SMP:00610 NCBI chr28:13,297,566...13,330,023 JBrowse link
G P2RY12 purinergic receptor P2Y12 ISO SMPDB SMP:00610 NCBI chr15:39,315,140...39,361,614
Ensembl chr15:39,359,612...39,360,637 		JBrowse link
G PON1 paraoxonase 1 ISO SMPDB SMP:00610 NCBI chr21:53,713,434...53,739,658
Ensembl chr21:53,714,012...53,739,875 		JBrowse link
dicoumarol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00270 SMP:00656 NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00270 SMP:00656 NCBI chr 3:91,125,097...91,154,000
Ensembl chr 3:91,124,766...91,157,376 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00270 SMP:00656 NCBI chr 7:132,180,026...132,207,081
Ensembl chr 7:132,180,336...132,208,155 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00270 SMP:00656 NCBI chr23:79,414,074...79,438,896
Ensembl chr23:79,414,225...79,432,298 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00270 SMP:00656 NCBI chr17:65,885,498...66,040,026
Ensembl chr17:65,885,658...66,040,040 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00270 SMP:00656 NCBI chr25:32,357,540...32,390,349
Ensembl chr25:32,357,993...32,389,973 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00270 SMP:00656 NCBI chr20:38,726,690...38,738,457
Ensembl chr20:38,726,798...38,739,408 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00270 SMP:00656 NCBI chr25:59,465,610...59,539,022
Ensembl chr25:59,466,378...59,538,872 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00270 SMP:00656 NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00270 SMP:00656 NCBI chr  X:129,090,140...129,315,343
Ensembl chr  X:129,088,611...129,312,909 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00270 SMP:00656 NCBI chr  X:114,618,397...114,650,827
Ensembl chr  X:114,618,639...114,651,365 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00270 SMP:00656 NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00270 SMP:00656 NCBI chr 7:101,106,468...101,114,566
Ensembl chr 7:101,106,483...101,114,662 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00270 SMP:00656 NCBI chr 7:101,148,457...101,157,245
Ensembl chr 7:101,148,058...101,157,111 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00270 SMP:00656 NCBI chr14:21,593,202...21,605,800
Ensembl chr14:21,593,088...21,604,885 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00270 SMP:00656 NCBI chr 7:132,143,514...132,173,189
Ensembl chr 7:132,144,420...132,173,187 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00270 SMP:00656 NCBI chr 8:40,164,391...40,196,627
Ensembl chr 8:40,163,891...40,196,555 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00270 SMP:00656 NCBI chr13:88,266,054...88,321,596
Ensembl chr13:88,268,198...88,322,644 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00270 SMP:00656 NCBI chr 5:27,778,553...27,782,639
Ensembl chr 5:27,776,416...27,782,640 		JBrowse link
dipyridamole pharmacodyamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC103221883 uncharacterized LOC103221883 ISO SMPDB SMP:00264 NCBI chr 4:55,148,012...56,665,684
Ensembl chr 4:55,153,563...55,390,027 		JBrowse link
enoxaparin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00272 NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00272 NCBI chr 3:91,125,097...91,154,000
Ensembl chr 3:91,124,766...91,157,376 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00272 NCBI chr 7:132,180,026...132,207,081
Ensembl chr 7:132,180,336...132,208,155 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00272 NCBI chr23:79,414,074...79,438,896
Ensembl chr23:79,414,225...79,432,298 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00272 NCBI chr17:65,885,498...66,040,026
Ensembl chr17:65,885,658...66,040,040 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00272 NCBI chr25:32,357,540...32,390,349
Ensembl chr25:32,357,993...32,389,973 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00272 NCBI chr20:38,726,690...38,738,457
Ensembl chr20:38,726,798...38,739,408 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00272 NCBI chr25:59,465,610...59,539,022
Ensembl chr25:59,466,378...59,538,872 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00272 NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00272 NCBI chr  X:129,090,140...129,315,343
Ensembl chr  X:129,088,611...129,312,909 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00272 NCBI chr  X:114,618,397...114,650,827
Ensembl chr  X:114,618,639...114,651,365 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00272 NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00272 NCBI chr 7:101,106,468...101,114,566
Ensembl chr 7:101,106,483...101,114,662 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00272 NCBI chr 7:101,148,457...101,157,245
Ensembl chr 7:101,148,058...101,157,111 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00272 NCBI chr14:21,593,202...21,605,800
Ensembl chr14:21,593,088...21,604,885 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00272 NCBI chr 7:132,143,514...132,173,189
Ensembl chr 7:132,144,420...132,173,187 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00272 NCBI chr 8:40,164,391...40,196,627
Ensembl chr 8:40,163,891...40,196,555 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00272 NCBI chr13:88,266,054...88,321,596
Ensembl chr13:88,268,198...88,322,644 		JBrowse link
G SERPINC1 serpin family C member 1 ISO SMPDB SMP:00272 NCBI chr25:55,271,823...55,289,855 JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00272 NCBI chr 5:27,778,553...27,782,639
Ensembl chr 5:27,776,416...27,782,640 		JBrowse link
eptifibatide pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGA2B integrin subunit alpha 2b ISO SMPDB SMP:00266 NCBI chr16:62,001,082...62,019,470
Ensembl chr16:62,001,352...62,019,289 		JBrowse link
G ITGB3 integrin subunit beta 3 ISO SMPDB SMP:00266 NCBI chr16:59,372,171...59,431,434
Ensembl chr16:59,374,889...59,410,857 		JBrowse link
fondaparinux pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00273 NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00273 NCBI chr 3:91,125,097...91,154,000
Ensembl chr 3:91,124,766...91,157,376 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00273 NCBI chr 7:132,180,026...132,207,081
Ensembl chr 7:132,180,336...132,208,155 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00273 NCBI chr23:79,414,074...79,438,896
Ensembl chr23:79,414,225...79,432,298 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00273 NCBI chr17:65,885,498...66,040,026
Ensembl chr17:65,885,658...66,040,040 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00273 NCBI chr25:32,357,540...32,390,349
Ensembl chr25:32,357,993...32,389,973 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00273 NCBI chr20:38,726,690...38,738,457
Ensembl chr20:38,726,798...38,739,408 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00273 NCBI chr25:59,465,610...59,539,022
Ensembl chr25:59,466,378...59,538,872 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00273 NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00273 NCBI chr  X:129,090,140...129,315,343
Ensembl chr  X:129,088,611...129,312,909 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00273 NCBI chr  X:114,618,397...114,650,827
Ensembl chr  X:114,618,639...114,651,365 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00273 NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00273 NCBI chr 7:101,106,468...101,114,566
Ensembl chr 7:101,106,483...101,114,662 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00273 NCBI chr 7:101,148,457...101,157,245
Ensembl chr 7:101,148,058...101,157,111 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00273 NCBI chr14:21,593,202...21,605,800
Ensembl chr14:21,593,088...21,604,885 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00273 NCBI chr 7:132,143,514...132,173,189
Ensembl chr 7:132,144,420...132,173,187 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00273 NCBI chr 8:40,164,391...40,196,627
Ensembl chr 8:40,163,891...40,196,555 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00273 NCBI chr13:88,266,054...88,321,596
Ensembl chr13:88,268,198...88,322,644 		JBrowse link
G SERPINC1 serpin family C member 1 ISO SMPDB SMP:00273 NCBI chr25:55,271,823...55,289,855 JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00273 NCBI chr 5:27,778,553...27,782,639
Ensembl chr 5:27,776,416...27,782,640 		JBrowse link
heparin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00274 NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00274 NCBI chr 3:91,125,097...91,154,000
Ensembl chr 3:91,124,766...91,157,376 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00274 NCBI chr 7:132,180,026...132,207,081
Ensembl chr 7:132,180,336...132,208,155 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00274 NCBI chr23:79,414,074...79,438,896
Ensembl chr23:79,414,225...79,432,298 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00274 NCBI chr17:65,885,498...66,040,026
Ensembl chr17:65,885,658...66,040,040 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00274 NCBI chr25:32,357,540...32,390,349
Ensembl chr25:32,357,993...32,389,973 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00274 NCBI chr20:38,726,690...38,738,457
Ensembl chr20:38,726,798...38,739,408 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00274 NCBI chr25:59,465,610...59,539,022
Ensembl chr25:59,466,378...59,538,872 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00274 NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00274 NCBI chr  X:129,090,140...129,315,343
Ensembl chr  X:129,088,611...129,312,909 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00274 NCBI chr  X:114,618,397...114,650,827
Ensembl chr  X:114,618,639...114,651,365 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00274 NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00274 NCBI chr 7:101,106,468...101,114,566
Ensembl chr 7:101,106,483...101,114,662 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00274 NCBI chr 7:101,148,457...101,157,245
Ensembl chr 7:101,148,058...101,157,111 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00274 NCBI chr14:21,593,202...21,605,800
Ensembl chr14:21,593,088...21,604,885 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00274 NCBI chr 7:132,143,514...132,173,189
Ensembl chr 7:132,144,420...132,173,187 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00274 NCBI chr 8:40,164,391...40,196,627
Ensembl chr 8:40,163,891...40,196,555 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00274 NCBI chr13:88,266,054...88,321,596
Ensembl chr13:88,268,198...88,322,644 		JBrowse link
G SERPINC1 serpin family C member 1 ISO SMPDB SMP:00274 NCBI chr25:55,271,823...55,289,855 JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00274 NCBI chr 5:27,778,553...27,782,639
Ensembl chr 5:27,776,416...27,782,640 		JBrowse link
phenindione pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00655 NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00655 NCBI chr 3:91,125,097...91,154,000
Ensembl chr 3:91,124,766...91,157,376 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00655 NCBI chr 7:132,180,026...132,207,081
Ensembl chr 7:132,180,336...132,208,155 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00655 NCBI chr23:79,414,074...79,438,896
Ensembl chr23:79,414,225...79,432,298 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00655 NCBI chr17:65,885,498...66,040,026
Ensembl chr17:65,885,658...66,040,040 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00655 NCBI chr25:32,357,540...32,390,349
Ensembl chr25:32,357,993...32,389,973 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00655 NCBI chr20:38,726,690...38,738,457
Ensembl chr20:38,726,798...38,739,408 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00655 NCBI chr25:59,465,610...59,539,022
Ensembl chr25:59,466,378...59,538,872 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00655 NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00655 NCBI chr  X:129,090,140...129,315,343
Ensembl chr  X:129,088,611...129,312,909 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00655 NCBI chr  X:114,618,397...114,650,827
Ensembl chr  X:114,618,639...114,651,365 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00655 NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00655 NCBI chr 7:101,106,468...101,114,566
Ensembl chr 7:101,106,483...101,114,662 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00655 NCBI chr 7:101,148,457...101,157,245
Ensembl chr 7:101,148,058...101,157,111 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00655 NCBI chr14:21,593,202...21,605,800
Ensembl chr14:21,593,088...21,604,885 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00655 NCBI chr 7:132,143,514...132,173,189
Ensembl chr 7:132,144,420...132,173,187 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00655 NCBI chr 8:40,164,391...40,196,627
Ensembl chr 8:40,163,891...40,196,555 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00655 NCBI chr13:88,266,054...88,321,596
Ensembl chr13:88,268,198...88,322,644 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00655 NCBI chr 5:27,778,553...27,782,639
Ensembl chr 5:27,776,416...27,782,640 		JBrowse link
reteplase pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00285 NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00285 NCBI chr 3:91,125,097...91,154,000
Ensembl chr 3:91,124,766...91,157,376 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00285 NCBI chr 7:132,180,026...132,207,081
Ensembl chr 7:132,180,336...132,208,155 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00285 NCBI chr23:79,414,074...79,438,896
Ensembl chr23:79,414,225...79,432,298 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00285 NCBI chr17:65,885,498...66,040,026
Ensembl chr17:65,885,658...66,040,040 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00285 NCBI chr25:32,357,540...32,390,349
Ensembl chr25:32,357,993...32,389,973 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00285 NCBI chr20:38,726,690...38,738,457
Ensembl chr20:38,726,798...38,739,408 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00285 NCBI chr25:59,465,610...59,539,022
Ensembl chr25:59,466,378...59,538,872 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00285 NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00285 NCBI chr  X:129,090,140...129,315,343
Ensembl chr  X:129,088,611...129,312,909 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00285 NCBI chr  X:114,618,397...114,650,827
Ensembl chr  X:114,618,639...114,651,365 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00285 NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00285 NCBI chr 7:101,106,468...101,114,566
Ensembl chr 7:101,106,483...101,114,662 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00285 NCBI chr 7:101,148,457...101,157,245
Ensembl chr 7:101,148,058...101,157,111 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00285 NCBI chr14:21,593,202...21,605,800
Ensembl chr14:21,593,088...21,604,885 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00285 NCBI chr 7:132,143,514...132,173,189
Ensembl chr 7:132,144,420...132,173,187 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00285 NCBI chr 8:40,164,391...40,196,627
Ensembl chr 8:40,163,891...40,196,555 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00285 NCBI chr13:88,266,054...88,321,596
Ensembl chr13:88,268,198...88,322,644 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00285 NCBI chr 5:27,778,553...27,782,639
Ensembl chr 5:27,776,416...27,782,640 		JBrowse link
salicylic acid pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO SMPDB SMP:00709 NCBI chr16:6,355,795...6,370,051
Ensembl chr16:6,356,058...6,369,738 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00709 NCBI chr16:7,454,950...7,470,949
Ensembl chr16:7,455,044...7,469,934 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00709 NCBI chr16:4,112,795...4,121,764
Ensembl chr16:4,111,151...4,121,645 		JBrowse link
G ALOX15B arachidonate 15-lipoxygenase type B ISO SMPDB SMP:00709 NCBI chr16:7,425,533...7,435,896
Ensembl chr16:7,425,990...7,435,327 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00709 NCBI chr 9:41,085,257...41,145,760
Ensembl chr 9:41,085,361...41,145,331 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 ISO SMPDB SMP:00709 NCBI chr 6:35,392,699...35,418,171
Ensembl chr 6:35,393,342...35,418,106 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 ISO SMPDB SMP:00709 NCBI chr 9:88,154,131...88,183,915
Ensembl chr 9:88,154,134...88,183,458 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO SMPDB SMP:00709 NCBI chr26:53,390,054...53,403,309
Ensembl chr26:53,390,089...53,404,211 		JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 ISO SMPDB SMP:00709 NCBI chr20:73,083,312...73,115,174
Ensembl chr20:73,083,389...73,115,077 		JBrowse link
G CYP2U1 cytochrome P450 family 2 subfamily U member 1 ISO SMPDB SMP:00709 NCBI chr 7:55,859,669...55,880,266
Ensembl chr 7:55,859,849...55,879,280 		JBrowse link
G CYP4F3 cytochrome P450 family 4 subfamily F member 3 ISO SMPDB SMP:00709 NCBI chr 6:14,241,352...14,260,799
Ensembl chr 6:14,241,409...14,263,494 		JBrowse link
G CYP4F8 cytochrome P450 family 4 subfamily F member 8 ISO SMPDB SMP:00709 NCBI chr 6:14,211,899...14,229,793
Ensembl chr 6:14,215,337...14,229,509 		JBrowse link
G EPHX2 epoxide hydrolase 2 ISO SMPDB SMP:00709 NCBI chr 8:25,603,668...25,659,232
Ensembl chr 8:25,603,735...25,659,345 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO SMPDB SMP:00709
G GPX1 glutathione peroxidase 1 ISO SMPDB SMP:00709 NCBI chr22:10,754,976...10,756,617 JBrowse link
G LOC103218526 carbonyl reductase [NADPH] 1 ISO SMPDB SMP:00709 NCBI chr 2:80,096,743...80,099,982 JBrowse link
G LTA4H leukotriene A4 hydrolase ISO SMPDB SMP:00709 NCBI chr11:91,371,383...91,413,396
Ensembl chr11:91,371,383...91,406,542 		JBrowse link
G LTC4S leukotriene C4 synthase ISO SMPDB SMP:00709 NCBI chr23:81,523,784...81,526,297
Ensembl chr23:81,523,775...81,526,179 		JBrowse link
G PLA2G4B phospholipase A2 group IVB ISO SMPDB SMP:00709 NCBI chr26:41,137,643...41,147,384 JBrowse link
G PRXL2B peroxiredoxin like 2B ISO SMPDB SMP:00709 NCBI chr20:128,964,750...128,969,469
Ensembl chr20:128,964,987...128,967,620 		JBrowse link
G PTGDS prostaglandin D2 synthase ISO SMPDB SMP:00709 NCBI chr12:1,210,567...1,214,631
Ensembl chr12:1,211,487...1,214,531 		JBrowse link
G PTGES prostaglandin E synthase ISO SMPDB SMP:00709 NCBI chr12:8,393,462...8,408,441
Ensembl chr12:8,393,550...8,408,435 		JBrowse link
G PTGIS prostaglandin I2 synthase ISO SMPDB SMP:00709 NCBI chr 2:14,420,318...14,484,667
Ensembl chr 2:14,441,983...14,488,264 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00709 NCBI chr12:17,195,403...17,218,450
Ensembl chr12:17,192,628...17,218,315 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00709 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429 		JBrowse link
G TBXAS1 thromboxane A synthase 1 ISO SMPDB SMP:00709 NCBI chr21:108,584,458...108,779,357
Ensembl chr21:108,628,570...108,779,163 		JBrowse link
ticlopidine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2RY12 purinergic receptor P2Y12 ISO SMPDB SMP:00261 NCBI chr15:39,315,140...39,361,614
Ensembl chr15:39,359,612...39,360,637 		JBrowse link
ticlopidine pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2RY12 purinergic receptor P2Y12 ISO SMPDB SMP:00611 NCBI chr15:39,315,140...39,361,614
Ensembl chr15:39,359,612...39,360,637 		JBrowse link
tirofiban pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGA2B integrin subunit alpha 2b ISO SMPDB SMP:00267 NCBI chr16:62,001,082...62,019,470
Ensembl chr16:62,001,352...62,019,289 		JBrowse link
G ITGB3 integrin subunit beta 3 ISO SMPDB SMP:00267 NCBI chr16:59,372,171...59,431,434
Ensembl chr16:59,374,889...59,410,857 		JBrowse link
warfarin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00268 NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00268 NCBI chr 3:91,125,097...91,154,000
Ensembl chr 3:91,124,766...91,157,376 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00268 NCBI chr 7:132,180,026...132,207,081
Ensembl chr 7:132,180,336...132,208,155 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00268 NCBI chr23:79,414,074...79,438,896
Ensembl chr23:79,414,225...79,432,298 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00268 NCBI chr17:65,885,498...66,040,026
Ensembl chr17:65,885,658...66,040,040 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00268 NCBI chr25:32,357,540...32,390,349
Ensembl chr25:32,357,993...32,389,973 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00268 NCBI chr20:38,726,690...38,738,457
Ensembl chr20:38,726,798...38,739,408 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00268 NCBI chr25:59,465,610...59,539,022
Ensembl chr25:59,466,378...59,538,872 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00268 NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00268 NCBI chr  X:129,090,140...129,315,343
Ensembl chr  X:129,088,611...129,312,909 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00268 NCBI chr  X:114,618,397...114,650,827
Ensembl chr  X:114,618,639...114,651,365 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00268 NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00268 NCBI chr 7:101,106,468...101,114,566
Ensembl chr 7:101,106,483...101,114,662 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00268 NCBI chr 7:101,148,457...101,157,245
Ensembl chr 7:101,148,058...101,157,111 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00268 NCBI chr14:21,593,202...21,605,800
Ensembl chr14:21,593,088...21,604,885 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00268 NCBI chr 7:132,143,514...132,173,189
Ensembl chr 7:132,144,420...132,173,187 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00268 NCBI chr 8:40,164,391...40,196,627
Ensembl chr 8:40,163,891...40,196,555 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00268 NCBI chr13:88,266,054...88,321,596
Ensembl chr13:88,268,198...88,322,644 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB
RGD		 PMID:26287237 RGD:11354881 SMP:00268 NCBI chr 5:27,778,553...27,782,639
Ensembl chr 5:27,776,416...27,782,640 		JBrowse link
warfarin pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO RGD PMID:26655108 RGD:11354883 NCBI chr26:8,753,236...8,759,378
Ensembl chr26:8,753,327...8,759,384 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 ISO RGD PMID:26655108 RGD:11354883 NCBI chr26:8,727,996...8,733,254 JBrowse link
G CYP2C18 cytochrome P450 family 2 subfamily C member 18 ISO RGD PMID:26655108 RGD:11354883 NCBI chr 9:87,881,444...87,941,586 JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 ISO RGD PMID:26655108 RGD:11354883 NCBI chr 9:87,981,300...88,025,007 JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 ISO RGD PMID:26655108 RGD:11354883 NCBI chr 9:88,154,131...88,183,915
Ensembl chr 9:88,154,134...88,183,458 		JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 ISO RGD PMID:26655108 RGD:11354883 NCBI chr 9:88,082,124...88,125,390 JBrowse link
G LOC103246766 cytochrome P450 3A8 ISO RGD PMID:26655108 RGD:11354883 NCBI chr28:13,297,566...13,330,023 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4028
    drug pathway 383
      blood and blood forming organs drug pathway 59
        antithrombotic drug pathway 59
          anticoagulant drug pathway + 27
          antiplatelet drug pathway + 37
          other antithrombotic drug pathway + 20
          thrombolytic drug pathway + 19
paths to the root