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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:antithrombotic drug pathway
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Accession:PW:0001651 term browser browse the term
Definition:The pharmacokinetics and pharmacodynamics pathway of drugs that reduce or prevent the formation of blood clots. They are further classified depending on the blood clotting processes they affect. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: anticoagulant drug pathway


show annotations for term's descendants           Sort by:
abciximab pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGA2B integrin subunit alpha 2b ISO SMPDB SMP:00265 NCBI chr 9:19,049,643...19,064,019
Ensembl chr 9:19,050,001...19,063,992 		JBrowse link
G ITGB3 integrin subunit beta 3 ISO SMPDB SMP:00265 NCBI chr 9:9,179,667...9,231,061
Ensembl chr 9:9,182,562...9,231,451 		JBrowse link
acenocoumarol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00269 NCBI chr 9:26,183,852...26,199,927
Ensembl chr 9:26,183,852...26,199,927 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00269 NCBI chr22:60,585,563...60,597,027
Ensembl chr22:60,571,822...60,597,024 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00269 NCBI chr16:44,469,609...44,492,833
Ensembl chr16:44,469,632...44,540,292 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00269 NCBI chr 4:35,950,642...35,968,137
Ensembl chr 4:35,950,695...35,998,025 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00269 NCBI chr35:6,186,750...6,347,522
Ensembl chr35:6,187,235...6,349,773 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00269 NCBI chr 7:5,674,458...5,700,928
Ensembl chr 7:5,674,416...5,700,905 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00269 NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00269 NCBI chr 6:54,709,581...54,720,603
Ensembl chr 6:54,708,471...54,720,607 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00269 NCBI chr 7:28,999,481...29,069,603
Ensembl chr 7:28,999,512...29,069,296 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00269 NCBI chr22:60,572,459...60,582,743
Ensembl chr22:60,571,822...60,597,024 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00269 NCBI chr  X:122,894,974...123,046,343
Ensembl chr  X:122,885,162...123,043,414 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00269 NCBI chr  X:109,501,341...109,533,798
Ensembl chr  X:109,501,341...109,533,798 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00269 NCBI chr15:52,238,305...52,247,017
Ensembl chr15:52,236,198...52,246,975 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00269 NCBI chr15:52,220,690...52,228,526
Ensembl chr15:52,220,611...52,228,250 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00269 NCBI chr15:52,261,215...52,270,077
Ensembl chr15:52,261,217...52,269,964 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00269 NCBI chr17:39,512,293...39,525,251
Ensembl chr17:39,512,387...39,529,121 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00269 NCBI chr16:44,492,735...44,517,854
Ensembl chr16:44,469,632...44,540,292 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00269 NCBI chr16:23,469,590...23,496,013 JBrowse link
G PLG plasminogen ISO SMPDB SMP:00269 NCBI chr 1:49,497,229...49,535,260
Ensembl chr 1:49,497,229...49,535,260 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00269 NCBI chr 6:17,140,565...17,142,621
Ensembl chr 6:17,140,633...17,142,547 		JBrowse link
acetylsalicylic acid pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) ISO SMPDB SMP:00083 NCBI chr 2:30,661,333...30,691,283
Ensembl chr 2:30,674,558...30,690,043 		JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO SMPDB SMP:00083 NCBI chr 5:32,026,193...32,038,698
Ensembl chr 5:31,882,501...32,038,119 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00083 NCBI chr 5:32,899,416...32,911,442
Ensembl chr 5:32,896,238...32,911,552 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00083 NCBI chr 5:31,883,544...31,891,357
Ensembl chr 5:31,882,501...32,038,119 		JBrowse link
G ALOX15B arachidonate 15-lipoxygenase type B ISO SMPDB SMP:00083 NCBI chr 5:32,878,348...32,888,253
Ensembl chr 5:32,878,338...32,888,316 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00083 NCBI chr28:2,170,920...2,218,765
Ensembl chr28:2,170,920...2,219,609 		JBrowse link
G CYP2B6 cytochrome P450 2B11 ISO SMPDB SMP:00083 NCBI chr 1:112,817,561...112,833,294
Ensembl chr 1:112,816,502...112,833,293 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO SMPDB SMP:00083 NCBI chr28:41,079,164...41,089,188
Ensembl chr28:41,035,025...41,122,754 		JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 ISO SMPDB SMP:00083 NCBI chr 5:49,942,241...49,986,603
Ensembl chr 5:49,942,193...49,984,617 		JBrowse link
G CYP2U1 cytochrome P450 family 2 subfamily U member 1 ISO SMPDB SMP:00083 NCBI chr32:28,426,250...28,445,399
Ensembl chr32:28,438,173...28,444,383 		JBrowse link
G EPHX2 epoxide hydrolase 2 ISO SMPDB SMP:00083 NCBI chr25:30,045,040...30,107,110
Ensembl chr25:30,045,291...30,107,110 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO SMPDB SMP:00083 NCBI chr26:28,301,455...28,315,029 JBrowse link
G GPX1 glutathione peroxidase 1 ISO SMPDB SMP:00083 NCBI chr20:39,889,165...39,890,253
Ensembl chr20:39,889,174...39,890,260 		JBrowse link
G LOC484867 cytochrome P450 4F3 ISO SMPDB SMP:00083 NCBI chr20:46,611,799...46,664,131
Ensembl chr20:46,458,620...46,705,789 		JBrowse link
G LOC610164 carbonyl reductase [NADPH] 1 ISO SMPDB SMP:00083 NCBI chr31:31,316,573...31,321,413 JBrowse link
G LTA4H leukotriene A4 hydrolase ISO SMPDB SMP:00083 NCBI chr15:35,795,934...35,830,681
Ensembl chr15:35,795,979...35,830,844 		JBrowse link
G LTC4S leukotriene C4 synthase ISO SMPDB SMP:00083 NCBI chr11:1,893,927...1,897,028
Ensembl chr11:1,894,380...1,897,752 		JBrowse link
G PLA2G4B phospholipase A2 group IVB ISO SMPDB SMP:00083 NCBI chr30:8,865,941...8,878,687
Ensembl chr30:8,859,257...8,876,395 		JBrowse link
G PRXL2B peroxiredoxin like 2B ISO SMPDB SMP:00083 NCBI chr 5:57,429,973...57,434,371
Ensembl chr 5:57,429,212...57,434,210 		JBrowse link
G PTGDS prostaglandin D2 synthase ISO SMPDB SMP:00083 NCBI chr 9:48,647,334...48,650,608
Ensembl chr 9:48,646,255...48,669,814 		JBrowse link
G PTGES prostaglandin E synthase ISO SMPDB SMP:00083 NCBI chr 9:54,071,472...54,082,232
Ensembl chr 9:54,071,472...54,082,232 		JBrowse link
G PTGIS prostaglandin I2 synthase ISO SMPDB SMP:00083 NCBI chr24:36,129,091...36,162,525
Ensembl chr24:36,132,173...36,162,509 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00083 NCBI chr 9:60,195,118...60,216,847
Ensembl chr 9:60,195,124...60,216,819 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00083 NCBI chr 7:19,668,079...19,674,903
Ensembl chr 7:19,668,082...19,674,903 		JBrowse link
G TBXAS1 thromboxane A synthase 1 ISO SMPDB SMP:00083 NCBI chr16:8,870,283...9,032,105
Ensembl chr16:8,870,284...9,023,462 		JBrowse link
alteplase pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00280 NCBI chr 9:26,183,852...26,199,927
Ensembl chr 9:26,183,852...26,199,927 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00280 NCBI chr22:60,585,563...60,597,027
Ensembl chr22:60,571,822...60,597,024 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00280 NCBI chr16:44,469,609...44,492,833
Ensembl chr16:44,469,632...44,540,292 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00280 NCBI chr 4:35,950,642...35,968,137
Ensembl chr 4:35,950,695...35,998,025 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00280 NCBI chr35:6,186,750...6,347,522
Ensembl chr35:6,187,235...6,349,773 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00280 NCBI chr 7:5,674,458...5,700,928
Ensembl chr 7:5,674,416...5,700,905 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00280 NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00280 NCBI chr 6:54,709,581...54,720,603
Ensembl chr 6:54,708,471...54,720,607 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00280 NCBI chr 7:28,999,481...29,069,603
Ensembl chr 7:28,999,512...29,069,296 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00280 NCBI chr22:60,572,459...60,582,743
Ensembl chr22:60,571,822...60,597,024 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00280 NCBI chr  X:122,894,974...123,046,343
Ensembl chr  X:122,885,162...123,043,414 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00280 NCBI chr  X:109,501,341...109,533,798
Ensembl chr  X:109,501,341...109,533,798 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00280 NCBI chr15:52,238,305...52,247,017
Ensembl chr15:52,236,198...52,246,975 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00280 NCBI chr15:52,220,690...52,228,526
Ensembl chr15:52,220,611...52,228,250 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00280 NCBI chr15:52,261,215...52,270,077
Ensembl chr15:52,261,217...52,269,964 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00280 NCBI chr17:39,512,293...39,525,251
Ensembl chr17:39,512,387...39,529,121 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00280 NCBI chr16:44,492,735...44,517,854
Ensembl chr16:44,469,632...44,540,292 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00280 NCBI chr16:23,469,590...23,496,013 JBrowse link
G PLG plasminogen ISO SMPDB SMP:00280 NCBI chr 1:49,497,229...49,535,260
Ensembl chr 1:49,497,229...49,535,260 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00280 NCBI chr 6:17,140,565...17,142,621
Ensembl chr 6:17,140,633...17,142,547 		JBrowse link
anistreplase pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00281 NCBI chr 9:26,183,852...26,199,927
Ensembl chr 9:26,183,852...26,199,927 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00281 NCBI chr22:60,585,563...60,597,027
Ensembl chr22:60,571,822...60,597,024 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00281 NCBI chr16:44,469,609...44,492,833
Ensembl chr16:44,469,632...44,540,292 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00281 NCBI chr 4:35,950,642...35,968,137
Ensembl chr 4:35,950,695...35,998,025 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00281 NCBI chr35:6,186,750...6,347,522
Ensembl chr35:6,187,235...6,349,773 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00281 NCBI chr 7:5,674,458...5,700,928
Ensembl chr 7:5,674,416...5,700,905 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00281 NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00281 NCBI chr 6:54,709,581...54,720,603
Ensembl chr 6:54,708,471...54,720,607 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00281 NCBI chr 7:28,999,481...29,069,603
Ensembl chr 7:28,999,512...29,069,296 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00281 NCBI chr22:60,572,459...60,582,743
Ensembl chr22:60,571,822...60,597,024 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00281 NCBI chr  X:122,894,974...123,046,343
Ensembl chr  X:122,885,162...123,043,414 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00281 NCBI chr  X:109,501,341...109,533,798
Ensembl chr  X:109,501,341...109,533,798 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00281 NCBI chr15:52,238,305...52,247,017
Ensembl chr15:52,236,198...52,246,975 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00281 NCBI chr15:52,220,690...52,228,526
Ensembl chr15:52,220,611...52,228,250 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00281 NCBI chr15:52,261,215...52,270,077
Ensembl chr15:52,261,217...52,269,964 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00281 NCBI chr17:39,512,293...39,525,251
Ensembl chr17:39,512,387...39,529,121 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00281 NCBI chr16:44,492,735...44,517,854
Ensembl chr16:44,469,632...44,540,292 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00281 NCBI chr16:23,469,590...23,496,013 JBrowse link
G PLG plasminogen ISO SMPDB SMP:00281 NCBI chr 1:49,497,229...49,535,260
Ensembl chr 1:49,497,229...49,535,260 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00281 NCBI chr 6:17,140,565...17,142,621
Ensembl chr 6:17,140,633...17,142,547 		JBrowse link
argatroban pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00276 NCBI chr 9:26,183,852...26,199,927
Ensembl chr 9:26,183,852...26,199,927 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00276 NCBI chr22:60,585,563...60,597,027
Ensembl chr22:60,571,822...60,597,024 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00276 NCBI chr16:44,469,609...44,492,833
Ensembl chr16:44,469,632...44,540,292 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00276 NCBI chr 4:35,950,642...35,968,137
Ensembl chr 4:35,950,695...35,998,025 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00276 NCBI chr35:6,186,750...6,347,522
Ensembl chr35:6,187,235...6,349,773 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00276 NCBI chr 7:5,674,458...5,700,928
Ensembl chr 7:5,674,416...5,700,905 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00276 NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00276 NCBI chr 6:54,709,581...54,720,603
Ensembl chr 6:54,708,471...54,720,607 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00276 NCBI chr 7:28,999,481...29,069,603
Ensembl chr 7:28,999,512...29,069,296 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00276 NCBI chr22:60,572,459...60,582,743
Ensembl chr22:60,571,822...60,597,024 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00276 NCBI chr  X:122,894,974...123,046,343
Ensembl chr  X:122,885,162...123,043,414 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00276 NCBI chr  X:109,501,341...109,533,798
Ensembl chr  X:109,501,341...109,533,798 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00276 NCBI chr15:52,238,305...52,247,017
Ensembl chr15:52,236,198...52,246,975 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00276 NCBI chr15:52,220,690...52,228,526
Ensembl chr15:52,220,611...52,228,250 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00276 NCBI chr15:52,261,215...52,270,077
Ensembl chr15:52,261,217...52,269,964 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00276 NCBI chr17:39,512,293...39,525,251
Ensembl chr17:39,512,387...39,529,121 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00276 NCBI chr16:44,492,735...44,517,854
Ensembl chr16:44,469,632...44,540,292 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00276 NCBI chr16:23,469,590...23,496,013 JBrowse link
G PLG plasminogen ISO SMPDB SMP:00276 NCBI chr 1:49,497,229...49,535,260
Ensembl chr 1:49,497,229...49,535,260 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00276 NCBI chr 6:17,140,565...17,142,621
Ensembl chr 6:17,140,633...17,142,547 		JBrowse link
bivalirudin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00277 NCBI chr 9:26,183,852...26,199,927
Ensembl chr 9:26,183,852...26,199,927 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00277 NCBI chr22:60,585,563...60,597,027
Ensembl chr22:60,571,822...60,597,024 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00277 NCBI chr16:44,469,609...44,492,833
Ensembl chr16:44,469,632...44,540,292 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00277 NCBI chr 4:35,950,642...35,968,137
Ensembl chr 4:35,950,695...35,998,025 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00277 NCBI chr35:6,186,750...6,347,522
Ensembl chr35:6,187,235...6,349,773 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00277 NCBI chr 7:5,674,458...5,700,928
Ensembl chr 7:5,674,416...5,700,905 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00277 NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00277 NCBI chr 6:54,709,581...54,720,603
Ensembl chr 6:54,708,471...54,720,607 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00277 NCBI chr 7:28,999,481...29,069,603
Ensembl chr 7:28,999,512...29,069,296 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00277 NCBI chr22:60,572,459...60,582,743
Ensembl chr22:60,571,822...60,597,024 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00277 NCBI chr  X:122,894,974...123,046,343
Ensembl chr  X:122,885,162...123,043,414 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00277 NCBI chr  X:109,501,341...109,533,798
Ensembl chr  X:109,501,341...109,533,798 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00277 NCBI chr15:52,238,305...52,247,017
Ensembl chr15:52,236,198...52,246,975 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00277 NCBI chr15:52,220,690...52,228,526
Ensembl chr15:52,220,611...52,228,250 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00277 NCBI chr15:52,261,215...52,270,077
Ensembl chr15:52,261,217...52,269,964 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00277 NCBI chr17:39,512,293...39,525,251
Ensembl chr17:39,512,387...39,529,121 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00277 NCBI chr16:44,492,735...44,517,854
Ensembl chr16:44,469,632...44,540,292 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00277 NCBI chr16:23,469,590...23,496,013 JBrowse link
G PLG plasminogen ISO SMPDB SMP:00277 NCBI chr 1:49,497,229...49,535,260
Ensembl chr 1:49,497,229...49,535,260 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00277 NCBI chr 6:17,140,565...17,142,621
Ensembl chr 6:17,140,633...17,142,547 		JBrowse link
cilostazol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDE4D phosphodiesterase 4D ISO SMPDB SMP:00263 NCBI chr 2:45,843,767...47,245,263
Ensembl chr 2:45,846,294...46,949,912 		JBrowse link
clopidogrel pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 ISO SMPDB SMP:00260 NCBI chr14:13,644,891...13,852,829
Ensembl chr14:13,542,647...13,742,727 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 ISO SMPDB SMP:00260 NCBI chr30:37,818,400...37,824,192
Ensembl chr30:37,799,140...37,824,135 		JBrowse link
G CYP2B6 cytochrome P450 2B11 ISO SMPDB SMP:00260 NCBI chr 1:112,817,561...112,833,294
Ensembl chr 1:112,816,502...112,833,293 		JBrowse link
G CYP2C41 cytochrome P450 2C41 ISO SMPDB SMP:00260
G CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 ISO SMPDB SMP:00260 NCBI chr 6:9,836,685...9,869,520
Ensembl chr 6:9,777,659...9,869,352 		JBrowse link
G P2RY12 purinergic receptor P2Y12 ISO SMPDB SMP:00260 NCBI chr23:45,908,574...45,954,675
Ensembl chr23:45,909,485...45,910,526 		JBrowse link
G PON1 paraoxonase 1 ISO SMPDB SMP:00260 NCBI chr14:20,565,620...20,600,774
Ensembl chr14:20,565,641...20,642,985 		JBrowse link
clopidogrel pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 ISO SMPDB SMP:00610 NCBI chr14:13,644,891...13,852,829
Ensembl chr14:13,542,647...13,742,727 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 ISO SMPDB SMP:00610 NCBI chr30:37,818,400...37,824,192
Ensembl chr30:37,799,140...37,824,135 		JBrowse link
G CYP2B6 cytochrome P450 2B11 ISO SMPDB SMP:00610 NCBI chr 1:112,817,561...112,833,294
Ensembl chr 1:112,816,502...112,833,293 		JBrowse link
G CYP2C41 cytochrome P450 2C41 ISO SMPDB SMP:00610
G CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 ISO SMPDB SMP:00610 NCBI chr 6:9,836,685...9,869,520
Ensembl chr 6:9,777,659...9,869,352 		JBrowse link
G P2RY12 purinergic receptor P2Y12 ISO SMPDB SMP:00610 NCBI chr23:45,908,574...45,954,675
Ensembl chr23:45,909,485...45,910,526 		JBrowse link
G PON1 paraoxonase 1 ISO SMPDB SMP:00610 NCBI chr14:20,565,620...20,600,774
Ensembl chr14:20,565,641...20,642,985 		JBrowse link
dicoumarol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00270 SMP:00656 NCBI chr 9:26,183,852...26,199,927
Ensembl chr 9:26,183,852...26,199,927 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00270 SMP:00656 NCBI chr22:60,585,563...60,597,027
Ensembl chr22:60,571,822...60,597,024 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00270 SMP:00656 NCBI chr16:44,469,609...44,492,833
Ensembl chr16:44,469,632...44,540,292 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00270 SMP:00656 NCBI chr 4:35,950,642...35,968,137
Ensembl chr 4:35,950,695...35,998,025 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00270 SMP:00656 NCBI chr35:6,186,750...6,347,522
Ensembl chr35:6,187,235...6,349,773 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00270 SMP:00656 NCBI chr 7:5,674,458...5,700,928
Ensembl chr 7:5,674,416...5,700,905 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00270 SMP:00656 NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00270 SMP:00656 NCBI chr 6:54,709,581...54,720,603
Ensembl chr 6:54,708,471...54,720,607 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00270 SMP:00656 NCBI chr 7:28,999,481...29,069,603
Ensembl chr 7:28,999,512...29,069,296 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00270 SMP:00656 NCBI chr22:60,572,459...60,582,743
Ensembl chr22:60,571,822...60,597,024 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00270 SMP:00656 NCBI chr  X:122,894,974...123,046,343
Ensembl chr  X:122,885,162...123,043,414 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00270 SMP:00656 NCBI chr  X:109,501,341...109,533,798
Ensembl chr  X:109,501,341...109,533,798 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00270 SMP:00656 NCBI chr15:52,238,305...52,247,017
Ensembl chr15:52,236,198...52,246,975 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00270 SMP:00656 NCBI chr15:52,220,690...52,228,526
Ensembl chr15:52,220,611...52,228,250 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00270 SMP:00656 NCBI chr15:52,261,215...52,270,077
Ensembl chr15:52,261,217...52,269,964 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00270 SMP:00656 NCBI chr17:39,512,293...39,525,251
Ensembl chr17:39,512,387...39,529,121 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00270 SMP:00656 NCBI chr16:44,492,735...44,517,854
Ensembl chr16:44,469,632...44,540,292 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00270 SMP:00656 NCBI chr16:23,469,590...23,496,013 JBrowse link
G PLG plasminogen ISO SMPDB SMP:00270 SMP:00656 NCBI chr 1:49,497,229...49,535,260
Ensembl chr 1:49,497,229...49,535,260 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00270 SMP:00656 NCBI chr 6:17,140,565...17,142,621
Ensembl chr 6:17,140,633...17,142,547 		JBrowse link
dipyridamole pharmacodyamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDE4D phosphodiesterase 4D ISO SMPDB SMP:00264 NCBI chr 2:45,843,767...47,245,263
Ensembl chr 2:45,846,294...46,949,912 		JBrowse link
enoxaparin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00272 NCBI chr 9:26,183,852...26,199,927
Ensembl chr 9:26,183,852...26,199,927 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00272 NCBI chr22:60,585,563...60,597,027
Ensembl chr22:60,571,822...60,597,024 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00272 NCBI chr16:44,469,609...44,492,833
Ensembl chr16:44,469,632...44,540,292 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00272 NCBI chr 4:35,950,642...35,968,137
Ensembl chr 4:35,950,695...35,998,025 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00272 NCBI chr35:6,186,750...6,347,522
Ensembl chr35:6,187,235...6,349,773 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00272 NCBI chr 7:5,674,458...5,700,928
Ensembl chr 7:5,674,416...5,700,905 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00272 NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00272 NCBI chr 6:54,709,581...54,720,603
Ensembl chr 6:54,708,471...54,720,607 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00272 NCBI chr 7:28,999,481...29,069,603
Ensembl chr 7:28,999,512...29,069,296 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00272 NCBI chr22:60,572,459...60,582,743
Ensembl chr22:60,571,822...60,597,024 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00272 NCBI chr  X:122,894,974...123,046,343
Ensembl chr  X:122,885,162...123,043,414 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00272 NCBI chr  X:109,501,341...109,533,798
Ensembl chr  X:109,501,341...109,533,798 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00272 NCBI chr15:52,238,305...52,247,017
Ensembl chr15:52,236,198...52,246,975 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00272 NCBI chr15:52,220,690...52,228,526
Ensembl chr15:52,220,611...52,228,250 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00272 NCBI chr15:52,261,215...52,270,077
Ensembl chr15:52,261,217...52,269,964 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00272 NCBI chr17:39,512,293...39,525,251
Ensembl chr17:39,512,387...39,529,121 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00272 NCBI chr16:44,492,735...44,517,854
Ensembl chr16:44,469,632...44,540,292 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00272 NCBI chr16:23,469,590...23,496,013 JBrowse link
G PLG plasminogen ISO SMPDB SMP:00272 NCBI chr 1:49,497,229...49,535,260
Ensembl chr 1:49,497,229...49,535,260 		JBrowse link
G SERPINC1 serpin family C member 1 ISO SMPDB SMP:00272 NCBI chr 7:25,322,668...25,333,022
Ensembl chr 7:25,316,129...25,332,987 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00272 NCBI chr 6:17,140,565...17,142,621
Ensembl chr 6:17,140,633...17,142,547 		JBrowse link
eptifibatide pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGA2B integrin subunit alpha 2b ISO SMPDB SMP:00266 NCBI chr 9:19,049,643...19,064,019
Ensembl chr 9:19,050,001...19,063,992 		JBrowse link
G ITGB3 integrin subunit beta 3 ISO SMPDB SMP:00266 NCBI chr 9:9,179,667...9,231,061
Ensembl chr 9:9,182,562...9,231,451 		JBrowse link
fondaparinux pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00273 NCBI chr 9:26,183,852...26,199,927
Ensembl chr 9:26,183,852...26,199,927 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00273 NCBI chr22:60,585,563...60,597,027
Ensembl chr22:60,571,822...60,597,024 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00273 NCBI chr16:44,469,609...44,492,833
Ensembl chr16:44,469,632...44,540,292 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00273 NCBI chr 4:35,950,642...35,968,137
Ensembl chr 4:35,950,695...35,998,025 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00273 NCBI chr35:6,186,750...6,347,522
Ensembl chr35:6,187,235...6,349,773 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00273 NCBI chr 7:5,674,458...5,700,928
Ensembl chr 7:5,674,416...5,700,905 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00273 NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00273 NCBI chr 6:54,709,581...54,720,603
Ensembl chr 6:54,708,471...54,720,607 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00273 NCBI chr 7:28,999,481...29,069,603
Ensembl chr 7:28,999,512...29,069,296 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00273 NCBI chr22:60,572,459...60,582,743
Ensembl chr22:60,571,822...60,597,024 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00273 NCBI chr  X:122,894,974...123,046,343
Ensembl chr  X:122,885,162...123,043,414 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00273 NCBI chr  X:109,501,341...109,533,798
Ensembl chr  X:109,501,341...109,533,798 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00273 NCBI chr15:52,238,305...52,247,017
Ensembl chr15:52,236,198...52,246,975 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00273 NCBI chr15:52,220,690...52,228,526
Ensembl chr15:52,220,611...52,228,250 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00273 NCBI chr15:52,261,215...52,270,077
Ensembl chr15:52,261,217...52,269,964 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00273 NCBI chr17:39,512,293...39,525,251
Ensembl chr17:39,512,387...39,529,121 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00273 NCBI chr16:44,492,735...44,517,854
Ensembl chr16:44,469,632...44,540,292 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00273 NCBI chr16:23,469,590...23,496,013 JBrowse link
G PLG plasminogen ISO SMPDB SMP:00273 NCBI chr 1:49,497,229...49,535,260
Ensembl chr 1:49,497,229...49,535,260 		JBrowse link
G SERPINC1 serpin family C member 1 ISO SMPDB SMP:00273 NCBI chr 7:25,322,668...25,333,022
Ensembl chr 7:25,316,129...25,332,987 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00273 NCBI chr 6:17,140,565...17,142,621
Ensembl chr 6:17,140,633...17,142,547 		JBrowse link
heparin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00274 NCBI chr 9:26,183,852...26,199,927
Ensembl chr 9:26,183,852...26,199,927 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00274 NCBI chr22:60,585,563...60,597,027
Ensembl chr22:60,571,822...60,597,024 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00274 NCBI chr16:44,469,609...44,492,833
Ensembl chr16:44,469,632...44,540,292 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00274 NCBI chr 4:35,950,642...35,968,137
Ensembl chr 4:35,950,695...35,998,025 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00274 NCBI chr35:6,186,750...6,347,522
Ensembl chr35:6,187,235...6,349,773 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00274 NCBI chr 7:5,674,458...5,700,928
Ensembl chr 7:5,674,416...5,700,905 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00274 NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00274 NCBI chr 6:54,709,581...54,720,603
Ensembl chr 6:54,708,471...54,720,607 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00274 NCBI chr 7:28,999,481...29,069,603
Ensembl chr 7:28,999,512...29,069,296 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00274 NCBI chr22:60,572,459...60,582,743
Ensembl chr22:60,571,822...60,597,024 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00274 NCBI chr  X:122,894,974...123,046,343
Ensembl chr  X:122,885,162...123,043,414 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00274 NCBI chr  X:109,501,341...109,533,798
Ensembl chr  X:109,501,341...109,533,798 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00274 NCBI chr15:52,238,305...52,247,017
Ensembl chr15:52,236,198...52,246,975 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00274 NCBI chr15:52,220,690...52,228,526
Ensembl chr15:52,220,611...52,228,250 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00274 NCBI chr15:52,261,215...52,270,077
Ensembl chr15:52,261,217...52,269,964 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00274 NCBI chr17:39,512,293...39,525,251
Ensembl chr17:39,512,387...39,529,121 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00274 NCBI chr16:44,492,735...44,517,854
Ensembl chr16:44,469,632...44,540,292 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00274 NCBI chr16:23,469,590...23,496,013 JBrowse link
G PLG plasminogen ISO SMPDB SMP:00274 NCBI chr 1:49,497,229...49,535,260
Ensembl chr 1:49,497,229...49,535,260 		JBrowse link
G SERPINC1 serpin family C member 1 ISO SMPDB SMP:00274 NCBI chr 7:25,322,668...25,333,022
Ensembl chr 7:25,316,129...25,332,987 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00274 NCBI chr 6:17,140,565...17,142,621
Ensembl chr 6:17,140,633...17,142,547 		JBrowse link
phenindione pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00655 NCBI chr 9:26,183,852...26,199,927
Ensembl chr 9:26,183,852...26,199,927 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00655 NCBI chr22:60,585,563...60,597,027
Ensembl chr22:60,571,822...60,597,024 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00655 NCBI chr16:44,469,609...44,492,833
Ensembl chr16:44,469,632...44,540,292 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00655 NCBI chr 4:35,950,642...35,968,137
Ensembl chr 4:35,950,695...35,998,025 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00655 NCBI chr35:6,186,750...6,347,522
Ensembl chr35:6,187,235...6,349,773 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00655 NCBI chr 7:5,674,458...5,700,928
Ensembl chr 7:5,674,416...5,700,905 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00655 NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00655 NCBI chr 6:54,709,581...54,720,603
Ensembl chr 6:54,708,471...54,720,607 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00655 NCBI chr 7:28,999,481...29,069,603
Ensembl chr 7:28,999,512...29,069,296 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00655 NCBI chr22:60,572,459...60,582,743
Ensembl chr22:60,571,822...60,597,024 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00655 NCBI chr  X:122,894,974...123,046,343
Ensembl chr  X:122,885,162...123,043,414 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00655 NCBI chr  X:109,501,341...109,533,798
Ensembl chr  X:109,501,341...109,533,798 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00655 NCBI chr15:52,238,305...52,247,017
Ensembl chr15:52,236,198...52,246,975 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00655 NCBI chr15:52,220,690...52,228,526
Ensembl chr15:52,220,611...52,228,250 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00655 NCBI chr15:52,261,215...52,270,077
Ensembl chr15:52,261,217...52,269,964 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00655 NCBI chr17:39,512,293...39,525,251
Ensembl chr17:39,512,387...39,529,121 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00655 NCBI chr16:44,492,735...44,517,854
Ensembl chr16:44,469,632...44,540,292 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00655 NCBI chr16:23,469,590...23,496,013 JBrowse link
G PLG plasminogen ISO SMPDB SMP:00655 NCBI chr 1:49,497,229...49,535,260
Ensembl chr 1:49,497,229...49,535,260 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00655 NCBI chr 6:17,140,565...17,142,621
Ensembl chr 6:17,140,633...17,142,547 		JBrowse link
reteplase pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00285 NCBI chr 9:26,183,852...26,199,927
Ensembl chr 9:26,183,852...26,199,927 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00285 NCBI chr22:60,585,563...60,597,027
Ensembl chr22:60,571,822...60,597,024 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00285 NCBI chr16:44,469,609...44,492,833
Ensembl chr16:44,469,632...44,540,292 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00285 NCBI chr 4:35,950,642...35,968,137
Ensembl chr 4:35,950,695...35,998,025 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00285 NCBI chr35:6,186,750...6,347,522
Ensembl chr35:6,187,235...6,349,773 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00285 NCBI chr 7:5,674,458...5,700,928
Ensembl chr 7:5,674,416...5,700,905 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00285 NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00285 NCBI chr 6:54,709,581...54,720,603
Ensembl chr 6:54,708,471...54,720,607 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00285 NCBI chr 7:28,999,481...29,069,603
Ensembl chr 7:28,999,512...29,069,296 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00285 NCBI chr22:60,572,459...60,582,743
Ensembl chr22:60,571,822...60,597,024 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00285 NCBI chr  X:122,894,974...123,046,343
Ensembl chr  X:122,885,162...123,043,414 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00285 NCBI chr  X:109,501,341...109,533,798
Ensembl chr  X:109,501,341...109,533,798 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00285 NCBI chr15:52,238,305...52,247,017
Ensembl chr15:52,236,198...52,246,975 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00285 NCBI chr15:52,220,690...52,228,526
Ensembl chr15:52,220,611...52,228,250 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00285 NCBI chr15:52,261,215...52,270,077
Ensembl chr15:52,261,217...52,269,964 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00285 NCBI chr17:39,512,293...39,525,251
Ensembl chr17:39,512,387...39,529,121 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00285 NCBI chr16:44,492,735...44,517,854
Ensembl chr16:44,469,632...44,540,292 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00285 NCBI chr16:23,469,590...23,496,013 JBrowse link
G PLG plasminogen ISO SMPDB SMP:00285 NCBI chr 1:49,497,229...49,535,260
Ensembl chr 1:49,497,229...49,535,260 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00285 NCBI chr 6:17,140,565...17,142,621
Ensembl chr 6:17,140,633...17,142,547 		JBrowse link
salicylic acid pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) ISO SMPDB SMP:00709 NCBI chr 2:30,661,333...30,691,283
Ensembl chr 2:30,674,558...30,690,043 		JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO SMPDB SMP:00709 NCBI chr 5:32,026,193...32,038,698
Ensembl chr 5:31,882,501...32,038,119 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00709 NCBI chr 5:32,899,416...32,911,442
Ensembl chr 5:32,896,238...32,911,552 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00709 NCBI chr 5:31,883,544...31,891,357
Ensembl chr 5:31,882,501...32,038,119 		JBrowse link
G ALOX15B arachidonate 15-lipoxygenase type B ISO SMPDB SMP:00709 NCBI chr 5:32,878,348...32,888,253
Ensembl chr 5:32,878,338...32,888,316 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00709 NCBI chr28:2,170,920...2,218,765
Ensembl chr28:2,170,920...2,219,609 		JBrowse link
G CYP2B6 cytochrome P450 2B11 ISO SMPDB SMP:00709 NCBI chr 1:112,817,561...112,833,294
Ensembl chr 1:112,816,502...112,833,293 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO SMPDB SMP:00709 NCBI chr28:41,079,164...41,089,188
Ensembl chr28:41,035,025...41,122,754 		JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 ISO SMPDB SMP:00709 NCBI chr 5:49,942,241...49,986,603
Ensembl chr 5:49,942,193...49,984,617 		JBrowse link
G CYP2U1 cytochrome P450 family 2 subfamily U member 1 ISO SMPDB SMP:00709 NCBI chr32:28,426,250...28,445,399
Ensembl chr32:28,438,173...28,444,383 		JBrowse link
G EPHX2 epoxide hydrolase 2 ISO SMPDB SMP:00709 NCBI chr25:30,045,040...30,107,110
Ensembl chr25:30,045,291...30,107,110 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO SMPDB SMP:00709 NCBI chr26:28,301,455...28,315,029 JBrowse link
G GPX1 glutathione peroxidase 1 ISO SMPDB SMP:00709 NCBI chr20:39,889,165...39,890,253
Ensembl chr20:39,889,174...39,890,260 		JBrowse link
G LOC484867 cytochrome P450 4F3 ISO SMPDB SMP:00709 NCBI chr20:46,611,799...46,664,131
Ensembl chr20:46,458,620...46,705,789 		JBrowse link
G LOC610164 carbonyl reductase [NADPH] 1 ISO SMPDB SMP:00709 NCBI chr31:31,316,573...31,321,413 JBrowse link
G LTA4H leukotriene A4 hydrolase ISO SMPDB SMP:00709 NCBI chr15:35,795,934...35,830,681
Ensembl chr15:35,795,979...35,830,844 		JBrowse link
G LTC4S leukotriene C4 synthase ISO SMPDB SMP:00709 NCBI chr11:1,893,927...1,897,028
Ensembl chr11:1,894,380...1,897,752 		JBrowse link
G PLA2G4B phospholipase A2 group IVB ISO SMPDB SMP:00709 NCBI chr30:8,865,941...8,878,687
Ensembl chr30:8,859,257...8,876,395 		JBrowse link
G PRXL2B peroxiredoxin like 2B ISO SMPDB SMP:00709 NCBI chr 5:57,429,973...57,434,371
Ensembl chr 5:57,429,212...57,434,210 		JBrowse link
G PTGDS prostaglandin D2 synthase ISO SMPDB SMP:00709 NCBI chr 9:48,647,334...48,650,608
Ensembl chr 9:48,646,255...48,669,814 		JBrowse link
G PTGES prostaglandin E synthase ISO SMPDB SMP:00709 NCBI chr 9:54,071,472...54,082,232
Ensembl chr 9:54,071,472...54,082,232 		JBrowse link
G PTGIS prostaglandin I2 synthase ISO SMPDB SMP:00709 NCBI chr24:36,129,091...36,162,525
Ensembl chr24:36,132,173...36,162,509 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00709 NCBI chr 9:60,195,118...60,216,847
Ensembl chr 9:60,195,124...60,216,819 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00709 NCBI chr 7:19,668,079...19,674,903
Ensembl chr 7:19,668,082...19,674,903 		JBrowse link
G TBXAS1 thromboxane A synthase 1 ISO SMPDB SMP:00709 NCBI chr16:8,870,283...9,032,105
Ensembl chr16:8,870,284...9,023,462 		JBrowse link
ticlopidine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2RY12 purinergic receptor P2Y12 ISO SMPDB SMP:00261 NCBI chr23:45,908,574...45,954,675
Ensembl chr23:45,909,485...45,910,526 		JBrowse link
ticlopidine pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2RY12 purinergic receptor P2Y12 ISO SMPDB SMP:00611 NCBI chr23:45,908,574...45,954,675
Ensembl chr23:45,909,485...45,910,526 		JBrowse link
tirofiban pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGA2B integrin subunit alpha 2b ISO SMPDB SMP:00267 NCBI chr 9:19,049,643...19,064,019
Ensembl chr 9:19,050,001...19,063,992 		JBrowse link
G ITGB3 integrin subunit beta 3 ISO SMPDB SMP:00267 NCBI chr 9:9,179,667...9,231,061
Ensembl chr 9:9,182,562...9,231,451 		JBrowse link
warfarin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00268 NCBI chr 9:26,183,852...26,199,927
Ensembl chr 9:26,183,852...26,199,927 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00268 NCBI chr22:60,585,563...60,597,027
Ensembl chr22:60,571,822...60,597,024 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00268 NCBI chr16:44,469,609...44,492,833
Ensembl chr16:44,469,632...44,540,292 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00268 NCBI chr 4:35,950,642...35,968,137
Ensembl chr 4:35,950,695...35,998,025 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00268 NCBI chr35:6,186,750...6,347,522
Ensembl chr35:6,187,235...6,349,773 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00268 NCBI chr 7:5,674,458...5,700,928
Ensembl chr 7:5,674,416...5,700,905 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00268 NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00268 NCBI chr 6:54,709,581...54,720,603
Ensembl chr 6:54,708,471...54,720,607 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00268 NCBI chr 7:28,999,481...29,069,603
Ensembl chr 7:28,999,512...29,069,296 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00268 NCBI chr22:60,572,459...60,582,743
Ensembl chr22:60,571,822...60,597,024 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00268 NCBI chr  X:122,894,974...123,046,343
Ensembl chr  X:122,885,162...123,043,414 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00268 NCBI chr  X:109,501,341...109,533,798
Ensembl chr  X:109,501,341...109,533,798 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00268 NCBI chr15:52,238,305...52,247,017
Ensembl chr15:52,236,198...52,246,975 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00268 NCBI chr15:52,220,690...52,228,526
Ensembl chr15:52,220,611...52,228,250 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00268 NCBI chr15:52,261,215...52,270,077
Ensembl chr15:52,261,217...52,269,964 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00268 NCBI chr17:39,512,293...39,525,251
Ensembl chr17:39,512,387...39,529,121 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00268 NCBI chr16:44,492,735...44,517,854
Ensembl chr16:44,469,632...44,540,292 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00268 NCBI chr16:23,469,590...23,496,013 JBrowse link
G PLG plasminogen ISO SMPDB SMP:00268 NCBI chr 1:49,497,229...49,535,260
Ensembl chr 1:49,497,229...49,535,260 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB
RGD		 PMID:26287237 RGD:11354881 SMP:00268 NCBI chr 6:17,140,565...17,142,621
Ensembl chr 6:17,140,633...17,142,547 		JBrowse link
warfarin pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO RGD PMID:26655108 RGD:11354883 NCBI chr30:37,793,277...37,799,535
Ensembl chr30:37,793,508...37,796,866 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 ISO RGD PMID:26655108 RGD:11354883 NCBI chr30:37,818,400...37,824,192
Ensembl chr30:37,799,140...37,824,135 		JBrowse link
G CYP2C18 cytochrome P450 2C21 ISO RGD PMID:26655108 RGD:11354883 NCBI chr28:8,727,010...8,750,427
Ensembl chr28:8,727,019...8,750,587 		JBrowse link
G CYP2C41 cytochrome P450 2C41 ISO RGD PMID:26655108 RGD:11354883
G CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 ISO RGD PMID:26655108 RGD:11354883 NCBI chr 6:9,836,685...9,869,520
Ensembl chr 6:9,777,659...9,869,352 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4046
    drug pathway 379
      blood and blood forming organs drug pathway 57
        antithrombotic drug pathway 57
          anticoagulant drug pathway + 26
          antiplatelet drug pathway + 34
          other antithrombotic drug pathway + 21
          thrombolytic drug pathway + 20
paths to the root