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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:antithrombotic drug pathway
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Accession:PW:0001651 term browser browse the term
Definition:The pharmacokinetics and pharmacodynamics pathway of drugs that reduce or prevent the formation of blood clots. They are further classified depending on the blood clotting processes they affect. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: anticoagulant drug pathway

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abciximab pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itga2b integrin subunit alpha 2b ISO SMPDB SMP:00265 NCBI chrNW_004955451:17,381,323...17,392,122
Ensembl chrNW_004955451:17,382,779...17,391,859 		JBrowse link
G Itgb3 integrin subunit beta 3 ISO SMPDB SMP:00265 NCBI chrNW_004955478:9,788,192...9,830,254
Ensembl chrNW_004955478:9,788,149...9,823,746 		JBrowse link
acenocoumarol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00269 NCBI chrNW_004955451:11,468,156...11,484,410
Ensembl chrNW_004955451:11,468,290...11,483,073 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00269 NCBI chrNW_004955404:666,142...682,598
Ensembl chrNW_004955404:666,165...682,538 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00269 NCBI chrNW_004955403:22,811,211...22,830,281
Ensembl chrNW_004955403:22,811,380...22,830,563 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00269 NCBI chrNW_004955408:29,644,279...29,665,161
Ensembl chrNW_004955408:29,642,096...29,650,950 		JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00269 NCBI chrNW_004955465:7,444,118...7,617,366
Ensembl chrNW_004955465:7,443,166...7,617,436 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00269 NCBI chrNW_004955406:33,633,911...33,660,506
Ensembl chrNW_004955406:33,632,144...33,660,535 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00269 NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00269 NCBI chrNW_004955423:254,060...264,448
Ensembl chrNW_004955423:254,189...264,159 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00269 NCBI chrNW_004955462:7,695,004...7,757,832
Ensembl chrNW_004955462:7,694,939...7,757,463 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00269 NCBI chrNW_004955404:685,170...692,797
Ensembl chrNW_004955404:680,594...693,665 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00269 NCBI chrNW_004955594:658,686...800,101
Ensembl chrNW_004955594:658,523...802,865 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00269 NCBI chrNW_004955489:5,747,718...5,780,899
Ensembl chrNW_004955489:5,749,187...5,780,866 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00269 NCBI chrNW_004955471:8,806,964...8,814,671
Ensembl chrNW_004955471:8,806,650...8,816,791 		JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00269 NCBI chrNW_004955471:8,824,901...8,832,836
Ensembl chrNW_004955471:8,822,965...8,832,884 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00269 NCBI chrNW_004955471:8,786,910...8,794,947
Ensembl chrNW_004955471:8,786,910...8,795,013 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00269 NCBI chrNW_004955424:1,926,924...1,952,635
Ensembl chrNW_004955424:1,936,772...1,952,635 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00269 NCBI chrNW_004955403:22,835,544...22,856,355
Ensembl chrNW_004955403:22,833,982...22,856,389 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00269 NCBI chrNW_004955536:730,962...754,333
Ensembl chrNW_004955536:730,981...756,394 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00269 NCBI chrNW_004955439:20,317,814...20,366,724
Ensembl chrNW_004955439:20,317,552...20,366,475 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00269 NCBI chrNW_004955493:7,928,516...7,931,265 JBrowse link
acetylsalicylic acid pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12b arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00083 NCBI chrNW_004955467:8,876,186...8,887,980
Ensembl chrNW_004955467:8,876,027...8,888,033 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00083 NCBI chrNW_004955467:10,032,792...10,039,789 JBrowse link
G Alox15b arachidonate 15-lipoxygenase type B ISO SMPDB SMP:00083 NCBI chrNW_004955467:8,896,740...8,906,032
Ensembl chrNW_004955467:8,895,095...8,906,009 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00083 NCBI chrNW_004955546:2,495,226...2,550,909
Ensembl chrNW_004955546:2,494,819...2,550,909 		JBrowse link
G Cbr1 carbonyl reductase 1 ISO SMPDB SMP:00083 NCBI chrNW_004955407:35,351,601...35,354,510 JBrowse link
G Ephx2 epoxide hydrolase 2 ISO SMPDB SMP:00083 NCBI chrNW_004955403:49,999,563...50,038,800
Ensembl chrNW_004955403:49,999,563...50,041,572 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 ISO SMPDB SMP:00083 NCBI chrNW_004955455:8,082,578...8,099,523 JBrowse link
G Gpx1 glutathione peroxidase 1 ISO SMPDB SMP:00083 NCBI chrNW_004955532:1,298,336...1,298,830 JBrowse link
G LOC102026028 cytochrome P450 2E1 ISO SMPDB SMP:00083 NCBI chrNW_004955507:6,293,162...6,303,255
Ensembl chrNW_004955507:6,289,576...6,304,193 		JBrowse link
G LOC102028874 cytochrome P450 2U1 ISO SMPDB SMP:00083 NCBI chrNW_004955496:1,873,031...1,887,840
Ensembl chrNW_004955496:1,875,401...1,882,542 		JBrowse link
G Lta4h leukotriene A4 hydrolase ISO SMPDB SMP:00083 NCBI chrNW_004955405:32,345,005...32,377,685
Ensembl chrNW_004955405:32,344,925...32,378,384 		JBrowse link
G Ltc4s leukotriene C4 synthase ISO SMPDB SMP:00083 NCBI chrNW_004955408:788,856...791,505 JBrowse link
G Pla2g4b phospholipase A2 group IVB ISO SMPDB SMP:00083 NCBI chrNW_004955416:8,633,249...8,643,219
Ensembl chrNW_004955416:8,634,184...8,642,833 		JBrowse link
G Prxl2b peroxiredoxin like 2B ISO SMPDB SMP:00083 NCBI chrNW_004955486:8,663,708...8,666,369
Ensembl chrNW_004955486:8,663,595...8,666,469 		JBrowse link
G Ptgds prostaglandin D2 synthase ISO SMPDB SMP:00083 NCBI chrNW_004955513:5,009,530...5,012,781
Ensembl chrNW_004955513:5,009,625...5,012,781 		JBrowse link
G Ptges prostaglandin E synthase ISO SMPDB SMP:00083 NCBI chrNW_004955445:10,053,745...10,056,981 JBrowse link
G Ptgis prostaglandin I2 synthase ISO SMPDB SMP:00083 NCBI chrNW_004955445:8,624,228...8,663,385
Ensembl chrNW_004955445:8,623,430...8,677,658 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00083 NCBI chrNW_004955419:5,678,750...5,699,305
Ensembl chrNW_004955419:5,678,694...5,699,305 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00083 NCBI chrNW_004955406:25,077,988...25,086,259
Ensembl chrNW_004955406:25,079,945...25,086,171 		JBrowse link
G Tbxas1 thromboxane A synthase 1 ISO SMPDB SMP:00083 NCBI chrNW_004955494:3,161,032...3,321,974
Ensembl chrNW_004955494:3,160,653...3,334,411 		JBrowse link
alteplase pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00280 NCBI chrNW_004955451:11,468,156...11,484,410
Ensembl chrNW_004955451:11,468,290...11,483,073 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00280 NCBI chrNW_004955404:666,142...682,598
Ensembl chrNW_004955404:666,165...682,538 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00280 NCBI chrNW_004955403:22,811,211...22,830,281
Ensembl chrNW_004955403:22,811,380...22,830,563 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00280 NCBI chrNW_004955408:29,644,279...29,665,161
Ensembl chrNW_004955408:29,642,096...29,650,950 		JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00280 NCBI chrNW_004955465:7,444,118...7,617,366
Ensembl chrNW_004955465:7,443,166...7,617,436 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00280 NCBI chrNW_004955406:33,633,911...33,660,506
Ensembl chrNW_004955406:33,632,144...33,660,535 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00280 NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00280 NCBI chrNW_004955423:254,060...264,448
Ensembl chrNW_004955423:254,189...264,159 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00280 NCBI chrNW_004955462:7,695,004...7,757,832
Ensembl chrNW_004955462:7,694,939...7,757,463 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00280 NCBI chrNW_004955404:685,170...692,797
Ensembl chrNW_004955404:680,594...693,665 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00280 NCBI chrNW_004955594:658,686...800,101
Ensembl chrNW_004955594:658,523...802,865 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00280 NCBI chrNW_004955489:5,747,718...5,780,899
Ensembl chrNW_004955489:5,749,187...5,780,866 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00280 NCBI chrNW_004955471:8,806,964...8,814,671
Ensembl chrNW_004955471:8,806,650...8,816,791 		JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00280 NCBI chrNW_004955471:8,824,901...8,832,836
Ensembl chrNW_004955471:8,822,965...8,832,884 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00280 NCBI chrNW_004955471:8,786,910...8,794,947
Ensembl chrNW_004955471:8,786,910...8,795,013 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00280 NCBI chrNW_004955424:1,926,924...1,952,635
Ensembl chrNW_004955424:1,936,772...1,952,635 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00280 NCBI chrNW_004955403:22,835,544...22,856,355
Ensembl chrNW_004955403:22,833,982...22,856,389 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00280 NCBI chrNW_004955536:730,962...754,333
Ensembl chrNW_004955536:730,981...756,394 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00280 NCBI chrNW_004955439:20,317,814...20,366,724
Ensembl chrNW_004955439:20,317,552...20,366,475 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00280 NCBI chrNW_004955493:7,928,516...7,931,265 JBrowse link
anistreplase pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00281 NCBI chrNW_004955451:11,468,156...11,484,410
Ensembl chrNW_004955451:11,468,290...11,483,073 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00281 NCBI chrNW_004955404:666,142...682,598
Ensembl chrNW_004955404:666,165...682,538 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00281 NCBI chrNW_004955403:22,811,211...22,830,281
Ensembl chrNW_004955403:22,811,380...22,830,563 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00281 NCBI chrNW_004955408:29,644,279...29,665,161
Ensembl chrNW_004955408:29,642,096...29,650,950 		JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00281 NCBI chrNW_004955465:7,444,118...7,617,366
Ensembl chrNW_004955465:7,443,166...7,617,436 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00281 NCBI chrNW_004955406:33,633,911...33,660,506
Ensembl chrNW_004955406:33,632,144...33,660,535 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00281 NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00281 NCBI chrNW_004955423:254,060...264,448
Ensembl chrNW_004955423:254,189...264,159 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00281 NCBI chrNW_004955462:7,695,004...7,757,832
Ensembl chrNW_004955462:7,694,939...7,757,463 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00281 NCBI chrNW_004955404:685,170...692,797
Ensembl chrNW_004955404:680,594...693,665 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00281 NCBI chrNW_004955594:658,686...800,101
Ensembl chrNW_004955594:658,523...802,865 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00281 NCBI chrNW_004955489:5,747,718...5,780,899
Ensembl chrNW_004955489:5,749,187...5,780,866 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00281 NCBI chrNW_004955471:8,806,964...8,814,671
Ensembl chrNW_004955471:8,806,650...8,816,791 		JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00281 NCBI chrNW_004955471:8,824,901...8,832,836
Ensembl chrNW_004955471:8,822,965...8,832,884 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00281 NCBI chrNW_004955471:8,786,910...8,794,947
Ensembl chrNW_004955471:8,786,910...8,795,013 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00281 NCBI chrNW_004955424:1,926,924...1,952,635
Ensembl chrNW_004955424:1,936,772...1,952,635 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00281 NCBI chrNW_004955403:22,835,544...22,856,355
Ensembl chrNW_004955403:22,833,982...22,856,389 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00281 NCBI chrNW_004955536:730,962...754,333
Ensembl chrNW_004955536:730,981...756,394 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00281 NCBI chrNW_004955439:20,317,814...20,366,724
Ensembl chrNW_004955439:20,317,552...20,366,475 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00281 NCBI chrNW_004955493:7,928,516...7,931,265 JBrowse link
argatroban pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00276 NCBI chrNW_004955451:11,468,156...11,484,410
Ensembl chrNW_004955451:11,468,290...11,483,073 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00276 NCBI chrNW_004955404:666,142...682,598
Ensembl chrNW_004955404:666,165...682,538 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00276 NCBI chrNW_004955403:22,811,211...22,830,281
Ensembl chrNW_004955403:22,811,380...22,830,563 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00276 NCBI chrNW_004955408:29,644,279...29,665,161
Ensembl chrNW_004955408:29,642,096...29,650,950 		JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00276 NCBI chrNW_004955465:7,444,118...7,617,366
Ensembl chrNW_004955465:7,443,166...7,617,436 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00276 NCBI chrNW_004955406:33,633,911...33,660,506
Ensembl chrNW_004955406:33,632,144...33,660,535 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00276 NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00276 NCBI chrNW_004955423:254,060...264,448
Ensembl chrNW_004955423:254,189...264,159 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00276 NCBI chrNW_004955462:7,695,004...7,757,832
Ensembl chrNW_004955462:7,694,939...7,757,463 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00276 NCBI chrNW_004955404:685,170...692,797
Ensembl chrNW_004955404:680,594...693,665 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00276 NCBI chrNW_004955594:658,686...800,101
Ensembl chrNW_004955594:658,523...802,865 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00276 NCBI chrNW_004955489:5,747,718...5,780,899
Ensembl chrNW_004955489:5,749,187...5,780,866 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00276 NCBI chrNW_004955471:8,806,964...8,814,671
Ensembl chrNW_004955471:8,806,650...8,816,791 		JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00276 NCBI chrNW_004955471:8,824,901...8,832,836
Ensembl chrNW_004955471:8,822,965...8,832,884 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00276 NCBI chrNW_004955471:8,786,910...8,794,947
Ensembl chrNW_004955471:8,786,910...8,795,013 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00276 NCBI chrNW_004955424:1,926,924...1,952,635
Ensembl chrNW_004955424:1,936,772...1,952,635 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00276 NCBI chrNW_004955403:22,835,544...22,856,355
Ensembl chrNW_004955403:22,833,982...22,856,389 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00276 NCBI chrNW_004955536:730,962...754,333
Ensembl chrNW_004955536:730,981...756,394 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00276 NCBI chrNW_004955439:20,317,814...20,366,724
Ensembl chrNW_004955439:20,317,552...20,366,475 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00276 NCBI chrNW_004955493:7,928,516...7,931,265 JBrowse link
bivalirudin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00277 NCBI chrNW_004955451:11,468,156...11,484,410
Ensembl chrNW_004955451:11,468,290...11,483,073 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00277 NCBI chrNW_004955404:666,142...682,598
Ensembl chrNW_004955404:666,165...682,538 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00277 NCBI chrNW_004955403:22,811,211...22,830,281
Ensembl chrNW_004955403:22,811,380...22,830,563 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00277 NCBI chrNW_004955408:29,644,279...29,665,161
Ensembl chrNW_004955408:29,642,096...29,650,950 		JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00277 NCBI chrNW_004955465:7,444,118...7,617,366
Ensembl chrNW_004955465:7,443,166...7,617,436 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00277 NCBI chrNW_004955406:33,633,911...33,660,506
Ensembl chrNW_004955406:33,632,144...33,660,535 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00277 NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00277 NCBI chrNW_004955423:254,060...264,448
Ensembl chrNW_004955423:254,189...264,159 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00277 NCBI chrNW_004955462:7,695,004...7,757,832
Ensembl chrNW_004955462:7,694,939...7,757,463 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00277 NCBI chrNW_004955404:685,170...692,797
Ensembl chrNW_004955404:680,594...693,665 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00277 NCBI chrNW_004955594:658,686...800,101
Ensembl chrNW_004955594:658,523...802,865 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00277 NCBI chrNW_004955489:5,747,718...5,780,899
Ensembl chrNW_004955489:5,749,187...5,780,866 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00277 NCBI chrNW_004955471:8,806,964...8,814,671
Ensembl chrNW_004955471:8,806,650...8,816,791 		JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00277 NCBI chrNW_004955471:8,824,901...8,832,836
Ensembl chrNW_004955471:8,822,965...8,832,884 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00277 NCBI chrNW_004955471:8,786,910...8,794,947
Ensembl chrNW_004955471:8,786,910...8,795,013 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00277 NCBI chrNW_004955424:1,926,924...1,952,635
Ensembl chrNW_004955424:1,936,772...1,952,635 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00277 NCBI chrNW_004955403:22,835,544...22,856,355
Ensembl chrNW_004955403:22,833,982...22,856,389 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00277 NCBI chrNW_004955536:730,962...754,333
Ensembl chrNW_004955536:730,981...756,394 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00277 NCBI chrNW_004955439:20,317,814...20,366,724
Ensembl chrNW_004955439:20,317,552...20,366,475 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00277 NCBI chrNW_004955493:7,928,516...7,931,265 JBrowse link
cilostazol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde4d phosphodiesterase 4D ISO SMPDB SMP:00263 NCBI chrNW_004955446:7,914,326...9,252,527
Ensembl chrNW_004955446:8,211,877...9,252,653 		JBrowse link
clopidogrel pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1 ATP binding cassette subfamily B member 1 ISO SMPDB SMP:00260 NCBI chrNW_004955432:4,911,774...5,085,349 JBrowse link
G LOC102010322 cytochrome P450 1A2 ISO SMPDB SMP:00260 NCBI chrNW_004955450:3,165,107...3,171,894
Ensembl chrNW_004955450:3,165,106...3,171,942 		JBrowse link
G P2ry12 purinergic receptor P2Y12 ISO SMPDB SMP:00260 NCBI chrNW_004955448:2,442,368...2,488,567
Ensembl chrNW_004955448:2,442,368...2,488,567 		JBrowse link
G Pon1 paraoxonase 1 ISO SMPDB SMP:00260 NCBI chrNW_004955432:11,893,473...11,923,035
Ensembl chrNW_004955432:11,893,473...11,923,339 		JBrowse link
clopidogrel pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1 ATP binding cassette subfamily B member 1 ISO SMPDB SMP:00610 NCBI chrNW_004955432:4,911,774...5,085,349 JBrowse link
G LOC102010322 cytochrome P450 1A2 ISO SMPDB SMP:00610 NCBI chrNW_004955450:3,165,107...3,171,894
Ensembl chrNW_004955450:3,165,106...3,171,942 		JBrowse link
G P2ry12 purinergic receptor P2Y12 ISO SMPDB SMP:00610 NCBI chrNW_004955448:2,442,368...2,488,567
Ensembl chrNW_004955448:2,442,368...2,488,567 		JBrowse link
G Pon1 paraoxonase 1 ISO SMPDB SMP:00610 NCBI chrNW_004955432:11,893,473...11,923,035
Ensembl chrNW_004955432:11,893,473...11,923,339 		JBrowse link
dicoumarol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955451:11,468,156...11,484,410
Ensembl chrNW_004955451:11,468,290...11,483,073 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955404:666,142...682,598
Ensembl chrNW_004955404:666,165...682,538 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955403:22,811,211...22,830,281
Ensembl chrNW_004955403:22,811,380...22,830,563 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955408:29,644,279...29,665,161
Ensembl chrNW_004955408:29,642,096...29,650,950 		JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955465:7,444,118...7,617,366
Ensembl chrNW_004955465:7,443,166...7,617,436 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955406:33,633,911...33,660,506
Ensembl chrNW_004955406:33,632,144...33,660,535 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955423:254,060...264,448
Ensembl chrNW_004955423:254,189...264,159 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955462:7,695,004...7,757,832
Ensembl chrNW_004955462:7,694,939...7,757,463 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955404:685,170...692,797
Ensembl chrNW_004955404:680,594...693,665 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955594:658,686...800,101
Ensembl chrNW_004955594:658,523...802,865 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955489:5,747,718...5,780,899
Ensembl chrNW_004955489:5,749,187...5,780,866 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955471:8,806,964...8,814,671
Ensembl chrNW_004955471:8,806,650...8,816,791 		JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955471:8,824,901...8,832,836
Ensembl chrNW_004955471:8,822,965...8,832,884 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955471:8,786,910...8,794,947
Ensembl chrNW_004955471:8,786,910...8,795,013 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955424:1,926,924...1,952,635
Ensembl chrNW_004955424:1,936,772...1,952,635 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955403:22,835,544...22,856,355
Ensembl chrNW_004955403:22,833,982...22,856,389 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955536:730,962...754,333
Ensembl chrNW_004955536:730,981...756,394 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955439:20,317,814...20,366,724
Ensembl chrNW_004955439:20,317,552...20,366,475 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00270 SMP:00656 NCBI chrNW_004955493:7,928,516...7,931,265 JBrowse link
dipyridamole pharmacodyamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde4d phosphodiesterase 4D ISO SMPDB SMP:00264 NCBI chrNW_004955446:7,914,326...9,252,527
Ensembl chrNW_004955446:8,211,877...9,252,653 		JBrowse link
enoxaparin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00272 NCBI chrNW_004955451:11,468,156...11,484,410
Ensembl chrNW_004955451:11,468,290...11,483,073 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00272 NCBI chrNW_004955404:666,142...682,598
Ensembl chrNW_004955404:666,165...682,538 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00272 NCBI chrNW_004955403:22,811,211...22,830,281
Ensembl chrNW_004955403:22,811,380...22,830,563 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00272 NCBI chrNW_004955408:29,644,279...29,665,161
Ensembl chrNW_004955408:29,642,096...29,650,950 		JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00272 NCBI chrNW_004955465:7,444,118...7,617,366
Ensembl chrNW_004955465:7,443,166...7,617,436 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00272 NCBI chrNW_004955406:33,633,911...33,660,506
Ensembl chrNW_004955406:33,632,144...33,660,535 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00272 NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00272 NCBI chrNW_004955423:254,060...264,448
Ensembl chrNW_004955423:254,189...264,159 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00272 NCBI chrNW_004955462:7,695,004...7,757,832
Ensembl chrNW_004955462:7,694,939...7,757,463 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00272 NCBI chrNW_004955404:685,170...692,797
Ensembl chrNW_004955404:680,594...693,665 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00272 NCBI chrNW_004955594:658,686...800,101
Ensembl chrNW_004955594:658,523...802,865 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00272 NCBI chrNW_004955489:5,747,718...5,780,899
Ensembl chrNW_004955489:5,749,187...5,780,866 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00272 NCBI chrNW_004955471:8,806,964...8,814,671
Ensembl chrNW_004955471:8,806,650...8,816,791 		JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00272 NCBI chrNW_004955471:8,824,901...8,832,836
Ensembl chrNW_004955471:8,822,965...8,832,884 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00272 NCBI chrNW_004955471:8,786,910...8,794,947
Ensembl chrNW_004955471:8,786,910...8,795,013 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00272 NCBI chrNW_004955424:1,926,924...1,952,635
Ensembl chrNW_004955424:1,936,772...1,952,635 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00272 NCBI chrNW_004955403:22,835,544...22,856,355
Ensembl chrNW_004955403:22,833,982...22,856,389 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00272 NCBI chrNW_004955536:730,962...754,333
Ensembl chrNW_004955536:730,981...756,394 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00272 NCBI chrNW_004955439:20,317,814...20,366,724
Ensembl chrNW_004955439:20,317,552...20,366,475 		JBrowse link
G Serpinc1 serpin family C member 1 ISO SMPDB SMP:00272 NCBI chrNW_004955406:14,024,183...14,036,206
Ensembl chrNW_004955406:14,024,313...14,035,948 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00272 NCBI chrNW_004955493:7,928,516...7,931,265 JBrowse link
eptifibatide pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itga2b integrin subunit alpha 2b ISO SMPDB SMP:00266 NCBI chrNW_004955451:17,381,323...17,392,122
Ensembl chrNW_004955451:17,382,779...17,391,859 		JBrowse link
G Itgb3 integrin subunit beta 3 ISO SMPDB SMP:00266 NCBI chrNW_004955478:9,788,192...9,830,254
Ensembl chrNW_004955478:9,788,149...9,823,746 		JBrowse link
fondaparinux pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00273 NCBI chrNW_004955451:11,468,156...11,484,410
Ensembl chrNW_004955451:11,468,290...11,483,073 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00273 NCBI chrNW_004955404:666,142...682,598
Ensembl chrNW_004955404:666,165...682,538 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00273 NCBI chrNW_004955403:22,811,211...22,830,281
Ensembl chrNW_004955403:22,811,380...22,830,563 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00273 NCBI chrNW_004955408:29,644,279...29,665,161
Ensembl chrNW_004955408:29,642,096...29,650,950 		JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00273 NCBI chrNW_004955465:7,444,118...7,617,366
Ensembl chrNW_004955465:7,443,166...7,617,436 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00273 NCBI chrNW_004955406:33,633,911...33,660,506
Ensembl chrNW_004955406:33,632,144...33,660,535 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00273 NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00273 NCBI chrNW_004955423:254,060...264,448
Ensembl chrNW_004955423:254,189...264,159 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00273 NCBI chrNW_004955462:7,695,004...7,757,832
Ensembl chrNW_004955462:7,694,939...7,757,463 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00273 NCBI chrNW_004955404:685,170...692,797
Ensembl chrNW_004955404:680,594...693,665 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00273 NCBI chrNW_004955594:658,686...800,101
Ensembl chrNW_004955594:658,523...802,865 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00273 NCBI chrNW_004955489:5,747,718...5,780,899
Ensembl chrNW_004955489:5,749,187...5,780,866 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00273 NCBI chrNW_004955471:8,806,964...8,814,671
Ensembl chrNW_004955471:8,806,650...8,816,791 		JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00273 NCBI chrNW_004955471:8,824,901...8,832,836
Ensembl chrNW_004955471:8,822,965...8,832,884 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00273 NCBI chrNW_004955471:8,786,910...8,794,947
Ensembl chrNW_004955471:8,786,910...8,795,013 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00273 NCBI chrNW_004955424:1,926,924...1,952,635
Ensembl chrNW_004955424:1,936,772...1,952,635 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00273 NCBI chrNW_004955403:22,835,544...22,856,355
Ensembl chrNW_004955403:22,833,982...22,856,389 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00273 NCBI chrNW_004955536:730,962...754,333
Ensembl chrNW_004955536:730,981...756,394 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00273 NCBI chrNW_004955439:20,317,814...20,366,724
Ensembl chrNW_004955439:20,317,552...20,366,475 		JBrowse link
G Serpinc1 serpin family C member 1 ISO SMPDB SMP:00273 NCBI chrNW_004955406:14,024,183...14,036,206
Ensembl chrNW_004955406:14,024,313...14,035,948 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00273 NCBI chrNW_004955493:7,928,516...7,931,265 JBrowse link
heparin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00274 NCBI chrNW_004955451:11,468,156...11,484,410
Ensembl chrNW_004955451:11,468,290...11,483,073 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00274 NCBI chrNW_004955404:666,142...682,598
Ensembl chrNW_004955404:666,165...682,538 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00274 NCBI chrNW_004955403:22,811,211...22,830,281
Ensembl chrNW_004955403:22,811,380...22,830,563 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00274 NCBI chrNW_004955408:29,644,279...29,665,161
Ensembl chrNW_004955408:29,642,096...29,650,950 		JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00274 NCBI chrNW_004955465:7,444,118...7,617,366
Ensembl chrNW_004955465:7,443,166...7,617,436 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00274 NCBI chrNW_004955406:33,633,911...33,660,506
Ensembl chrNW_004955406:33,632,144...33,660,535 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00274 NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00274 NCBI chrNW_004955423:254,060...264,448
Ensembl chrNW_004955423:254,189...264,159 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00274 NCBI chrNW_004955462:7,695,004...7,757,832
Ensembl chrNW_004955462:7,694,939...7,757,463 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00274 NCBI chrNW_004955404:685,170...692,797
Ensembl chrNW_004955404:680,594...693,665 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00274 NCBI chrNW_004955594:658,686...800,101
Ensembl chrNW_004955594:658,523...802,865 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00274 NCBI chrNW_004955489:5,747,718...5,780,899
Ensembl chrNW_004955489:5,749,187...5,780,866 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00274 NCBI chrNW_004955471:8,806,964...8,814,671
Ensembl chrNW_004955471:8,806,650...8,816,791 		JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00274 NCBI chrNW_004955471:8,824,901...8,832,836
Ensembl chrNW_004955471:8,822,965...8,832,884 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00274 NCBI chrNW_004955471:8,786,910...8,794,947
Ensembl chrNW_004955471:8,786,910...8,795,013 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00274 NCBI chrNW_004955424:1,926,924...1,952,635
Ensembl chrNW_004955424:1,936,772...1,952,635 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00274 NCBI chrNW_004955403:22,835,544...22,856,355
Ensembl chrNW_004955403:22,833,982...22,856,389 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00274 NCBI chrNW_004955536:730,962...754,333
Ensembl chrNW_004955536:730,981...756,394 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00274 NCBI chrNW_004955439:20,317,814...20,366,724
Ensembl chrNW_004955439:20,317,552...20,366,475 		JBrowse link
G Serpinc1 serpin family C member 1 ISO SMPDB SMP:00274 NCBI chrNW_004955406:14,024,183...14,036,206
Ensembl chrNW_004955406:14,024,313...14,035,948 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00274 NCBI chrNW_004955493:7,928,516...7,931,265 JBrowse link
phenindione pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00655 NCBI chrNW_004955451:11,468,156...11,484,410
Ensembl chrNW_004955451:11,468,290...11,483,073 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00655 NCBI chrNW_004955404:666,142...682,598
Ensembl chrNW_004955404:666,165...682,538 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00655 NCBI chrNW_004955403:22,811,211...22,830,281
Ensembl chrNW_004955403:22,811,380...22,830,563 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00655 NCBI chrNW_004955408:29,644,279...29,665,161
Ensembl chrNW_004955408:29,642,096...29,650,950 		JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00655 NCBI chrNW_004955465:7,444,118...7,617,366
Ensembl chrNW_004955465:7,443,166...7,617,436 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00655 NCBI chrNW_004955406:33,633,911...33,660,506
Ensembl chrNW_004955406:33,632,144...33,660,535 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00655 NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00655 NCBI chrNW_004955423:254,060...264,448
Ensembl chrNW_004955423:254,189...264,159 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00655 NCBI chrNW_004955462:7,695,004...7,757,832
Ensembl chrNW_004955462:7,694,939...7,757,463 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00655 NCBI chrNW_004955404:685,170...692,797
Ensembl chrNW_004955404:680,594...693,665 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00655 NCBI chrNW_004955594:658,686...800,101
Ensembl chrNW_004955594:658,523...802,865 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00655 NCBI chrNW_004955489:5,747,718...5,780,899
Ensembl chrNW_004955489:5,749,187...5,780,866 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00655 NCBI chrNW_004955471:8,806,964...8,814,671
Ensembl chrNW_004955471:8,806,650...8,816,791 		JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00655 NCBI chrNW_004955471:8,824,901...8,832,836
Ensembl chrNW_004955471:8,822,965...8,832,884 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00655 NCBI chrNW_004955471:8,786,910...8,794,947
Ensembl chrNW_004955471:8,786,910...8,795,013 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00655 NCBI chrNW_004955424:1,926,924...1,952,635
Ensembl chrNW_004955424:1,936,772...1,952,635 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00655 NCBI chrNW_004955403:22,835,544...22,856,355
Ensembl chrNW_004955403:22,833,982...22,856,389 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00655 NCBI chrNW_004955536:730,962...754,333
Ensembl chrNW_004955536:730,981...756,394 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00655 NCBI chrNW_004955439:20,317,814...20,366,724
Ensembl chrNW_004955439:20,317,552...20,366,475 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00655 NCBI chrNW_004955493:7,928,516...7,931,265 JBrowse link
reteplase pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00285 NCBI chrNW_004955451:11,468,156...11,484,410
Ensembl chrNW_004955451:11,468,290...11,483,073 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00285 NCBI chrNW_004955404:666,142...682,598
Ensembl chrNW_004955404:666,165...682,538 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00285 NCBI chrNW_004955403:22,811,211...22,830,281
Ensembl chrNW_004955403:22,811,380...22,830,563 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00285 NCBI chrNW_004955408:29,644,279...29,665,161
Ensembl chrNW_004955408:29,642,096...29,650,950 		JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00285 NCBI chrNW_004955465:7,444,118...7,617,366
Ensembl chrNW_004955465:7,443,166...7,617,436 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00285 NCBI chrNW_004955406:33,633,911...33,660,506
Ensembl chrNW_004955406:33,632,144...33,660,535 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00285 NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00285 NCBI chrNW_004955423:254,060...264,448
Ensembl chrNW_004955423:254,189...264,159 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00285 NCBI chrNW_004955462:7,695,004...7,757,832
Ensembl chrNW_004955462:7,694,939...7,757,463 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00285 NCBI chrNW_004955404:685,170...692,797
Ensembl chrNW_004955404:680,594...693,665 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00285 NCBI chrNW_004955594:658,686...800,101
Ensembl chrNW_004955594:658,523...802,865 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00285 NCBI chrNW_004955489:5,747,718...5,780,899
Ensembl chrNW_004955489:5,749,187...5,780,866 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00285 NCBI chrNW_004955471:8,806,964...8,814,671
Ensembl chrNW_004955471:8,806,650...8,816,791 		JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00285 NCBI chrNW_004955471:8,824,901...8,832,836
Ensembl chrNW_004955471:8,822,965...8,832,884 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00285 NCBI chrNW_004955471:8,786,910...8,794,947
Ensembl chrNW_004955471:8,786,910...8,795,013 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00285 NCBI chrNW_004955424:1,926,924...1,952,635
Ensembl chrNW_004955424:1,936,772...1,952,635 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00285 NCBI chrNW_004955403:22,835,544...22,856,355
Ensembl chrNW_004955403:22,833,982...22,856,389 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00285 NCBI chrNW_004955536:730,962...754,333
Ensembl chrNW_004955536:730,981...756,394 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00285 NCBI chrNW_004955439:20,317,814...20,366,724
Ensembl chrNW_004955439:20,317,552...20,366,475 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00285 NCBI chrNW_004955493:7,928,516...7,931,265 JBrowse link
salicylic acid pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12b arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00709 NCBI chrNW_004955467:8,876,186...8,887,980
Ensembl chrNW_004955467:8,876,027...8,888,033 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00709 NCBI chrNW_004955467:10,032,792...10,039,789 JBrowse link
G Alox15b arachidonate 15-lipoxygenase type B ISO SMPDB SMP:00709 NCBI chrNW_004955467:8,896,740...8,906,032
Ensembl chrNW_004955467:8,895,095...8,906,009 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00709 NCBI chrNW_004955546:2,495,226...2,550,909
Ensembl chrNW_004955546:2,494,819...2,550,909 		JBrowse link
G Cbr1 carbonyl reductase 1 ISO SMPDB SMP:00709 NCBI chrNW_004955407:35,351,601...35,354,510 JBrowse link
G Ephx2 epoxide hydrolase 2 ISO SMPDB SMP:00709 NCBI chrNW_004955403:49,999,563...50,038,800
Ensembl chrNW_004955403:49,999,563...50,041,572 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 ISO SMPDB SMP:00709 NCBI chrNW_004955455:8,082,578...8,099,523 JBrowse link
G Gpx1 glutathione peroxidase 1 ISO SMPDB SMP:00709 NCBI chrNW_004955532:1,298,336...1,298,830 JBrowse link
G LOC102026028 cytochrome P450 2E1 ISO SMPDB SMP:00709 NCBI chrNW_004955507:6,293,162...6,303,255
Ensembl chrNW_004955507:6,289,576...6,304,193 		JBrowse link
G LOC102028874 cytochrome P450 2U1 ISO SMPDB SMP:00709 NCBI chrNW_004955496:1,873,031...1,887,840
Ensembl chrNW_004955496:1,875,401...1,882,542 		JBrowse link
G Lta4h leukotriene A4 hydrolase ISO SMPDB SMP:00709 NCBI chrNW_004955405:32,345,005...32,377,685
Ensembl chrNW_004955405:32,344,925...32,378,384 		JBrowse link
G Ltc4s leukotriene C4 synthase ISO SMPDB SMP:00709 NCBI chrNW_004955408:788,856...791,505 JBrowse link
G Pla2g4b phospholipase A2 group IVB ISO SMPDB SMP:00709 NCBI chrNW_004955416:8,633,249...8,643,219
Ensembl chrNW_004955416:8,634,184...8,642,833 		JBrowse link
G Prxl2b peroxiredoxin like 2B ISO SMPDB SMP:00709 NCBI chrNW_004955486:8,663,708...8,666,369
Ensembl chrNW_004955486:8,663,595...8,666,469 		JBrowse link
G Ptgds prostaglandin D2 synthase ISO SMPDB SMP:00709 NCBI chrNW_004955513:5,009,530...5,012,781
Ensembl chrNW_004955513:5,009,625...5,012,781 		JBrowse link
G Ptges prostaglandin E synthase ISO SMPDB SMP:00709 NCBI chrNW_004955445:10,053,745...10,056,981 JBrowse link
G Ptgis prostaglandin I2 synthase ISO SMPDB SMP:00709 NCBI chrNW_004955445:8,624,228...8,663,385
Ensembl chrNW_004955445:8,623,430...8,677,658 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00709 NCBI chrNW_004955419:5,678,750...5,699,305
Ensembl chrNW_004955419:5,678,694...5,699,305 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00709 NCBI chrNW_004955406:25,077,988...25,086,259
Ensembl chrNW_004955406:25,079,945...25,086,171 		JBrowse link
G Tbxas1 thromboxane A synthase 1 ISO SMPDB SMP:00709 NCBI chrNW_004955494:3,161,032...3,321,974
Ensembl chrNW_004955494:3,160,653...3,334,411 		JBrowse link
ticlopidine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2ry12 purinergic receptor P2Y12 ISO SMPDB SMP:00261 NCBI chrNW_004955448:2,442,368...2,488,567
Ensembl chrNW_004955448:2,442,368...2,488,567 		JBrowse link
ticlopidine pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2ry12 purinergic receptor P2Y12 ISO SMPDB SMP:00611 NCBI chrNW_004955448:2,442,368...2,488,567
Ensembl chrNW_004955448:2,442,368...2,488,567 		JBrowse link
tirofiban pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itga2b integrin subunit alpha 2b ISO SMPDB SMP:00267 NCBI chrNW_004955451:17,381,323...17,392,122
Ensembl chrNW_004955451:17,382,779...17,391,859 		JBrowse link
G Itgb3 integrin subunit beta 3 ISO SMPDB SMP:00267 NCBI chrNW_004955478:9,788,192...9,830,254
Ensembl chrNW_004955478:9,788,149...9,823,746 		JBrowse link
warfarin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00268 NCBI chrNW_004955451:11,468,156...11,484,410
Ensembl chrNW_004955451:11,468,290...11,483,073 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00268 NCBI chrNW_004955404:666,142...682,598
Ensembl chrNW_004955404:666,165...682,538 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00268 NCBI chrNW_004955403:22,811,211...22,830,281
Ensembl chrNW_004955403:22,811,380...22,830,563 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00268 NCBI chrNW_004955408:29,644,279...29,665,161
Ensembl chrNW_004955408:29,642,096...29,650,950 		JBrowse link
G F13a1 coagulation factor XIII A chain ISO SMPDB SMP:00268 NCBI chrNW_004955465:7,444,118...7,617,366
Ensembl chrNW_004955465:7,443,166...7,617,436 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00268 NCBI chrNW_004955406:33,633,911...33,660,506
Ensembl chrNW_004955406:33,632,144...33,660,535 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00268 NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00268 NCBI chrNW_004955423:254,060...264,448
Ensembl chrNW_004955423:254,189...264,159 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00268 NCBI chrNW_004955462:7,695,004...7,757,832
Ensembl chrNW_004955462:7,694,939...7,757,463 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00268 NCBI chrNW_004955404:685,170...692,797
Ensembl chrNW_004955404:680,594...693,665 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00268 NCBI chrNW_004955594:658,686...800,101
Ensembl chrNW_004955594:658,523...802,865 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00268 NCBI chrNW_004955489:5,747,718...5,780,899
Ensembl chrNW_004955489:5,749,187...5,780,866 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00268 NCBI chrNW_004955471:8,806,964...8,814,671
Ensembl chrNW_004955471:8,806,650...8,816,791 		JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00268 NCBI chrNW_004955471:8,824,901...8,832,836
Ensembl chrNW_004955471:8,822,965...8,832,884 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00268 NCBI chrNW_004955471:8,786,910...8,794,947
Ensembl chrNW_004955471:8,786,910...8,795,013 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00268 NCBI chrNW_004955424:1,926,924...1,952,635
Ensembl chrNW_004955424:1,936,772...1,952,635 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00268 NCBI chrNW_004955403:22,835,544...22,856,355
Ensembl chrNW_004955403:22,833,982...22,856,389 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00268 NCBI chrNW_004955536:730,962...754,333
Ensembl chrNW_004955536:730,981...756,394 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00268 NCBI chrNW_004955439:20,317,814...20,366,724
Ensembl chrNW_004955439:20,317,552...20,366,475 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB
RGD		 PMID:26287237 RGD:11354881 SMP:00268 NCBI chrNW_004955493:7,928,516...7,931,265 JBrowse link
warfarin pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC102010322 cytochrome P450 1A2 ISO RGD PMID:26655108 RGD:11354883 NCBI chrNW_004955450:3,165,107...3,171,894
Ensembl chrNW_004955450:3,165,106...3,171,942 		JBrowse link
G LOC102010850 cytochrome P450 1A1 ISO RGD PMID:26655108 RGD:11354883 NCBI chrNW_004955450:3,183,958...3,189,488
Ensembl chrNW_004955450:3,183,750...3,189,488 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 3924
    drug pathway 348
      blood and blood forming organs drug pathway 49
        antithrombotic drug pathway 49
          anticoagulant drug pathway + 23
          antiplatelet drug pathway + 27
          other antithrombotic drug pathway + 21
          thrombolytic drug pathway + 20
paths to the root