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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:antithrombotic drug pathway
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Accession:PW:0001651 term browser browse the term
Definition:The pharmacokinetics and pharmacodynamics pathway of drugs that reduce or prevent the formation of blood clots. They are further classified depending on the blood clotting processes they affect. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: anticoagulant drug pathway


show annotations for term's descendants           Sort by:
abciximab pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGA2B integrin subunit alpha 2b ISO SMPDB SMP:00265 NCBI chr17:13,009,514...13,027,289
Ensembl chr17:13,176,843...13,193,269 		JBrowse link
G ITGB3 integrin subunit beta 3 ISO SMPDB SMP:00265 NCBI chr17:10,134,450...10,194,596
Ensembl chr17:10,353,111...10,392,382 		JBrowse link
acenocoumarol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00269 NCBI chr17:44,274,349...44,291,764
Ensembl chr17:49,150,677...49,166,677 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00269 NCBI chr13:94,263,202...94,289,612
Ensembl chr13:113,332,124...113,358,660 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00269 NCBI chr 4:178,436,865...178,459,568
Ensembl chr 4:190,643,733...190,666,512 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00269 NCBI chr 5:172,703,724...172,711,618
Ensembl chr 5:179,766,243...179,773,485 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00269 NCBI chr 6:5,978,505...6,156,705
Ensembl chr 6:6,157,926...6,513,961 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00269 NCBI chr 1:172,623,336...172,651,945
Ensembl chr 1:176,937,158...176,965,773 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00269 NCBI chr11:46,669,925...46,690,391
Ensembl chr11:47,227,891...47,249,157 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00269 NCBI chr 1:97,190,381...97,203,076
Ensembl chr 1:95,918,502...95,931,050 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00269 NCBI chr 1:144,996,757...145,070,046
Ensembl chr 1:148,718,897...148,790,915 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00269 NCBI chr13:94,246,694...94,261,133
Ensembl chr13:113,315,868...113,329,995 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00269 NCBI chr  X:144,316,192...144,505,773
Ensembl chr  X:154,156,873...154,341,317 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00269 NCBI chr  X:128,684,709...128,719,020
Ensembl chr  X:138,934,167...138,967,087 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00269 NCBI chr 4:146,949,680...146,957,291 JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00269 NCBI chr 4:146,929,561...146,937,665
Ensembl chr 4:158,747,659...158,755,766 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00269 NCBI chr 4:146,970,671...146,979,348
Ensembl chr 4:158,788,966...158,797,237 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00269 NCBI chr2A:85,599,227...85,612,274
Ensembl chr2A:87,152,111...87,164,567 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00269 NCBI chr 4:178,398,359...178,429,448
Ensembl chr 4:190,604,901...190,636,300 		JBrowse link
G LOC100982214 plasminogen ISO SMPDB SMP:00269 NCBI chr 6:158,662,192...158,713,413
Ensembl chr 6:163,673,464...163,736,777 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00269 NCBI chr 8:41,419,415...41,451,951
Ensembl chr 8:38,864,918...38,897,779 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00269 NCBI chr16:23,871,756...23,876,599
Ensembl chr16:31,459,560...31,464,897 		JBrowse link
acetylsalicylic acid pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C3 aldo-keto reductase family 1 member C3 ISO SMPDB SMP:00083 NCBI chr10:5,079,580...5,157,572
Ensembl chr10:5,081,214...5,139,812 		JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO SMPDB SMP:00083 NCBI chr17:7,026,839...7,041,598
Ensembl chr17:7,014,591...7,029,602 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00083 NCBI chr17:43,569,858...43,588,039
Ensembl chr17:48,302,450...48,317,029 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00083 NCBI chr17:4,686,339...4,696,877
Ensembl chr17:4,677,125...4,687,669 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00083 NCBI chr10:42,461,398...42,531,576
Ensembl chr10:45,639,946...45,710,016 		JBrowse link
G CBR1 carbonyl reductase 1 ISO SMPDB SMP:00083 NCBI chr21:22,440,726...22,443,950
Ensembl chr21:35,800,177...35,803,458 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 ISO SMPDB SMP:00083 NCBI chr19:38,003,083...38,028,980
Ensembl chr19:46,509,370...46,534,672 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 ISO SMPDB SMP:00083 NCBI chr10:91,646,387...91,679,998
Ensembl chr10:95,157,661...95,186,620 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO SMPDB SMP:00083 Ensembl chr10:134,839,025...134,852,719 JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 ISO SMPDB SMP:00083 NCBI chr 1:59,151,079...59,184,625
Ensembl chr 1:60,856,269...60,889,810 		JBrowse link
G CYP2U1 cytochrome P450 family 2 subfamily U member 1 ISO SMPDB SMP:00083 NCBI chr 4:100,436,365...100,458,845
Ensembl chr 4:111,009,198...111,031,269 		JBrowse link
G CYP4A11 cytochrome P450 family 4 subfamily A member 11 ISO SMPDB SMP:00083 NCBI chr 1:46,228,434...46,240,736
Ensembl chr 1:47,583,564...47,594,870 		JBrowse link
G CYP4F3 cytochrome P450 family 4 subfamily F member 3 ISO SMPDB SMP:00083 NCBI chr19:15,162,886...15,182,334
Ensembl chr19:16,146,664...16,165,869 		JBrowse link
G CYP4F8 cytochrome P450 family 4 subfamily F member 8 ISO SMPDB SMP:00083 NCBI chr19:15,134,029...15,150,378
Ensembl chr19:16,118,830...16,133,182 		JBrowse link
G EPHX2 epoxide hydrolase 2 ISO SMPDB SMP:00083 NCBI chr 8:26,761,090...26,818,436
Ensembl chr 8:23,964,094...24,017,749 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO SMPDB SMP:00083 NCBI chr22:5,424,334...5,469,705 JBrowse link
G GPX1 glutathione peroxidase 1 ISO SMPDB SMP:00083 NCBI chr 3:49,280,038...49,281,455
Ensembl chr 3:50,360,947...50,361,826 		JBrowse link
G LOC100971127 arachidonate 15-lipoxygenase type B ISO SMPDB SMP:00083 NCBI chr17:43,609,146...43,619,713
Ensembl chr17:48,340,777...48,350,808 		JBrowse link
G LTA4H leukotriene A4 hydrolase ISO SMPDB SMP:00083 NCBI chr12:93,589,758...93,624,529
Ensembl chr12:96,978,203...97,012,427 		JBrowse link
G LTC4S leukotriene C4 synthase ISO SMPDB SMP:00083 NCBI chr 5:174,946,346...174,950,805 JBrowse link
G PRXL2B peroxiredoxin like 2B ISO SMPDB SMP:00083 NCBI chr 1:1,319,718...1,324,409 JBrowse link
G PTGDS prostaglandin D2 synthase ISO SMPDB SMP:00083 NCBI chr 9:108,037,994...108,042,136
Ensembl chr 9:137,006,601...137,009,680 		JBrowse link
G PTGES prostaglandin E synthase ISO SMPDB SMP:00083 NCBI chr 9:100,865,702...100,880,408
Ensembl chr 9:129,522,547...129,537,020 		JBrowse link
G PTGIS prostaglandin I2 synthase ISO SMPDB SMP:00083 NCBI chr20:45,841,238...45,905,641
Ensembl chr20:46,905,665...46,971,612 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00083 NCBI chr 9:93,495,365...93,517,557
Ensembl chr 9:121,837,095...121,859,283 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00083 NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519 		JBrowse link
G TBXAS1 thromboxane A synthase 1 ISO SMPDB SMP:00083 NCBI chr 7:131,772,947...131,958,647
Ensembl chr 7:144,255,211...144,439,523 		JBrowse link
alteplase pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00280 NCBI chr17:44,274,349...44,291,764
Ensembl chr17:49,150,677...49,166,677 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00280 NCBI chr13:94,263,202...94,289,612
Ensembl chr13:113,332,124...113,358,660 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00280 NCBI chr 4:178,436,865...178,459,568
Ensembl chr 4:190,643,733...190,666,512 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00280 NCBI chr 5:172,703,724...172,711,618
Ensembl chr 5:179,766,243...179,773,485 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00280 NCBI chr 6:5,978,505...6,156,705
Ensembl chr 6:6,157,926...6,513,961 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00280 NCBI chr 1:172,623,336...172,651,945
Ensembl chr 1:176,937,158...176,965,773 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00280 NCBI chr11:46,669,925...46,690,391
Ensembl chr11:47,227,891...47,249,157 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00280 NCBI chr 1:97,190,381...97,203,076
Ensembl chr 1:95,918,502...95,931,050 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00280 NCBI chr 1:144,996,757...145,070,046
Ensembl chr 1:148,718,897...148,790,915 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00280 NCBI chr13:94,246,694...94,261,133
Ensembl chr13:113,315,868...113,329,995 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00280 NCBI chr  X:144,316,192...144,505,773
Ensembl chr  X:154,156,873...154,341,317 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00280 NCBI chr  X:128,684,709...128,719,020
Ensembl chr  X:138,934,167...138,967,087 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00280 NCBI chr 4:146,949,680...146,957,291 JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00280 NCBI chr 4:146,929,561...146,937,665
Ensembl chr 4:158,747,659...158,755,766 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00280 NCBI chr 4:146,970,671...146,979,348
Ensembl chr 4:158,788,966...158,797,237 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00280 NCBI chr2A:85,599,227...85,612,274
Ensembl chr2A:87,152,111...87,164,567 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00280 NCBI chr 4:178,398,359...178,429,448
Ensembl chr 4:190,604,901...190,636,300 		JBrowse link
G LOC100982214 plasminogen ISO SMPDB SMP:00280 NCBI chr 6:158,662,192...158,713,413
Ensembl chr 6:163,673,464...163,736,777 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00280 NCBI chr 8:41,419,415...41,451,951
Ensembl chr 8:38,864,918...38,897,779 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00280 NCBI chr16:23,871,756...23,876,599
Ensembl chr16:31,459,560...31,464,897 		JBrowse link
anistreplase pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00281 NCBI chr17:44,274,349...44,291,764
Ensembl chr17:49,150,677...49,166,677 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00281 NCBI chr13:94,263,202...94,289,612
Ensembl chr13:113,332,124...113,358,660 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00281 NCBI chr 4:178,436,865...178,459,568
Ensembl chr 4:190,643,733...190,666,512 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00281 NCBI chr 5:172,703,724...172,711,618
Ensembl chr 5:179,766,243...179,773,485 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00281 NCBI chr 6:5,978,505...6,156,705
Ensembl chr 6:6,157,926...6,513,961 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00281 NCBI chr 1:172,623,336...172,651,945
Ensembl chr 1:176,937,158...176,965,773 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00281 NCBI chr11:46,669,925...46,690,391
Ensembl chr11:47,227,891...47,249,157 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00281 NCBI chr 1:97,190,381...97,203,076
Ensembl chr 1:95,918,502...95,931,050 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00281 NCBI chr 1:144,996,757...145,070,046
Ensembl chr 1:148,718,897...148,790,915 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00281 NCBI chr13:94,246,694...94,261,133
Ensembl chr13:113,315,868...113,329,995 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00281 NCBI chr  X:144,316,192...144,505,773
Ensembl chr  X:154,156,873...154,341,317 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00281 NCBI chr  X:128,684,709...128,719,020
Ensembl chr  X:138,934,167...138,967,087 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00281 NCBI chr 4:146,949,680...146,957,291 JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00281 NCBI chr 4:146,929,561...146,937,665
Ensembl chr 4:158,747,659...158,755,766 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00281 NCBI chr 4:146,970,671...146,979,348
Ensembl chr 4:158,788,966...158,797,237 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00281 NCBI chr2A:85,599,227...85,612,274
Ensembl chr2A:87,152,111...87,164,567 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00281 NCBI chr 4:178,398,359...178,429,448
Ensembl chr 4:190,604,901...190,636,300 		JBrowse link
G LOC100982214 plasminogen ISO SMPDB SMP:00281 NCBI chr 6:158,662,192...158,713,413
Ensembl chr 6:163,673,464...163,736,777 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00281 NCBI chr 8:41,419,415...41,451,951
Ensembl chr 8:38,864,918...38,897,779 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00281 NCBI chr16:23,871,756...23,876,599
Ensembl chr16:31,459,560...31,464,897 		JBrowse link
argatroban pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00276 NCBI chr17:44,274,349...44,291,764
Ensembl chr17:49,150,677...49,166,677 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00276 NCBI chr13:94,263,202...94,289,612
Ensembl chr13:113,332,124...113,358,660 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00276 NCBI chr 4:178,436,865...178,459,568
Ensembl chr 4:190,643,733...190,666,512 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00276 NCBI chr 5:172,703,724...172,711,618
Ensembl chr 5:179,766,243...179,773,485 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00276 NCBI chr 6:5,978,505...6,156,705
Ensembl chr 6:6,157,926...6,513,961 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00276 NCBI chr 1:172,623,336...172,651,945
Ensembl chr 1:176,937,158...176,965,773 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00276 NCBI chr11:46,669,925...46,690,391
Ensembl chr11:47,227,891...47,249,157 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00276 NCBI chr 1:97,190,381...97,203,076
Ensembl chr 1:95,918,502...95,931,050 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00276 NCBI chr 1:144,996,757...145,070,046
Ensembl chr 1:148,718,897...148,790,915 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00276 NCBI chr13:94,246,694...94,261,133
Ensembl chr13:113,315,868...113,329,995 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00276 NCBI chr  X:144,316,192...144,505,773
Ensembl chr  X:154,156,873...154,341,317 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00276 NCBI chr  X:128,684,709...128,719,020
Ensembl chr  X:138,934,167...138,967,087 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00276 NCBI chr 4:146,949,680...146,957,291 JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00276 NCBI chr 4:146,929,561...146,937,665
Ensembl chr 4:158,747,659...158,755,766 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00276 NCBI chr 4:146,970,671...146,979,348
Ensembl chr 4:158,788,966...158,797,237 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00276 NCBI chr2A:85,599,227...85,612,274
Ensembl chr2A:87,152,111...87,164,567 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00276 NCBI chr 4:178,398,359...178,429,448
Ensembl chr 4:190,604,901...190,636,300 		JBrowse link
G LOC100982214 plasminogen ISO SMPDB SMP:00276 NCBI chr 6:158,662,192...158,713,413
Ensembl chr 6:163,673,464...163,736,777 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00276 NCBI chr 8:41,419,415...41,451,951
Ensembl chr 8:38,864,918...38,897,779 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00276 NCBI chr16:23,871,756...23,876,599
Ensembl chr16:31,459,560...31,464,897 		JBrowse link
bivalirudin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00277 NCBI chr17:44,274,349...44,291,764
Ensembl chr17:49,150,677...49,166,677 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00277 NCBI chr13:94,263,202...94,289,612
Ensembl chr13:113,332,124...113,358,660 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00277 NCBI chr 4:178,436,865...178,459,568
Ensembl chr 4:190,643,733...190,666,512 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00277 NCBI chr 5:172,703,724...172,711,618
Ensembl chr 5:179,766,243...179,773,485 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00277 NCBI chr 6:5,978,505...6,156,705
Ensembl chr 6:6,157,926...6,513,961 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00277 NCBI chr 1:172,623,336...172,651,945
Ensembl chr 1:176,937,158...176,965,773 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00277 NCBI chr11:46,669,925...46,690,391
Ensembl chr11:47,227,891...47,249,157 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00277 NCBI chr 1:97,190,381...97,203,076
Ensembl chr 1:95,918,502...95,931,050 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00277 NCBI chr 1:144,996,757...145,070,046
Ensembl chr 1:148,718,897...148,790,915 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00277 NCBI chr13:94,246,694...94,261,133
Ensembl chr13:113,315,868...113,329,995 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00277 NCBI chr  X:144,316,192...144,505,773
Ensembl chr  X:154,156,873...154,341,317 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00277 NCBI chr  X:128,684,709...128,719,020
Ensembl chr  X:138,934,167...138,967,087 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00277 NCBI chr 4:146,949,680...146,957,291 JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00277 NCBI chr 4:146,929,561...146,937,665
Ensembl chr 4:158,747,659...158,755,766 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00277 NCBI chr 4:146,970,671...146,979,348
Ensembl chr 4:158,788,966...158,797,237 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00277 NCBI chr2A:85,599,227...85,612,274
Ensembl chr2A:87,152,111...87,164,567 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00277 NCBI chr 4:178,398,359...178,429,448
Ensembl chr 4:190,604,901...190,636,300 		JBrowse link
G LOC100982214 plasminogen ISO SMPDB SMP:00277 NCBI chr 6:158,662,192...158,713,413
Ensembl chr 6:163,673,464...163,736,777 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00277 NCBI chr 8:41,419,415...41,451,951
Ensembl chr 8:38,864,918...38,897,779 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00277 NCBI chr16:23,871,756...23,876,599
Ensembl chr16:31,459,560...31,464,897 		JBrowse link
cilostazol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDE4D phosphodiesterase 4D ISO SMPDB SMP:00263 NCBI chr 5:53,510,287...55,039,181
Ensembl chr 5:55,749,214...56,670,111 		JBrowse link
clopidogrel pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 ISO SMPDB SMP:00260 NCBI chr 7:79,497,536...79,706,277
Ensembl chr 7:93,147,950...93,243,238 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 ISO SMPDB SMP:00260 NCBI chr15:53,692,877...53,699,279
Ensembl chr15:73,311,720...73,319,447 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 ISO SMPDB SMP:00260 NCBI chr19:38,003,083...38,028,980
Ensembl chr19:46,509,370...46,534,672 		JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 ISO SMPDB SMP:00260 NCBI chr10:91,375,255...91,465,215
Ensembl chr10:94,884,472...94,970,065 		JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 ISO SMPDB SMP:00260 NCBI chr10:91,547,865...91,598,918
Ensembl chr10:95,022,482...95,105,653 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 ISO SMPDB SMP:00260 NCBI chr 7:91,797,037...91,824,696
Ensembl chr 7:105,230,666...105,258,401 		JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 ISO SMPDB SMP:00260 NCBI chr 7:91,621,561...91,654,164
Ensembl chr 7:105,123,437...105,155,322 		JBrowse link
G P2RY12 purinergic receptor P2Y12 ISO SMPDB SMP:00260 NCBI chr 3:148,364,151...148,412,231 JBrowse link
G PON1 paraoxonase 1 ISO SMPDB SMP:00260 NCBI chr 7:87,253,476...87,279,650
Ensembl chr 7:100,841,286...100,867,493 		JBrowse link
clopidogrel pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 ISO SMPDB SMP:00610 NCBI chr 7:79,497,536...79,706,277
Ensembl chr 7:93,147,950...93,243,238 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 ISO SMPDB SMP:00610 NCBI chr15:53,692,877...53,699,279
Ensembl chr15:73,311,720...73,319,447 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 ISO SMPDB SMP:00610 NCBI chr19:38,003,083...38,028,980
Ensembl chr19:46,509,370...46,534,672 		JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 ISO SMPDB SMP:00610 NCBI chr10:91,375,255...91,465,215
Ensembl chr10:94,884,472...94,970,065 		JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 ISO SMPDB SMP:00610 NCBI chr10:91,547,865...91,598,918
Ensembl chr10:95,022,482...95,105,653 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 ISO SMPDB SMP:00610 NCBI chr 7:91,797,037...91,824,696
Ensembl chr 7:105,230,666...105,258,401 		JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 ISO SMPDB SMP:00610 NCBI chr 7:91,621,561...91,654,164
Ensembl chr 7:105,123,437...105,155,322 		JBrowse link
G P2RY12 purinergic receptor P2Y12 ISO SMPDB SMP:00610 NCBI chr 3:148,364,151...148,412,231 JBrowse link
G PON1 paraoxonase 1 ISO SMPDB SMP:00610 NCBI chr 7:87,253,476...87,279,650
Ensembl chr 7:100,841,286...100,867,493 		JBrowse link
dicoumarol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00270 SMP:00656 NCBI chr17:44,274,349...44,291,764
Ensembl chr17:49,150,677...49,166,677 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00270 SMP:00656 NCBI chr13:94,263,202...94,289,612
Ensembl chr13:113,332,124...113,358,660 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00270 SMP:00656 NCBI chr 4:178,436,865...178,459,568
Ensembl chr 4:190,643,733...190,666,512 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00270 SMP:00656 NCBI chr 5:172,703,724...172,711,618
Ensembl chr 5:179,766,243...179,773,485 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00270 SMP:00656 NCBI chr 6:5,978,505...6,156,705
Ensembl chr 6:6,157,926...6,513,961 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00270 SMP:00656 NCBI chr 1:172,623,336...172,651,945
Ensembl chr 1:176,937,158...176,965,773 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00270 SMP:00656 NCBI chr11:46,669,925...46,690,391
Ensembl chr11:47,227,891...47,249,157 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00270 SMP:00656 NCBI chr 1:97,190,381...97,203,076
Ensembl chr 1:95,918,502...95,931,050 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00270 SMP:00656 NCBI chr 1:144,996,757...145,070,046
Ensembl chr 1:148,718,897...148,790,915 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00270 SMP:00656 NCBI chr13:94,246,694...94,261,133
Ensembl chr13:113,315,868...113,329,995 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00270 SMP:00656 NCBI chr  X:144,316,192...144,505,773
Ensembl chr  X:154,156,873...154,341,317 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00270 SMP:00656 NCBI chr  X:128,684,709...128,719,020
Ensembl chr  X:138,934,167...138,967,087 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00270 SMP:00656 NCBI chr 4:146,949,680...146,957,291 JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00270 SMP:00656 NCBI chr 4:146,929,561...146,937,665
Ensembl chr 4:158,747,659...158,755,766 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00270 SMP:00656 NCBI chr 4:146,970,671...146,979,348
Ensembl chr 4:158,788,966...158,797,237 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00270 SMP:00656 NCBI chr2A:85,599,227...85,612,274
Ensembl chr2A:87,152,111...87,164,567 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00270 SMP:00656 NCBI chr 4:178,398,359...178,429,448
Ensembl chr 4:190,604,901...190,636,300 		JBrowse link
G LOC100982214 plasminogen ISO SMPDB SMP:00270 SMP:00656 NCBI chr 6:158,662,192...158,713,413
Ensembl chr 6:163,673,464...163,736,777 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00270 SMP:00656 NCBI chr 8:41,419,415...41,451,951
Ensembl chr 8:38,864,918...38,897,779 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00270 SMP:00656 NCBI chr16:23,871,756...23,876,599
Ensembl chr16:31,459,560...31,464,897 		JBrowse link
dipyridamole pharmacodyamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDE4D phosphodiesterase 4D ISO SMPDB SMP:00264 NCBI chr 5:53,510,287...55,039,181
Ensembl chr 5:55,749,214...56,670,111 		JBrowse link
enoxaparin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00272 NCBI chr17:44,274,349...44,291,764
Ensembl chr17:49,150,677...49,166,677 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00272 NCBI chr13:94,263,202...94,289,612
Ensembl chr13:113,332,124...113,358,660 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00272 NCBI chr 4:178,436,865...178,459,568
Ensembl chr 4:190,643,733...190,666,512 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00272 NCBI chr 5:172,703,724...172,711,618
Ensembl chr 5:179,766,243...179,773,485 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00272 NCBI chr 6:5,978,505...6,156,705
Ensembl chr 6:6,157,926...6,513,961 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00272 NCBI chr 1:172,623,336...172,651,945
Ensembl chr 1:176,937,158...176,965,773 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00272 NCBI chr11:46,669,925...46,690,391
Ensembl chr11:47,227,891...47,249,157 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00272 NCBI chr 1:97,190,381...97,203,076
Ensembl chr 1:95,918,502...95,931,050 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00272 NCBI chr 1:144,996,757...145,070,046
Ensembl chr 1:148,718,897...148,790,915 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00272 NCBI chr13:94,246,694...94,261,133
Ensembl chr13:113,315,868...113,329,995 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00272 NCBI chr  X:144,316,192...144,505,773
Ensembl chr  X:154,156,873...154,341,317 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00272 NCBI chr  X:128,684,709...128,719,020
Ensembl chr  X:138,934,167...138,967,087 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00272 NCBI chr 4:146,949,680...146,957,291 JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00272 NCBI chr 4:146,929,561...146,937,665
Ensembl chr 4:158,747,659...158,755,766 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00272 NCBI chr 4:146,970,671...146,979,348
Ensembl chr 4:158,788,966...158,797,237 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00272 NCBI chr2A:85,599,227...85,612,274
Ensembl chr2A:87,152,111...87,164,567 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00272 NCBI chr 4:178,398,359...178,429,448
Ensembl chr 4:190,604,901...190,636,300 		JBrowse link
G LOC100982214 plasminogen ISO SMPDB SMP:00272 NCBI chr 6:158,662,192...158,713,413
Ensembl chr 6:163,673,464...163,736,777 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00272 NCBI chr 8:41,419,415...41,451,951
Ensembl chr 8:38,864,918...38,897,779 		JBrowse link
G SERPINC1 serpin family C member 1 ISO SMPDB SMP:00272 NCBI chr 1:149,421,737...149,435,301
Ensembl chr 1:153,126,031...153,139,369 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00272 NCBI chr16:23,871,756...23,876,599
Ensembl chr16:31,459,560...31,464,897 		JBrowse link
eptifibatide pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGA2B integrin subunit alpha 2b ISO SMPDB SMP:00266 NCBI chr17:13,009,514...13,027,289
Ensembl chr17:13,176,843...13,193,269 		JBrowse link
G ITGB3 integrin subunit beta 3 ISO SMPDB SMP:00266 NCBI chr17:10,134,450...10,194,596
Ensembl chr17:10,353,111...10,392,382 		JBrowse link
fondaparinux pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00273 NCBI chr17:44,274,349...44,291,764
Ensembl chr17:49,150,677...49,166,677 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00273 NCBI chr13:94,263,202...94,289,612
Ensembl chr13:113,332,124...113,358,660 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00273 NCBI chr 4:178,436,865...178,459,568
Ensembl chr 4:190,643,733...190,666,512 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00273 NCBI chr 5:172,703,724...172,711,618
Ensembl chr 5:179,766,243...179,773,485 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00273 NCBI chr 6:5,978,505...6,156,705
Ensembl chr 6:6,157,926...6,513,961 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00273 NCBI chr 1:172,623,336...172,651,945
Ensembl chr 1:176,937,158...176,965,773 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00273 NCBI chr11:46,669,925...46,690,391
Ensembl chr11:47,227,891...47,249,157 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00273 NCBI chr 1:97,190,381...97,203,076
Ensembl chr 1:95,918,502...95,931,050 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00273 NCBI chr 1:144,996,757...145,070,046
Ensembl chr 1:148,718,897...148,790,915 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00273 NCBI chr13:94,246,694...94,261,133
Ensembl chr13:113,315,868...113,329,995 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00273 NCBI chr  X:144,316,192...144,505,773
Ensembl chr  X:154,156,873...154,341,317 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00273 NCBI chr  X:128,684,709...128,719,020
Ensembl chr  X:138,934,167...138,967,087 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00273 NCBI chr 4:146,949,680...146,957,291 JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00273 NCBI chr 4:146,929,561...146,937,665
Ensembl chr 4:158,747,659...158,755,766 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00273 NCBI chr 4:146,970,671...146,979,348
Ensembl chr 4:158,788,966...158,797,237 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00273 NCBI chr2A:85,599,227...85,612,274
Ensembl chr2A:87,152,111...87,164,567 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00273 NCBI chr 4:178,398,359...178,429,448
Ensembl chr 4:190,604,901...190,636,300 		JBrowse link
G LOC100982214 plasminogen ISO SMPDB SMP:00273 NCBI chr 6:158,662,192...158,713,413
Ensembl chr 6:163,673,464...163,736,777 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00273 NCBI chr 8:41,419,415...41,451,951
Ensembl chr 8:38,864,918...38,897,779 		JBrowse link
G SERPINC1 serpin family C member 1 ISO SMPDB SMP:00273 NCBI chr 1:149,421,737...149,435,301
Ensembl chr 1:153,126,031...153,139,369 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00273 NCBI chr16:23,871,756...23,876,599
Ensembl chr16:31,459,560...31,464,897 		JBrowse link
heparin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00274 NCBI chr17:44,274,349...44,291,764
Ensembl chr17:49,150,677...49,166,677 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00274 NCBI chr13:94,263,202...94,289,612
Ensembl chr13:113,332,124...113,358,660 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00274 NCBI chr 4:178,436,865...178,459,568
Ensembl chr 4:190,643,733...190,666,512 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00274 NCBI chr 5:172,703,724...172,711,618
Ensembl chr 5:179,766,243...179,773,485 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00274 NCBI chr 6:5,978,505...6,156,705
Ensembl chr 6:6,157,926...6,513,961 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00274 NCBI chr 1:172,623,336...172,651,945
Ensembl chr 1:176,937,158...176,965,773 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00274 NCBI chr11:46,669,925...46,690,391
Ensembl chr11:47,227,891...47,249,157 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00274 NCBI chr 1:97,190,381...97,203,076
Ensembl chr 1:95,918,502...95,931,050 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00274 NCBI chr 1:144,996,757...145,070,046
Ensembl chr 1:148,718,897...148,790,915 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00274 NCBI chr13:94,246,694...94,261,133
Ensembl chr13:113,315,868...113,329,995 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00274 NCBI chr  X:144,316,192...144,505,773
Ensembl chr  X:154,156,873...154,341,317 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00274 NCBI chr  X:128,684,709...128,719,020
Ensembl chr  X:138,934,167...138,967,087 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00274 NCBI chr 4:146,949,680...146,957,291 JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00274 NCBI chr 4:146,929,561...146,937,665
Ensembl chr 4:158,747,659...158,755,766 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00274 NCBI chr 4:146,970,671...146,979,348
Ensembl chr 4:158,788,966...158,797,237 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00274 NCBI chr2A:85,599,227...85,612,274
Ensembl chr2A:87,152,111...87,164,567 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00274 NCBI chr 4:178,398,359...178,429,448
Ensembl chr 4:190,604,901...190,636,300 		JBrowse link
G LOC100982214 plasminogen ISO SMPDB SMP:00274 NCBI chr 6:158,662,192...158,713,413
Ensembl chr 6:163,673,464...163,736,777 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00274 NCBI chr 8:41,419,415...41,451,951
Ensembl chr 8:38,864,918...38,897,779 		JBrowse link
G SERPINC1 serpin family C member 1 ISO SMPDB SMP:00274 NCBI chr 1:149,421,737...149,435,301
Ensembl chr 1:153,126,031...153,139,369 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00274 NCBI chr16:23,871,756...23,876,599
Ensembl chr16:31,459,560...31,464,897 		JBrowse link
phenindione pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00655 NCBI chr17:44,274,349...44,291,764
Ensembl chr17:49,150,677...49,166,677 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00655 NCBI chr13:94,263,202...94,289,612
Ensembl chr13:113,332,124...113,358,660 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00655 NCBI chr 4:178,436,865...178,459,568
Ensembl chr 4:190,643,733...190,666,512 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00655 NCBI chr 5:172,703,724...172,711,618
Ensembl chr 5:179,766,243...179,773,485 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00655 NCBI chr 6:5,978,505...6,156,705
Ensembl chr 6:6,157,926...6,513,961 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00655 NCBI chr 1:172,623,336...172,651,945
Ensembl chr 1:176,937,158...176,965,773 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00655 NCBI chr11:46,669,925...46,690,391
Ensembl chr11:47,227,891...47,249,157 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00655 NCBI chr 1:97,190,381...97,203,076
Ensembl chr 1:95,918,502...95,931,050 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00655 NCBI chr 1:144,996,757...145,070,046
Ensembl chr 1:148,718,897...148,790,915 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00655 NCBI chr13:94,246,694...94,261,133
Ensembl chr13:113,315,868...113,329,995 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00655 NCBI chr  X:144,316,192...144,505,773
Ensembl chr  X:154,156,873...154,341,317 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00655 NCBI chr  X:128,684,709...128,719,020
Ensembl chr  X:138,934,167...138,967,087 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00655 NCBI chr 4:146,949,680...146,957,291 JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00655 NCBI chr 4:146,929,561...146,937,665
Ensembl chr 4:158,747,659...158,755,766 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00655 NCBI chr 4:146,970,671...146,979,348
Ensembl chr 4:158,788,966...158,797,237 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00655 NCBI chr2A:85,599,227...85,612,274
Ensembl chr2A:87,152,111...87,164,567 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00655 NCBI chr 4:178,398,359...178,429,448
Ensembl chr 4:190,604,901...190,636,300 		JBrowse link
G LOC100982214 plasminogen ISO SMPDB SMP:00655 NCBI chr 6:158,662,192...158,713,413
Ensembl chr 6:163,673,464...163,736,777 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00655 NCBI chr 8:41,419,415...41,451,951
Ensembl chr 8:38,864,918...38,897,779 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00655 NCBI chr16:23,871,756...23,876,599
Ensembl chr16:31,459,560...31,464,897 		JBrowse link
reteplase pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00285 NCBI chr17:44,274,349...44,291,764
Ensembl chr17:49,150,677...49,166,677 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00285 NCBI chr13:94,263,202...94,289,612
Ensembl chr13:113,332,124...113,358,660 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00285 NCBI chr 4:178,436,865...178,459,568
Ensembl chr 4:190,643,733...190,666,512 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00285 NCBI chr 5:172,703,724...172,711,618
Ensembl chr 5:179,766,243...179,773,485 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00285 NCBI chr 6:5,978,505...6,156,705
Ensembl chr 6:6,157,926...6,513,961 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00285 NCBI chr 1:172,623,336...172,651,945
Ensembl chr 1:176,937,158...176,965,773 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00285 NCBI chr11:46,669,925...46,690,391
Ensembl chr11:47,227,891...47,249,157 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00285 NCBI chr 1:97,190,381...97,203,076
Ensembl chr 1:95,918,502...95,931,050 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00285 NCBI chr 1:144,996,757...145,070,046
Ensembl chr 1:148,718,897...148,790,915 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00285 NCBI chr13:94,246,694...94,261,133
Ensembl chr13:113,315,868...113,329,995 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00285 NCBI chr  X:144,316,192...144,505,773
Ensembl chr  X:154,156,873...154,341,317 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00285 NCBI chr  X:128,684,709...128,719,020
Ensembl chr  X:138,934,167...138,967,087 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00285 NCBI chr 4:146,949,680...146,957,291 JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00285 NCBI chr 4:146,929,561...146,937,665
Ensembl chr 4:158,747,659...158,755,766 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00285 NCBI chr 4:146,970,671...146,979,348
Ensembl chr 4:158,788,966...158,797,237 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00285 NCBI chr2A:85,599,227...85,612,274
Ensembl chr2A:87,152,111...87,164,567 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00285 NCBI chr 4:178,398,359...178,429,448
Ensembl chr 4:190,604,901...190,636,300 		JBrowse link
G LOC100982214 plasminogen ISO SMPDB SMP:00285 NCBI chr 6:158,662,192...158,713,413
Ensembl chr 6:163,673,464...163,736,777 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00285 NCBI chr 8:41,419,415...41,451,951
Ensembl chr 8:38,864,918...38,897,779 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00285 NCBI chr16:23,871,756...23,876,599
Ensembl chr16:31,459,560...31,464,897 		JBrowse link
salicylic acid pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C3 aldo-keto reductase family 1 member C3 ISO SMPDB SMP:00709 NCBI chr10:5,079,580...5,157,572
Ensembl chr10:5,081,214...5,139,812 		JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO SMPDB SMP:00709 NCBI chr17:7,026,839...7,041,598
Ensembl chr17:7,014,591...7,029,602 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00709 NCBI chr17:43,569,858...43,588,039
Ensembl chr17:48,302,450...48,317,029 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00709 NCBI chr17:4,686,339...4,696,877
Ensembl chr17:4,677,125...4,687,669 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00709 NCBI chr10:42,461,398...42,531,576
Ensembl chr10:45,639,946...45,710,016 		JBrowse link
G CBR1 carbonyl reductase 1 ISO SMPDB SMP:00709 NCBI chr21:22,440,726...22,443,950
Ensembl chr21:35,800,177...35,803,458 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 ISO SMPDB SMP:00709 NCBI chr19:38,003,083...38,028,980
Ensembl chr19:46,509,370...46,534,672 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 ISO SMPDB SMP:00709 NCBI chr10:91,646,387...91,679,998
Ensembl chr10:95,157,661...95,186,620 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO SMPDB SMP:00709 Ensembl chr10:134,839,025...134,852,719 JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 ISO SMPDB SMP:00709 NCBI chr 1:59,151,079...59,184,625
Ensembl chr 1:60,856,269...60,889,810 		JBrowse link
G CYP2U1 cytochrome P450 family 2 subfamily U member 1 ISO SMPDB SMP:00709 NCBI chr 4:100,436,365...100,458,845
Ensembl chr 4:111,009,198...111,031,269 		JBrowse link
G CYP4A11 cytochrome P450 family 4 subfamily A member 11 ISO SMPDB SMP:00709 NCBI chr 1:46,228,434...46,240,736
Ensembl chr 1:47,583,564...47,594,870 		JBrowse link
G CYP4F3 cytochrome P450 family 4 subfamily F member 3 ISO SMPDB SMP:00709 NCBI chr19:15,162,886...15,182,334
Ensembl chr19:16,146,664...16,165,869 		JBrowse link
G CYP4F8 cytochrome P450 family 4 subfamily F member 8 ISO SMPDB SMP:00709 NCBI chr19:15,134,029...15,150,378
Ensembl chr19:16,118,830...16,133,182 		JBrowse link
G EPHX2 epoxide hydrolase 2 ISO SMPDB SMP:00709 NCBI chr 8:26,761,090...26,818,436
Ensembl chr 8:23,964,094...24,017,749 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO SMPDB SMP:00709 NCBI chr22:5,424,334...5,469,705 JBrowse link
G GPX1 glutathione peroxidase 1 ISO SMPDB SMP:00709 NCBI chr 3:49,280,038...49,281,455
Ensembl chr 3:50,360,947...50,361,826 		JBrowse link
G LOC100971127 arachidonate 15-lipoxygenase type B ISO SMPDB SMP:00709 NCBI chr17:43,609,146...43,619,713
Ensembl chr17:48,340,777...48,350,808 		JBrowse link
G LTA4H leukotriene A4 hydrolase ISO SMPDB SMP:00709 NCBI chr12:93,589,758...93,624,529
Ensembl chr12:96,978,203...97,012,427 		JBrowse link
G LTC4S leukotriene C4 synthase ISO SMPDB SMP:00709 NCBI chr 5:174,946,346...174,950,805 JBrowse link
G PRXL2B peroxiredoxin like 2B ISO SMPDB SMP:00709 NCBI chr 1:1,319,718...1,324,409 JBrowse link
G PTGDS prostaglandin D2 synthase ISO SMPDB SMP:00709 NCBI chr 9:108,037,994...108,042,136
Ensembl chr 9:137,006,601...137,009,680 		JBrowse link
G PTGES prostaglandin E synthase ISO SMPDB SMP:00709 NCBI chr 9:100,865,702...100,880,408
Ensembl chr 9:129,522,547...129,537,020 		JBrowse link
G PTGIS prostaglandin I2 synthase ISO SMPDB SMP:00709 NCBI chr20:45,841,238...45,905,641
Ensembl chr20:46,905,665...46,971,612 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00709 NCBI chr 9:93,495,365...93,517,557
Ensembl chr 9:121,837,095...121,859,283 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00709 NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519 		JBrowse link
G TBXAS1 thromboxane A synthase 1 ISO SMPDB SMP:00709 NCBI chr 7:131,772,947...131,958,647
Ensembl chr 7:144,255,211...144,439,523 		JBrowse link
ticlopidine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2RY12 purinergic receptor P2Y12 ISO SMPDB SMP:00261 NCBI chr 3:148,364,151...148,412,231 JBrowse link
ticlopidine pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2RY12 purinergic receptor P2Y12 ISO SMPDB SMP:00611 NCBI chr 3:148,364,151...148,412,231 JBrowse link
tirofiban pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGA2B integrin subunit alpha 2b ISO SMPDB SMP:00267 NCBI chr17:13,009,514...13,027,289
Ensembl chr17:13,176,843...13,193,269 		JBrowse link
G ITGB3 integrin subunit beta 3 ISO SMPDB SMP:00267 NCBI chr17:10,134,450...10,194,596
Ensembl chr17:10,353,111...10,392,382 		JBrowse link
warfarin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00268 NCBI chr17:44,274,349...44,291,764
Ensembl chr17:49,150,677...49,166,677 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00268 NCBI chr13:94,263,202...94,289,612
Ensembl chr13:113,332,124...113,358,660 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00268 NCBI chr 4:178,436,865...178,459,568
Ensembl chr 4:190,643,733...190,666,512 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00268 NCBI chr 5:172,703,724...172,711,618
Ensembl chr 5:179,766,243...179,773,485 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00268 NCBI chr 6:5,978,505...6,156,705
Ensembl chr 6:6,157,926...6,513,961 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00268 NCBI chr 1:172,623,336...172,651,945
Ensembl chr 1:176,937,158...176,965,773 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00268 NCBI chr11:46,669,925...46,690,391
Ensembl chr11:47,227,891...47,249,157 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00268 NCBI chr 1:97,190,381...97,203,076
Ensembl chr 1:95,918,502...95,931,050 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00268 NCBI chr 1:144,996,757...145,070,046
Ensembl chr 1:148,718,897...148,790,915 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00268 NCBI chr13:94,246,694...94,261,133
Ensembl chr13:113,315,868...113,329,995 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00268 NCBI chr  X:144,316,192...144,505,773
Ensembl chr  X:154,156,873...154,341,317 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00268 NCBI chr  X:128,684,709...128,719,020
Ensembl chr  X:138,934,167...138,967,087 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00268 NCBI chr 4:146,949,680...146,957,291 JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00268 NCBI chr 4:146,929,561...146,937,665
Ensembl chr 4:158,747,659...158,755,766 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00268 NCBI chr 4:146,970,671...146,979,348
Ensembl chr 4:158,788,966...158,797,237 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00268 NCBI chr2A:85,599,227...85,612,274
Ensembl chr2A:87,152,111...87,164,567 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00268 NCBI chr 4:178,398,359...178,429,448
Ensembl chr 4:190,604,901...190,636,300 		JBrowse link
G LOC100982214 plasminogen ISO SMPDB SMP:00268 NCBI chr 6:158,662,192...158,713,413
Ensembl chr 6:163,673,464...163,736,777 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00268 NCBI chr 8:41,419,415...41,451,951
Ensembl chr 8:38,864,918...38,897,779 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB
RGD		 PMID:26287237 RGD:11354881 SMP:00268 NCBI chr16:23,871,756...23,876,599
Ensembl chr16:31,459,560...31,464,897 		JBrowse link
warfarin pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO RGD PMID:26655108 RGD:11354883 NCBI chr15:53,664,968...53,672,277
Ensembl chr15:73,284,566...73,290,636 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 ISO RGD PMID:26655108 RGD:11354883 NCBI chr15:53,692,877...53,699,279
Ensembl chr15:73,311,720...73,319,447 		JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 ISO RGD PMID:26655108 RGD:11354883 NCBI chr10:91,375,255...91,465,215
Ensembl chr10:94,884,472...94,970,065 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 ISO RGD PMID:26655108 RGD:11354883 NCBI chr10:91,646,387...91,679,998
Ensembl chr10:95,157,661...95,186,620 		JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 ISO RGD PMID:26655108 RGD:11354883 NCBI chr10:91,547,865...91,598,918
Ensembl chr10:95,022,482...95,105,653 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 ISO RGD PMID:26655108 RGD:11354883 NCBI chr 7:91,797,037...91,824,696
Ensembl chr 7:105,230,666...105,258,401 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4064
    drug pathway 395
      blood and blood forming organs drug pathway 60
        antithrombotic drug pathway 60
          anticoagulant drug pathway + 27
          antiplatelet drug pathway + 38
          other antithrombotic drug pathway + 21
          thrombolytic drug pathway + 20
paths to the root