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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:adefovir drug pathway
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Accession:PW:0001616 term browser browse the term
Definition:The pharmacokinetics and pharmacodynamics pathway of adefovir, an anti-viral drug used for the treatment of hepatitis B. It is administered as adefovir dipivoxil prodrug. Once metabolized, it acts as a nucleotide analog reverse transcriptase inhibitor.


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adefovir pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ak1 adenylate kinase 1 ISO SMPDB SMP:00629 NCBI chrNW_004624760:7,684,098...7,693,051
Ensembl chrNW_004624760:7,684,109...7,693,405
JBrowse link
G Ak2 adenylate kinase 2 ISO SMPDB SMP:00629 NCBI chrNW_004624764:16,089,357...16,113,275 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 3917
    drug pathway 349
      anti-infective drug pathway 18
        adefovir drug pathway 2
          adefovir pharmacodynamics pathway 0
          adefovir pharmacokinetics pathway 2
paths to the root