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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:adefovir drug pathway
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Accession:PW:0001616 term browser browse the term
Definition:The pharmacokinetics and pharmacodynamics pathway of adefovir, an anti-viral drug used for the treatment of hepatitis B. It is administered as adefovir dipivoxil prodrug. Once metabolized, it acts as a nucleotide analog reverse transcriptase inhibitor.



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adefovir pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AK1 adenylate kinase 1 ISO SMPDB SMP:00629 NCBI chr 9:55,539,179...55,548,132
Ensembl chr 9:55,539,260...55,548,132
JBrowse link
G AK2 adenylate kinase 2 ISO SMPDB SMP:00629 NCBI chr 2:68,342,769...68,371,769
Ensembl chr 2:68,350,057...68,371,090
JBrowse link
G NME1 non-metastatic cells 1, protein (NM23A) expressed in ISO SMPDB SMP:00629 NCBI chr 9:26,990,336...26,998,895
Ensembl chr 9:26,990,469...26,998,955
JBrowse link
G NME2 non-metastatic cells 2, protein (NM23B) expressed in ISO SMPDB SMP:00629 NCBI chr 9:27,002,114...27,005,740
Ensembl chr 9:27,001,733...27,015,934
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4046
    drug pathway 379
      anti-infective drug pathway 27
        adefovir drug pathway 4
          adefovir pharmacodynamics pathway 0
          adefovir pharmacokinetics pathway 4
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