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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:adefovir drug pathway
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Accession:PW:0001616 term browser browse the term
Definition:The pharmacokinetics and pharmacodynamics pathway of adefovir, an anti-viral drug used for the treatment of hepatitis B. It is administered as adefovir dipivoxil prodrug. Once metabolized, it acts as a nucleotide analog reverse transcriptase inhibitor.

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adefovir pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ak1 adenylate kinase 1 ISO SMPDB SMP:00629 NCBI chrNW_004955419:799,415...807,138
Ensembl chrNW_004955419:799,410...811,029 		JBrowse link
G Ak2 adenylate kinase 2 ISO SMPDB SMP:00629 NCBI chrNW_004955452:11,254,853...11,275,587 JBrowse link
Term paths to the root
Path 1
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  pathway 3924
    drug pathway 348
      anti-infective drug pathway 18
        adefovir drug pathway 2
          adefovir pharmacodynamics pathway 0
          adefovir pharmacokinetics pathway 2
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