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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:endocrine system disease pathway
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Accession:PW:0001547 term browser browse the term


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adrenoleukodystrophy pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcd1 ATP binding cassette subfamily D member 1 ISO SMPDB SMP:00516 NCBI chr  X:157,073,860...157,095,652
Ensembl chr  X:157,072,736...157,095,274
JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 ISO SMPDB SMP:00516 NCBI chr 7:132,294,564...132,343,169
Ensembl chr 7:132,294,562...132,343,169
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 ISO SMPDB SMP:00516 NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 ISO SMPDB SMP:00516 NCBI chr 5:127,505,646...127,523,016
Ensembl chr 5:127,505,614...127,523,089
JBrowse link
G Crat carnitine O-acetyltransferase ISO SMPDB SMP:00516 NCBI chr 3:8,967,984...8,981,959
Ensembl chr 3:8,968,417...8,981,362
JBrowse link
G Crot carnitine O-octanoyltransferase ISO SMPDB SMP:00516 NCBI chr 4:22,079,837...22,116,265
Ensembl chr 4:22,081,604...22,116,265
JBrowse link
G Pex11g peroxisomal biogenesis factor 11 gamma ISO SMPDB SMP:00516 NCBI chr12:2,000,426...2,007,516
Ensembl chr12:2,000,427...2,007,516
JBrowse link
G Pex13 peroxisomal biogenesis factor 13 ISO SMPDB SMP:00516 NCBI chr14:108,394,299...108,411,994
Ensembl chr14:108,394,303...108,412,823
JBrowse link
G Pex14 peroxisomal biogenesis factor 14 ISO SMPDB SMP:00516 NCBI chr 5:165,782,895...165,918,445
Ensembl chr 5:165,782,895...165,918,445
JBrowse link
G Slc25a20 solute carrier family 25 member 20 ISO SMPDB SMP:00516 NCBI chr 8:117,455,308...117,476,762
Ensembl chr 8:117,455,262...117,476,734
JBrowse link
diabetes mellitus pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 IDA RGD PMID:18025464 RGD:2301904 NCBI chr 1:102,110,708...102,191,287
Ensembl chr 1:102,110,708...102,191,287
JBrowse link
G Sod3 superoxide dismutase 3 ISO RGD PMID:12830380 RGD:1581299 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
diabetic nephropathy pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b1 aldo-keto reductase family 1 member B ISS RGD PMID:9215310 RGD:734542 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Spp1 secreted phosphoprotein 1 IDA RGD PMID:16528250 RGD:1581322 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
maturity-onset diabetes of the young pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhlha15 basic helix-loop-helix family, member a15 IEA KEGG rno:04950 NCBI chr12:12,403,385...12,409,103
Ensembl chr12:12,403,385...12,407,561
JBrowse link
G Foxa2 forkhead box A2 IEA KEGG rno:04950 NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481
JBrowse link
G Foxa3 forkhead box A3 IEA KEGG rno:04950 NCBI chr 1:79,921,292...79,930,219
Ensembl chr 1:79,920,752...79,930,263
JBrowse link
G Gck glucokinase IEA KEGG rno:04950 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
JBrowse link
G Hes1 hes family bHLH transcription factor 1 IEA KEGG rno:04950 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hhex hematopoietically expressed homeobox IEA KEGG rno:04950 NCBI chr 1:256,101,994...256,107,581
Ensembl chr 1:256,101,903...256,107,649
JBrowse link
G Hnf1a HNF1 homeobox A IEA KEGG rno:04950 NCBI chr12:47,407,811...47,433,342
Ensembl chr12:47,407,811...47,433,342
JBrowse link
G Hnf1b HNF1 homeobox B IEA KEGG rno:04950 NCBI chr10:71,159,863...71,218,902
Ensembl chr10:71,159,869...71,218,902
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha IEA KEGG rno:04950 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
JBrowse link
G Hnf4g hepatocyte nuclear factor 4, gamma IEA KEGG rno:04950 NCBI chr 2:100,225,880...100,372,710
Ensembl chr 2:100,225,888...100,372,252
JBrowse link
G Iapp islet amyloid polypeptide IEA KEGG rno:04950 NCBI chr 4:176,509,863...176,517,903
Ensembl chr 4:176,510,696...176,516,083
JBrowse link
G Ins1 insulin 1 IEA KEGG rno:04950 NCBI chr 1:272,799,784...272,800,351
Ensembl chr 1:272,799,784...272,800,347
JBrowse link
G Ins2 insulin 2 IEA KEGG rno:04950 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Mafa MAF bZIP transcription factor A IEA KEGG rno:04950 NCBI chr 7:116,779,368...116,781,815
Ensembl chr 7:116,780,681...116,781,766
JBrowse link
G Mnx1 motor neuron and pancreas homeobox 1 IEA KEGG rno:04950 NCBI chr 4:2,376,350...2,381,308
Ensembl chr 4:2,376,958...2,381,271
JBrowse link
G Neurod1 neuronal differentiation 1 IEA KEGG rno:04950 NCBI chr 3:66,414,314...66,417,617
Ensembl chr 3:66,414,308...66,417,741
JBrowse link
G Neurog3 neurogenin 3 IEA KEGG rno:04950 NCBI chr20:31,761,419...31,762,893
Ensembl chr20:31,761,405...31,762,893
JBrowse link
G Nkx2-2 NK2 homeobox 2 IEA KEGG rno:04950 NCBI chr 3:141,408,460...141,419,083
Ensembl chr 3:141,408,798...141,411,170
JBrowse link
G Nkx6-1 NK6 homeobox 1 IEA KEGG rno:04950 NCBI chr14:9,555,264...9,562,197
Ensembl chr14:9,555,264...9,562,189
JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 IEA KEGG rno:04950 NCBI chr13:53,750,470...53,870,288
Ensembl chr13:53,750,473...53,870,428
JBrowse link
G Onecut1 one cut homeobox 1 IEA KEGG rno:04950 NCBI chr 8:81,765,779...81,799,894
Ensembl chr 8:81,766,041...81,793,577
JBrowse link
G Pax4 paired box 4 IEA KEGG rno:04950 NCBI chr 4:55,735,640...55,753,461
Ensembl chr 4:55,735,682...55,740,627
JBrowse link
G Pax6 paired box 6 IEA KEGG rno:04950 NCBI chr 3:95,700,241...95,728,682
Ensembl chr 3:95,707,386...95,728,624
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 IEA KEGG rno:04950 NCBI chr12:9,496,044...9,501,211
Ensembl chr12:9,496,044...9,501,213
JBrowse link
G Pklr pyruvate kinase L/R IEA KEGG rno:04950 NCBI chr 2:188,449,158...188,458,034
Ensembl chr 2:188,449,210...188,459,592
JBrowse link
G Slc2a2 solute carrier family 2 member 2 IEA KEGG rno:04950 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
JBrowse link
type 1 diabetes mellitus pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox15 arachidonate 15-lipoxygenase ISO RGD PMID:17940120 RGD:5509611 NCBI chr10:56,953,692...56,962,145
Ensembl chr10:56,953,691...56,962,161
JBrowse link
G Cd28 Cd28 molecule IEA KEGG rno:04940 NCBI chr 9:67,546,408...67,573,858
Ensembl chr 9:67,546,408...67,571,871
JBrowse link
G Cd80 Cd80 molecule IEA KEGG rno:04940 NCBI chr11:64,815,201...64,855,293
Ensembl chr11:64,827,635...64,855,353
JBrowse link
G Cd86 CD86 molecule IEA KEGG rno:04940 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cpe carboxypeptidase E IEA KEGG rno:04940 NCBI chr16:26,906,716...27,014,811
Ensembl chr16:26,906,716...27,014,813
JBrowse link
G Fas Fas cell surface death receptor IEA KEGG rno:04940 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand IEA KEGG rno:04940 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Gad1 glutamate decarboxylase 1 IEA KEGG rno:04940 NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157
JBrowse link
G Gad2 glutamate decarboxylase 2 IEA KEGG rno:04940 NCBI chr17:89,171,576...89,234,770
Ensembl chr17:89,171,250...89,238,040
JBrowse link
G Gzmb granzyme B IEA KEGG rno:04940 NCBI chr15:35,413,862...35,417,293
Ensembl chr15:35,413,793...35,417,316
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 IEA KEGG rno:04940 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Ica1 islet cell autoantigen 1 IEA KEGG rno:04940 NCBI chr 4:34,635,509...34,780,187
Ensembl chr 4:34,635,506...34,780,193
JBrowse link
G Ifng interferon gamma IEA KEGG rno:04940 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il12a interleukin 12A IEA KEGG rno:04940 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
JBrowse link
G Il12b interleukin 12B IEA KEGG rno:04940 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il1a interleukin 1 alpha IEA KEGG rno:04940 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta IEA KEGG rno:04940 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 IEA KEGG rno:04940 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Ins1 insulin 1 IEA KEGG rno:04940 NCBI chr 1:272,799,784...272,800,351
Ensembl chr 1:272,799,784...272,800,347
JBrowse link
G Ins2 insulin 2 IEA KEGG rno:04940 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Lta lymphotoxin alpha IEA KEGG rno:04940 NCBI chr20:4,851,889...4,854,677
Ensembl chr20:4,852,496...4,854,677
JBrowse link
G Prf1 perforin 1 IEA KEGG rno:04940 NCBI chr20:30,915,294...30,920,804
Ensembl chr20:30,915,213...30,921,382
JBrowse link
G Ptprn protein tyrosine phosphatase, receptor type, N IEA KEGG rno:04940 NCBI chr 9:82,446,626...82,462,314
Ensembl chr 9:82,446,633...82,461,903
JBrowse link
G Ptprn2 protein tyrosine phosphatase, receptor type N2 IEA KEGG rno:04940 NCBI chr 6:144,384,773...145,133,042
Ensembl chr 6:144,384,773...145,133,042
JBrowse link
G RT1-A1 RT1 class Ia, locus A1 IEA KEGG rno:04940 NCBI chr20:5,414,463...5,418,012
Ensembl chr20:5,351,605...5,421,098
JBrowse link
G RT1-A2 RT1 class Ia, locus A2 IEA KEGG rno:04940 NCBI chr20:5,374,990...5,378,536
Ensembl chr20:5,374,985...5,378,539
JBrowse link
G RT1-A3 RT1 class I, locus A3 IEA KEGG rno:04940
G RT1-Ba RT1 class II, locus Ba IEA KEGG rno:04940 NCBI chr20:4,066,133...4,070,726
Ensembl chr20:4,066,132...4,070,721
JBrowse link
G RT1-Bb RT1 class II, locus Bb IEA KEGG rno:04940 NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711
JBrowse link
G RT1-CE1 RT1 class I, locus1 IEA KEGG rno:04940 NCBI chr20:4,638,235...4,792,390
Ensembl chr20:4,638,663...4,943,564
JBrowse link
G RT1-CE10 RT1 class I, locus CE10 IEA KEGG rno:04940 NCBI chr20:129,192...157,689
Ensembl chr20:154,074...157,861
JBrowse link
G RT1-CE11 RT1 class I, locus CE11 IEA KEGG rno:04940
G RT1-CE12 RT1 class I, locus CE12 IEA KEGG rno:04940
G RT1-CE13 RT1 class I, locus CE13 IEA KEGG rno:04940
G RT1-CE14 RT1 class I, locus CE14 IEA KEGG rno:04940
G RT1-CE15 RT1 class I, locus CE15 IEA KEGG rno:04940
G RT1-CE16 RT1 class I, locus CE16 IEA KEGG rno:04940
G RT1-CE2 RT1 class I, locus CE2 IEA KEGG rno:04940 NCBI chr20:4,771,960...4,774,886 JBrowse link
G RT1-CE3 RT1 class I, locus CE3 IEA KEGG rno:04940 NCBI chr20:4,918,047...4,943,603
Ensembl chr20:4,931,965...4,935,372
JBrowse link
G RT1-CE4 RT1 class I, locus CE4 IEA KEGG rno:04940 NCBI chr20:4,918,523...4,921,339
Ensembl chr20:4,673,658...4,935,887
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 IEA KEGG rno:04940 NCBI chr20:4,892,702...4,896,993
Ensembl chr20:4,892,702...4,896,991
JBrowse link
G RT1-CE7 RT1 class I, locus CE7 IEA KEGG rno:04940 NCBI chr20:4,695,765...4,698,712
Ensembl chr20:4,694,472...4,896,970
JBrowse link
G RT1-Cl RT1 class Ib, locus Cl IEA KEGG rno:04940
G RT1-Da RT1 class II, locus Da IEA KEGG rno:04940 NCBI chr20:4,127,644...4,132,616
Ensembl chr20:4,127,644...4,132,616
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 IEA KEGG rno:04940 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190
JBrowse link
G RT1-DMa RT1 class II, locus DMa IEA KEGG rno:04940 NCBI chr20:3,935,512...3,938,915
Ensembl chr20:5,240,975...5,244,386
JBrowse link
G RT1-DMb RT1 class II, locus DMb IEA KEGG rno:04940 NCBI chr20:3,945,383...3,952,838
Ensembl chr20:5,227,045...5,234,290
JBrowse link
G RT1-DOa RT1 class II, locus DOa IEA KEGG rno:04940 NCBI chr20:3,889,106...3,892,360
Ensembl chr20:3,889,370...3,892,449
JBrowse link
G RT1-DOb RT1 class II, locus DOb IEA KEGG rno:04940 NCBI chr20:4,020,273...4,026,398
Ensembl chr20:4,020,317...4,026,346
JBrowse link
G RT1-EC2 RT1 class Ib, locus EC2 IEA KEGG rno:04940
G RT1-Ha RT1 class II, locus Ha IEA KEGG rno:04940 NCBI chr20:3,875,478...3,885,140
Ensembl chr20:3,875,706...3,881,461
JBrowse link
G RT1-M1-2 RT1 class I, locus M1, gene 2 IEA KEGG rno:04940 NCBI chr20:2,406,898...2,443,509
Ensembl chr20:2,408,025...2,409,927
JBrowse link
G RT1-M1-4 RT1 class I, locus M1, gene 4 IEA KEGG rno:04940 NCBI chr20:2,387,596...2,391,253 JBrowse link
G RT1-M10-1 RT1 class I, locus M10, gene 1 IEA KEGG rno:04940 NCBI chr20:2,482,637...2,489,529 JBrowse link
G RT1-M2 RT1 class Ib, locus M2 IEA KEGG rno:04940 NCBI chr20:1,337,242...1,339,488
Ensembl chr20:1,337,149...1,339,488
JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 IEA KEGG rno:04940 NCBI chr20:1,814,661...1,833,033
Ensembl chr20:1,814,661...1,818,800
JBrowse link
G RT1-M4 RT1 class Ib, locus M4 IEA KEGG rno:04940 NCBI chr20:2,043,710...2,048,575
Ensembl chr20:2,043,719...2,048,609
JBrowse link
G RT1-M6-1 RT1 class I, locus M6, gene 1 IEA KEGG rno:04940 NCBI chr20:2,057,863...2,060,794
Ensembl chr20:2,057,689...2,079,467
JBrowse link
G RT1-M6-2 RT1 class I, locus M6, gene 2 IEA KEGG rno:04940 NCBI chr20:2,075,796...2,079,183
Ensembl chr20:2,076,267...2,081,885
JBrowse link
G RT1-N1 RT1 class Ib, locus N1 IEA KEGG rno:04940
G RT1-N2 RT1 class Ib, locus N2 IEA KEGG rno:04940 NCBI chr20:3,146,579...3,150,852
Ensembl chr20:3,146,856...3,150,852
JBrowse link
G RT1-N3 RT1 class Ib, locus N3 IEA KEGG rno:04940 NCBI chr20:3,166,793...3,170,945
Ensembl chr20:3,167,079...3,170,945
JBrowse link
G RT1-O1 RT1 class Ib, locus O1 IEA KEGG rno:04940 NCBI chr20:3,160,535...3,162,939
Ensembl chr20:3,162,039...3,162,939
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 IEA KEGG rno:04940 NCBI chr20:3,176,124...3,180,825
Ensembl chr20:3,176,107...3,179,818
JBrowse link
G RT1-T18 RT1 class Ib, locus T18 IEA KEGG rno:04940 NCBI chr20:3,113,026...3,114,031 JBrowse link
G RT1-T24-1 RT1 class I, locus T24, gene 1 IEA KEGG rno:04940 NCBI chr20:3,269,315...3,282,523
Ensembl chr20:3,242,492...3,282,523
JBrowse link
G RT1-T24-4 RT1 class I, locus T24, gene 4 IEA KEGG rno:04940 NCBI chr20:3,189,457...3,197,457
Ensembl chr20:3,189,473...3,197,457
JBrowse link
G Tnf tumor necrosis factor IEA KEGG rno:04940 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
type 2 diabetes mellitus pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 ISO
IEA
DNA:missense mutation::A1369S (human) KEGG PMID:17259403 rno:04930, RGD:2313628 NCBI chr 1:102,110,708...102,191,287
Ensembl chr 1:102,110,708...102,191,287
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing IEA KEGG rno:04930 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Akt2 AKT serine/threonine kinase 2 ISO RGD PMID:15166380 RGD:2313408 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A IEA KEGG rno:04930 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550
JBrowse link
G Cacna1b calcium voltage-gated channel subunit alpha1 B IEA KEGG rno:04930 NCBI chr 3:1,740,026...1,924,959
Ensembl chr 3:1,740,024...1,924,827
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C IEA KEGG rno:04930 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D IEA KEGG rno:04930 NCBI chr16:6,110,294...6,405,022
Ensembl chr16:6,112,150...6,405,117
JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E IEA KEGG rno:04930 NCBI chr13:71,899,445...72,534,992
Ensembl chr13:71,906,702...72,367,980
JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G IEA KEGG rno:04930 NCBI chr10:82,129,071...82,197,828
Ensembl chr10:82,129,506...82,197,848
JBrowse link
G Gck glucokinase IEA KEGG rno:04930 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
JBrowse link
G Hk1 hexokinase 1 IEA KEGG rno:04930 NCBI chr20:31,911,460...31,979,780
Ensembl chr20:31,912,262...31,956,649
JBrowse link
G Hk2 hexokinase 2 IEA KEGG rno:04930 NCBI chr 4:113,559,396...113,609,897
Ensembl chr 4:113,559,427...113,610,243
JBrowse link
G Hk3 hexokinase 3 IEA KEGG rno:04930 NCBI chr17:10,134,726...10,152,976
Ensembl chr17:10,137,974...10,152,956
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta IEA KEGG rno:04930 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Ins1 insulin 1 IEA KEGG rno:04930 NCBI chr 1:272,799,784...272,800,351
Ensembl chr 1:272,799,784...272,800,347
JBrowse link
G Ins2 insulin 2 ISO
IEA
KEGG PMID:9809695 rno:04930, RGD:2313694 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Insr insulin receptor ISO
IEA
KEGG PMID:9809695 rno:04930, RGD:2313694 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414
JBrowse link
G Irs1 insulin receptor substrate 1 IEA KEGG rno:04930 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Irs2 insulin receptor substrate 2 IEA KEGG rno:04930 NCBI chr16:83,824,515...83,848,569
Ensembl chr16:83,824,430...83,848,684
JBrowse link
G Irs3 insulin receptor substrate 3 IEA KEGG rno:04930 NCBI chr12:22,120,305...22,125,103
Ensembl chr12:22,122,953...22,125,091
JBrowse link
G Irs4 insulin receptor substrate 4 IEA KEGG rno:04930 NCBI chr  X:113,003,824...113,018,088 JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 ISO
IEA
polymorphisms in the human gene are linked to altered insulin secretion; E23K polymorphism appears to confer susceptibility to diabetes type-2 in Caucasian population
DNA:missense mutation::p.E23K (human)
KEGG PMID:15565284, PMID:17259403 rno:04930, RGD:2313610, RGD:2313628 NCBI chr 1:102,103,093...102,107,134
Ensembl chr 1:102,103,094...102,106,127
JBrowse link
G Mafa MAF bZIP transcription factor A IEA KEGG rno:04930 NCBI chr 7:116,779,368...116,781,815
Ensembl chr 7:116,780,681...116,781,766
JBrowse link
G Mapk1 mitogen activated protein kinase 1 IEA KEGG rno:04930 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk10 mitogen activated protein kinase 10 IEA KEGG rno:04930 NCBI chr14:8,079,955...8,371,508
Ensembl chr14:8,080,275...8,368,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 IEA KEGG rno:04930 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IEA KEGG rno:04930 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IEA KEGG rno:04930 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mtor mechanistic target of rapamycin kinase IEA KEGG rno:04930 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 IEA KEGG rno:04930 NCBI chr12:9,496,044...9,501,211
Ensembl chr12:9,496,044...9,501,213
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha IEA KEGG rno:04930 NCBI chr 2:118,831,350...118,861,456
Ensembl chr 2:118,831,350...118,861,454
JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta IEA KEGG rno:04930 NCBI chr 8:107,275,849...107,381,088
Ensembl chr 8:107,275,725...107,380,933
JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta IEA KEGG rno:04930 NCBI chr 5:166,602,053...166,628,028
Ensembl chr 5:166,602,053...166,628,028
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 IEA KEGG rno:04930 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 IEA KEGG rno:04930 NCBI chr16:20,415,109...20,424,982
Ensembl chr16:20,416,432...20,424,980
JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 IEA KEGG rno:04930 NCBI chr 5:135,069,972...135,145,633
Ensembl chr 5:135,074,297...135,142,488
JBrowse link
G Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 IEA KEGG rno:04930 NCBI chr10:55,013,686...55,078,986
Ensembl chr10:55,013,703...55,080,421
JBrowse link
G Pklr pyruvate kinase L/R IEA KEGG rno:04930 NCBI chr 2:188,449,158...188,458,034
Ensembl chr 2:188,449,210...188,459,592
JBrowse link
G Prkcd protein kinase C, delta IEA KEGG rno:04930 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746
JBrowse link
G Prkce protein kinase C, epsilon IEA KEGG rno:04930 NCBI chr 6:9,483,400...9,973,396
Ensembl chr 6:9,790,422...9,973,396
JBrowse link
G Prkcz protein kinase C, zeta IEA KEGG rno:04930 NCBI chr 5:172,658,071...172,769,492
Ensembl chr 5:172,658,748...172,769,421
JBrowse link
G Slc2a2 solute carrier family 2 member 2 IEA KEGG rno:04930 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
JBrowse link
G Slc2a4 solute carrier family 2 member 4 IEA KEGG rno:04930 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Socs1 suppressor of cytokine signaling 1 IEA KEGG rno:04930 NCBI chr10:4,956,795...4,958,472
Ensembl chr10:4,957,326...4,958,461
JBrowse link
G Socs2 suppressor of cytokine signaling 2 IEA KEGG rno:04930 NCBI chr 7:36,495,496...36,500,878
Ensembl chr 7:36,495,480...36,499,784
JBrowse link
G Socs3 suppressor of cytokine signaling 3 IEA KEGG rno:04930 NCBI chr10:106,973,863...106,976,969
Ensembl chr10:106,975,178...106,976,040
JBrowse link
G Socs4 suppressor of cytokine signaling 4 IEA KEGG rno:04930 NCBI chr15:24,056,383...24,070,868
Ensembl chr15:24,056,383...24,070,857
JBrowse link
G Tnf tumor necrosis factor IEA KEGG rno:04930 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6103
    disease pathway 1953
      endocrine system disease pathway 145
        adrenal gland disease pathway + 10
        diabetes mellitus pathway + 135
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.