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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:prostaglandin biosynthetic pathway
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Accession:PW:0001532 term browser browse the term
Definition:Those metabolic reactions involved in the synthesis of prostaglandins - a class of eicosanoid prostanoids with several members, exerting a range of important functions in the immune and cardiovascular systems.
Synonyms:related_synonym: prostaglandin biosynthetic process



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prostaglandin biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1A1 aldo-keto reductase family 1 member A1 IDA RGD PMID:23747692 RGD:8552778 NCBI chr 1:45,550,826...45,570,049
Ensembl chr 1:45,550,543...45,570,049
JBrowse link
G AKR1B1 aldo-keto reductase family 1 member B IDA RGD PMID:23747692 RGD:8552778 NCBI chr 7:134,442,350...134,459,239
Ensembl chr 7:134,442,356...134,459,284
JBrowse link
G AKR1C3 aldo-keto reductase family 1 member C3 TAS RGD PMID:12432932 RGD:8552774 NCBI chr10:5,048,781...5,107,686
Ensembl chr10:5,035,354...5,107,686
JBrowse link
G CBR1 carbonyl reductase 1 TAS RGD PMID:12432932 RGD:8552774 NCBI chr21:36,070,024...36,073,164
Ensembl chr21:36,069,941...36,073,166
JBrowse link
G HPGDS hematopoietic prostaglandin D synthase TAS RGD PMID:23063076 PMID:22679221 RGD:8552701, RGD:8552712 NCBI chr 4:94,298,535...94,342,836
Ensembl chr 4:94,298,535...94,342,876
JBrowse link
G PRXL2B peroxiredoxin like 2B ISO RGD PMID:18006499 RGD:8552775 NCBI chr 1:2,586,523...2,591,468
Ensembl chr 1:2,586,491...2,591,469
JBrowse link
G PTGDS prostaglandin D2 synthase TAS RGD PMID:23063076 PMID:22679221 RGD:8552701, RGD:8552712 NCBI chr 9:136,977,504...136,981,742
Ensembl chr 9:136,975,092...136,981,742
JBrowse link
G PTGES prostaglandin E synthase TAS RGD PMID:23063076 PMID:22679221 RGD:8552701, RGD:8552712 NCBI chr 9:129,738,349...129,753,042
Ensembl chr 9:129,738,331...129,753,042
JBrowse link
G PTGES2 prostaglandin E synthase 2 TAS RGD PMID:23063076 PMID:22679221 RGD:8552701, RGD:8552712 NCBI chr 9:128,120,693...128,128,440
Ensembl chr 9:128,120,693...128,128,462
JBrowse link
G PTGES3 prostaglandin E synthase 3 TAS RGD PMID:23063076 PMID:22679221 RGD:8552701, RGD:8552712 NCBI chr12:56,663,349...56,688,284
Ensembl chr12:56,663,341...56,688,408
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 5957
    classic metabolic pathway 1803
      lipid metabolic pathway 431
        eicosanoid metabolic pathway 18
          prostanoid metabolic pathway 14
            prostaglandin metabolic pathway 10
              prostaglandin biosynthetic pathway 10
Path 2
Term Annotations click to browse term
  pathway 5957
    classic metabolic pathway 1803
      lipid metabolic pathway 431
        fatty acid metabolic pathway 143
          arachidonic acid metabolic pathway 69
            cyclooxygenase mediated pathway of arachidonic acid metabolism 16
              prostaglandin metabolic pathway 10
                prostaglandin biosynthetic pathway 10
paths to the root