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ONTOLOGY REPORT - ANNOTATIONS


Term:prostaglandin I2 signaling pathway
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Accession:PW:0001531 term browser browse the term
Definition:Prostaglandin I2 signaling exerts potent vasodilator and anti-thrombic effects. Its actions oppose those of thromboxane A2, the other prostanoid important for the cardiovascular system homeostasis.
Synonyms:exact_synonym: prostacyclin signaling pathway
 related_synonym: SMP:00354


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prostaglandin I2 signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adcy2 adenylate cyclase 2 JBrowse link 13 68,620,043 68,999,600 RGD:10402751
G Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus JBrowse link 2 174,284,320 174,346,744 RGD:10402751
G Gnb1 guanine nucleotide binding protein (G protein), beta 1 JBrowse link 4 155,491,300 155,559,269 RGD:10402751
G Gng12 guanine nucleotide binding protein (G protein), gamma 12 JBrowse link 6 66,896,397 67,021,361 RGD:10402751
G Myl3 myosin, light polypeptide 3 JBrowse link 9 110,763,678 110,769,802 RGD:10402751
G Mylk myosin, light polypeptide kinase JBrowse link 16 34,745,199 35,002,436 RGD:10402751
G Prkacb protein kinase, cAMP dependent, catalytic, beta JBrowse link 3 146,729,579 146,812,946 RGD:10402751
G Ptgir prostaglandin I receptor (IP) JBrowse link 7 16,906,490 16,910,905 RGD:10402751

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6011
    signaling pathway 2476
      lipid signaling pathway 208
        eicosanoid signaling pathway 62
          prostanoid signaling pathway 9
            prostaglandin signaling pathway 9
              prostaglandin I2 signaling pathway 8
Path 2
Term Annotations click to browse term
  pathway 6011
    signaling pathway 2476
      hormone signaling pathway 557
        lipid hormone signaling pathway 149
          eicosanoid signaling pathway 62
            prostanoid signaling pathway 9
              prostaglandin signaling pathway 9
                prostaglandin I2 signaling pathway 8
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.