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ONTOLOGY REPORT - ANNOTATIONS


Term:prostaglandin I2 signaling pathway
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Accession:PW:0001531 term browser browse the term
Definition:Prostaglandin I2 signaling exerts potent vasodilator and anti-thrombic effects. Its actions oppose those of thromboxane A2, the other prostanoid important for the cardiovascular system homeostasis.
Synonyms:exact_synonym: prostacyclin signaling pathway
 related_synonym: SMP:00354


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prostaglandin I2 signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adcy2 adenylate cyclase 2 JBrowse link 1 37,043,071 37,698,390 RGD:10402751
G Gnas GNAS complex locus JBrowse link 3 172,374,957 172,434,988 RGD:10402751
G Gnb1 G protein subunit beta 1 JBrowse link 5 172,914,025 172,981,403 RGD:10402751
G Gng12 G protein subunit gamma 12 JBrowse link 4 97,634,925 97,763,478 RGD:10402751
G Myl3 myosin light chain 3 JBrowse link 8 119,030,852 119,036,996 RGD:10402751
G Mylk myosin light chain kinase JBrowse link 11 69,013,060 69,260,039 RGD:10402751
G Prkacb protein kinase cAMP-activated catalytic subunit beta JBrowse link 2 252,602,197 252,691,886 RGD:10402751
G Ptgir prostaglandin I2 receptor JBrowse link 1 78,833,449 78,835,832 RGD:10402751

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6016
    signaling pathway 2585
      lipid signaling pathway 275
        eicosanoid signaling pathway 137
          prostanoid signaling pathway 9
            prostaglandin signaling pathway 9
              prostaglandin I2 signaling pathway 8
Path 2
Term Annotations click to browse term
  pathway 6016
    signaling pathway 2585
      hormone signaling pathway 619
        lipid hormone signaling pathway 223
          eicosanoid signaling pathway 137
            prostanoid signaling pathway 9
              prostaglandin signaling pathway 9
                prostaglandin I2 signaling pathway 8
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.