PATHWAY ONTOLOGY - ANNOTATIONS
The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml ).
Term: paracetamol pharmacokinetics pathway
Accession: PW:0001525
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Definition: The pathway of processing - absorption, distribution, metabolism or elimination - of paracetamol, a widely used analgesic known as acetaminophen. Genetic variations can result in changes in the availability of the drug.
Synonyms: exact_synonym: acetaminophen pharmacokinetics pathway
related_synonym: SMP:00640
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Abcb1a
ATP binding cassette subfamily B member 1A
ISO
SMPDB
SMP:00640
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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Abcc1
ATP binding cassette subfamily C member 1
ISO
SMPDB
SMP:00640
NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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Abcc2
ATP binding cassette subfamily C member 2
TAS
RGD
PMID:23462933
RGD:8552693
NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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Abcc3
ATP binding cassette subfamily C member 3
TAS
RGD
PMID:23462933
RGD:8552693
NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
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Abcc4
ATP binding cassette subfamily C member 4
TAS ISO
SMPDB RGD
PMID:23462933
SMP:00640, RGD:8552693
NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
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Abcc5
ATP binding cassette subfamily C member 5
ISO
SMPDB
SMP:00640
NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
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Abcg2
ATP binding cassette subfamily G member 2
TAS ISO
SMPDB RGD
PMID:23462933
SMP:00640, RGD:8552693
NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
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Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
ISO
SMPDB
SMP:00640
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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Cyp2d4
cytochrome P450, family 2, subfamily d, polypeptide 4
ISO
SMPDB
SMP:00640
NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
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Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
ISO
SMPDB RGD
PMID:23462933
SMP:00640, RGD:8552693
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
ISO
SMPDB
SMP:00640
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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Dnajb11
DnaJ heat shock protein family (Hsp40) member B11
ISO
SMPDB
SMP:00640
NCBI chr11:78,151,750...78,168,259
Ensembl chr11:78,150,429...78,180,407
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Erp29
endoplasmic reticulum protein 29
ISO
SMPDB
SMP:00640
NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
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Gstp1
glutathione S-transferase pi 1
ISO
SMPDB
SMP:00640
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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Gstt1
glutathione S-transferase theta 1
ISO
SMPDB
SMP:00640
NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
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Hsp90b1
heat shock protein 90 beta family member 1
ISO
SMPDB
SMP:00640
NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
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Hspa5
heat shock protein family A (Hsp70) member 5
ISO
SMPDB
SMP:00640
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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Hyou1
hypoxia up-regulated 1
ISO
SMPDB
SMP:00640
NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186
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Pdia2
protein disulfide isomerase family A, member 2
ISO
SMPDB
SMP:00640
NCBI chr10:15,215,824...15,218,937
Ensembl chr10:15,215,824...15,220,931
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Pdia4
protein disulfide isomerase family A, member 4
ISO
SMPDB
SMP:00640
NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107
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Pdia6
protein disulfide isomerase family A, member 6
ISO
SMPDB
SMP:00640
NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613
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Ppib
peptidylprolyl isomerase B
ISO
SMPDB
SMP:00640
NCBI chr 8:66,603,877...66,609,734
Ensembl chr 8:66,603,861...66,630,428
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Sdf2l1
stromal cell-derived factor 2-like 1
ISO
SMPDB
SMP:00640
NCBI chr11:83,872,659...83,874,902
Ensembl chr11:83,872,659...83,874,902
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Sult1a1
sulfotransferase family 1A member 1
ISO
SMPDB
SMP:00640
NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
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Sult1e1
sulfotransferase family 1E member 1
ISO
SMPDB RGD
PMID:23462933
SMP:00640, RGD:8552693
NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275
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Sult2a1
sulfotransferase family 2A member 1
ISO
SMPDB
SMP:00640
NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134
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Ugt1a1
UDP glucuronosyltransferase family 1 member A1
ISO
SMPDB RGD
PMID:23462933
SMP:00640, RGD:8552693
NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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Ugt1a6
UDP glucuronosyltransferase family 1 member A6
ISO
SMPDB RGD
PMID:23462933
SMP:00640, RGD:8552693
NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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Ugt1a9
UDP glucuronosyltransferase family 1 member A9
ISO
SMPDB
SMP:00640
NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all