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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:altered visual phototransduction pathway
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Accession:PW:0001495 term browser browse the term
Definition:Alterations in the visual phototransduction signaling have been linked to a number conditions such as retinits pigmentosa (RP), Bardet-Biedl syndrome (BBS), macular degeneration and others. More than 200 point mutations in rhodopsin account for ~25% of the autosomal dominant type of RP.
Synonyms:related_synonym: Diseases associated with visual transduction
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altered visual phototransduction pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CNGA1 cyclic nucleotide gated channel subunit alpha 1 ISO RGD PMID:20212494 RGD:8547536 NCBI chr 8:37,896,460...37,968,935
Ensembl chr 8:37,896,459...37,969,344 		JBrowse link
G CNGB1 cyclic nucleotide gated channel subunit beta 1 ISO RGD PMID:20212494 RGD:8547536 NCBI chr 6:19,752,734...19,865,830 JBrowse link
G GUCA1B guanylate cyclase activator 1B ISO RGD PMID:20212494 RGD:8547536 NCBI chr 7:37,297,901...37,311,158
Ensembl chr 7:37,297,908...37,310,170 		JBrowse link
G PDE6A phosphodiesterase 6A ISO RGD PMID:20212494 RGD:8547536 NCBI chr 2:150,926,652...150,986,050
Ensembl chr 2:150,927,770...150,985,318 		JBrowse link
G PDE6B phosphodiesterase 6B ISO RGD PMID:20212494 RGD:8547536 NCBI chr 8:80,378...111,960
Ensembl chr 8:80,378...110,672 		JBrowse link
G PDE6G phosphodiesterase 6G ISO RGD PMID:20212494 RGD:8547536 NCBI chr12:1,235,886...1,239,808
Ensembl chr12:1,236,210...1,239,306 		JBrowse link
G RHO rhodopsin ISO RGD PMID:20212494 RGD:8547536 NCBI chr13:68,908,578...68,913,651
Ensembl chr13:68,908,578...68,913,651 		JBrowse link
G SAG S-antigen visual arrestin ISO RGD PMID:20212494 RGD:8547536 NCBI chr15:133,704,975...133,741,844
Ensembl chr15:133,705,008...133,741,798 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4047
    signaling pathway 1931
      altered signaling pathway 102
        altered photosignal transduction pathway 8
          altered visual phototransduction pathway 8
Path 2
Term Annotations click to browse term
  pathway 4047
    regulatory pathway 2501
      homeostasis pathway 1301
        organic chemical homeostasis pathway 363
          vitamin homeostasis 100
            vitamin A homeostasis 100
              visual phototransduction pathway 31
                altered visual phototransduction pathway 8
paths to the root