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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:cerium oxide nanoparticle response pathway
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Accession:PW:0001439 term browser browse the term
Definition:A pathway triggered by exposure to cerium oxide nanoparticles, also known as nanoceria. Like other nanoparticles, nanoceria has a broad range of applications. A peculiar feature is the anti-oxidant property; by catalytically reacting with superoxide and hydrogen peroxide, it mimics the activities of superoxide dismutase and catalase enzymes. In addition, beneficial effects on cell differentiation and dopamine production have been shown. However, toxic effects have also been demonstrated.
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cerium oxide nanoparticle response pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf2 fibroblast growth factor 2 ISO RGD PMID:23478040 RGD:7364779 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 ISO RGD PMID:23478040 RGD:7364779 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449 		JBrowse link
Term paths to the root
Path 1
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  pathway 6106
    regulatory pathway 3881
      cellular detoxification pathway 157
        toxin and toxicant response pathway 23
          nanomaterial response pathway 8
            cerium oxide nanoparticle response pathway 2
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