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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:abciximab pharmacodynamics pathway
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Accession:PW:0001420 term browser browse the term
Definition:The pathway of abciximab-target interaction and of the biochemical or physiological responses to drug. Abciximab is an antagonist of the integrin alpha2b/beta3 complex found on platelets. Genetic variations can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: SMP:00265


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abciximab pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itga2b integrin subunit alpha 2b ISO SMPDB SMP:00265 NCBI chr10:87,408,532...87,426,055
Ensembl chr10:87,408,536...87,426,168 		JBrowse link
G Itgb3 integrin subunit beta 3 ISO SMPDB SMP:00265 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    drug pathway 397
      blood and blood forming organs drug pathway 62
        antithrombotic drug pathway 62
          antiplatelet drug pathway 37
            abciximab drug pathway 2
              abciximab pharmacodynamics pathway 2
paths to the root