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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:altered chromatin modification pathway
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Accession:PW:0001404 term browser browse the term
Definition:A chromatin modification pathway that deviate from what its normal course should be. Mutations in the writer, reader or eraser categories of chromatin modification have been implicated in cancer.


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altered DNA modification pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mbd4 methyl-CpG binding domain 4 DNA glycosylase ISO in silico assessment of loss of DNA-protein interactions and observed enhancement of DNA repair capacity (DRC) in the context of nucleotide excision repair (NER) pathway for SNP RGD PMID:24004570 RGD:9588971 NCBI chr 4:148,893,049...148,904,833
Ensembl chr 4:148,894,280...148,904,982 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    regulatory pathway 3867
      pathway pertinent to DNA replication and repair, cell cycle, maintenance of genomic integrity, RNA and protein biosynthesis 1738
        chromatin modification/remodeling pathway 268
          altered chromatin remodeling/modification pathway 6
            altered chromatin modification pathway 1
              altered DNA modification pathway 1
              altered histone modification pathway 0
Path 2
Term Annotations click to browse term
  pathway 6092
    regulatory pathway 3867
      pathway pertinent to DNA replication and repair, cell cycle, maintenance of genomic integrity, RNA and protein biosynthesis 1738
        DNA damage response pathway 405
          DNA repair pathway 384
            chromatin modification/remodeling pathway 268
              chromatin modification pathway 206
                altered chromatin modification pathway 1
                  altered DNA modification pathway 1
                  altered histone modification pathway 0
paths to the root