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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:cardiolipin metabolic pathway
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Accession:PW:0001344 term browser browse the term
Definition:Those metabolic reactions involved in the synthesis, utilization and/or degradation of cardiolipin. The molecule is derived from phosphatidylglycerol as an immature cardiolipin, and further remodeled by phospholipases. Cardiolipin is important for a range of mitochondrial functions.
Synonyms:related_synonym: cardiolipin metabolic process
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cardiolipin metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ckmt1a creatine kinase, mitochondrial 1A ISO RGD PMID:24769127 RGD:10400850 NCBI chrNW_004936471:6,754,514...6,760,025 JBrowse link
G Nme4 NME/NM23 nucleoside diphosphate kinase 4 ISO RGD PMID:24769127 RGD:10400850 NCBI chrNW_004936501:553,931...557,744 JBrowse link
G Tafazzin tafazzin, phospholipid-lysophospholipid transacylase ISO RGD PMID:24769127 RGD:10400850 NCBI chrNW_004936809:1,160,265...1,168,956
Ensembl chrNW_004936809:1,160,247...1,171,097 		JBrowse link
cardiolipin biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crls1 cardiolipin synthase 1 ISO RGD PMID:24769127 RGD:10400850 NCBI chrNW_004936485:13,050,401...13,070,197 JBrowse link
G Pgs1 phosphatidylglycerophosphate synthase 1 ISO RGD PMID:24769127 RGD:10400850 NCBI chrNW_004936594:2,934,450...2,989,328
Ensembl chrNW_004936594:2,951,150...2,989,347 		JBrowse link
G Ptpmt1 protein tyrosine phosphatase mitochondrial 1 ISO RGD PMID:24769127 RGD:10400850 NCBI chrNW_004936562:1,680,131...1,689,125
Ensembl chrNW_004936562:1,680,164...1,690,062 		JBrowse link
G Tamm41 TAM41 mitochondrial translocator assembly and maintenance homolog ISO RGD PMID:24769127 RGD:10400850 NCBI chrNW_004936602:1,694,881...1,726,616 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 3951
    classic metabolic pathway 974
      lipid metabolic pathway 241
        glycerophospholipid metabolic pathway 56
          phosphatidylglycerol metabolic pathway 7
            cardiolipin metabolic pathway 7
              cardiolipin biosynthetic pathway 4
paths to the root